Anaerobic PerformanceBFR-TrainingNCT06822595
High-Load Blood Flow Restriction (BFR) Training May Decrease Anaerobic Fatigue in Distance Runners
A study testing Blood flow restriction (BFR) training and Isokinetic training in people with Anaerobic Performance, run by Gulhane Training and Research Hospital at 2 sites in Turkey (Türkiye).
Trial summary
This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners. To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners. Read more about this study
- Who is it for?
- Ages 22 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Anaerobic Performance
- What is being tested?
- Blood flow restriction (BFR) training and Isokinetic training
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 2 sitesTurkey (Türkiye)
- Study dates
- 15 Jul 2022to 15 Jul 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 22 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- The absence of cardiovascular or musculoskeletal conditions,
- No recent resistance training,
- Running more than 20 kilometers per week.
Who cannot join
- Having a cardiovascular or musculoskeletal condition,
- Having done recent resistance training,
- Running less than 20 kilometers per week.
Trial locations and contacts
2 sites in 1 country.
Turkey (Türkiye)2 sites
Hüseyin Günaydın
Ankara, 06018
University of Health Sciences, Gulhane Faculty of Medicine
Ankara, 06018
About this study
Official title: High-Load Blood Flow Restriction (BFR) Training May Decrease Anaerobic Fatigue in Distance Runners: A Randomized Controlled Trial
This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners. To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners. Forty-two runners were randomized into BFR (n=21) and control (n=21) groups. Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Anaerobic performance was assessed via the Wingate test, and 5 km and 10 km running times were recorded before and after the intervention. Statistical analyses compared pre- and post-training performance within and between groups.
Read the detailed description
Blood flow restriction (BFR) training is increasingly used to enhance athletic performance, but its effects on anaerobic fatigue in distance runners remain unclear. This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners.To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners.
Forty-two runners were randomized into BFR (n=21) and control (n=21) groups. Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Anaerobic performance was assessed via the Wingate test, and 5 km and 10 km running times were recorded before and after the intervention. Statistical analyses compared pre- and post-training performance within and between groups.
- Conditions
- Anaerobic Performance
- Being tested
- Blood flow restriction (BFR) training, Isokinetic training
- Keywords
- Athlete, muscular, KAATSU, sports medicine, performance
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Blood flow restriction (BFR) trainingDevice
Also called Isokinetic training
Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure.
Isokinetic trainingDevice
Both groups followed an identical 8-week isokinetic training protocol twice weekly.
| Study group | Role | What they receive |
|---|---|---|
| Blood flow restriction (BFR) Group | Experimental | BFR group followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Receives: Device: Blood flow restriction (BFR) training; Device: Isokinetic training |
| Control Group | Active comparator | Control group followed an identical 8-week isokinetic training protocol twice weekly. Receives: Device: Isokinetic training |
What is being measured
The primary outcome is the main question the study is designed to answer.
The effects of an isokinetic training program combined with blood flow restriction (BFR) on anaerobic performance and fatigue resistance in long-distance runners were investigated.
Lower extremity Wingate Test (WanT) was used to evaluate the anaerobic capacities of long-distance runners. In calculating the fatigue index; (peak power - minimum power/peak power) x 100 (% fatigue index) formula was used.
Measured: baseline and week 8
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Feb 2025
- Study start15 Jul 2022
- Primary completion15 May 2023
- Study completion15 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anaerobic PerformanceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 42 participants (actual)
Sponsor and investigators
- Lead sponsor
- Gulhane Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Tuğba Kocahan, Gulhane Training and Research Hospital
- Investigators
- Hüseyin Günaydın, Study chair, University of Health Sciences, Gulhane Faculty of Medicine, Ankara/Türkiye
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06822595
- Sponsor's protocol ID
- SBU-GTF
- Acronym
- BFR-Training
- Status last verified
- Feb 2025
- First submitted
- 2 Feb 2025
- Last updated
- 12 Feb 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- High-Load Blood Flow Restriction (BFR) Training May Decrease Anaerobic Fatigue in Distance Runners: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06822595
- Acronym / sponsor ID
- BFR-Training / SBU-GTF
- Conditions
- Anaerobic Performance
- Keywords
- Athlete, muscular, KAATSU, sports medicine, performance
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 42 participants (actual)
- Lead sponsor
- Gulhane Training and Research HospitalOther government
- Study start
- 15 Jul 2022 (actual)
- Primary completion
- 15 May 2023 (actual)
- Study completion
- 15 Jul 2024 (actual)
- First posted
- 12 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners. To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners. Forty-two runners were randomized into BFR (n=21) and control (n=21) groups. Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Anaerobic performance was assessed via the Wingate test, and 5 km and 10 km running times were recorded before and after the intervention. Statistical analyses compared pre- and post-training performance within and between groups.
Detailed description
Blood flow restriction (BFR) training is increasingly used to enhance athletic performance, but its effects on anaerobic fatigue in distance runners remain unclear. This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners.To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners.
Forty-two runners were randomized into BFR (n=21) and control (n=21) groups. Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Anaerobic performance was assessed via the Wingate test, and 5 km and 10 km running times were recorded before and after the intervention. Statistical analyses compared pre- and post-training performance within and between groups.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Blood flow restriction (BFR) Group | Experimental | Device: Blood flow restriction (BFR) training, Device: Isokinetic trainingBFR group followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. |
| Control Group | Active comparator | Device: Isokinetic trainingControl group followed an identical 8-week isokinetic training protocol twice weekly. |
Who may qualify
- Ages
- 22 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- The absence of cardiovascular or musculoskeletal conditions,
- No recent resistance training,
- Running more than 20 kilometers per week.
Key exclusion criteria (3 listed)
- Having a cardiovascular or musculoskeletal condition,
- Having done recent resistance training,
- Running less than 20 kilometers per week.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Blood flow restriction (BFR) trainingAlso: Isokinetic trainingBoth groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. | Device | Blood flow restriction (BFR) Group |
| Isokinetic trainingBoth groups followed an identical 8-week isokinetic training protocol twice weekly. | Device | Blood flow restriction (BFR) Group, Control Group |
Primary outcome
The effects of an isokinetic training program combined with blood flow restriction (BFR) on anaerobic performance and fatigue resistance in long-distance runners were investigated.
Time frame: baseline and week 8
Lower extremity Wingate Test (WanT) was used to evaluate the anaerobic capacities of long-distance runners. In calculating the fatigue index; (peak power - minimum power/peak power) x 100 (% fatigue index) formula was used.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Feb 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hüseyin Günaydın study chair
University of Health Sciences, Gulhane Faculty of Medicine, Ankara/Türkiye
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Blood flow restriction (BFR) training and Isokinetic training in people with Anaerobic Performance, run by Gulhane Training and Research Hospital at 2 sites in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The effects of an isokinetic training program combined with blood flow restriction (BFR) on anaerobic performance and fatigue resistance in long-distance runners were investigated. (time frame: baseline and week 8). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Feb 2025.