Bone DisorderOSCARNCT06444503
Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies
An observational study of Bone Disorder, run by University Hospital, Toulouse at 1 site in France.
Trial summary
The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies. This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of… Read more about this study
- Who is it for?
- Ages Up to 99 years
- Conditions the study is for
- Bone Disorder
- What is being tested?
- Biological samples and Biological
- How many people
- 350 participants
- Where
- 1 siteFrance
- Study dates
- 16 Sep 2024to 16 Sep 2034
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Up to 99 years
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Patients with with growth plate or bone pathology.
Who may be able to join
- Children (from birth) with growth plate or bone pathology
- Patients affiliated to or benefiting from a social security scheme
- Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies :
- mastery of the French language
- Not being subject to a restriction of rights by the judicial authorities
- Patients or legal representatives having given their consent to participate in the study (expression of non-opposition).
Who cannot join
- Patients under legal protection (guardianship, curatorship or safeguard of justice)
- Pregnant or breast-feeding women
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
University Toulouse Hospital
Toulouse, 31000
Thomas EDOUARD, MD, 0534558555 ext. +33, edouard.t@chu-toulouse.fr
Thomas EDOUARD, MD
About this study
Official title: Creation of a Biological Collection to Study the Pathophysiology and Identify Predictive Factors for the Evolution of Bone, Calcium and Growth Plate Pathologies
The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies.
This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.
- Conditions
- Bone Disorder
- Being tested
- Biological samples, Biological
- Medical subject headings
- Bone Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Biological samplesOther
Blood and urine will be taken in larger quantity
BiologicalOther
Surgical residues may be preserved in the event of surgery carried out as part of the treatment.
| Study group | Role | What they receive |
|---|---|---|
| Patients suffering from growth plate or bone pathology | As part of their pathology, patients benefit from clinical monitoring and regular blood and urine tests. Receives: Other: Biological samples; Other: Biological |
What is being measured
The primary outcome is the main question the study is designed to answer.
Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies
Blood and urine sampling
Measured: Day 0 and through study completion, an average of 5 years
Secondary outcomes (1)
Identification of potential markers of disease progression based on new knowledge.
Measured: Day 0 and through study completion, an average of 5 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Jun 2024
- Study start16 Sep 2024
- Primary completion16 Sep 2034 (estimated)
- Study completion16 Sep 2034 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Bone DisorderStudies of the same condition, open and under way.
- More trials run by University Hospital, ToulouseThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 350 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Toulouse
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Thomas EDOUARD, MD, Principal investigator, University Hospital, Toulouse
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06444503
- Sponsor's protocol ID
- RC31/24/0214
- Acronym
- OSCAR
- Status last verified
- Jun 2026
- First submitted
- 30 May 2024
- Last updated
- 5 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Creation of a Biological Collection to Study the Pathophysiology and Identify Predictive Factors for the Evolution of Bone, Calcium and Growth Plate Pathologies
- ClinicalTrials.gov ID
- NCT06444503
- Acronym / sponsor ID
- OSCAR / RC31/24/0214
- Conditions
- Bone Disorder
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 350 participants (estimated)
- Lead sponsor
- University Hospital, ToulouseUniversity, hospital or other
- Study start
- 16 Sep 2024 (actual)
- Primary completion
- 16 Sep 2034 (estimated)
- Study completion
- 16 Sep 2034 (estimated)
- First posted
- 5 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies.
This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients suffering from growth plate or bone pathology | – | Other: Biological samples, Other: BiologicalAs part of their pathology, patients benefit from clinical monitoring and regular blood and urine tests. |
Who may qualify
- Ages
- Up to 99 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients with with growth plate or bone pathology.
Key inclusion criteria (6 listed)
- Children (from birth) with growth plate or bone pathology
- Patients affiliated to or benefiting from a social security scheme
- Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies :
- mastery of the French language
- Not being subject to a restriction of rights by the judicial authorities
Key exclusion criteria (2 listed)
- Patients under legal protection (guardianship, curatorship or safeguard of justice)
- Pregnant or breast-feeding women
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Biological samplesBlood and urine will be taken in larger quantity | Other | Patients suffering from growth plate or bone pathology |
| BiologicalSurgical residues may be preserved in the event of surgery carried out as part of the treatment. | Other | Patients suffering from growth plate or bone pathology |
Primary outcome
Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies
Time frame: Day 0 and through study completion, an average of 5 years
Blood and urine sampling
1 secondary outcome
Identification of potential markers of disease progression based on new knowledge.
Time frame: Day 0 and through study completion, an average of 5 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Thomas EDOUARD, MD principal investigator
University Hospital, Toulouse
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Bone Disorder, run by University Hospital, Toulouse at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 5 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Thomas EDOUARD, MD (0534558555 ext. +33, edouard.t@chu-toulouse.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies (time frame: Day 0 and through study completion, an average of 5 years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Jun 2026.