Lung Cancer ScreeningNCT06909981
Community-Based Engagement to Improve Lung Cancer Screening and Outcomes: The "Our Lungs Our Health" Study
A study testing Low-Dose Computed Tomography Scan in people with Lung Cancer Screening, run by Brigham and Women's Hospital.
Trial summary
The main goal of this pilot study is to understand the impact of a mobile lung cancer screening clinics in individuals from neighborhoods and communities with less access to resources in Boston, Massachusetts who are at high risk for lung cancer. Read more about this study
- Who is it for?
- Ages 50 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Lung Cancer Screening
- What is being tested?
- Low-Dose Computed Tomography Scan
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 125 participants
- Where
- No sites listed yet
- Study dates
- 1 May 2026to 1 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Ability to understand and the willingness to sign a written informed consent document prior to any study-related procedures.
- Willing to undergo treatment.
- Adults between the ages of 50 and 80 years.
- No recent CT imaging within the last year.
- Currently smokes tobacco or has quit smoking tobacco within the past 15 years.
- Has a tobacco smoking history of at least 20 pack years (i.e. one pack per day for the last 20 years or equivalent).
- Has never been diagnosed with lung cancer.
Who cannot join
- Adults/children less than 50 years, or greater than 80 years of age.
- Has never smoked tobacco.
- Has smoked tobacco but quit more than 15 years ago.
- Has a tobacco smoking history of less than 20 pack years.
- Presence of major comorbidity(ies) that could prevent treatment.
- Previous diagnosis of lung cancer.
- In the opinion of the investigator, the subject is not an appropriate candidate for the study.
About this study
Official title: Community-Based Engagement to Improve Lung Cancer Screening and Outcomes
The main goal of this pilot study is to understand the impact of a mobile lung cancer screening clinics in individuals from neighborhoods and communities with less access to resources in Boston, Massachusetts who are at high risk for lung cancer. A secondary goal of this pilot study is to understand how social determinants of health impact these neighborhoods and communities. Another secondary goal of this pilot study is to see if video recording of participants speaking to their future selves and sending the videos back to participants to encourage them to get lung cancer screening after one year can be administered in a mobile lung cancer screening setting. The questions this study aims to answer are:
- Is mobile lung cancer screening is feasible and acceptable?
- Is collecting social needs data during the mobile lung cancer screening clinics feasible?
- Is creating video recordings of patients encouraging their future selves to get lung cancer screening after one year feasible?
Read more
Participants will:
- Complete an intake survey, providing information about their demographic, medical, and social needs information.
- Undergo a shared decision-making conversation to determine whether lung cancer screening should be done.
- Undergo lung cancer screening.
- Undergo a debriefing conversation and fill out an acceptability survey.
- Record a video speaking to their future selves about the importance of annual lung cancer screening, with the video to be sent back to them after roughly one year.
- Undergo a semi-structured phone interview between four and eight weeks after lung cancer screening date.
- Conditions
- Lung Cancer Screening
- Being tested
- Low-Dose Computed Tomography Scan
- Keywords
- Lung Cancer Screening
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Low-Dose Computed Tomography ScanRadiation
Also called CT Scan, LDCT Scan, CAT Scan
Imaging of chest to screen for lung cancer.
| Study group | Role | What they receive |
|---|---|---|
| Lung Cancer Screening | Experimental | Participants will complete a baseline questionnaire and undergo a shared decision-making with the study team to determine whether they will receive lung cancer screening. If the participant and team member determine that lung cancer screening should be performed, they will undergo screening. Regardless of whether lung cancer screening is performed, participants will undergo a debriefing conversation. An acceptability survey will be given to participants who underwent lung cancer screening. Those who undergo lung cancer screening will also be video-recorded speaking to their future selves as encouragement to get annual lung cancer screening. Imaging results will be returned to the participant and their care team within two weeks after lung cancer screening. Semi-structured interviews will also be performed with participants who underwent lung cancer screening between four and eight weeks after lung cancer screening. Video footage will be returned to patients after 48 weeks. Receives: Radiation: Low-Dose Computed Tomography Scan |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility of mobile lung cancer screening in target communities in Boston, Massachusetts.
This outcome will be assessed by calculating the raw count of individuals screened at each mobile clinic and the number of individuals unable to be screened due to time constraints.
Measured: During the intervention.
Acceptability of mobile lung cancer screening in target communities in Boston, Massachusetts.
Acceptability will be assessed using semi-structured phone interviews with participants. Responses to questions, themes, and keywords will be analyzed to report attitudes regarding the intervention.
Measured: Between four and eight weeks after the intervention
Secondary outcomes (2)
Feasibility of collecting social determinants of health data during mobile lung cancer screening clinics in underserved communities in Boston, Massachusetts.
Feasibility will be measured using the raw count of completed intake surveys.
Measured: Pre-intervention
Feasibility of administering a video-based intervention to encourage annual lung cancer screening
Participants who undergo mobile lung cancer screening will be recorded speaking to their future selves about the importance of annual lung cancer screening. The video footage will be returned to participants 48 weeks after mobile lung cancer screening to encourage the patient to schedule their next screening.
Measured: From enrollment until the end of the study.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Apr 2025
- Study start1 May 2026 (estimated)
- Primary completion1 Nov 2026 (estimated)
- Study completion1 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lung Cancer ScreeningStudies of the same condition, open and under way.
- More trials run by Brigham and Women's HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Screening
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 125 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Brigham and Women's Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Rian M. Hasson, MD, MPH, FACS, Brigham and Women's Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06909981
- Sponsor's protocol ID
- 24-715
- Status last verified
- Dec 2025
- First submitted
- 21 Mar 2025
- Last updated
- 8 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Community-Based Engagement to Improve Lung Cancer Screening and Outcomes
- ClinicalTrials.gov ID
- NCT06909981
- Acronym / sponsor ID
- 24-715
- Conditions
- Lung Cancer Screening
- Keywords
- Lung Cancer Screening
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 125 participants (estimated)
- Lead sponsor
- Brigham and Women's HospitalUniversity, hospital or other
- Study start
- 1 May 2026 (estimated)
- Primary completion
- 1 Nov 2026 (estimated)
- Study completion
- 1 Nov 2026 (estimated)
- First posted
- 4 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main goal of this pilot study is to understand the impact of a mobile lung cancer screening clinics in individuals from neighborhoods and communities with less access to resources in Boston, Massachusetts who are at high risk for lung cancer. A secondary goal of this pilot study is to understand how social determinants of health impact these neighborhoods and communities. Another secondary goal of this pilot study is to see if video recording of participants speaking to their future selves and sending the videos back to participants to encourage them to get lung cancer screening after one year can be administered in a mobile lung cancer screening setting. The questions this study aims to answer are:
- Is mobile lung cancer screening is feasible and acceptable?
- Is collecting social needs data during the mobile lung cancer screening clinics feasible?
- Is creating video recordings of patients encouraging their future selves to get lung cancer screening after one year feasible?
Participants will:
- Complete an intake survey, providing information about their demographic, medical, and social needs information.
- Undergo a shared decision-making conversation to determine whether lung cancer screening should be done.
- Undergo lung cancer screening.
- Undergo a debriefing conversation and fill out an acceptability survey.
- Record a video speaking to their future selves about the importance of annual lung cancer screening, with the video to be sent back to them after roughly one year.
- Undergo a semi-structured phone interview between four and eight weeks after lung cancer screening date.
Study design
- Primary purpose
- Screening
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Lung Cancer Screening | Experimental | Radiation: Low-Dose Computed Tomography ScanParticipants will complete a baseline questionnaire and undergo a shared decision-making with the study team to determine whether they will receive lung cancer screening. If the participant and team member determine that lung cancer screening should be performed, they will undergo screening. Regardless of whether lung cancer screening is performed, participants will undergo a debriefing conversation. An acceptability survey will be given to participants who underwent lung cancer screening. Those who undergo lung cancer screening will also be video-recorded speaking to their future selves as encouragement to get annual lung cancer screening. Imaging results will be returned to the participant and their care team within two weeks after lung cancer screening. Semi-structured interviews will also be performed with participants who underwent lung cancer screening between four and eight weeks after lung cancer screening. Video footage will be returned to patients after 48 weeks. |
Who may qualify
- Ages
- 50 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- Ability to understand and the willingness to sign a written informed consent document prior to any study-related procedures.
- Willing to undergo treatment.
- Adults between the ages of 50 and 80 years.
- No recent CT imaging within the last year.
- Currently smokes tobacco or has quit smoking tobacco within the past 15 years.
Key exclusion criteria (7 listed)
- Adults/children less than 50 years, or greater than 80 years of age.
- Has never smoked tobacco.
- Has smoked tobacco but quit more than 15 years ago.
- Has a tobacco smoking history of less than 20 pack years.
- Presence of major comorbidity(ies) that could prevent treatment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Low-Dose Computed Tomography ScanAlso: CT Scan, LDCT Scan, CAT ScanImaging of chest to screen for lung cancer. | Radiation | Lung Cancer Screening |
Primary outcome
Feasibility of mobile lung cancer screening in target communities in Boston, Massachusetts.
Time frame: During the intervention.
This outcome will be assessed by calculating the raw count of individuals screened at each mobile clinic and the number of individuals unable to be screened due to time constraints.
Acceptability of mobile lung cancer screening in target communities in Boston, Massachusetts.
Time frame: Between four and eight weeks after the intervention
Acceptability will be assessed using semi-structured phone interviews with participants. Responses to questions, themes, and keywords will be analyzed to report attitudes regarding the intervention.
2 secondary outcomes
Feasibility of collecting social determinants of health data during mobile lung cancer screening clinics in underserved communities in Boston, Massachusetts.
Time frame: Pre-intervention
Feasibility of administering a video-based intervention to encourage annual lung cancer screening
Time frame: From enrollment until the end of the study.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Dec 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Low-Dose Computed Tomography Scan in people with Lung Cancer Screening, run by Brigham and Women's Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Feasibility of mobile lung cancer screening in target communities in Boston, Massachusetts. (time frame: During the intervention.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Dec 2025.