Healthy AgingNCT06718699
Accuracy of Prediction Equations to Calculate Maximum Strength
An observational study of Healthy Aging, run by University of Erlangen-Nürnberg Medical School at 1 site in Germany.
Trial summary
Resistance exercise training (RT) is a key component of health related exercise programs. However, an accurate specification of RT load prescription is essential for effective and safe achievement of training aims. Read more about this study
- Who is it for?
- Ages 18 to 85 years
- Conditions the study is for
- Healthy Aging
- What is being tested?
- resistance exercise tests
- How many people
- 120 participants
- Where
- 1 siteGermany
- Study dates
- 2 Dec 2024to 30 Sep 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The study population consists of resistance trained and untrained women and men 18 to 35 or 60-85 years old that are able to complete 1RM and RTF tests without endangering their health
Who may be able to join
- 18 to 35 years old
- 60 to 85 years old
Who cannot join
- Contraindication for one repetition maximum tests
- musculoskeletal injuries that may prevent a reliable and safe assessment of the 1RM and RTF tests
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Germany1 site
Institute of Radiology, University Hospital NErlangen
Erlangen, 91054
About this study
Official title: Accuracy of a New Prediction Equation to Calculate One Repetition Maximum (1RM) in Trained and Untrained Young and Old Adults
Resistance exercise training (RT) is a key component of health related exercise programs. However, an accurate specification of RT load prescription is essential for effective and safe achievement of training aims. Proper specification of exercise intensity might be the most critical issue when designing RT protocols for adults. One repetition maximum tests (1RM) have been considered the "gold standard" of dynamic maximum strength evaluation. Although the argument of increased risk of injuries and adverse effects with 1RM testing in older people has been rejected by several studies , limited motivation to lift maximum loads, requirement for high test effort, time constraints, and interruption of the continuity of the training process aggravate the frequent application of 1RM tests particularly in non-athletic RT. 1RM prediction equations that use the load and number of repetitions completed to fatigue (RTF) to predict repetition maximum might be a reliable and feasible option to 1RM testing. Thus, the primary aims of this study were to evaluate the predictive accuracy of current RTF equations and to develop an equation that more accurately predicts 1RM from RTF tests.
- Conditions
- Healthy Aging
- Being tested
- resistance exercise tests
- Keywords
- maximum strength, one repetition maximum, repetitions to fatigue, prediction equation, resistance exercise
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
resistance exercise testsOther
One 1RM and three RTF tests (5-8RM, 9-12RM, 13-16RM) on seven resistance training devices
What is being measured
The primary outcome is the main question the study is designed to answer.
Maximum load, one repetition maximum, leg press
Maximum load lifted once (1RM, in kg) for the leg press exercise
Measured: At baseline - no follow up tests
Secondary outcomes (27)
Maximum load lifted at 5-8RM, leg press
Maximum load lifted 5-8 times (RFT5-8, in kg) for the leg press exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 9-12RM, leg press
Maximum load lifted 5-8 times (RFT9-12, in kg) for the leg press exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, leg press
Maximum load lifted 5-8 times (RFT13-16, in kg) for the leg press exercise
Measured: At baseline - no follow up tests
Maximum load, one repetition maximum, lat pulls
Maximum load lifted once (1RM, in kg) for the latissimus pull exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, lat pulls
Maximum load lifted 5-8 times (RFT5-8, in kg) for the latissimus pull exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, lat pulls
Maximum load lifted 9-12 times (RFT9-12, in kg) for the latissimus pull exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, lat pulls
Maximum load lifted 13-16 times (RFT13-16, in kg) for the latissimus pull exercise
Measured: At baseline - no follow up tests
Maximum load, one repetition maximum, triceps dips
Maximum load lifted once (1RM, in kg) for the triceps dips exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, triceps dips
Maximum load lifted 5-8 times (RFT5-8, in kg) for the triceps dips exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, triceps dips
Maximum load lifted 9-12 times (RFT9-12, in kg) for the triceps dips exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, triceps dips
Maximum load lifted 13-16 times (RFT13-16, in kg) for the triceps dips exercise
Measured: At baseline - no follow up tests
Maximum load, one repetition maximum, trunk extension
Maximum load lifted once (1RM, in kg) for the trunk extension exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, trunk extension
Maximum load lifted 5-8 times (RFT5-8, in kg) for the trunk extension exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, trunk extension
Maximum load lifted 9-12 times (RFT9-12, in kg) for the trunk extension exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, trunk extension
Maximum load lifted 13-16 times (RFT13-16, in kg) for the trunk extension exercise
Measured: At baseline - no follow up tests
Maximum load, one repetition maximum, trunk flexion
Maximum load lifted once (1RM, in kg) for the trunk flexion exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, trunk flexion
Maximum load lifted 5-8 times (RFT5-8, in kg) for the trunk flexion exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, trunk flexion
Maximum load lifted 9-12 times (RFT9-12, in kg) for the trunk flexion exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, trunk flexion
Maximum load lifted 13-16 times (RFT13-16, in kg) for the trunk flexion exercise
Measured: At baseline - no follow up tests
Maximum load, one repetition maximum, leg flexion
Maximum load lifted once (1RM, in kg) for the leg flexion exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, leg flexion
Maximum load lifted 5-8 times (RFT5-8, in kg) for the leg flexion exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, leg flexion
Maximum load lifted 9-12 times (RFT9-12, in kg) for the leg flexion exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, leg flexion
Maximum load lifted 13-16 times (RFT13-16, in kg) for the leg flexion exercise
Measured: At baseline - no follow up tests
Maximum load, one repetition maximum, leg extension
Maximum load lifted once (1RM, in kg) for the leg extension exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, leg extension
Maximum load lifted 5-8 times (RFT5-8, in kg) for the leg extension exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, leg extension
Maximum load lifted 9-12 times (RFT9-12, in kg) for the leg extension exercise
Measured: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, leg extension
Maximum load lifted 13-16 times (RFT13-16, in kg) for the leg extension exercise
Measured: At baseline - no follow up tests
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Dec 2024
- Study start2 Dec 2024
- Primary completion31 Aug 2026 (estimated)
- Study completion30 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy AgingStudies of the same condition, open and under way.
- More trials run by University of Erlangen-Nürnberg Medical SchoolThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Erlangen-Nürnberg Medical School
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Wolfgang Kemmler, PhD, University of Erlangen-Nürnberg Medical School
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06718699
- Sponsor's protocol ID
- PREDEQ
- Other IDs
- Physiomed ID 101
- Status last verified
- Jan 2026
- First submitted
- 1 Dec 2024
- Last updated
- 29 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Accuracy of a New Prediction Equation to Calculate One Repetition Maximum (1RM) in Trained and Untrained Young and Old Adults
- ClinicalTrials.gov ID
- NCT06718699
- Acronym / sponsor ID
- PREDEQ
- Conditions
- Healthy Aging
- Keywords
- maximum strength, one repetition maximum, repetitions to fatigue, prediction equation, resistance exercise
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- University of Erlangen-Nürnberg Medical SchoolUniversity, hospital or other
- Study start
- 2 Dec 2024 (actual)
- Primary completion
- 31 Aug 2026 (estimated)
- Study completion
- 30 Sep 2026 (estimated)
- First posted
- 5 Dec 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Resistance exercise training (RT) is a key component of health related exercise programs. However, an accurate specification of RT load prescription is essential for effective and safe achievement of training aims. Proper specification of exercise intensity might be the most critical issue when designing RT protocols for adults. One repetition maximum tests (1RM) have been considered the "gold standard" of dynamic maximum strength evaluation. Although the argument of increased risk of injuries and adverse effects with 1RM testing in older people has been rejected by several studies , limited motivation to lift maximum loads, requirement for high test effort, time constraints, and interruption of the continuity of the training process aggravate the frequent application of 1RM tests particularly in non-athletic RT. 1RM prediction equations that use the load and number of repetitions completed to fatigue (RTF) to predict repetition maximum might be a reliable and feasible option to 1RM testing. Thus, the primary aims of this study were to evaluate the predictive accuracy of current RTF equations and to develop an equation that more accurately predicts 1RM from RTF tests.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The study population consists of resistance trained and untrained women and men 18 to 35 or 60-85 years old that are able to complete 1RM and RTF tests without endangering their health
Key inclusion criteria (2 listed)
- 18 to 35 years old
- 60 to 85 years old
Key exclusion criteria (2 listed)
- Contraindication for one repetition maximum tests
- musculoskeletal injuries that may prevent a reliable and safe assessment of the 1RM and RTF tests
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| resistance exercise testsOne 1RM and three RTF tests (5-8RM, 9-12RM, 13-16RM) on seven resistance training devices | Other | – |
Primary outcome
Maximum load, one repetition maximum, leg press
Time frame: At baseline - no follow up tests
Maximum load lifted once (1RM, in kg) for the leg press exercise
27 secondary outcomes
Maximum load lifted at 5-8RM, leg press
Time frame: At baseline - no follow up tests
Maximum load lifted at 9-12RM, leg press
Time frame: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, leg press
Time frame: At baseline - no follow up tests
Maximum load, one repetition maximum, lat pulls
Time frame: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, lat pulls
Time frame: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, lat pulls
Time frame: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, lat pulls
Time frame: At baseline - no follow up tests
Maximum load, one repetition maximum, triceps dips
Time frame: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, triceps dips
Time frame: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, triceps dips
Time frame: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, triceps dips
Time frame: At baseline - no follow up tests
Maximum load, one repetition maximum, trunk extension
Time frame: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, trunk extension
Time frame: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, trunk extension
Time frame: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, trunk extension
Time frame: At baseline - no follow up tests
Maximum load, one repetition maximum, trunk flexion
Time frame: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, trunk flexion
Time frame: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, trunk flexion
Time frame: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, trunk flexion
Time frame: At baseline - no follow up tests
Maximum load, one repetition maximum, leg flexion
Time frame: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, leg flexion
Time frame: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, leg flexion
Time frame: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, leg flexion
Time frame: At baseline - no follow up tests
Maximum load, one repetition maximum, leg extension
Time frame: At baseline - no follow up tests
Maximum load lifted at 5-8 RM, leg extension
Time frame: At baseline - no follow up tests
Maximum load lifted at 9-12 RM, leg extension
Time frame: At baseline - no follow up tests
Maximum load lifted at 13-16 RM, leg extension
Time frame: At baseline - no follow up tests
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Healthy Aging, run by University of Erlangen-Nürnberg Medical School at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 29 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Maximum load, one repetition maximum, leg press (time frame: At baseline - no follow up tests). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jan 2026.