Tooth WearNCT06665191
Prevalence of Tooth Wear and Its Association with Oral Health-related Quality of Life
An observational study of Tooth Wear and Attrition, run by Cairo University.
Trial summary
The aim of this study is to detect the prevalence of tooth wear (All forms of cumulative surface loss of mineralized tooth substance loss due to physical and chemico-mechanical process according to the definition of the European Organization for Caries Research (ORCA) and the International Cariology Research Group for… Read more about this study
- Who is it for?
- Ages 31 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Tooth Wear, Attrition, Erosion
- How many people
- 1,011 participants
- Where
- No sites listed yet
- Study dates
- Feb 2026to Nov 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 31 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Middle aged adult patient attending educational hospital for dental treatments free of charfge
Who may be able to join
- 1- Patients whose age between 31 to 45 years old. 2- Egyptian 3- Males \& Females 4- Provide informed consent 5- Ability to comprehend asked questions
Who cannot join
- 1- Patients under or over the selected age group 2- Patients using fixed orthodontic appliances, 3- Patients with special needs
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
omnia Abdellatif omnia Abdellatif Amin, MSC. degree contact
About this study
Official title: Prevalence of Tooth Wear, Predictive Risk Factors and Its Association with Oral Health-related Quality of Life Among Middle -aged Adult Patients Attending Dental Educational Hospital At Cairo University: Cross-sectional Study
The aim of this study is to detect the prevalence of tooth wear (All forms of cumulative surface loss of mineralized tooth substance loss due to physical and chemico-mechanical process according to the definition of the European Organization for Caries Research (ORCA) and the International Cariology Research Group for Dental Research (IADR) i.e.: attrition, erosion and abrasion) among middle aged adult patients attending educational hospital at the Faculty of Dentistry, Cairo University and to analyze the distribution of lesions by gender and age, frequency of acidic foods and drinks consumption, medicine usage, chewing habits, systemic diseases, tooth brushing habits, and family socio economic status. Moreover, to evaluate the quality of life among middle aged elderly patients in relation to existence of tooth wear.
The study focuses on middle-aged adult patients (31-45 years) attending the Faculty of Dentistry at Cairo University during 2025-2026. It is an analytical cross-sectional study aimed at assessing the prevalence and risk level of tooth wear using the Basic Erosive Wear Examination Index (BEWE). The BEWE categorizes tooth wear into four levels (0 = no wear, 3 = severe wear), and risk levels are determined by the cumulative score.
Primary outcome: the prevalence of tooth wear and associated risk levels. Secondary outcomes: identifying predictive risk factors and assessing the Oral Health Impact Profile (OHIP) for patients diagnosed with tooth wear. All participants will be examined, and those with a BEWE score above 0 will be considered affected. Risk levels will be stratified as no risk, low, medium, or high.
- Conditions
- Tooth Wear, Attrition, Erosion
- Being tested
- No Intervention: Observational study for prevalence of dental wear and its association with quality of life
- Keywords
- Tooth wear, attrition, BEWE, Basic erosive wear examination, quality of life
- Medical subject headings
- Tooth Wear
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No Intervention: Observational study for prevalence of dental wear and its association with quality of lifeOther
not applicable as it is an observational study testing the prevalence of dental wear in patients attending Cairo University
| Study group | Role | What they receive |
|---|---|---|
| Middle aged Adults NOT suffering from dental wear | Middle aged Adults NOT suffering from dental wear attending dental educational hospital in Cairo University | |
| Middle aged adults Suffering from dental wear | Middle aged adults Suffering from dental wear attending dental educational hospital in Cairo University Receives: Other: No Intervention: Observational study for prevalence of dental wear and its association with quality of life |
What is being measured
The primary outcome is the main question the study is designed to answer.
Prevalence and risk level of tooth wear
Prevalence of wear will be tested using Basic erosive wear examination index (BEWE) 0 =no tooth wear
- =minimal loss of surface texture
- = distinct defect, hard tissue loss <50% of the surface area
- = hard tissue loss ≥ 50% of the surface area The examination is repeated for all teeth in a sextant but only the surface with the highest score is recorded for each sextant.
To calculate prevalence Examined participants with score 0 will represent unaffected population % Examined participants with scores above 0 will represent the affected population % Stratification of risk levels will be done for affected population according to BEWE risk levels. The sum of the scores is calculated to provide the BEWE risk level (0-14) 0-2 = no risk 3-8= low risk 9-13= medium risk 14= high risk
Measured: 1 year
Secondary outcomes (2)
• Predictive risk factors for all participants using a questionnaire
Sociodemographic data:
age, gender, occupation and education
Predictive risk factors:
- Frequency of consuming acidic food and fruits, carbonated beverages and alcohol.
- Medicine usage ( vitamin c, aspirin)
- Chewing habits
- Systemic diseases
- Tooth brushing habits
- Family socio economic status.
Measured: 1year
Oral Health-Related Quality of Life (OHRQoL) using a questionnaire
OHRQoL will be measured using Oral Health Index Profile (OHIP-14) questionnaire
OHIP-14 is a 14-item questionnaire that measures :
Functional limitation Physical pain Phycological discomfort Physical disability Social disability Phycological disability Handicap
It measures responses on a Likert scale (0-4) with the following values:
Never (0) Hardly ever (1) Occasionally (2) Frequently (3) Very frequently (4) Points for each response are summed so that each patient can score a minimum of 0 points and a maximum of 56 points. Low scores indicate better self-perceived quality of life, and high scores indicate worse self-perception of oral quality of life Participants diagnosed with tooth wear
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Oct 2024
- Study startFeb 2026 (estimated)
- Primary completionOct 2026 (estimated)
- Study completionNov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth WearStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Ecologic or community
- Time perspective
- Cross-sectional
- Enrolment
- 1,011 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Omnia Abdel-Latif Amin, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06665191
- Sponsor's protocol ID
- 1441991
- Status last verified
- Oct 2024
- First submitted
- 9 Oct 2024
- Last updated
- 30 Oct 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 30 Oct 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prevalence of Tooth Wear, Predictive Risk Factors and Its Association with Oral Health-related Quality of Life Among Middle -aged Adult Patients Attending Dental Educational Hospital At Cairo University: Cross-sectional Study
- ClinicalTrials.gov ID
- NCT06665191
- Acronym / sponsor ID
- 1441991
- Conditions
- Tooth Wear, Attrition, Erosion
- Keywords
- Tooth wear, attrition, BEWE, Basic erosive wear examination, quality of life
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 1,011 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- Feb 2026 (estimated)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Nov 2026 (estimated)
- First posted
- 30 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to detect the prevalence of tooth wear (All forms of cumulative surface loss of mineralized tooth substance loss due to physical and chemico-mechanical process according to the definition of the European Organization for Caries Research (ORCA) and the International Cariology Research Group for Dental Research (IADR) i.e.: attrition, erosion and abrasion) among middle aged adult patients attending educational hospital at the Faculty of Dentistry, Cairo University and to analyze the distribution of lesions by gender and age, frequency of acidic foods and drinks consumption, medicine usage, chewing habits, systemic diseases, tooth brushing habits, and family socio economic status. Moreover, to evaluate the quality of life among middle aged elderly patients in relation to existence of tooth wear.
The study focuses on middle-aged adult patients (31-45 years) attending the Faculty of Dentistry at Cairo University during 2025-2026. It is an analytical cross-sectional study aimed at assessing the prevalence and risk level of tooth wear using the Basic Erosive Wear Examination Index (BEWE). The BEWE categorizes tooth wear into four levels (0 = no wear, 3 = severe wear), and risk levels are determined by the cumulative score.
Primary outcome: the prevalence of tooth wear and associated risk levels. Secondary outcomes: identifying predictive risk factors and assessing the Oral Health Impact Profile (OHIP) for patients diagnosed with tooth wear. All participants will be examined, and those with a BEWE score above 0 will be considered affected. Risk levels will be stratified as no risk, low, medium, or high.
Study design
- Observational model
- Ecologic or community
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Middle aged Adults NOT suffering from dental wear | – | –Middle aged Adults NOT suffering from dental wear attending dental educational hospital in Cairo University |
| Middle aged adults Suffering from dental wear | – | Other: No Intervention: Observational study for prevalence of dental wear and its association with quality of lifeMiddle aged adults Suffering from dental wear attending dental educational hospital in Cairo University |
Who may qualify
- Ages
- 31 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Middle aged adult patient attending educational hospital for dental treatments free of charfge
Key inclusion criteria (1 listed)
- 1- Patients whose age between 31 to 45 years old. 2- Egyptian 3- Males \& Females 4- Provide informed consent 5- Ability to comprehend asked questions
Key exclusion criteria (1 listed)
- 1- Patients under or over the selected age group 2- Patients using fixed orthodontic appliances, 3- Patients with special needs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No Intervention: Observational study for prevalence of dental wear and its association with quality of lifenot applicable as it is an observational study testing the prevalence of dental wear in patients attending Cairo University | Other | Middle aged adults Suffering from dental wear |
Primary outcome
Prevalence and risk level of tooth wear
Time frame: 1 year
Prevalence of wear will be tested using Basic erosive wear examination index (BEWE) 0 =no tooth wear 1. =minimal loss of surface texture 2. = distinct defect, hard tissue loss <50% of the surface area 3. = hard tissue loss ≥ 50% of the surface area The examination is repeated for all teeth in a sextant but only the surface with the highest score is recorded for each sextant. To calculate prevalence Examined participants with score 0 will represent unaffected population % Examined participants with scores above 0 will represent the affected population % Stratification of risk levels will be done for affected population according to BEWE risk levels. The sum of the scores is calculated to provide the BEWE risk level (0-14) 0-2 = no risk 3-8= low risk 9-13= medium risk 14= high risk
2 secondary outcomes
• Predictive risk factors for all participants using a questionnaire
Time frame: 1year
Oral Health-Related Quality of Life (OHRQoL) using a questionnaire
Time frame: 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Oct 2024.
- Individual participant dataSharing planned: Undecided
Related trials for Tooth Wear
Active, not recruitingPhase 3
New In Situ Model Design for Caries and Erosion
Caries, Erosive Tooth Wear
Not yet recruiting
Applying Navigation and Care to Help Ongoing Retention
Child Obesity
Not yet recruitingObservational study
Salivary Function and Dental Changes During GLP-1 Therapy
Obesity, Dental Erosion
Not yet recruiting
Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth
Wear, Occlusal
Not yet recruiting
PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures
Edentulism Complete, Edentulism
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
omnia Abdellatif omnia Abdellatif Amin, MSC. degree contact
Questions about this trial
What is this clinical trial studying?
An observational study of Tooth Wear and Attrition, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 30 Oct 2024. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact omnia Abdellatif omnia Abdellatif Amin, MSC. degree (+2 01272512839, omnia.abdellatif@dentistry.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Prevalence and risk level of tooth wear (time frame: 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Oct 2024.