Clinical trials: Psychopathology
Drug Use, Drug Abuse
Acute Intervention to Reduce Distress Following Sexual Assault
The purpose of this study was to evaluate whether a brief intervention in video format delivered in the post assault medical exam setting and including education about assault reactions and instruction in and modeling of…
- Conditions
- Drug Use, Drug Abuse, Posttraumatic Stress Disorder
- Trial name
- NCT01622855
- Testing
- PPRS
- Where
- United States
- Volunteers
- 442 people
- Sponsor
- Medical University of South Carolina
Clozapine Resistant Schizophrenia
Maintenance Electroconvulsive Therapy (ECT) Versus Aripiprazole in Clozapine-resistant Schizophrenia
The pharmacological treatment options in schizophrenia developing resistance to clozapine are limited. Few studies have found ECT as beneficial in TRS, including CRS.
- Trial name
- NCT06501339
- Testing
- maintenance ECT, Aripiprazole tablet
- Volunteers
- 40 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Depression, Pregnancy
Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development --- How is Paternal Psychopathology Involved?
This study aims at investigating the effects of maternal depressive symptomatology on pregnancy outcomes and newborn development. How paternal psychopathology is involved in the association will also be explored.
- Trial name
- NCT01280474
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Treatment Resistant Schizophrenia
Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia
The proposed study will be conducted to compare the efficacy of maintenance ECT (M-ECT) vs Clozapine in treatment resistant schizophrenia (TRS) in terms of change in psychopathology measures and cerebral hemodynamics.
- Trial name
- NCT03807882
- Testing
- Bilateral M-ECT, Clozapine
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Socioemotional Development, Cognitive Ability
Early Institutionalization Intervention Impact Project
The purpose of this study is to determine the effects of early intervention (placement into foster care, and a caregiving training) on physical, cognitive, social and brain development and psychiatric symptomatology in children…
- Conditions
- Socioemotional Development, Cognitive Ability, Behavioral and Neural Patterns of Attention, Brain Function
- Trial name
- EI-3 (NCT04165746)
- Testing
- Foster Care, Caregiving Intervention
- Where
- Brazil
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Stress, Anxiety
ACT for HIV-Positive Men
The purpose of the current study is to examine the feasibility and effectiveness of acceptance and commitment therapy, a specific form of cognitive-behavioral therapy, for treating general mental health concerns among…
- Conditions
- Stress, Anxiety, Mental Disorder, Distress-based Psychopathology
- Trial name
- ACT for HIV (NCT06625437)
- Testing
- Acceptance and commitment therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Alabama at Birmingham
Scoliosis
HRQoL and Function of Adults Treated in Adolescence for Scoliosis With Physical Exercises
We attempt to investigate the influence of physiotherapy and physical activity education applied in adolescence on physical fitness, curve progression, pulmonary function, physical activity and quality of life in adulthood.
- Trial name
- NCT01384955
- Where
- Poland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Schizophrenia and Schizoaffective Disorder
Relationship Between Physical Fitness and Psychopathology, Cognition and Quality of Life in Patients Diagnosed With Schizophrenia: a Mixed Method Study.
The goal of this observational study is to assess the physical fitness and the influence of possible factors (disease symptomatology, cognitive status, patient functioning and degree of perceived quality of life) on patients…
- Trial name
- COFESQ (NCT06824584)
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Universidade da Coruña
Binge Eating Disorder, Obesity
Effectiveness of Cognitive Behavioral Therapy Plus Nutritional Counseling in Promoting Weight Loss in People With Binge Eating Disorder
This study will evaluate the effectiveness of adding nutritional counseling to cognitive behavioral therapy in treating obese people with binge eating disorder.
- Conditions
- Binge Eating Disorder, Obesity, Overweight
- Trial name
- NCT00601653
- Testing
- Cognitive behavioral therapy plus general nutrition counseling (CBT+GN), Cognitive behavioral therapy plus low energy density diet counseling (CBT+LED)
- Volunteers
- 50 people
- Sponsor
- Yale University
Borderline Personality Disorder
Personality Change Study for Borderline Personality Disorder
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment.
- Trial name
- NCT06005129
- Testing
- Personality-Based Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Maternal Depression, Self-Regulation, Emotion
Building Regulation in Dual Generations 2022-2025
This randomized control trial aims to investigate whether a novel intervention, the "Building Regulation in Dual Generations (BRIDGE)" program, improves mental wellness and parenting practices among mothers of 3 to 5-year-old…
- Conditions
- Maternal Depression, Self-Regulation, Emotion, Child Mental Disorder, Child Development
- Trial name
- BRIDGE (NCT05959538)
- Testing
- Building Regulation in Dual Generations (BRIDGE), Dialectical Behavioural Therapy Skill Training
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Schizophrenia, Major Depression
Effect of Specific Anti-Toxoplasmatic Add-on Medication in Toxoplasma Gondii Seropositive Individuals With Schizophrenia or Major Depression
We investigate whether the add-on specific antitoxoplasmatic medication has positive effects in individuals with schizophrenia or major depression seropositive for Toxoplasma gondii (TG) infection.
- Trial name
- NCT00300404
- Testing
- daraprim, pyrimethamine, folinic acid
- Volunteers
- 40 people
- Sponsor
- Zentrum für Integrative Psychiatrie
Psychopathology
Can Applying the Science of Habit Formation to Contemplative Practice Improve Outcomes
In the present study, the investigators will conduct a confirmatory efficacy trial to test whether improving practice automaticity (i.e., habit formation) of self-compassionate touch improves outcomes in the predicted direction.
- Trial name
- NCT05866718
- Testing
- Self-Compassionate Touch Intervention, Habit Formation Tools
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Delivery; Trauma, Covid19
Delivery During Covid-19 Pandemic: Implications for Obstetrics, Maternal Psychopathology, and Mother-Infant Relationship
The Coronavirus 2019 (COVID-19) pandemic has brought about unprecedented social, economic and mental-health challenges, especially for vulnerable populations such as pregnant and post-partum females.
- Trial name
- NCT04609501
- Where
- Israel
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Hypopituitarism, Central Diabetes Insipidus
Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)
Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function.
- Conditions
- Hypopituitarism, Central Diabetes Insipidus, Panhypopituitarism, Psychological Disorder
- Trial name
- NCT04897802
- Testing
- Experimental: GLP1-RA (exenatide) administration
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Child Development
Examining the Role of Pain in the Link Between Early Childhood Adversity and Psychopathology
The goal of this study is to investigate the role of physical pain in the link between childhood adversity and later psychopathology.
- Trial name
- NCT06445712
- Testing
- Parental Support Cold Pressor Task
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Washington University School of Medicine
Anxiety, Suicide
Computerized Anxiety Treatment for Suicide
The purpose of this study is to test the effectiveness and usability of multiple computer-based treatments for mood and anxiety relevant risk factors.
- Trial name
- CATS (NCT01990131)
- Testing
- Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Florida State University
Emotional Disorder
Unified Protocol for Emotional Disorders: HiTOP-PRO Trial
This randomised, parallel-group clinical trial evaluates the effects of the Unified Protocol (UP), a transdiagnostic cognitive-behavioural psychotherapy, on dimensional symptom outcomes aligned with the Hierarchical Taxonomy of…
- Trial name
- UP-HITOP (NCT07557017)
- Testing
- Unified Protocol, Treatment as usual (TAU)
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- National Institute of Mental Health, Czech Republic
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Insomnia, Delayed Sleep Phase Disorder
Blue-blocking Glasses for Sleep Disorders in Child and Adolescent Psychiatry
Sleep problems and regulation difficulties are frequent in the child and adolescent psychiatry population. Insomnia and delayed sleep-wake phase disorders (DSPWD) are highly prevalent, and risk factors for developing more severe…
- Conditions
- Insomnia, Delayed Sleep Phase Disorder, Hyperarousal, Transdiagnostic Psychopathology
- Trial name
- BATCAT-pilot (NCT07433491)
- Testing
- Blue-blocking glasses (BB-glasses) or real darkness from 9 p.m. to desired wake-up time + night mode setting on mobile phone, Control
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Fonna