Older AdultsNCT06901700
Effects of Home-based Lower Extremity Muscle Power Training on Functional Muscle and Balance Performance in Older Adults
A study testing Experimental Group in people with Older Adults, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.
Trial summary
Background: Muscle power, defined as the rate at which muscular force is generated to produce movement, declines more rapidly with age than muscle strength. The decline in lower extremity muscle power is associated with reduced functional independence, impaired mobility, and an increased risk of falls among older… Read more about this study
- Who is it for?
- Ages 65 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Older Adults
- What is being tested?
- Experimental Group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteTaiwan
- Study dates
- 16 Jul 2025to 30 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 80 years
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- 65~80 years old community-dwelling adults
- MMSE≥24
- Use smart phone routinely
Who cannot join
- Recent (<1 year) musculoskeletal injury or disability in the lower limbs
- Unstable cardiovascular, neurological disease, or metabolic disease interfering with participating in the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
National Yang Ming Chiao Tung University
Taipei, 112
Ray-Yau Wang, PhD, +886-2-28267210, rywang@nycu.edu.tw
About this study
Background: Muscle power, defined as the rate at which muscular force is generated to produce movement, declines more rapidly with age than muscle strength. The decline in lower extremity muscle power is associated with reduced functional independence, impaired mobility, and an increased risk of falls among older adults. While power training has been shown to improve muscle power, balance, and functional abilities, the feasibility and effectiveness of home-based interventions have not been thoroughly investigated.
Purpose: The aim of this study is to investigate the effects of home-based lower extremity muscle power training program on functional muscle and balance performance in older adults.
Read more
Methods: This is a single-blind, randomized controlled trial. Forty community-dwelling older adults will be recruited and randomly assigned to the experimental group (n=20) and control group (n=20). Participants in the experimental group will complete 24 sessions of home-based lower extremity muscle power training targeting the lower limb muscle groups in 8 weeks. The training intensity will be progressively adjusted according to participants' performance. Participants in the control group will maintain their daily activities. In addition, both groups will receive health education. Primary outcomes include functional muscle power measured by the Four-Step Stair Climb Power Test, functional muscle strength measured by Five Times Sit-to-Stand Test, and the functional balance performance measured by the Mini-BESTest, and Timed Up and Go Test. The fall confidence, as the secondary outcome, will be measured by Falls Efficacy Scale International.
Statistical analysis: The SPSS® version 29 will be used for statistical analysis. Independent-t-test or chi-square test will be conducted to compare the baseline demographic characteristics between groups. Two-way repeated measure ANOVA will be used to compare the differences between groups and times, post-hoc analyses will be performed using Tukey's test. The significance level is set at 0.05.
- Conditions
- Older Adults
- Being tested
- Experimental Group, control group
- Keywords
- Power training, Home-based training, Muscle performance, Balance, Older adults
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Experimental GroupOther
Total 40~60 minutes, 3 sessions per week in alternate day for 8 weeks, total 24 sessions 5 min warm up and 5 min cool down Power training (using body weight as resistance): hip flexor, hip extensor, hip adductor, hip abductor, knee flexor, ankle plantarflexor, hip external rotator, hip internal rotator, knee extensor, ankle dorsiflexor, ankle invertor, ankle evertor
control groupOther
Health education
| Study group | Role | What they receive |
|---|---|---|
| Control group | Other | Health education Receives: Other: control group |
| Experimental group | Experimental | Total 40~60 minutes, 3 sessions per week in alternate day for 8 weeks, total 24 sessions Receives: Other: Experimental Group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Functional muscle performance-muscle power
The Four-Step Stair Climb Power Test is used for measurement, where participants rapidly ascend four steps while the required time is recorded. This test is designed to assess lower limb muscle power.
Measured: From baseline to the end of treatment at 8 weeks
Functional muscle performance-muscle strength
The 5 Times Sit-to-Stand Test is used for measurement, where participants quickly and continuously perform five sit-to-stand movements while the required time is recorded. This test is designed to assess lower limb muscle strength.
Measured: From baseline to the end of treatment at 8 weeks
Balance
The Mini-BESTest (Balance Evaluation Systems Test) is used for measurement. This test includes anticipatory control, reactive postural control, sensory orientation, and dynamic gait, allowing for the assessment of balance abilities related to postural control.
Measured: From baseline to the end of treatment at 8 weeks
Timed Up and Go Test
The Timed Up and Go (TUG) Test is conducted at both a normal and fast pace to assess the balance and mobility of community-dwelling older adults in functional activities.
Measured: From baseline to the end of treatment at 8 weeks
Secondary outcomes (1)
Fall confidence
The Falls Efficacy Scale International (FES-I) is used for assessment. This scale evaluates the level of confidence in not falling while performing activities of daily living.
Measured: From baseline to the end of treatment at 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Mar 2025
- Study start16 Jul 2025
- Primary completion30 Apr 2026 (estimated)
- Study completion30 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Older AdultsStudies of the same condition, open and under way.
- More trials run by National Yang Ming Chiao Tung UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Yang Ming Chiao Tung University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Ray-Yau Wang, PhD, Principal investigator, National Yang Ming Chiao Tung University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06901700
- Sponsor's protocol ID
- NYCU114046AF
- Status last verified
- Mar 2025
- First submitted
- 24 Mar 2025
- Last updated
- 5 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Home-based Lower Extremity Muscle Power Training on Functional Muscle and Balance Performance in Older Adults
- ClinicalTrials.gov ID
- NCT06901700
- Acronym / sponsor ID
- NYCU114046AF
- Conditions
- Older Adults
- Keywords
- Power training, Home-based training, Muscle performance, Balance, Older adults
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- National Yang Ming Chiao Tung UniversityUniversity, hospital or other
- Study start
- 16 Jul 2025 (actual)
- Primary completion
- 30 Apr 2026 (estimated)
- Study completion
- 30 Apr 2026 (estimated)
- First posted
- 30 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background: Muscle power, defined as the rate at which muscular force is generated to produce movement, declines more rapidly with age than muscle strength. The decline in lower extremity muscle power is associated with reduced functional independence, impaired mobility, and an increased risk of falls among older adults. While power training has been shown to improve muscle power, balance, and functional abilities, the feasibility and effectiveness of home-based interventions have not been thoroughly investigated.
Purpose: The aim of this study is to investigate the effects of home-based lower extremity muscle power training program on functional muscle and balance performance in older adults.
Methods: This is a single-blind, randomized controlled trial. Forty community-dwelling older adults will be recruited and randomly assigned to the experimental group (n=20) and control group (n=20). Participants in the experimental group will complete 24 sessions of home-based lower extremity muscle power training targeting the lower limb muscle groups in 8 weeks. The training intensity will be progressively adjusted according to participants' performance. Participants in the control group will maintain their daily activities. In addition, both groups will receive health education. Primary outcomes include functional muscle power measured by the Four-Step Stair Climb Power Test, functional muscle strength measured by Five Times Sit-to-Stand Test, and the functional balance performance measured by the Mini-BESTest, and Timed Up and Go Test. The fall confidence, as the secondary outcome, will be measured by Falls Efficacy Scale International.
Statistical analysis: The SPSS® version 29 will be used for statistical analysis. Independent-t-test or chi-square test will be conducted to compare the baseline demographic characteristics between groups. Two-way repeated measure ANOVA will be used to compare the differences between groups and times, post-hoc analyses will be performed using Tukey's test. The significance level is set at 0.05.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control group | Other | Other: control groupHealth education |
| Experimental group | Experimental | Other: Experimental GroupTotal 40~60 minutes, 3 sessions per week in alternate day for 8 weeks, total 24 sessions |
Who may qualify
- Ages
- 65 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (3 listed)
- 65~80 years old community-dwelling adults
- MMSE≥24
- Use smart phone routinely
Key exclusion criteria (2 listed)
- Recent (<1 year) musculoskeletal injury or disability in the lower limbs
- Unstable cardiovascular, neurological disease, or metabolic disease interfering with participating in the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Experimental GroupTotal 40~60 minutes, 3 sessions per week in alternate day for 8 weeks, total 24 sessions 5 min warm up and 5 min cool down Power training (using body weight as resistance): hip flexor, hip extensor, hip adductor, hip abductor, knee flexor, ankle plantarflexor, hip external rotator, hip internal rotator, knee extensor, ankle dorsiflexor, ankle invertor, ankle evertor | Other | Experimental group |
| control groupHealth education | Other | Control group |
Primary outcome
Functional muscle performance-muscle power
Time frame: From baseline to the end of treatment at 8 weeks
The Four-Step Stair Climb Power Test is used for measurement, where participants rapidly ascend four steps while the required time is recorded. This test is designed to assess lower limb muscle power.
Functional muscle performance-muscle strength
Time frame: From baseline to the end of treatment at 8 weeks
The 5 Times Sit-to-Stand Test is used for measurement, where participants quickly and continuously perform five sit-to-stand movements while the required time is recorded. This test is designed to assess lower limb muscle strength.
Balance
Time frame: From baseline to the end of treatment at 8 weeks
The Mini-BESTest (Balance Evaluation Systems Test) is used for measurement. This test includes anticipatory control, reactive postural control, sensory orientation, and dynamic gait, allowing for the assessment of balance abilities related to postural control.
Timed Up and Go Test
Time frame: From baseline to the end of treatment at 8 weeks
The Timed Up and Go (TUG) Test is conducted at both a normal and fast pace to assess the balance and mobility of community-dwelling older adults in functional activities.
1 secondary outcome
Fall confidence
Time frame: From baseline to the end of treatment at 8 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Sep 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ray-Yau Wang, PhD principal investigator
National Yang Ming Chiao Tung University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Experimental Group in people with Older Adults, run by National Yang Ming Chiao Tung University at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 5 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ray-Yau Wang, PhD (+88628267210, rywang@nycu.edu.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Functional muscle performance-muscle power (time frame: From baseline to the end of treatment at 8 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Sep 2025.