Caregiver BurdenCarePairNCT06418971
Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.
A study testing CarePair in people with Caregiver Burden and Caregiver Burnout, run by University of Southern California at 1 site in United States.
Trial summary
The purpose of this study is to develop and test CarePair, a mobile application-based needs assessment and service referral platform for family caregivers of persons with dementia designed to alleviate stress and promote psychosocial well being. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Caregiver Burden, Caregiver Burnout, Dementia
- What is being tested?
- CarePair
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteUnited States
- Study dates
- 15 Sep 2025to 31 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Currently a primary caregiver of a community-dwelling PwD
- Provides at least 10 hours of care per week
- ≥18 years of age
- Fluent in English
- Both the caregiver and care-recipient reside in and/or can easily access one of the following cities/areas: New York City, New York (NY); Long Island, NY; Westchester County, NY; Seattle, Washington (WA); Los Angeles, California (CA)
- Provides at least 10 hours of care per week
Show all 11Show fewer
- Has provided care for at least 6 months
- Able to use the internet and has internet access
- Owns and can operate a smartphone
- Able and willing to provide their informed consent to participate for the six-week study duration
- Does not self-report any cognitive impairments
Who cannot join
- Not currently the primary caregiver of a community-dwelling person with dementia
- Care-recipient lives in residential care (e.g., assisted living, skilled nursing facility)
- ≤18 years of age
- Not fluent in English
- The caregiver and/or care-recipient resides outside of and/or cannot easily access any of the following cities: New York City (NY); Long Island (NY); Westchester County (NY); Seattle (WA); Los Angeles (CA)
- Provides less than 10 hours of care per week
Show all 11Show fewer
- Has provided care for less than 6 months
- Unable to use the internet or does not have internet access
- Does not own and/or cannot operate a smartphone
- Unable or unwilling to provide informed consent to participate for the six-week study duration
- Self-reports having a cognitive impairment
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Southern California
Los Angeles, California, 90089
Annabelle Greenfield, B.S., 7603307425, ag69282@usc.edu
Francesca Falzarano, PhD
About this study
The purpose of this study is to develop and test CarePair, a mobile application-based needs assessment and service referral platform for family caregivers of persons with dementia designed to alleviate stress and promote psychosocial well being.
The main aims of this study are:
Read more
- To evaluate the feasibility and acceptability of the CarePair mobile application.
- To explore the potential for CarePair to reduce feelings of depression and burden, and improve caregivers' feelings of self-efficacy.
Caregiver participants will be asked to log in and use the CarePair application and complete study activities for a six-week duration. Researchers will compare the intervention group to an attention control comparator to see if application use is associated with improved psychosocial outcomes at follow-up.
Read the detailed description
In 2024, approximately 6.9 million diagnosed cases of Alzheimer's disease and related dementias (ADRD) were reported in the United States, with 83% of the caregiving burden shouldered by unpaid family members or friends. The duration of ADRD varies between 4-20 years, during which individuals often transition into a state of complete dependency. Without family caregivers, the long-term services and support system would be unsustainable. The dearth of accessible support for ADRD caregivers constitutes a significant public health emergency. Caregivers are frequently uncertain of which services are needed, available, and how to gain access - often leaving those most vulnerable without essential support. When queried about service underuse, study respondents who participated in the K99 phase of this project highlighted an information deficit tailored to specific cultures, demographics, and dementia types. They described the excess of online information as overwhelming, often irrelevant, impractical, or unaffordable. Existing technology-based solutions targeted toward enhancing personalized caregiver support are limited. Leveraging continued innovations in technology to inform the training and testing of machine learning algorithms, which can match and update resources while accounting for individual needs, preferences (in-person, virtual), and barriers (e.g., employment, lack of respite care), holds great potential to enhance the precision of service linkage for ADRD caregivers. This R00 project aims to develop, refine, and pilot test CarePair (formerly the Caregiver Resource Room), a mobile application assessment and service referral platform for dementia caregivers. CarePair will leverage innovative machine learning algorithms to holistically evaluate caregivers' evolving needs, their barriers, and preferences to generate personalized service referrals relevant to their areas of identified need. Thus, the specific aims of the R00 are to 1) Use mixed-method and focus group data from the K99 phase to inform the iterative development of the CarePair, which includes a digital self-assessment tool employing machine learning to identify needs, categorize them, and generate targeted service recommendations; 2) Evaluate front- and back-end usability (e.g., via task analysis, heuristic evaluation) of the tool's content, design, features, functionality, and accuracy of service output. Feedback will inform modifications and iterative refinement of the CarePair Version 2.0; 3) Conduct a pilot randomized controlled trial to assess the feasibility, acceptability, and preliminary efficacy of CarePair in enhancing service awareness, addressing unmet needs, and improving mental health. The proposed research aligns with the NIA's strategic initiative to foster research scientists in aging and to develop promising interventions to better engage and support the well-being of ADRD family caregivers.
- Conditions
- Caregiver Burden, Caregiver Burnout, Dementia
- Being tested
- CarePair
- Keywords
- Dementia family caregivers
- Medical subject headings
- Caregiver Burden, Dementia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
CarePairBehavioural
This study will pilot test the feasibility and acceptability of a digital self-assessment and referral tool using machine learning models to enhance service use and address unmet needs in ADRD caregivers.
| Study group | Role | What they receive |
|---|---|---|
| Control Arm | No intervention | Participants randomized to the control arm will receive access to an attention-matched comparator: a digital folder containing the same caregiving articles available in the CarePair app. However, the materials will not be personalized or organized. Participants will be asked to log into the digital folder twice per week and read one article at each login, for a total of 12 logins and articles over the 6-week study period, mirroring the engagement frequency of the intervention group. |
| CarePair Intervention Arm | Experimental | Participants randomized to the intervention arm will receive access to the CarePair app, a needs-based digital platform that delivers tailored recommendations for Alzheimer's disease and related dementias (ADRD) resources designed for family caregivers. These include services and educational articles personalized based on the caregiver's self-reported needs and preferences, with content organized by relevance to each user. Participants will be asked to log into the CarePair app twice per week and engage with one article per login, for a total of 12 logins and articles over the 6-week study period. Receives: Behavioral: CarePair |
What is being measured
The primary outcome is the main question the study is designed to answer.
The Feasibility of the CarePair study as measured by the proportion of family caregivers who complete the study screening survey.
The feasibility of the CarePair study will be measured by the proportion of family caregivers who complete the study screening survey among those who were directly invited to participate the study.
Measured: Enrollment
The Feasibility of the CarePair study as measured by the proportion of family caregivers who consent to participate and are enrolled.
The feasibility of the CarePair study will be measured by the proportion of family caregivers who consent to participate among those who were screened into the study. Participants who consent to participate are then immediately randomized to their assigned condition and thus enrolled.
Measured: Enrollment
The Feasibility of the CarePair study as measured by the proportion of are deemed eligible based on screening criteria.
The feasibility of the CarePair study will be measured by the proportion of family caregivers who are deemed eligible to participate based on screening criteria among those who completed the study's screening survey.
Measured: Enrollment
The Feasibility of the CarePair study as measured by recruitment rates and the proportion of family caregivers that decline participation.
The feasibility of the CarePair study will be measured by the proportion of eligible family caregivers who decline to participate among those who were screened into the study.
Measured: Enrollment
The Feasibility of the CarePair study as measured by participant retention, as indicated by the number of participants lost to follow-up.
Participant retention, as an aspect of feasibility, will be measured by the recorded number of participants number lost to follow-up. A number of the enrolled participants who the study team contacted weekly for 4 weeks, but did not answer or continue participation, will be recorded.
Measured: Enrollment to 6-Week Follow-Up
The Feasibility of the CarePair study as measured by participant retention, as indicated by the number of recorded dropouts.
Participant retention, as an indicator of feasibility, will be assessed by recording the number of participants who withdraw from the study after enrollment
Measured: Enrollment to 6-Week Follow-Up
The Feasibility of the CarePair application as measured by the number of app logins per participant out of total required (minimum= 12).
The feasibility of the application will be measured by the number of times the participant logs in to the CarePair application. The minimum number of logins recommended to the participants is 12 (2x/week for 6 weeks).
Measured: Baseline to 6-Week Follow-Up
The Feasibility of the CarePair application as measured by the number of app interactions per participant out of total required (minimum= 12).
Feasibility of the application will be assessed based on the number of participant interactions with CarePair's features, such as reviewing, rating, taking notes on, or saving services or articles. Participants are asked to log in and engage with the app approximately twice per week over the six-week study period, for a recommended minimum of 12 total interactions.
Measured: Baseline to 6-Week Follow-Up
Application Usability, as measured using the validated System Usability Scale (SUS).
Usability and accessibility of the CarePair application design will be measured using the validated System Usability Scale (SUS). Total scores for the SUS range from 0-100, with higher scores indicative of greater usability. A threshold score of 68 is used to indicate adequate usability.
Measured: 6-Week Follow-Up
Application usability, as measured using the validated User Version of the Mobile App Rating Scale (uMARS).
Usability of the CarePair application will be measured using the validated user version of the Mobile App Rating Scale (uMARS). The uMARS provides a multidimensional assessment of app quality, including engagement, functionality, aesthetics, and information. Scores range from 20 to 100, with higher scores indicating more favorable user evaluations of the app's usability and overall quality.
Measured: 6-Week Follow-Up
The Acceptability of the CarePair application as measured by a survey that measures the participants satisfaction and acceptability of the application.
The acceptability of the CarePair application will be measured by the use of surveys assessing usability, engagement, acceptability, suggestions for improvement.
Participants will be asked to rate their agreement with statements including "I enjoyed my experience using the CarePair application". Response options are rated on a five-point scale from 1-Strongly Disagree to 5-Strongly Agree. Scores range from 9-45, with higher scores indicating greater satisfaction and acceptability.
Measured: 6-Week Follow-Up
The Acceptability of the CarePair application as measured by a qualitative survey that measures the participants satisfaction and acceptability of the application.
The acceptability of the CarePair application will be measured by the use of open-ended items assessing usability, engagement, acceptability, suggestions for improvement. The intervention group participants will be administered five open-ended qualitative items asking for feedback on CarePair. Sample items include: "Would you continue using the CarePair application after this study? Why or why not?"
Measured: 6-Week Follow-Up
Secondary outcomes (6)
Change from Baseline Caregiver Needs scores on a 12-item Needs Assessment
A 12-item caregiver needs assessment will be used to measure family caregivers' care-related needs, such as legal guidance, social support, and education. Total scores range from 12-48, with higher scores representing greater caregiver needs.
Measured: Baseline; 6-Week Follow-Up
Change from Baseline Caregiving Self-Efficacy scores on the 15-item Revised Scale for Caregiving Self-Efficacy
Caregiving Self-Efficacy will be measured using the Revised Scale for Caregiving Self-Efficacy. Total scores range from 0-100, with higher scores indicative of greater feelings of perceived self-efficacy.
Measured: Baseline; 6-Week Follow-Up
Change from Baseline Caregiver Depressive Symptoms as measured by the Patient Health Questionnaire-9 (PHQ-9).
The PHQ-9 will be used to measure family caregiver depressive symptoms. Total scores range from 0-27, with higher scores indicative of greater caregiver depressive symptoms.
Measured: Baseline; 6-Week Follow-Up
Change from Baseline Anxiety scores on the Generalized Anxiety Disorder-7 (GAD-7)
Change in caregivers' anxiety scores will be assessed using the GAD-7. Scores range from 0-21, with higher scores indicating a greater level of anxiety.
Measured: Baseline; 6-Week Follow-Up
Change from Baseline Caregiver Stress as measured by the Kingston Caregiver Stress Scale (KCSS)
The KCSS will be used to measure family caregiver stress. Total scores range from 20-50, with higher scores indicative of greater caregiver stress.
Measured: Baseline; 6-Week Follow-Up
Change from Baseline Quality of Life scores on the 5-item Satisfaction with Life Scale (SWLS)
The SWLS will be used to measure family caregiver quality of life. Total scores range from 5-35, with a score of 20 representing a neutral point on the scale. Higher scores indicate a greater level of satisfaction with life.
Measured: Baseline; 6-Week Follow-Up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 May 2024
- Study start15 Sep 2025
- Primary completion31 Jul 2026 (estimated)
- Study completion31 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Caregiver BurdenStudies of the same condition, open and under way.
- More trials run by University of Southern CaliforniaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Southern California
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Aging (NIA)
- Responsible party
- Principal investigator, Francesca B Falzarano, University of Southern California
- Investigators
- Francesca Falzarano, PhD, Principal investigator, University of Southern California
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06418971
- Sponsor's protocol ID
- UP-25-00690
- Other IDs
- R00AG073509
- Acronym
- CarePair
- Status last verified
- Mar 2026
- First submitted
- 27 Feb 2024
- Last updated
- 5 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Data collected for the CarePair study will only be shared after the investigators have published the data addressing the study's specific aims. Intellectual property and data generated under this project will be administered in accordance with both University of Southern California (USC) and NIH policies, including the NIH Data Sharing Policy and Implementation Guidance. After publication of the investigator's main findings, access to databases and associated software tools generated and the code to create these tools under the project will be available for educational, research and non-profit purposes.
Publications
Falzarano F, Greenfield A, Mason H, Bumbalova K, Rojas E, Bumbalov A. A Mobile Self-Assessment and Referral Platform for Family Caregivers of Individuals With Alzheimer Disease and Related Dementias: Protocol for a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2026 Apr 1;15:e90244. doi: 10.2196/90244.
PubMed 41921130
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.
- ClinicalTrials.gov ID
- NCT06418971
- Acronym / sponsor ID
- CarePair / UP-25-00690
- Conditions
- Caregiver Burden, Caregiver Burnout, Dementia
- Keywords
- Dementia family caregivers
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- University of Southern CaliforniaUniversity, hospital or other
- Collaborators
- National Institute on Aging (NIA)
- Study start
- 15 Sep 2025 (actual)
- Primary completion
- 31 Jul 2026 (estimated)
- Study completion
- 31 Jul 2026 (estimated)
- First posted
- 17 May 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to develop and test CarePair, a mobile application-based needs assessment and service referral platform for family caregivers of persons with dementia designed to alleviate stress and promote psychosocial well being.
The main aims of this study are:
- To evaluate the feasibility and acceptability of the CarePair mobile application.
- To explore the potential for CarePair to reduce feelings of depression and burden, and improve caregivers' feelings of self-efficacy.
Caregiver participants will be asked to log in and use the CarePair application and complete study activities for a six-week duration. Researchers will compare the intervention group to an attention control comparator to see if application use is associated with improved psychosocial outcomes at follow-up.
Detailed description
In 2024, approximately 6.9 million diagnosed cases of Alzheimer's disease and related dementias (ADRD) were reported in the United States, with 83% of the caregiving burden shouldered by unpaid family members or friends. The duration of ADRD varies between 4-20 years, during which individuals often transition into a state of complete dependency. Without family caregivers, the long-term services and support system would be unsustainable. The dearth of accessible support for ADRD caregivers constitutes a significant public health emergency. Caregivers are frequently uncertain of which services are needed, available, and how to gain access - often leaving those most vulnerable without essential support. When queried about service underuse, study respondents who participated in the K99 phase of this project highlighted an information deficit tailored to specific cultures, demographics, and dementia types. They described the excess of online information as overwhelming, often irrelevant, impractical, or unaffordable. Existing technology-based solutions targeted toward enhancing personalized caregiver support are limited. Leveraging continued innovations in technology to inform the training and testing of machine learning algorithms, which can match and update resources while accounting for individual needs, preferences (in-person, virtual), and barriers (e.g., employment, lack of respite care), holds great potential to enhance the precision of service linkage for ADRD caregivers. This R00 project aims to develop, refine, and pilot test CarePair (formerly the Caregiver Resource Room), a mobile application assessment and service referral platform for dementia caregivers. CarePair will leverage innovative machine learning algorithms to holistically evaluate caregivers' evolving needs, their barriers, and preferences to generate personalized service referrals relevant to their areas of identified need. Thus, the specific aims of the R00 are to 1) Use mixed-method and focus group data from the K99 phase to inform the iterative development of the CarePair, which includes a digital self-assessment tool employing machine learning to identify needs, categorize them, and generate targeted service recommendations; 2) Evaluate front- and back-end usability (e.g., via task analysis, heuristic evaluation) of the tool's content, design, features, functionality, and accuracy of service output. Feedback will inform modifications and iterative refinement of the CarePair Version 2.0; 3) Conduct a pilot randomized controlled trial to assess the feasibility, acceptability, and preliminary efficacy of CarePair in enhancing service awareness, addressing unmet needs, and improving mental health. The proposed research aligns with the NIA's strategic initiative to foster research scientists in aging and to develop promising interventions to better engage and support the well-being of ADRD family caregivers.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control Arm | No intervention | –Participants randomized to the control arm will receive access to an attention-matched comparator: a digital folder containing the same caregiving articles available in the CarePair app. However, the materials will not be personalized or organized. Participants will be asked to log into the digital folder twice per week and read one article at each login, for a total of 12 logins and articles over the 6-week study period, mirroring the engagement frequency of the intervention group. |
| CarePair Intervention Arm | Experimental | Behavioral: CarePairParticipants randomized to the intervention arm will receive access to the CarePair app, a needs-based digital platform that delivers tailored recommendations for Alzheimer's disease and related dementias (ADRD) resources designed for family caregivers. These include services and educational articles personalized based on the caregiver's self-reported needs and preferences, with content organized by relevance to each user. Participants will be asked to log into the CarePair app twice per week and engage with one article per login, for a total of 12 logins and articles over the 6-week study period. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (11 listed)
- Currently a primary caregiver of a community-dwelling PwD
- Provides at least 10 hours of care per week
- ≥18 years of age
- Fluent in English
- Both the caregiver and care-recipient reside in and/or can easily access one of the following cities/areas: New York City, New York (NY); Long Island, NY; Westchester County, NY; Seattle, Washington (WA); Los Angeles, California (CA)
Key exclusion criteria (11 listed)
- Not currently the primary caregiver of a community-dwelling person with dementia
- Care-recipient lives in residential care (e.g., assisted living, skilled nursing facility)
- ≤18 years of age
- Not fluent in English
- The caregiver and/or care-recipient resides outside of and/or cannot easily access any of the following cities: New York City (NY); Long Island (NY); Westchester County (NY); Seattle (WA); Los Angeles (CA)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| CarePairThis study will pilot test the feasibility and acceptability of a digital self-assessment and referral tool using machine learning models to enhance service use and address unmet needs in ADRD caregivers. | Behavioural | CarePair Intervention Arm |
Primary outcome
The Feasibility of the CarePair study as measured by the proportion of family caregivers who complete the study screening survey.
Time frame: Enrollment
The feasibility of the CarePair study will be measured by the proportion of family caregivers who complete the study screening survey among those who were directly invited to participate the study.
The Feasibility of the CarePair study as measured by the proportion of family caregivers who consent to participate and are enrolled.
Time frame: Enrollment
The feasibility of the CarePair study will be measured by the proportion of family caregivers who consent to participate among those who were screened into the study. Participants who consent to participate are then immediately randomized to their assigned condition and thus enrolled.
The Feasibility of the CarePair study as measured by the proportion of are deemed eligible based on screening criteria.
Time frame: Enrollment
The feasibility of the CarePair study will be measured by the proportion of family caregivers who are deemed eligible to participate based on screening criteria among those who completed the study's screening survey.
The Feasibility of the CarePair study as measured by recruitment rates and the proportion of family caregivers that decline participation.
Time frame: Enrollment
The feasibility of the CarePair study will be measured by the proportion of eligible family caregivers who decline to participate among those who were screened into the study.
The Feasibility of the CarePair study as measured by participant retention, as indicated by the number of participants lost to follow-up.
Time frame: Enrollment to 6-Week Follow-Up
Participant retention, as an aspect of feasibility, will be measured by the recorded number of participants number lost to follow-up. A number of the enrolled participants who the study team contacted weekly for 4 weeks, but did not answer or continue participation, will be recorded.
The Feasibility of the CarePair study as measured by participant retention, as indicated by the number of recorded dropouts.
Time frame: Enrollment to 6-Week Follow-Up
Participant retention, as an indicator of feasibility, will be assessed by recording the number of participants who withdraw from the study after enrollment
The Feasibility of the CarePair application as measured by the number of app logins per participant out of total required (minimum= 12).
Time frame: Baseline to 6-Week Follow-Up
The feasibility of the application will be measured by the number of times the participant logs in to the CarePair application. The minimum number of logins recommended to the participants is 12 (2x/week for 6 weeks).
The Feasibility of the CarePair application as measured by the number of app interactions per participant out of total required (minimum= 12).
Time frame: Baseline to 6-Week Follow-Up
Feasibility of the application will be assessed based on the number of participant interactions with CarePair's features, such as reviewing, rating, taking notes on, or saving services or articles. Participants are asked to log in and engage with the app approximately twice per week over the six-week study period, for a recommended minimum of 12 total interactions.
Application Usability, as measured using the validated System Usability Scale (SUS).
Time frame: 6-Week Follow-Up
Usability and accessibility of the CarePair application design will be measured using the validated System Usability Scale (SUS). Total scores for the SUS range from 0-100, with higher scores indicative of greater usability. A threshold score of 68 is used to indicate adequate usability.
Application usability, as measured using the validated User Version of the Mobile App Rating Scale (uMARS).
Time frame: 6-Week Follow-Up
Usability of the CarePair application will be measured using the validated user version of the Mobile App Rating Scale (uMARS). The uMARS provides a multidimensional assessment of app quality, including engagement, functionality, aesthetics, and information. Scores range from 20 to 100, with higher scores indicating more favorable user evaluations of the app's usability and overall quality.
The Acceptability of the CarePair application as measured by a survey that measures the participants satisfaction and acceptability of the application.
Time frame: 6-Week Follow-Up
The acceptability of the CarePair application will be measured by the use of surveys assessing usability, engagement, acceptability, suggestions for improvement. Participants will be asked to rate their agreement with statements including "I enjoyed my experience using the CarePair application". Response options are rated on a five-point scale from 1-Strongly Disagree to 5-Strongly Agree. Scores range from 9-45, with higher scores indicating greater satisfaction and acceptability.
The Acceptability of the CarePair application as measured by a qualitative survey that measures the participants satisfaction and acceptability of the application.
Time frame: 6-Week Follow-Up
The acceptability of the CarePair application will be measured by the use of open-ended items assessing usability, engagement, acceptability, suggestions for improvement. The intervention group participants will be administered five open-ended qualitative items asking for feedback on CarePair. Sample items include: "Would you continue using the CarePair application after this study? Why or why not?"
6 secondary outcomes
Change from Baseline Caregiver Needs scores on a 12-item Needs Assessment
Time frame: Baseline; 6-Week Follow-Up
Change from Baseline Caregiving Self-Efficacy scores on the 15-item Revised Scale for Caregiving Self-Efficacy
Time frame: Baseline; 6-Week Follow-Up
Change from Baseline Caregiver Depressive Symptoms as measured by the Patient Health Questionnaire-9 (PHQ-9).
Time frame: Baseline; 6-Week Follow-Up
Change from Baseline Anxiety scores on the Generalized Anxiety Disorder-7 (GAD-7)
Time frame: Baseline; 6-Week Follow-Up
Change from Baseline Caregiver Stress as measured by the Kingston Caregiver Stress Scale (KCSS)
Time frame: Baseline; 6-Week Follow-Up
Change from Baseline Quality of Life scores on the 5-item Satisfaction with Life Scale (SWLS)
Time frame: Baseline; 6-Week Follow-Up
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2026.
- Derived from this study: PubMed 41921130Falzarano F, Greenfield A, Mason H, Bumbalova K, Rojas E, Bumbalov A. A Mobile Self-Assessment and Referral Platform for Family Caregivers of Individuals With Alzheimer Disease and Related Dementias: Protocol for a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2026 Apr 1;15:e90244. doi: 10.2196/90244.
- Individual participant dataSharing planned: Yes. Data collected for the CarePair study will only be shared after the investigators have published the data addressing the study's specific aims. Intellectual property and data generated under this project will be administered in accordance with both University of Southern California (USC) and NIH policies, including the NIH Data Sharing Policy and Implementation Guidance. After publication of the investigator's main findings, access to databases and associated software tools generated and the code to create these tools under the project will be available for educational, research and non-profit purposes.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Francesca Falzarano, PhD principal investigator
University of Southern California
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing CarePair in people with Caregiver Burden and Caregiver Burnout, run by University of Southern California at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 5 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Francesca B Falzarano, PhD (6464812858, falzaran@usc.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The Feasibility of the CarePair study as measured by the proportion of family caregivers who complete the study screening survey. (time frame: Enrollment). The study lists 12 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06418971, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2026.