Carpal Tunnel SyndromeNCT06905769
Effects of Aquatic Therapy Versus Neuro-dynamic Technique for the Treatment of Carpal Tunnel Syndrome Patient
A study testing Aquatic Therapy and Neuro-Dynamic Technique in people with Carpal Tunnel Syndrome, run by Superior University at 1 site in Pakistan.
Trial summary
Carpal Tunnel Syndrome (CTS) is a common neurological disorder due to entrapment of median nerve which runs from the forearm into the hand through a tunnel, compressed or pinched due to anatomical factors, such as a narrow carpal tunnel. Widespread condition that affects 3-6% of the general population worldwide. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Carpal Tunnel Syndrome
- What is being tested?
- Aquatic Therapy and Neuro-Dynamic Technique
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 sitePakistan
- Study dates
- 20 Mar 2025to 20 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosed with mild-to-moderate carpal tunnel syndrome by Neuromuscular Physician
- Participants who presented with unilateral CTS with symptoms reported up to 3 months
- Male and female
- Aged 18 years or older
Who cannot join
- Patients with non-specified stage of CTS,median nerve entrapment in TOS, Cervical Radiculpathy
- Participants presents with co-morbidities,Hx of CTS (e.g., pregnancy, diabetes, trauma, congenital disorders, obesity, post-surgical release, and hypothyroidism)
- Cardiovascular disease, thenar muscle atropy"
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Aquatic Therapy Versus Neuro-dynamic Technique for the Treatment of Carpal Tunnel Syndrome Patient: A Randomized Clinical Trial
Carpal Tunnel Syndrome (CTS) is a common neurological disorder due to entrapment of median nerve which runs from the forearm into the hand through a tunnel, compressed or pinched due to anatomical factors, such as a narrow carpal tunnel. Widespread condition that affects 3-6% of the general population worldwide. Carpal Tunnel Syndrome (CTS) a prevalent and debilitating condition leading to disability despite optimal interventions to rehabilitation that aimed to reducing pain and improving neural function status in Carpal Tunnel Syndrome Patients .
Read the detailed description
This study investigates the additional benefits of Aquatic Therapy and Neuro-dynamic Technique in Carpal Tunnel Syndrome Patients .The researcher employs a randomized controlled trial methodology. Participants are divided into two groups: one receiving Aquatic Therapy, and the other receiving Neuro-dynamic Technique.
Outcomes are assessed over an 8-week period, focusing on pain levels and neural function restoration and grip strength. The significance of this study lies in its potential to enhance current treatment protocols, offering a more effective, intervention to alleviate symptoms and improve the quality of life, neural restoration for those suffering Carpal Tunnel Syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome
- Being tested
- Aquatic Therapy, Neuro-Dynamic Technique
- Medical subject headings
- Carpal Tunnel Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Aquatic TherapyCombination product
Group A was treated with Aquatic Therapy for 30-45 minutes for 3 sessions per week for 8 weeks . Patient should Seated .Therapist will standing or seated beside the patient Therapist Perform gentle stretching on wrist, hand, and finger joints. Exercises to improve range of motion and reduce stiffness. Then perform aquatic therapy for 10 minutes. Therapist instruct patients hands in bath tube. Water temperature 88°F - 94°F (31°C - 34°C).Water depth is Waist-deep or deeper depending on patient comfort
Neuro-Dynamic TechniqueDiagnostic test
Group B (Neuro-Dynamic Technique) Group B was treated with Neuro-Dynamic Technique for 15 minutes 3 sessions per week for 8 weeks. Patient should Seated or supine with the affected hand relaxed. Therapist will standing or seated beside the patient. Techniques Time duration is 3 minutes for each technique. wrist distraction 3 sets for 3 minute rhythmic and gentle stretching of the transverse carpel ligament Release of palmar fascia gliding of finger flexor tendons release of upper forearm muscle and fascia.
| Study group | Role | What they receive |
|---|---|---|
| Aquatic Therapy | Experimental | Not described Receives: Combination Product: Aquatic Therapy |
| Neuro-Dynamic Technique | Experimental | Not described Receives: Diagnostic Test: Neuro-Dynamic Technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
NUMERIC PAIN RATING SCALE (NPRS)
The 11-point numeric scale ranges from '0' representing "no pain" to '10' representing "pain as bad as you can imagine" or "worst pain imaginable". The NPRS is a valid and reliable scale to measure pain intensity. NPRS demonstrates strong correlation validity with other established pain measurement scales, making it a reliable tool for clinical assessments.
Measured: 12 Months
Boston Carpal Tunnel Questionnaire (BCTQ)
The questionnaire has been designed to evaluate Assess the severity of CTS symptoms and functional impairment. The total number of questions is 19, total score is 95(sum of 2 subscales) in the BCTQ. Symptom Severity Scale (SSS): 11 items assessing the severity of CTS symptoms, such as numbness, tingling, and pain. Functional Status Scale (FSS) 8 items evaluating the impact of CTS on daily activities, such as grasping, gripping, an carrying. Symptom Severity Scale (SSS): Scores range from 1-5, with higher scores indicating more severe symptoms Functional Status Scale (FSS): Scores range from 1-5, with higher scores indicating greater functional impairment .Reliability 0.95% and Validity 0.80%.
Interpretation
Symptom Severity Scale (SSS) Mild symptoms: 1-2 Moderate symptoms: 2-3 Severe symptoms: 3-4 Very severe symptoms: 4-5
Measured: 12 Months
Grip Strength
Digital Hand Dynamometer is a device used to measure grip strength, which is the force exerted by the hand when grasping an object. Hand Dynamometer units of measurement typically represents the maximum grip strength measured in units Kilograms (kg),Pounds (lb) And Newtons (N). Standard-range dynamometers: 0-100 kg (0-220 lb).
Normal Values for Grip Strength Adult Men: 35-55 kg Adult Women: 20-35 kg
Interpretation
Mild Weakness: 10-20% below normal range. Moderate Weakness: 20-40% below normal range. Severe Weakness: 40-60% below normal range. Profound Weakness: More than 60% below normal range."
Measured: 12 Months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Apr 2025
- Study start20 Mar 2025
- Primary completion20 Jun 2025 (estimated)
- Study completion20 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Carpal Tunnel SyndromeStudies of the same condition, open and under way.
- More trials run by Superior UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Superior University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Muhammad Naveed Babur, Superior University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06905769
- Sponsor's protocol ID
- MSRSW/Batch-Fall23/787
- Status last verified
- Mar 2025
- First submitted
- 25 Mar 2025
- Last updated
- 1 Apr 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Aquatic Therapy Versus Neuro-dynamic Technique for the Treatment of Carpal Tunnel Syndrome Patient: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT06905769
- Acronym / sponsor ID
- MSRSW/Batch-Fall23/787
- Conditions
- Carpal Tunnel Syndrome
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Superior UniversityUniversity, hospital or other
- Study start
- 20 Mar 2025 (actual)
- Primary completion
- 20 Jun 2025 (estimated)
- Study completion
- 20 Feb 2026 (estimated)
- First posted
- 1 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Carpal Tunnel Syndrome (CTS) is a common neurological disorder due to entrapment of median nerve which runs from the forearm into the hand through a tunnel, compressed or pinched due to anatomical factors, such as a narrow carpal tunnel. Widespread condition that affects 3-6% of the general population worldwide. Carpal Tunnel Syndrome (CTS) a prevalent and debilitating condition leading to disability despite optimal interventions to rehabilitation that aimed to reducing pain and improving neural function status in Carpal Tunnel Syndrome Patients .
Detailed description
This study investigates the additional benefits of Aquatic Therapy and Neuro-dynamic Technique in Carpal Tunnel Syndrome Patients .The researcher employs a randomized controlled trial methodology. Participants are divided into two groups: one receiving Aquatic Therapy, and the other receiving Neuro-dynamic Technique.
Outcomes are assessed over an 8-week period, focusing on pain levels and neural function restoration and grip strength. The significance of this study lies in its potential to enhance current treatment protocols, offering a more effective, intervention to alleviate symptoms and improve the quality of life, neural restoration for those suffering Carpal Tunnel Syndrome (CTS).
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Aquatic Therapy | Experimental | Combination Product: Aquatic Therapy |
| Neuro-Dynamic Technique | Experimental | Diagnostic Test: Neuro-Dynamic Technique |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Diagnosed with mild-to-moderate carpal tunnel syndrome by Neuromuscular Physician
- Participants who presented with unilateral CTS with symptoms reported up to 3 months
- Male and female
- Aged 18 years or older
Key exclusion criteria (3 listed)
- Patients with non-specified stage of CTS,median nerve entrapment in TOS, Cervical Radiculpathy
- Participants presents with co-morbidities,Hx of CTS (e.g., pregnancy, diabetes, trauma, congenital disorders, obesity, post-surgical release, and hypothyroidism)
- Cardiovascular disease, thenar muscle atropy"
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Aquatic TherapyGroup A was treated with Aquatic Therapy for 30-45 minutes for 3 sessions per week for 8 weeks . Patient should Seated .Therapist will standing or seated beside the patient Therapist Perform gentle stretching on wrist, hand, and finger joints. Exercises to improve range of motion and reduce stiffness. Then perform aquatic therapy for 10 minutes. Therapist instruct patients hands in bath tube. Water temperature 88°F - 94°F (31°C - 34°C).Water depth is Waist-deep or deeper depending on patient comfort | Combination product | Aquatic Therapy |
| Neuro-Dynamic TechniqueGroup B (Neuro-Dynamic Technique) Group B was treated with Neuro-Dynamic Technique for 15 minutes 3 sessions per week for 8 weeks. Patient should Seated or supine with the affected hand relaxed. Therapist will standing or seated beside the patient. Techniques Time duration is 3 minutes for each technique. wrist distraction 3 sets for 3 minute rhythmic and gentle stretching of the transverse carpel ligament Release of palmar fascia gliding of finger flexor tendons release of upper forearm muscle and fascia. | Diagnostic test | Neuro-Dynamic Technique |
Primary outcome
NUMERIC PAIN RATING SCALE (NPRS)
Time frame: 12 Months
The 11-point numeric scale ranges from '0' representing "no pain" to '10' representing "pain as bad as you can imagine" or "worst pain imaginable". The NPRS is a valid and reliable scale to measure pain intensity. NPRS demonstrates strong correlation validity with other established pain measurement scales, making it a reliable tool for clinical assessments.
Boston Carpal Tunnel Questionnaire (BCTQ)
Time frame: 12 Months
The questionnaire has been designed to evaluate Assess the severity of CTS symptoms and functional impairment. The total number of questions is 19, total score is 95(sum of 2 subscales) in the BCTQ. Symptom Severity Scale (SSS): 11 items assessing the severity of CTS symptoms, such as numbness, tingling, and pain. Functional Status Scale (FSS) 8 items evaluating the impact of CTS on daily activities, such as grasping, gripping, an carrying. Symptom Severity Scale (SSS): Scores range from 1-5, with higher scores indicating more severe symptoms Functional Status Scale (FSS): Scores range from 1-5, with higher scores indicating greater functional impairment .Reliability 0.95% and Validity 0.80%. Interpretation Symptom Severity Scale (SSS) Mild symptoms: 1-2 Moderate symptoms: 2-3 Severe symptoms: 3-4 Very severe symptoms: 4-5
Grip Strength
Time frame: 12 Months
Digital Hand Dynamometer is a device used to measure grip strength, which is the force exerted by the hand when grasping an object. Hand Dynamometer units of measurement typically represents the maximum grip strength measured in units Kilograms (kg),Pounds (lb) And Newtons (N). Standard-range dynamometers: 0-100 kg (0-220 lb). Normal Values for Grip Strength Adult Men: 35-55 kg Adult Women: 20-35 kg Interpretation Mild Weakness: 10-20% below normal range. Moderate Weakness: 20-40% below normal range. Severe Weakness: 40-60% below normal range. Profound Weakness: More than 60% below normal range."
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Apr 2025.
- Individual participant dataSharing planned: No
Related trials for Carpal Tunnel Syndrome
Not yet recruitingObservational study
Postural Control and Balance Performance in Patients With Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS), Postural Assessment
Recruiting
Comparison of Wrist Splint Positions in Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS), Peripheral Neuropathies
Recruiting
Effects of Repetitive Peripheral Magnetic Stimulation(rPMS) on CTS(Carpal Tunnel Syndrome)
Carpal Tunnel Syndrome (CTS)
Recruiting
Hand Function Outcome After the Application of Transfer Energy Capacitive and Resistive on Post-burn Patients Presented With Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) Post-burn
Not yet recruiting
Effect of Progressive Gamified Motor Rehabilitation After Carpal Tunnel Release
Carpal Tunnel Surgery
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Aquatic Therapy and Neuro-Dynamic Technique in people with Carpal Tunnel Syndrome, run by Superior University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 1 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NUMERIC PAIN RATING SCALE (NPRS) (time frame: 12 Months). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Apr 2025.