Clinical trials: Older Adults
Outcomes Following Major Surgery in Older Adults
The Irish Perioperative OutcomeS (IPOS) Study
The Irish Perioperative OutcomeS (IPOS) Study aims to better understand the factors that influence recovery and outcomes in older adults undergoing major surgery in Ireland.
- Trial name
- IPOS (NCT07895199)
- Volunteers
- 500 people
- Sponsor
- University College Hospital Galway
Frailty/Sarcopenia, Frailty in Older Adults
Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From the Municipality of Santoña: a Quasi-experimental Study.
This study evaluates the effects of a community-based multicomponent exercise program on physical function, frailty, and sarcopenia in older adults living in the municipality of Santoña (Cantabria, Spain).
- Conditions
- Frailty/Sarcopenia, Frailty in Older Adults, Sarcopenia
- Trial name
- NCT07732478
- Testing
- Multicomponent Exercise Program (Vivifrail-based)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Universidad de Granada
Older Adults (60 - 85 Years Old), Self-care
Acceptance-based Self-care Intervention for Older Adults With Multimorbidity
The proposed 27-month three-arm parallel, repeated measure, randomized controlled trial aims to evaluate an acceptance-based self-care intervention for community-dwelling older adults with multimorbidity.
- Conditions
- Older Adults (60 - 85 Years Old), Self-care, Multimorbidity
- Trial name
- NCT07882992
- Testing
- Acceptance-based activities, Self-care activities
- Where
- Hong Kong
- Volunteers
- 306 people
- Sponsor
- Chinese University of Hong Kong
Thoracotomy, Toracosurgery
Preoperative Nutritional Status and Postoperative Outcomes in Geriatric Lung Resection
Malnutrition is a common comorbidity in patients undergoing thoracic surgery. Furthermore, chronic diseases, polypharmacy, low nutrient intake, reduced appetite, and psychological factors-all frequently observed in geriatric…
- Conditions
- Thoracotomy, Toracosurgery, Thoracic Anesthesia, Older Adults (65 Years and Older)
- Trial name
- NCT07889336
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Social Isolation in Older Adults, Poverty
Multimodal Training With Immersive Virtual Reality to Improve the Cognitive Health and Emotional Well-being of Older Women Living Alone
This study aims to evaluate the effectiveness of an immersive virtual reality-based multimodal intervention (VirtualDONA) to improve cognitive health and emotional well-being in older women living alone and at risk of poverty.
- Trial name
- VirtualDONA (NCT06956794)
- Testing
- VirtualDONA Multimodal Program
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Consorci Sanitari de Terrassa
Older Adults, Older Adults (65 Years and Older)
SOC-based Behavioral Intervention to Promote Walking
Drawing on the Selection, Optimization, and Compensation (SOC) model of adaptive development, this study tested whether a structured behavioral intervention could enhance walking activity and well-being through improvements in…
- Trial name
- SOCWalk (NCT07312331)
- Testing
- SOC-based walking intervention, general health education program
- Where
- China
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Ling Yang
Age-Related Balance Impairment, Healthy Older Adults
Effects of Dynamic Neuromuscular Stabilization Exercises Versus Balance Exercises in Older Adults
The aim of this study is to compare the effects of Dynamic Neuromuscular Stabilization (DNS) based exercises and balance exercises on functional capacity, balance, muscle strength, and quality of life in older adults.
- Trial name
- NCT07495280
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Balance Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Heart Failure, Older Adults (65 Years and Older)
Development and Evaluation of a Disease-oriented Scenario Game to Promote ACP Among Older Adults and Family Caregivers
Current advance care planning (ACP) tabletop games mostly focus on exploring "personal values." While a few explore care preferences through "hypothetical scenarios," they are not disease-oriented, which can create discrepancies…
- Conditions
- Heart Failure, Older Adults (65 Years and Older), Family Caregivers, Life Support Treatment
- Trial name
- NCT07883369
- Testing
- tabletop game, ACP Exercise Book
- Where
- Taiwan
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Gastrointestinal Cancers, Frailty at Older Adults
FRAIL and FiND for Chemotherapy Toxicity in GI Cancer
Older adults with gastrointestinal cancer may experience serious side effects during chemotherapy, particularly when they have reduced physical strength, functional limitations, or other health conditions.
- Conditions
- Gastrointestinal Cancers, Frailty at Older Adults, Chemotherapy
- Trial name
- FRAIL-GI (NCT07272538)
- Testing
- No Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Ankara Etlik City Hospital
Older Adults Institutionalized in Residential Homes
A Virtual Reality Program for Nursing Home Residents With Physical Disabilities
This project will evaluate how well the immersive virtual reality psychological program works in residential care homes and how it can be used in everyday practice.
- Trial name
- NCT07879677
- Testing
- Psychological intervention
- Volunteers
- 400 people
- Sponsor
- Tung Wah College
Older Adults, Nursing Homes
Technology Use, Safe Health Information, and Artificial Intelligence Among Older Adults
Objective The aim of this research is to evaluate how improving the technology use skills of older adults in nursing homes changes their perceptions of access to safe health information and the use of artificial intelligence.
- Conditions
- Older Adults, Nursing Homes, Artifical Intelligence, Technology Use
- Trial name
- NCT07881614
- Testing
- E-Health Literacy Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ondokuz Mayıs University
Older Adults With Complex Care Needs
Digital Bridge: Using Technology to Support Patient-centered Care Transitions From Hospital to Home
Older adults who live with multiple chronic conditions are more likely to experience frequent admissions and discharges from hospital. These transitions are often challenging and leave people at risk of readmission.
- Trial name
- DB (NCT04287192)
- Testing
- Digital Bridge:Tool Intervention
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Gastrointestinal Cancers, Frailty
Longitudinal Geriatric Vulnerability, Chemotherapy Toxicity, and Functional Outcomes in Older Adults With Gastrointestinal Cancer
Older adults with gastrointestinal cancers may be more likely to experience side effects from chemotherapy and difficulties with everyday activities. These problems are not always explained by age alone.
- Conditions
- Gastrointestinal Cancers, Frailty, Sarcopenia in Elderly, Malnutrition Elderly
- Trial name
- VITAL-GI (NCT07184047)
- Testing
- Standard-of-Care Systemic Chemotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Ankara Etlik City Hospital
Preoperative Prehabilitation in Older Adults Undergoing Hepatectomy
Prehabilitation Before Liver Surgery in Older Adults
Many older adults who need liver surgery (hepatectomy) are physically weak before their operation. This can make recovery harder and may lead to more complications after surgery.
- Trial name
- NCT07877311
- Testing
- Preoperative Prehabilitation Program
- Where
- 6 sites in China
- Volunteers
- 500 people
- Sponsor
- Lining Xu
Balance Control in Elderly, Falls (Accidents) in Old Age
Turkish Adaptation of the Multidimensional Falls Efficacy Scale in Older Adults
Falls are a major health concern among older adults and can lead to injuries, reduced independence, and a lower quality of life.
- Conditions
- Balance Control in Elderly, Falls (Accidents) in Old Age, Older Adults (65 Years and Older)
- Trial name
- NCT07878832
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Gazi University
Chronic Insomnia, Older Adults
Brief Behavioral Therapy for Insomnia (BBTi) in Middle-aged and Older Adults With Chronic Insomnia
This study aims to investigate whether a nurse-led brief behavioral therapy can effectively improve chronic insomnia and sleep health in older adults.
- Conditions
- Chronic Insomnia, Older Adults, Sleep Hygiene, Sleep Health
- Trial name
- NCT06073990
- Testing
- Brief Behavioral Treatment for Insomnia (BBTi)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Cheng-Kung University Hospital
Fall Risk in Middle-Aged and Older Adults
Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
This single-arm pre-post study will enroll 50 participants aged 52-65 years who will undergo a 4-week AI-assisted exercise intervention.
- Trial name
- NCT07876011
- Testing
- AI-assited exercise
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Older Adults (60 - 85 Years Old), Sarcopenia
Evaluation of Sarcopenia and Muscle Biomechanics in Older Adults After Lumbar Fusion Surgery
Abstract Background: Lumbar fusion (LF) surgery successfully restores the mechanical stability of the spine; however, postoperative kinesiophobia and complications can trigger secondary sarcopenia.
- Conditions
- Older Adults (60 - 85 Years Old), Sarcopenia, Lumbar Fusion Surgery, Low Back Pain
- Trial name
- NCT07866807
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Karamanoğlu Mehmetbey University
Mobility Impairment, Community Dwelling Older Adults
Motor Imagery and Turning Practice to Improve Mobility: Pilot Trial
The goal of this clinical trial is to evaluate whether combining in-person turning practice with home-based Motor Imagery Therapy (MIT) is feasible and may improve mobility in community-dwelling older adults aged 65 years and…
- Trial name
- MI-TURN (NCT07705360)
- Testing
- Motor Imagery Therapy, Stress Management Education, Locomotor Turning Practice
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boise State University
Physical Function in Older Adults
Application-Based Personalized Exercise Program in Older Adults
This study aims to evaluate the feasibility, usability, adherence, and potential effects of an application-based personalized multicomponent exercise program in older adults.
- Trial name
- NCT07872176
- Testing
- Application-Based Personalized Multicomponent Exercise Program
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital