Upper Extremity DysfunctionNCT06905444
Effects of Multimodal Therapy Versus Myofascial Release Techniques in Patient With Upper Cross Syndrome
A study testing Myofascial Release Technique and Multimodal Therapy in people with Upper Extremity Dysfunction, run by Superior University at 1 site in Pakistan.
Trial summary
Upper Cross Syndrome (UCS) is a frequent condition which is most commonly encountered in the musculoskeletal disorders showing a characteristics pattern of muscular imbalance and dysfunction in the joints of the neck and shoulder region. Read more about this study
- Who is it for?
- Ages 20 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Upper Extremity Dysfunction
- What is being tested?
- Myofascial Release Technique and Multimodal Therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 sitePakistan
- Study dates
- 20 Mar 2025to 20 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Diagnosed by physician with sign and symptoms includes muscle in neck, chest and shoulder become overactive or underactive creating the X shape.
- Office worker.
- Aged 20 to 40 years.
- Male and females.
Who cannot join
- Recent trauma or surgery to the neck or shoulder region.
- Cancer or Metastasis in the neck or shoulder region.
- Infection or Abscess in the neck or shoulder region.
- Neurological conditions.
Trial locations and contacts
1 site in 1 country.
About this study
Upper Cross Syndrome (UCS) is a frequent condition which is most commonly encountered in the musculoskeletal disorders showing a characteristics pattern of muscular imbalance and dysfunction in the joints of the neck and shoulder region. Upper Cross Syndrome remains a prevalent and debilitating condition, despite optimal approaches aimed at reducing pain and improving function.
Read the detailed description
This study investigates the additional benefits of Multimodal Therapy and Myofascial Release Technique in individuals with Upper Cross Syndrome. Rooted .The researcher employs a randomized controlled trial methodology. Participants are divided into two groups: one receiving Multimodal Therapy, and the other receiving Myofascial Release Techniques. Outcomes are assessed over a 6-week period, focusing on pain levels, Posture and functional disability by goniometer, Numeric pain rating scale (NPRS), Neck disability index (NDI) scores and REEDCO posture assessment scale.
- Conditions
- Upper Extremity Dysfunction
- Being tested
- Myofascial Release Technique, Multimodal Therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Myofascial Release TechniqueCombination product
"GROUP A (Multimodal Therapy) Group A was treated with multimodal therapy for 30-45 minutes for 2 sessions per week for 6 weeks. Postural education like correct posture and forward head posture exercises like chin tuck in. Patient was sitting on chair. Therapist was standing on side of patient treated part. Strengthening exercises for the deep cervical flexors, shoulder blade stabilizers, and core muscles with 3 Sets of 3 repetitions with hold for 5 seconds of each exercise. Then breathing exercises for 1 minute. Then grade A (pain free range) cervical spine mobilization 1 Set of 3 repetition. During entire treatment session, the therapist kept close eye on patient's discomfort.
Multimodal TherapyCombination product
Group B (Myofascial Release Technique) Group B was treated with multimodal therapy for 30-45 minutes for 2 sessions per week for 6 weeks. Palpate the muscles and fascia to identify areas of restriction. Apply gentle, sustained pressure to the restricted area using the fingertips or knuckles for Fascial Unwinding. Hold the pressure for 3-5 minutes to allow the fascia to release. Encourage the patient to breathe deeply and slowly to promote relaxation. The stretching of tight muscles 1 set of 3 repetitions. Apply gentle, sustained pressure to release tension of these tight muscles, Suboccipital, Scalene, Pectoralis Major, Trapezius, Levator Scapulae
| Study group | Role | What they receive |
|---|---|---|
| Myofascial Release Technique | Experimental | Not described Receives: Combination Product: Myofascial Release Technique |
| Multimodal Therapy | Active comparator | Not described Receives: Combination Product: Multimodal Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
NUMERIC PAIN RATING SCALE (NPRS)
The 11-point numeric scale ranges from '0' representing "no pain" to feed '10' representing "pain as bad as you can imagine" or "worst pain imaginable".
Measured: 12 Months
NECK DIABILITY INDEX (NDI)
The questionnaire has been designed to evaluate how cervical pain affects ability in managing daily routine functions. There are 10 sections includes 10 questions related to pain intensity, personal care, weight lifting, reading, headaches, concentration, work , driving, sleeping and recreations. Scale between 0-5 score. Total score is 50. 22% or more score is considering significant activities of daily living disability.
Measured: 12 Months
REEDCO POSTURE ASSESSMENT SCALE
Standard tool for objective and quality measurement of postural deviation association with pictures. This includes name, sex, age, center, date and physiotherapist. The total score is out of 100. Normal range between 80-100% of ROM. Mild restriction 60-79% ROM.Moderate restriction 40-59% and Severe restriction: 0-39% ROM. Interpretation of scale is Good -10, Fair -5, Poor - 0 the assessment of muscle.
Measured: 12 Months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Apr 2025
- Study start20 Mar 2025
- Primary completion20 Jun 2025 (estimated)
- Study completion20 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Upper Extremity DysfunctionStudies of the same condition, open and under way.
- More trials run by Superior UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Superior University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Muhammad Naveed Babur, Superior University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06905444
- Sponsor's protocol ID
- MSRSW/Batch-Fall23/785
- Status last verified
- May 2025
- First submitted
- 25 Mar 2025
- Last updated
- 20 May 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Multimodal Therapy Versus Myofascial Release Techniques in Patient With Upper Cross Syndrome
- ClinicalTrials.gov ID
- NCT06905444
- Acronym / sponsor ID
- MSRSW/Batch-Fall23/785
- Conditions
- Upper Extremity Dysfunction
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Superior UniversityUniversity, hospital or other
- Study start
- 20 Mar 2025 (actual)
- Primary completion
- 20 Jun 2025 (estimated)
- Study completion
- 20 Feb 2026 (estimated)
- First posted
- 1 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Upper Cross Syndrome (UCS) is a frequent condition which is most commonly encountered in the musculoskeletal disorders showing a characteristics pattern of muscular imbalance and dysfunction in the joints of the neck and shoulder region. Upper Cross Syndrome remains a prevalent and debilitating condition, despite optimal approaches aimed at reducing pain and improving function.
Detailed description
This study investigates the additional benefits of Multimodal Therapy and Myofascial Release Technique in individuals with Upper Cross Syndrome. Rooted .The researcher employs a randomized controlled trial methodology. Participants are divided into two groups: one receiving Multimodal Therapy, and the other receiving Myofascial Release Techniques. Outcomes are assessed over a 6-week period, focusing on pain levels, Posture and functional disability by goniometer, Numeric pain rating scale (NPRS), Neck disability index (NDI) scores and REEDCO posture assessment scale.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Myofascial Release Technique | Experimental | Combination Product: Myofascial Release Technique |
| Multimodal Therapy | Active comparator | Combination Product: Multimodal Therapy |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Diagnosed by physician with sign and symptoms includes muscle in neck, chest and shoulder become overactive or underactive creating the X shape.
- Office worker.
- Aged 20 to 40 years.
- Male and females.
Key exclusion criteria (4 listed)
- Recent trauma or surgery to the neck or shoulder region.
- Cancer or Metastasis in the neck or shoulder region.
- Infection or Abscess in the neck or shoulder region.
- Neurological conditions.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Myofascial Release Technique"GROUP A (Multimodal Therapy) Group A was treated with multimodal therapy for 30-45 minutes for 2 sessions per week for 6 weeks. Postural education like correct posture and forward head posture exercises like chin tuck in. Patient was sitting on chair. Therapist was standing on side of patient treated part. Strengthening exercises for the deep cervical flexors, shoulder blade stabilizers, and core muscles with 3 Sets of 3 repetitions with hold for 5 seconds of each exercise. Then breathing exercises for 1 minute. Then grade A (pain free range) cervical spine mobilization 1 Set of 3 repetition. During entire treatment session, the therapist kept close eye on patient's discomfort. | Combination product | Myofascial Release Technique |
| Multimodal TherapyGroup B (Myofascial Release Technique) Group B was treated with multimodal therapy for 30-45 minutes for 2 sessions per week for 6 weeks. Palpate the muscles and fascia to identify areas of restriction. Apply gentle, sustained pressure to the restricted area using the fingertips or knuckles for Fascial Unwinding. Hold the pressure for 3-5 minutes to allow the fascia to release. Encourage the patient to breathe deeply and slowly to promote relaxation. The stretching of tight muscles 1 set of 3 repetitions. Apply gentle, sustained pressure to release tension of these tight muscles, Suboccipital, Scalene, Pectoralis Major, Trapezius, Levator Scapulae | Combination product | Multimodal Therapy |
Primary outcome
NUMERIC PAIN RATING SCALE (NPRS)
Time frame: 12 Months
The 11-point numeric scale ranges from '0' representing "no pain" to feed '10' representing "pain as bad as you can imagine" or "worst pain imaginable".
NECK DIABILITY INDEX (NDI)
Time frame: 12 Months
The questionnaire has been designed to evaluate how cervical pain affects ability in managing daily routine functions. There are 10 sections includes 10 questions related to pain intensity, personal care, weight lifting, reading, headaches, concentration, work , driving, sleeping and recreations. Scale between 0-5 score. Total score is 50. 22% or more score is considering significant activities of daily living disability.
REEDCO POSTURE ASSESSMENT SCALE
Time frame: 12 Months
Standard tool for objective and quality measurement of postural deviation association with pictures. This includes name, sex, age, center, date and physiotherapist. The total score is out of 100. Normal range between 80-100% of ROM. Mild restriction 60-79% ROM.Moderate restriction 40-59% and Severe restriction: 0-39% ROM. Interpretation of scale is Good -10, Fair -5, Poor - 0 the assessment of muscle.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 May 2025.
- Individual participant dataSharing planned: No
Related trials for Upper Extremity Dysfunction
RecruitingPhase 3
A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)
Metabolic Dysfunction-associated Steatohepatitis
Recruiting
Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study
Multiple Sclerosis (MS) - Relapsing-remitting, Upper Extremity Dysfunction
Not yet recruitingObservational study
From Blast Injury to Multicompartment Dysfunction:
Compartment Syndrome, Compartment Syndrome Nontraumatic Lower Extremity
Not yet recruiting
Radiofrequency and Pelvic Floor-Core Exercise for Chronic Low Back Pain in Women With Pelvic Floor Dysfunction
Chronic Low Back Pain, Urinary Incontinence
RecruitingPhase 3
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Myofascial Release Technique and Multimodal Therapy in people with Upper Extremity Dysfunction, run by Superior University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 20 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NUMERIC PAIN RATING SCALE (NPRS) (time frame: 12 Months). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 May 2025.