Rejection SensitivityNCT06777823
Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls
A study testing Social Rejection Task in people with Rejection Sensitivity and Puberty, run by Washington University School of Medicine at 1 site in United States.
Trial summary
This longitudinal study is designed to test bidirectional relationships between preteen girls' mental health and social media experiences. We will explore how pubertal development and experiences of rejection influence these relationships. Read more about this study
- Who is it for?
- Ages 10 years and older, women onlyHealthy volunteers can take part
- Conditions the study is for
- Rejection Sensitivity, Puberty, Psychopathology
- What is being tested?
- Social Rejection Task
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 250 participants
- Where
- 1 siteUnited States
- Study dates
- 5 Feb 2025to 30 Jun 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 years and older
- Women only
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- female aged 10-11 years
- engagement in social media use
- proficient in the English language
- family/personal device that can complete daily diaries
Who cannot join
- previously diagnosed chronic medical illness
- autism spectrum disorder
- significant developmental or speech delay
- endocrine disorder
- not assigned female at birth (AFAB)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Washington University School of Medicine
St Louis, Missouri, 63110
Hailey
About this study
This longitudinal study is designed to test bidirectional relationships between preteen girls' mental health and social media experiences. We will explore how pubertal development and experiences of rejection influence these relationships.
- Conditions
- Rejection Sensitivity, Puberty, Psychopathology
- Being tested
- Social Rejection Task
- Keywords
- puberty, rejection sensitivity, psychopathology, social media
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Social Rejection TaskBehavioural
All participants will receive this
| Study group | Role | What they receive |
|---|---|---|
| All participants | Experimental | All participants complete the study intervention Receives: Behavioral: Social Rejection Task |
What is being measured
The primary outcome is the main question the study is designed to answer.
Psychopathology symptoms parent report
Measured via the KSADS interview
Measured: "Through study completion, an average of two years"
Psychopathology symptoms child report
Measured via the KSADS interview
Measured: "Through study completion, an average of two years"
Daily Diary Social Media experiences
Assessed through daily diary reports (e.g., 'Did you use social media today?")
Measured: Through study completion, an average of two years
MicroEMA Social Media experiences
Assessed through microEMA prompt (e.g., 'using Social Media?")
Measured: Through study completion, an average of two years
Social Media experiences child report
Assessed through a screen time questionnaire
Measured: Through study completion, an average of two years
Social Media experiences parent report
Assessed through a screen time questionnaire
Measured: Through study completion, an average of two years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jan 2025
- Study start5 Feb 2025
- Primary completion1 Jun 2028 (estimated)
- Study completion30 Jun 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Rejection SensitivityStudies of the same condition, open and under way.
- More trials run by Washington University School of MedicineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 250 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Washington University School of Medicine
- Sponsor type
- University, hospital or other
- Collaborators
- St. Louis University, Northeastern University
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06777823
- Sponsor's protocol ID
- 1R01MH135480-01A1-202407113
- Other IDs
- 1R01MH135480-01A1
- Status last verified
- Apr 2026
- First submitted
- 30 Dec 2024
- Last updated
- 6 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 6 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls
- ClinicalTrials.gov ID
- NCT06777823
- Acronym / sponsor ID
- 1R01MH135480-01A1-202407113
- Conditions
- Rejection Sensitivity, Puberty, Psychopathology
- Keywords
- puberty, rejection sensitivity, psychopathology, social media
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 250 participants (estimated)
- Lead sponsor
- Washington University School of MedicineUniversity, hospital or other
- Collaborators
- St. Louis University, Northeastern University
- Study start
- 5 Feb 2025 (actual)
- Primary completion
- 1 Jun 2028 (estimated)
- Study completion
- 30 Jun 2029 (estimated)
- First posted
- 16 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This longitudinal study is designed to test bidirectional relationships between preteen girls' mental health and social media experiences. We will explore how pubertal development and experiences of rejection influence these relationships.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| All participants | Experimental | Behavioral: Social Rejection TaskAll participants complete the study intervention |
Who may qualify
- Ages
- 10 years and older
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (4 listed)
- female aged 10-11 years
- engagement in social media use
- proficient in the English language
- family/personal device that can complete daily diaries
Key exclusion criteria (5 listed)
- previously diagnosed chronic medical illness
- autism spectrum disorder
- significant developmental or speech delay
- endocrine disorder
- not assigned female at birth (AFAB)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Social Rejection TaskAll participants will receive this | Behavioural | All participants |
Primary outcome
Psychopathology symptoms parent report
Time frame: "Through study completion, an average of two years"
Measured via the KSADS interview
Psychopathology symptoms child report
Time frame: "Through study completion, an average of two years"
Measured via the KSADS interview
Daily Diary Social Media experiences
Time frame: Through study completion, an average of two years
Assessed through daily diary reports (e.g., 'Did you use social media today?")
MicroEMA Social Media experiences
Time frame: Through study completion, an average of two years
Assessed through microEMA prompt (e.g., 'using Social Media?")
Social Media experiences child report
Time frame: Through study completion, an average of two years
Assessed through a screen time questionnaire
Social Media experiences parent report
Time frame: Through study completion, an average of two years
Assessed through a screen time questionnaire
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 May 2026.
- Individual participant dataSharing planned: Yes
Related trials for Rejection Sensitivity
Active, not recruiting
Role of Adverse Childhood Events and Rejection Sensitivity on Alcohol Use in Recently Withdrawn Individuals With Alcohol Use Disorder
Alcohol-Induced Disorders, Ostracism
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Social Rejection Task in people with Rejection Sensitivity and Puberty, run by Washington University School of Medicine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hailey Hatch, PhD (314-273-7288, hatchh@wustl.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Psychopathology symptoms parent report (time frame: "Through study completion, an average of two years"). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 May 2026.