Research institution
University Hospital, Toulouse Clinical Trials
Studies where University Hospital, Toulouse is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 178Osteonecrosis of the Jaw
Leukocyte- and Platelet-Rich Fibrin in the Surgical Treatment of Medication-related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious side-effect of antiresorptive therapies used in the management of bone diseases, such as osteoporosis or bone metastases.
- Trial name
- PeRFOrMand (NCT06419010)
- Testing
- Surgery with the use of L-PRF, Standard surgery
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Toulouse
Schizophrenia Disorders
Cognitive Remediation Method Using Rhythmic, Vocal and Corporal Musical Learning for Schizophrenia
Schizophrenia, affecting 1% of the population, is a persistent disorder characterized by varied symptoms. Antipsychotic medications effectively address positive symptoms (delusions, hallucinations) and relapse but have limited…
- Trial name
- ARCoS-2 (NCT07055204)
- Testing
- "Diapason & Metronome" musical learning
- Where
- 6 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Toulouse
Cirrhosis
"Anticipant"-TIPS After a First Portal-hypertension-related Complication in Cirrhosis
Further decompensation (FD) in cirrhosis represents a prognostic stage associated with an even higher mortality than that associated with the first decompensation.
- Trial name
- Ant-TIPS (NCT07889726)
- Testing
- TIPS, Standard of Care (SOC)
- Where
- 8 sites in France
- Volunteers
- 266 people
- Sponsor
- University Hospital, Toulouse
Epilepsy
Contribution of Fast-ripples to the Improvement of the Neurosurgical Management of Drug-refractory Epilepsy
The main aim of this study is to evaluate the contribution of fast-ripples (FR) information on the neurosurgery management of patients with drug-refractory epilepsy investigated by Stereo-ElectroEncephaloGraphy (SEEG), as…
- Trial name
- NENUFAR (NCT06105645)
- Testing
- DIXI Medical Microdeep® Micro- Macro Depth electrodes, Standard electrodes
- Where
- 12 sites in France
- Volunteers
- 440 people
- Sponsor
- University Hospital, Toulouse
Severe Asthma
Withdrawal of Dupilumab in Severe Asthma
Asthma management has been revolutionised by the development of biological therapies. Dupilumab is an anti-interleukin4 receptor marketed in 2020 for severe asthmatic patients with 2 exacerbations or more within the last 12…
- Trial name
- WIDUSA (NCT06818019)
- Testing
- Stopping dupilumab
- Where
- 29 sites in France
- Volunteers
- 205 people
- Sponsor
- University Hospital, Toulouse
Pregnancy
Comparative Analysis of Labor Induction Using a Balloon Catheter at Home Versus in the Hospital
An increasing proportion of patients undergo labor induction at the end of pregnancy. Balloon induction at home is a method validated in the literature.
- Trial name
- BALHOME (NCT07848412)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
PARKINSON DISEASE (Disorder)
Effect of Botulinum Toxin on Resting Tremor of the Refractory Upper Limb in Parkinsonians
Tremor is one of the most common symptoms in Parkinson Disease (PD), affecting almost 60% of patients. There is currently no specific treatment for tremor in PD, and 30% of patients develop drug-resistant tremor, making its…
- Trial name
- TOX PARK (NCT07822893)
- Where
- 2 sites in France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Toulouse
Hearing Loss
Optimization of Hearing Performance in the Subject Implanted
In the past two decades, the selection criteria for cochlear implantation have been greatly relaxed so that about 60-70% of present cochlear implant (CI) candidates have significant residual hearing in their contralateral ear.
- Trial name
- OPERSA (NCT05325450)
- Testing
- Program A, Program B, Control
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Appetite Loss in Aging, Anorexia of Aging
Study on the Prevention of Weight Loss Through Physical Activity Among Nursing Home Residents
Appetite loss is frequent in institutionalized older adults. Physical activity is known for its benefits on appetite regulation but its effects in nursing home residents remain poorly investigated.
- Trial name
- EAT-PA (NCT07831733)
- Testing
- Physical activity, Appetite assessment, Food intake assessment
- Where
- France
- Volunteers
- 596 people
- Sponsor
- University Hospital, Toulouse
Cannabis Intoxication in Children
Contamination of Young Children Hair During Acute Cannabis Intoxication
Hair analysis in pediatric cannabis intoxication is limited by possible sudoral self-contamination, especially in young children due to hair porosity. However, adult studies show no THC-COOH in sweat, challenging this hypothesis.
- Trial name
- INTERACTION (NCT07524088)
- Testing
- sudoral and hairing sampling
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Toulouse
Completed, with results posted
All 2COVID-19
Efficacy of Pre-exposure Treatment With Hydroxy-Chloroquine on the Risk and Severity of COVID-19 Infection
There is a pandemic in the world by COVID-19. Currently, the pharmacological curative or prophylactic treatments for this infection are not known.
- Trial name
- PREPCOV (NCT04481633)
- Testing
- COVID 19 serology, COVID 19 Self-Questionnaire
- Where
- 12 sites in France
- Volunteers
- 547 people
- Sponsor
- University Hospital, Toulouse
Prader Willi Syndrome
Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS Infants
The Prader-Willi syndrome (PWS) includes severe neonatal hypotonia with impaired suckling leading to failure to thrive in the most severe cases, subsequently followed by an early onset of morbid obesity with hyperphagia and…
- Trial name
- OTBB2 (NCT02205034)
- Testing
- oxytocin
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse