Alveolar OsteitisNCT06481293
Tackling Dry Socket Via Laser Therapy in Smokers
A study testing Diode laser therapy and Alveogyl dressing in people with Alveolar Osteitis, run by Badr University at 1 site in Egypt.
Trial summary
This study examines the efficiency of diode laser therapy to manage dry sockets after tooth extraction. Read more about this study
- Who is it for?
- Ages 25 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Alveolar Osteitis
- What is being tested?
- Diode laser therapy and Alveogyl dressing
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteEgypt
- Study dates
- 30 Oct 2023to 20 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Smokers patient
Who cannot join
- Females on contraceptives.
- Diabetic patients
- Hepatitis C virus patients
- Patients on corticosteroids
- Patients with renal diseases
- Anemic patients
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Tackling Dry Socket Via Dual Wavelength Laser Diode Therapy in Smokers: A Randomized Controlled Trial.
This study examines the efficiency of diode laser therapy to manage dry sockets after tooth extraction.
Read the detailed description
The study compares the efficiency of diode laser therapy and using only alveogyl to accelerate the healing of dry sockets after tooth extraction in smokers. Smoker patients with dry sockets were enrolled randomly into two different groups. Group 1 received dual wavelength laser diode therapy, three times per week. While group 2 received only a topical application of alveogl. The treatment lasted for two consecutive weeks. The treatment efficiency was evaluated by measuring the volume of the socket using the syringe method. The pain level was measured by the visual analog scale.
- Conditions
- Alveolar Osteitis
- Being tested
- Diode laser therapy, Alveogyl dressing
- Keywords
- Diode laser, Dry socket
- Medical subject headings
- Dry Socket
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Diode laser therapyDevice
Dual wavelength laser diode therapy device
Alveogyl dressingCombination product
Alveogyl is a haemostatic-analgesic alveolar dressing
| Study group | Role | What they receive |
|---|---|---|
| Group 1 | Experimental | Group 1 received diode laser therapy Receives: Device: Diode laser therapy |
| group 2 | Experimental | Group 2 received topical application of aveogl dressing Receives: Combination Product: Alveogyl dressing |
What is being measured
The primary outcome is the main question the study is designed to answer.
Socket volume
measured through the volumetric measurement method using a syringe filled with saline
Measured: 2 weeks
Secondary outcomes (1)
Pain level
measured by the visual analogue scale(VAS). It include score from 0 to 10 in which 10 indicates the worst pain level and 0 indicates no pain
Measured: 2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jul 2024
- Study start30 Oct 2023
- Primary completion20 Sep 2024
- Study completion20 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alveolar OsteitisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The study included two groups. One group receives dual wavelength laser diode therapy and the other group receives topical aveogyl dressing.
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Badr University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Reham Alaa, Badr University
- Investigators
- reham Elkalla, lecturer, Principal investigator, Badr University in Cairo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06481293
- Sponsor's protocol ID
- BUC-IACUC-231015-42
- Status last verified
- Sep 2025
- First submitted
- 25 Jun 2024
- Last updated
- 25 Sep 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Tackling Dry Socket Via Dual Wavelength Laser Diode Therapy in Smokers: A Randomized Controlled Trial.
- ClinicalTrials.gov ID
- NCT06481293
- Acronym / sponsor ID
- BUC-IACUC-231015-42
- Conditions
- Alveolar Osteitis
- Keywords
- Diode laser, Dry socket
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Badr UniversityUniversity, hospital or other
- Study start
- 30 Oct 2023 (actual)
- Primary completion
- 20 Sep 2024 (actual)
- Study completion
- 20 Sep 2025 (actual)
- First posted
- 1 Jul 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study examines the efficiency of diode laser therapy to manage dry sockets after tooth extraction.
Detailed description
The study compares the efficiency of diode laser therapy and using only alveogyl to accelerate the healing of dry sockets after tooth extraction in smokers. Smoker patients with dry sockets were enrolled randomly into two different groups. Group 1 received dual wavelength laser diode therapy, three times per week. While group 2 received only a topical application of alveogl. The treatment lasted for two consecutive weeks. The treatment efficiency was evaluated by measuring the volume of the socket using the syringe method. The pain level was measured by the visual analog scale.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- The study included two groups. One group receives dual wavelength laser diode therapy and the other group receives topical aveogyl dressing.
| Arm | Type | Receives |
|---|---|---|
| Group 1 | Experimental | Device: Diode laser therapyGroup 1 received diode laser therapy |
| group 2 | Experimental | Combination Product: Alveogyl dressingGroup 2 received topical application of aveogl dressing |
Who may qualify
- Ages
- 25 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Smokers patient
Key exclusion criteria (6 listed)
- Females on contraceptives.
- Diabetic patients
- Hepatitis C virus patients
- Patients on corticosteroids
- Patients with renal diseases
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Diode laser therapyDual wavelength laser diode therapy device | Device | Group 1 |
| Alveogyl dressingAlveogyl is a haemostatic-analgesic alveolar dressing | Combination product | group 2 |
Primary outcome
Socket volume
Time frame: 2 weeks
measured through the volumetric measurement method using a syringe filled with saline
1 secondary outcome
Pain level
Time frame: 2 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Sep 2025.
- Individual participant dataSharing planned: No
Related trials for Alveolar Osteitis
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Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis
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Active, not recruiting
Alvogyl Versus Platelet-Rich Fibrin for Healing of Alveolar Osteitis
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Active, not recruiting
Chlorhexidine Versus Normal Saline Socket Irrigation for Prevention of Dry Socket After Lower Wisdom Tooth Extraction
Alveolar Osteitis, Impacted Lower Third Molar
Not yet recruiting
Effectiveness of Telephonic and Digital Postoperative Follow-up Communication Strategies on Patient Compliance, Clinical Recovery, and Quality of Life After Dental Extraction
Tooth Extraction, Postoperative Care
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
reham Elkalla, lecturer principal investigator
Badr University in Cairo
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Diode laser therapy and Alveogyl dressing in people with Alveolar Osteitis, run by Badr University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Socket volume (time frame: 2 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Sep 2025.