Dental WearNCT06807125
Wear Measurement of Opposing Enamel to Milled Resin Matrix Ceramic Versus Bulk Fill Resin Composite After 2 Years
A study testing Resin matrix ceramic block in people with Dental Wear, run by Misr University for Science and Technology at 1 site in Egypt.
Trial summary
This clinical trial conducted to measure the amount of wear of opposing enamel to indirect milled resin matrix ceramic versus direct bulk fill resin composite intraorally using Digital Scanner after two years of using Read more about this study
- Who is it for?
- Ages 18 to 55 yearsHealthy volunteers can take part
- Conditions the study is for
- Dental Wear
- What is being tested?
- Resin matrix ceramic block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 26 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Jan 2023to 10 Jan 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- ● Patients with non vital badly decayed posterior teeth.
- 18 -55years.
- Males or Females.
- Good oral hygiene.
- Co-operative patients approving to participate in the study
Who cannot join
- High caries index.
- Severe medical complications.
- Pregnancy.
- Allergic history concerning methacrylates Disabilities.
- Heavy smoking.
- Xerostomia.
Show all 9Show fewer
- Lack of compliance.
- Evidence of parafunctional habits.
- Temporomandibular joint disorders.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Intraoral Wear Measurement of Opposing Enamel to Indirect Milled Resin Matrix Ceramic Versus Direct Bulk Fill Resin Composite in Posterior Teeth After Using 2 Years: Randomized Clinical Trial
This clinical trial conducted to measure the amount of wear of opposing enamel to indirect milled resin matrix ceramic versus direct bulk fill resin composite intraorally using Digital Scanner after two years of using
Read the detailed description
Indirect milled resin matrix ceramic overlay versus direct bulk fill resin composite overlay was utilized in a clinical trial to compare the amount of enamel wear on endodontically treated molars using a Panda P2 digital scanner and Geomagic Control X 3D software. After one and two years, measurements of enamel wear were taken.
- Conditions
- Dental Wear
- Being tested
- Resin matrix ceramic block
- Keywords
- Wear measurements, resin matrix ceramic, Bulk fill composite, Digital scanner.
- Medical subject headings
- Tooth Wear
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resin matrix ceramic blockProcedure or surgery
Also called CAD/CAM Reinforced composite overlay
Milled resin composite block for fabrication of permanent, indirect restorations using a CAD/CAM grinding process. shock absorbing affect due to the dentin- like modulus of elasticity makes BRILLIANT Crios will suited or indirect restoration.
| Study group | Role | What they receive |
|---|---|---|
| Resin matrix ceramic block | Experimental | BRILLIANT Crios is the ideal choice for single-tooth restorations, both in the anterior and the posterior region. It is composed of dental glass (barium glass ˂ 1.0 μm), amorphous silica (Sio2 ˂ 20 nm), resin matrix (cross-linked methacrylates) and pigments (inorganic pigments such as ferrous oxide or titanium dioxide). Receives: Procedure: Resin matrix ceramic block |
| Direct Restoration | Active comparator | 3M™ Filtek™ One Bulk Fill Restorative is a visible light activated, restorative composite optimized to create fast and easy restorations. The material can be placed and cured up to 5 mm deep, enabled by a stress relieving resin system and optimized optical properties. It is composed of fillers which are a combination of a non-agglomerated/non-aggregated 20 nm silica filler.
4 to 11 nm zirconia filler, zirconia/silica cluster filler and ytterbium trifluoride filler consisting of 100nm particles. The inorganic filler loading is about 76.5% by weight (58.5% by volume). It contains AFM (dynamic stress-relieving monomer), AUDMA, UDMA and 1, 12-dodecane-DMA. 3M™ Filtek™ Bulk Fill Posterior Restorative is applied to the tooth following use of a methacrylate-based dental adhesive Receives: Procedure: Resin matrix ceramic block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Amount of Enamel Wear
amount of enamel wear measured through superimposition of STL files exported from intraoral scanner then using geomagic Control X 3D
Measured: two years follow up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Feb 2025
- Study start10 Jan 2023
- Primary completion10 Jan 2024
- Study completion10 Jan 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Dental WearStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized Clinical Trial
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 26 participants (actual)
Sponsor and investigators
- Lead sponsor
- Misr University for Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Esraa Esmeail Hussien, Misr University for Science and Technology
- Investigators
- Esraa EE Hussien, PhD, Principal investigator, Misr University for Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06807125
- Sponsor's protocol ID
- 2024-0063
- Status last verified
- Jan 2025
- First submitted
- 29 Jan 2025
- Last updated
- 4 Feb 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Elhaddad EEH, Elkady AAM, Diab DFS. A two year randomized clinical trial comparing opposing enamel wear from milled resin-matrix ceramic and direct bulk-fill composite overlays. BDJ Open. 2026 Feb 21;12(1):19. doi: 10.1038/s41405-026-00400-9.
PubMed 41723141
Study at a glance
From the registry record, last updated by the sponsor on 4 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Intraoral Wear Measurement of Opposing Enamel to Indirect Milled Resin Matrix Ceramic Versus Direct Bulk Fill Resin Composite in Posterior Teeth After Using 2 Years: Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT06807125
- Acronym / sponsor ID
- 2024-0063
- Conditions
- Dental Wear
- Keywords
- Wear measurements, resin matrix ceramic, Bulk fill composite, Digital scanner.
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 26 participants (actual)
- Lead sponsor
- Misr University for Science and TechnologyUniversity, hospital or other
- Study start
- 10 Jan 2023 (actual)
- Primary completion
- 10 Jan 2024 (actual)
- Study completion
- 10 Jan 2025 (actual)
- First posted
- 4 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This clinical trial conducted to measure the amount of wear of opposing enamel to indirect milled resin matrix ceramic versus direct bulk fill resin composite intraorally using Digital Scanner after two years of using
Detailed description
Indirect milled resin matrix ceramic overlay versus direct bulk fill resin composite overlay was utilized in a clinical trial to compare the amount of enamel wear on endodontically treated molars using a Panda P2 digital scanner and Geomagic Control X 3D software. After one and two years, measurements of enamel wear were taken.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- Randomized Clinical Trial
| Arm | Type | Receives |
|---|---|---|
| Resin matrix ceramic block | Experimental | Procedure: Resin matrix ceramic blockBRILLIANT Crios is the ideal choice for single-tooth restorations, both in the anterior and the posterior region. It is composed of dental glass (barium glass ˂ 1.0 μm), amorphous silica (Sio2 ˂ 20 nm), resin matrix (cross-linked methacrylates) and pigments (inorganic pigments such as ferrous oxide or titanium dioxide). |
| Direct Restoration | Active comparator | Procedure: Resin matrix ceramic block3M™ Filtek™ One Bulk Fill Restorative is a visible light activated, restorative composite optimized to create fast and easy restorations. The material can be placed and cured up to 5 mm deep, enabled by a stress relieving resin system and optimized optical properties. It is composed of fillers which are a combination of a non-agglomerated/non-aggregated 20 nm silica filler. 4 to 11 nm zirconia filler, zirconia/silica cluster filler and ytterbium trifluoride filler consisting of 100nm particles. The inorganic filler loading is about 76.5% by weight (58.5% by volume). It contains AFM (dynamic stress-relieving monomer), AUDMA, UDMA and 1, 12-dodecane-DMA. 3M™ Filtek™ Bulk Fill Posterior Restorative is applied to the tooth following use of a methacrylate-based dental adhesive |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- ● Patients with non vital badly decayed posterior teeth.
Key exclusion criteria (9 listed)
- High caries index.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Resin matrix ceramic blockAlso: CAD/CAM Reinforced composite overlayMilled resin composite block for fabrication of permanent, indirect restorations using a CAD/CAM grinding process. shock absorbing affect due to the dentin- like modulus of elasticity makes BRILLIANT Crios will suited or indirect restoration. | Procedure or surgery | Direct Restoration, Resin matrix ceramic block |
Primary outcome
Amount of Enamel Wear
Time frame: two years follow up
amount of enamel wear measured through superimposition of STL files exported from intraoral scanner then using geomagic Control X 3D
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Feb 2025.
- Derived from this study: PubMed 41723141Elhaddad EEH, Elkady AAM, Diab DFS. A two year randomized clinical trial comparing opposing enamel wear from milled resin-matrix ceramic and direct bulk-fill composite overlays. BDJ Open. 2026 Feb 21;12(1):19. doi: 10.1038/s41405-026-00400-9.
- Individual participant dataSharing planned: No
Related trials for Dental Wear
Active, not recruitingPhase 3
New In Situ Model Design for Caries and Erosion
Caries, Erosive Tooth Wear
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Applying Navigation and Care to Help Ongoing Retention
Child Obesity
Not yet recruitingObservational study
Salivary Function and Dental Changes During GLP-1 Therapy
Obesity, Dental Erosion
Not yet recruiting
Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth
Wear, Occlusal
Not yet recruiting
PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures
Edentulism Complete, Edentulism
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Esraa EE Hussien, PhD principal investigator
Misr University for Science and Technology
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Resin matrix ceramic block in people with Dental Wear, run by Misr University for Science and Technology at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Amount of Enamel Wear (time frame: two years follow up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06807125, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Feb 2025.