Nutritional InterventionCALMNCT06852547
The Effect of Ingesting a Novel Algae Protein Source on Rested and Exercised Muscle Protein Synthesis Rates in Older Adults.
A study testing protein in people with Nutritional Intervention, run by University of Exeter at 1 site in United Kingdom.
Trial summary
To assess the rested and postexercise muscle protein synthetic response following the ingestion of a flavourless algae protein source compared with whey protein in older adults. Read more about this study
- Who is it for?
- Ages 65 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Nutritional Intervention
- What is being tested?
- protein
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 15 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 23 Feb 2025to 1 Mar 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 80 years
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- Males and Females BMI 18.5 - 30 kg/m2 Aged 65-80 years Recreationally Active
Who cannot join
- Body mass index (BMI) <18.5 or >30 kg/m2 Any metabolic impairments Any cardiovascular impairments High blood pressure (≥140/90 mmHg) Any gastrointestinal disorders Any medications known to affect protein and/or amino acid metabolism A personal or family history of epilepsy, seizures or schizophrenia, motor disorder Chronic over the counter use of pharmaceuticals (> 1 month) Allergic to any of the whole foods included in the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United Kingdom1 site, 1 recruiting
- Recruiting
Health and Life Sciences
Exeter, EX2 8BD
Freyja A.D Haigh, PhD, 07917608163, fh357@exeter.ac.uk
About this study
Official title: Ingestion of a Novel Algae Protein Source on Rested and Post Exercise Muscle Protein Synthesis Rates.
To assess the rested and postexercise muscle protein synthetic response following the ingestion of a flavourless algae protein source compared with whey protein in older adults.
- Conditions
- Nutritional Intervention
- Being tested
- protein
- Keywords
- novel protein, protein synthesis, older adults, alge
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
proteinDietary supplement
Also called algae protein
protein
| Study group | Role | What they receive |
|---|---|---|
| Whey protein | Active comparator | Not described Receives: Dietary Supplement: protein |
| Algae protein | Experimental | Not described Receives: Dietary Supplement: protein |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postprandial muscle protein synthesis
unilateral exercise followed by protein ingestion (algae / whey)
Measured: 4 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Feb 2025
- Study start23 Feb 2025
- Primary completion1 Dec 2025 (estimated)
- Study completion1 Mar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nutritional InterventionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 15 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Exeter
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Freyja Haigh, University of Exeter
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06852547
- Sponsor's protocol ID
- 9071916
- Acronym
- CALM
- Status last verified
- Feb 2025
- First submitted
- 24 Feb 2025
- Last updated
- 28 Feb 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Ingestion of a Novel Algae Protein Source on Rested and Post Exercise Muscle Protein Synthesis Rates.
- ClinicalTrials.gov ID
- NCT06852547
- Acronym / sponsor ID
- CALM / 9071916
- Conditions
- Nutritional Intervention
- Keywords
- novel protein, protein synthesis, older adults, alge
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- University of ExeterUniversity, hospital or other
- Study start
- 23 Feb 2025 (actual)
- Primary completion
- 1 Dec 2025 (estimated)
- Study completion
- 1 Mar 2026 (estimated)
- First posted
- 28 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To assess the rested and postexercise muscle protein synthetic response following the ingestion of a flavourless algae protein source compared with whey protein in older adults.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Whey protein | Active comparator | Dietary Supplement: protein |
| Algae protein | Experimental | Dietary Supplement: protein |
Who may qualify
- Ages
- 65 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (1 listed)
- Males and Females BMI 18.5 - 30 kg/m2 Aged 65-80 years Recreationally Active
Key exclusion criteria (1 listed)
- Body mass index (BMI) <18.5 or >30 kg/m2 Any metabolic impairments Any cardiovascular impairments High blood pressure (≥140/90 mmHg) Any gastrointestinal disorders Any medications known to affect protein and/or amino acid metabolism A personal or family history of epilepsy, seizures or schizophrenia, motor disorder Chronic over the counter use of pharmaceuticals (> 1 month) Allergic to any of the whole foods included in the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| proteinAlso: algae proteinprotein | Dietary supplement | Algae protein, Whey protein |
Primary outcome
Postprandial muscle protein synthesis
Time frame: 4 hours
unilateral exercise followed by protein ingestion (algae / whey)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Feb 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing protein in people with Nutritional Intervention, run by University of Exeter at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Freyja A.D Haigh, PhD (+447917608163, fh357@exeter.ac.uk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postprandial muscle protein synthesis (time frame: 4 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Feb 2025.