Acute Myocardial InfarctionMIRON-PRE-xAINCT06423625
Hemorrhagic MI Prediction Score Model
An observational study of Acute Myocardial Infarction, run by Rohan Dharmakumar at 1 site in United States.
Trial summary
Developing a prediction score model for predicting the likelihood of Hemorrhagic MI Read more about this study
- Who is it for?
- Ages 18 to 79 years
- Conditions the study is for
- Acute Myocardial Infarction
- How many people
- 252 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Jun 2023to 20 Dec 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 79 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The study population consists of individuals aged 18 - 80 yrs who have been diagnosed with acute ST-elevation myocardial infarction (STEMI) and are scheduled for emergency percutaneous coronary intervention (PCI).
Who may be able to join
- Age > 18 yrs
- Index MI
- Primary PCI
Who cannot join
- History of prior myocardial infarction,
- Thrombolysis before PCI
- Contraindication to Cardiac MRI
Trial locations and contacts
1 site in 1 country.
United States1 site
Krannert Cardiovascular Research Center, Indiana University School of Medicine
Indianapolis, Indiana, 46202
About this study
Official title: Developing a Prediction Score Model for Predicting the Likelihood of Hemorrhagic MI Before Percutaneous Coronary Reperfusion Therapy
Developing a prediction score model for predicting the likelihood of Hemorrhagic MI
- Conditions
- Acute Myocardial Infarction
- Keywords
- Acute Myocardial Infarction, Prediction Score, Machine Learning, Hemorrhagic MI
What is being measured
The primary outcome is the main question the study is designed to answer.
Hemorrhagic MI
Percentage of MI patients confirmed as Hemorrhagic MI
Measured: Emergency admission to Percutaneous Intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 May 2024
- Study start1 Jun 2023
- Primary completion15 Dec 2025
- Study completion20 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Acute Myocardial InfarctionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 252 participants (actual)
Sponsor and investigators
- Lead sponsor
- Rohan Dharmakumar
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Rohan Dharmakumar, Indiana University
- Investigators
- Keyur P Vora, MD FACC, Principal investigator, Indiana University School of Medicine, Krannert Cardiovascular Research Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06423625
- Sponsor's protocol ID
- 19978d
- Acronym
- MIRON-PRE-xAI
- Status last verified
- Jan 2026
- First submitted
- 16 May 2024
- Last updated
- 6 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Developing a Prediction Score Model for Predicting the Likelihood of Hemorrhagic MI Before Percutaneous Coronary Reperfusion Therapy
- ClinicalTrials.gov ID
- NCT06423625
- Acronym / sponsor ID
- MIRON-PRE-xAI / 19978d
- Conditions
- Acute Myocardial Infarction
- Keywords
- Acute Myocardial Infarction, Prediction Score, Machine Learning, Hemorrhagic MI
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 252 participants (actual)
- Lead sponsor
- Rohan DharmakumarUniversity, hospital or other
- Study start
- 1 Jun 2023 (actual)
- Primary completion
- 15 Dec 2025 (actual)
- Study completion
- 20 Dec 2025 (actual)
- First posted
- 21 May 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Developing a prediction score model for predicting the likelihood of Hemorrhagic MI
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 79 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The study population consists of individuals aged 18 - 80 yrs who have been diagnosed with acute ST-elevation myocardial infarction (STEMI) and are scheduled for emergency percutaneous coronary intervention (PCI).
Key inclusion criteria (3 listed)
- Age > 18 yrs
- Index MI
- Primary PCI
Key exclusion criteria (3 listed)
- History of prior myocardial infarction,
- Thrombolysis before PCI
- Contraindication to Cardiac MRI
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Hemorrhagic MI
Time frame: Emergency admission to Percutaneous Intervention
Percentage of MI patients confirmed as Hemorrhagic MI
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Keyur P Vora, MD FACC principal investigator
Indiana University School of Medicine, Krannert Cardiovascular Research Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Acute Myocardial Infarction, run by Rohan Dharmakumar at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Hemorrhagic MI (time frame: Emergency admission to Percutaneous Intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Jan 2026.