Knee ArthritisNCT06630052
Incidence of Tenderness Opposite to Adductor Canal in Patients Suffering From Osteoarthritis Knee Pain. A Cohort Study.
An observational study of Knee Arthritis, run by Cairo University at 2 sites in Egypt.
Trial summary
Knee osteoarthritis (KOA) is a common knee disorder. The pathological changes affecting the knee are typically examined by using X-ray imaging to assess the narrowing of the joint space and the presence of osteophytes. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Knee Arthritis
- What is being tested?
- adductor canal clinical examination
- How many people
- 100 participants
- Where
- 2 sitesEgypt
- Study dates
- 1 Jul 2023to 15 Sep 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: Adult patients with confirmed KOA by symptomatic (rated knee pain > four on a 10-point numeric rating pain scale (NRP scale)) and radiologically (Kellgren-Lawrence grades I, II ) findings
Who may be able to join
- Adult patients with confirmed KOA by symptomatic (rated knee pain > four on a 10-point numeric rating pain scale (NRP scale)) and radiologically (Kellgren-Lawrence grades I, II ) findings
Who cannot join
- Post-traumatic knee osteoarthritis, oncological diseases, endocrine diseases (gout, diabetes), autoimmune diseases (rheumatoid arthritis), infectious diseases and patients with a history of previous knee surgeries or endoscopies
Trial locations and contacts
2 sites in 1 country.
Egypt2 sites
Anesthesia department - Faculty of medicine- Cairo University
Cairo
Abeer Ahmed Mohamed
Maadi, Cairo Governorate, 11728
About this study
Knee osteoarthritis (KOA) is a common knee disorder. The pathological changes affecting the knee are typically examined by using X-ray imaging to assess the narrowing of the joint space and the presence of osteophytes. However, some previous clinical trials have revealed a discrepancy between the severity of joint pain and the image finding even with the use of knee MRI. Some studies have revealed that there are age-related changes in the type of fibers with the formation of a network of transverse fiber bands, and this may cause some compression or traction on the neurovascular content of the adductor canal. Other studies noted the presence of excessive yellow-colored adipose tissue that stretches or entangles some nerve fibers. The primary outcome of this study will be the incidence rate of tenderness over the midthigh corresponding to the AC in patients with KOA who are complaining of severe pain that is discordant with the radiological finding.
- Conditions
- Knee Arthritis
- Being tested
- adductor canal clinical examination
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
adductor canal clinical examinationOther
clinical examination of the adductor canal in patients with knee pain not matching the radiological changes
What is being measured
The primary outcome is the main question the study is designed to answer.
incidence of tenderness corresponding to the AC in patients complaining of severe pain with discordant with the radiological finding
the presence of tenderness by hand pressing over AC for 3-4 cm depth
Measured: time of clinical examination at the date of the visit to the pain clinic till the knee interventions up to 2 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Oct 2024
- Study start1 Jul 2023
- Primary completion15 Aug 2024
- Study completion15 Sep 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee ArthritisStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Abeer Ahmed, MD, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06630052
- Sponsor's protocol ID
- MS-310-2023
- Status last verified
- Oct 2024
- First submitted
- 31 Jan 2024
- Last updated
- 8 Oct 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 8 Oct 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Incidence of Tenderness Opposite to Adductor Canal in Patients Suffering From Osteoarthritis Knee Pain. A Cohort Study.
- ClinicalTrials.gov ID
- NCT06630052
- Acronym / sponsor ID
- MS-310-2023
- Conditions
- Knee Arthritis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jul 2023 (actual)
- Primary completion
- 15 Aug 2024 (actual)
- Study completion
- 15 Sep 2024 (actual)
- First posted
- 8 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Knee osteoarthritis (KOA) is a common knee disorder. The pathological changes affecting the knee are typically examined by using X-ray imaging to assess the narrowing of the joint space and the presence of osteophytes. However, some previous clinical trials have revealed a discrepancy between the severity of joint pain and the image finding even with the use of knee MRI. Some studies have revealed that there are age-related changes in the type of fibers with the formation of a network of transverse fiber bands, and this may cause some compression or traction on the neurovascular content of the adductor canal. Other studies noted the presence of excessive yellow-colored adipose tissue that stretches or entangles some nerve fibers. The primary outcome of this study will be the incidence rate of tenderness over the midthigh corresponding to the AC in patients with KOA who are complaining of severe pain that is discordant with the radiological finding.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- Adult patients with confirmed KOA by symptomatic (rated knee pain > four on a 10-point numeric rating pain scale (NRP scale)) and radiologically (Kellgren-Lawrence grades I, II ) findings
Key inclusion criteria (1 listed)
- Adult patients with confirmed KOA by symptomatic (rated knee pain > four on a 10-point numeric rating pain scale (NRP scale)) and radiologically (Kellgren-Lawrence grades I, II ) findings
Key exclusion criteria (1 listed)
- Post-traumatic knee osteoarthritis, oncological diseases, endocrine diseases (gout, diabetes), autoimmune diseases (rheumatoid arthritis), infectious diseases and patients with a history of previous knee surgeries or endoscopies
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| adductor canal clinical examinationclinical examination of the adductor canal in patients with knee pain not matching the radiological changes | Other | – |
Primary outcome
incidence of tenderness corresponding to the AC in patients complaining of severe pain with discordant with the radiological finding
Time frame: time of clinical examination at the date of the visit to the pain clinic till the knee interventions up to 2 days
the presence of tenderness by hand pressing over AC for 3-4 cm depth
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2024.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Knee Arthritis, run by Cairo University at 2 sites in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Oct 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
incidence of tenderness corresponding to the AC in patients complaining of severe pain with discordant with the radiological finding (time frame: time of clinical examination at the date of the visit to the pain clinic till the knee interventions up to 2 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2024.