PRESSURE PAIN THRESHOLDNCT06836193
Do Emotions Affect Mechanical Pain Thresholds in Individuals with Chronic Pain?
A study testing Emotional intervention in people with PRESSURE PAIN THRESHOLD, run by Linnaeus University.
Trial summary
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds in individuals with chronic pain. Read more about this study
- Who is it for?
- Ages 19 years and older
- Conditions the study is for
- PRESSURE PAIN THRESHOLD
- What is being tested?
- Emotional intervention
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 152 participants
- Where
- No sites listed yet
- Study dates
- 1 Jan 2026to 31 Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Above 18 years of age
- Fluent in Swedish
- Persistent chronic pain with duration > 6 months Exclusion criteria
- Known neurological disease
Who cannot join
None listed.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds in individuals with chronic pain.
Read the detailed description
Participants will be randomized into 4 different groups watching different short video-clips (2.20 min). The negative emotions group will watch an uncomfortable short video containing violence and blood, the positive emotions group will watch a video containing a stand-up comedy show, the neutral emotions group will watch a video about how to paint a house, and the control group will just wait for 2.20 min, without any instructions about what to think about. Pressure pain thresholds will be measured with an algometer before and after the video-clips.
- Conditions
- PRESSURE PAIN THRESHOLD
- Being tested
- Emotional intervention
- Keywords
- Pressure Pain Threshold, Pain, Emotion
- Medical subject headings
- Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Emotional interventionOther
Negative emotional intervention
Emotional interventionOther
Positive emotional intervention
| Study group | Role | What they receive |
|---|---|---|
| Negative emotional condition | Experimental | The participant will watch a short video-clip with negative emotional content. Receives: Other: Emotional intervention |
| Positive emotional condition | Experimental | The participant will watch a short video-clip with positive emotional content. Receives: Other: Emotional intervention |
| Neutral emotional condition | Sham comparator | The participant will watch a short video-clip with neutral emotional content. Receives: Other: Emotional intervention |
| No emotional condition | Sham comparator | The participant will wait for 2.30 minutes without any instructions about how to engage their thoughts. Receives: Other: Emotional intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pressure pain thresholds will be measured in kPa
Pressure pain thresholds will be measured in kPa using a handheld algometer (Somedic AB).
Measured: The measurement takes place at the intervention session. First a baseline measurement is conducted, then comes the intervention and then the intervention measurement takes place.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Feb 2025
- Study start1 Jan 2026 (estimated)
- Primary completionJun 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PRESSURE PAIN THRESHOLDStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 152 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Linnaeus University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Helena Gunnarsson, Linnaeus University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06836193
- Sponsor's protocol ID
- Dnr 2024-07781-01
- Status last verified
- Feb 2025
- First submitted
- 12 Feb 2025
- Last updated
- 20 Feb 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 20 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain
- ClinicalTrials.gov ID
- NCT06836193
- Acronym / sponsor ID
- Dnr 2024-07781-01
- Conditions
- PRESSURE PAIN THRESHOLD
- Keywords
- Pressure Pain Threshold, Pain, Emotion
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 152 participants (estimated)
- Lead sponsor
- Linnaeus UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (estimated)
- Primary completion
- Jun 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 20 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds in individuals with chronic pain.
Detailed description
Participants will be randomized into 4 different groups watching different short video-clips (2.20 min). The negative emotions group will watch an uncomfortable short video containing violence and blood, the positive emotions group will watch a video containing a stand-up comedy show, the neutral emotions group will watch a video about how to paint a house, and the control group will just wait for 2.20 min, without any instructions about what to think about. Pressure pain thresholds will be measured with an algometer before and after the video-clips.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Negative emotional condition | Experimental | Other: Emotional interventionThe participant will watch a short video-clip with negative emotional content. |
| Positive emotional condition | Experimental | Other: Emotional interventionThe participant will watch a short video-clip with positive emotional content. |
| Neutral emotional condition | Sham comparator | Other: Emotional interventionThe participant will watch a short video-clip with neutral emotional content. |
| No emotional condition | Sham comparator | Other: Emotional interventionThe participant will wait for 2.30 minutes without any instructions about how to engage their thoughts. |
Who may qualify
- Ages
- 19 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Above 18 years of age
- Fluent in Swedish
- Persistent chronic pain with duration > 6 months Exclusion criteria
- Known neurological disease
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Emotional interventionNegative emotional intervention | Other | Negative emotional condition, Neutral emotional condition |
| Emotional interventionPositive emotional intervention | Other | No emotional condition, Positive emotional condition |
Primary outcome
Pressure pain thresholds will be measured in kPa
Time frame: The measurement takes place at the intervention session. First a baseline measurement is conducted, then comes the intervention and then the intervention measurement takes place.
Pressure pain thresholds will be measured in kPa using a handheld algometer (Somedic AB).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Feb 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Emotional intervention in people with PRESSURE PAIN THRESHOLD, run by Linnaeus University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 20 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Helena Gunnarsson, Dr (+46708432509, helena.gunnarsson@lnu.se), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pressure pain thresholds will be measured in kPa (time frame: The measurement takes place at the intervention session. First a baseline measurement is conducted, then comes the intervention and then the intervention measurement takes place.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Feb 2025.