Menstrual IrregularitiesNCT06936436
the Effect of Implanon on Menstrual Patterns
An observational study of Menstrual Irregularities, run by Assiut University.
Trial summary
This study aims to evaluate whether the timing of postpartum Implanon insertion (immediately postpartum, early postpartum, or late postpartum) affects menstrual patterns Read more about this study
- Who is it for?
- Any age, women onlyHealthy volunteers can take part
- Conditions the study is for
- Menstrual Irregularities
- What is being tested?
- Implanon (Etonogestrel)
- How many people
- 200 participants
- Where
- No sites listed yet
- Study dates
- May 2025to Jun 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- Women only
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Women will be grouped into: 1. Immediate postpartum (Insertion within 48 hours of delivery). 2. Early postpartum (Insertion between 4-6 weeks postpartum). 3. Late postpartum (Insertion after 6 weeks postpartum
Who may be able to join
- Postpartum women opting for Implanon as contraception.
- No contraindications to hormonal contraception.
Who cannot join
- . Women with known bleeding disorders.
- Use of other hormonal contraceptives during the study period.
- Postpartum complications such as severe infections or retained products of conception
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: the Effect of Implanon on Menstrual Patterns According to Timing of Insertion After Delivery
This study aims to evaluate whether the timing of postpartum Implanon insertion (immediately postpartum, early postpartum, or late postpartum) affects menstrual patterns
Read the detailed description
- Etonogestrel implants (Implanon) are widely used for postpartum contraception. However, the timing of insertion may influence menstrual patterns, including irregular bleeding, amenorrhea, and prolonged bleeding episodes. Despite the increasing use of immediate postpartum contraception, there is limited research on how the timing of Implanon insertion affects menstrual cycle regulation.
- Furthermore, lactation and hormonal changes postpartum may modify the bleeding patterns in women using Implanon, with breastfeeding women experiencing a higher likelihood of amenorrhea due to prolactin-induced suppression of ovulation.
- This study aims to fill these gaps by systematically comparing menstrual outcomes based on timing of Implanon insertion postpartum
- Conditions
- Menstrual Irregularities
- Being tested
- Implanon (Etonogestrel)
- Medical subject headings
- Menstruation Disturbances
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Implanon (Etonogestrel)Other
implanon is a long acting ,reversible contraceptive implants used to prevent pregnancy
What is being measured
The primary outcome is the main question the study is designed to answer.
The Effect of Implanon on Menstrual Patterns According to Timing of Insertion After Delivery
To compare the effect of Implanon insertion at different postpartum intervals (immediate, early, late) on menstrual cycle patterns
- To assess the prevalence of irregular bleeding, amenorrhea, and prolonged bleeding across different insertion groups.
- To analyze general trends in menstrual changes, regardless of insertion timing.
Measured: baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Apr 2025
- Study startMay 2025 (estimated)
- Primary completionMay 2026 (estimated)
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Menstrual IrregularitiesStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Kholoud Khalid Kamal, Assiut University
- Investigators
- AHMED MOHAMED ABBAS, PROF.DR, Study chair, Assiut UniversityMOHAMED SAYED ABDELLAH, PROF.DR, Study chair, Assiut UniversityALAA AHMED MAKHLOUF, DR, Study chair, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06936436
- Sponsor's protocol ID
- effect of implanon
- Status last verified
- Apr 2025
- First submitted
- 13 Apr 2025
- Last updated
- 23 Apr 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Mazza D, Harrison C, Taft A, Brijnath B, Britt H, Hobbs M, Stewart K, Hussainy S. Current contraceptive management in Australian general practice: an analysis of BEACH data. Med J Aust. 2012 Jul 16;197(2):110-4. doi: 10.5694/mja11.11599.
PubMed 22794058Richters J, Grulich AE, de Visser RO, Smith AM, Rissel CE. Sex in Australia: contraceptive practices among a representative sample of women. Aust N Z J Public Health. 2003;27(2):210-6. doi: 10.1111/j.1467-842x.2003.tb00810.x.
PubMed 14696713. Product information: Implanon NXT, Schering-Plough Pty Ltd, 12 November 2010
Product information: Implanon® Implant, Organon (Australia) Pty Ltd, 19 March 2008.
Study at a glance
From the registry record, last updated by the sponsor on 23 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- the Effect of Implanon on Menstrual Patterns According to Timing of Insertion After Delivery
- ClinicalTrials.gov ID
- NCT06936436
- Acronym / sponsor ID
- effect of implanon
- Conditions
- Menstrual Irregularities
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- May 2025 (estimated)
- Primary completion
- May 2026 (estimated)
- Study completion
- Jun 2026 (estimated)
- First posted
- 20 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate whether the timing of postpartum Implanon insertion (immediately postpartum, early postpartum, or late postpartum) affects menstrual patterns
Detailed description
- Etonogestrel implants (Implanon) are widely used for postpartum contraception. However, the timing of insertion may influence menstrual patterns, including irregular bleeding, amenorrhea, and prolonged bleeding episodes. Despite the increasing use of immediate postpartum contraception, there is limited research on how the timing of Implanon insertion affects menstrual cycle regulation.
- Furthermore, lactation and hormonal changes postpartum may modify the bleeding patterns in women using Implanon, with breastfeeding women experiencing a higher likelihood of amenorrhea due to prolactin-induced suppression of ovulation.
- This study aims to fill these gaps by systematically comparing menstrual outcomes based on timing of Implanon insertion postpartum
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Women will be grouped into: 1. Immediate postpartum (Insertion within 48 hours of delivery). 2. Early postpartum (Insertion between 4-6 weeks postpartum). 3. Late postpartum (Insertion after 6 weeks postpartum
Key inclusion criteria (2 listed)
- Postpartum women opting for Implanon as contraception.
- No contraindications to hormonal contraception.
Key exclusion criteria (3 listed)
- . Women with known bleeding disorders.
- Use of other hormonal contraceptives during the study period.
- Postpartum complications such as severe infections or retained products of conception
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Implanon (Etonogestrel)implanon is a long acting ,reversible contraceptive implants used to prevent pregnancy | Other | – |
Primary outcome
The Effect of Implanon on Menstrual Patterns According to Timing of Insertion After Delivery
Time frame: baseline
To compare the effect of Implanon insertion at different postpartum intervals (immediate, early, late) on menstrual cycle patterns * To assess the prevalence of irregular bleeding, amenorrhea, and prolonged bleeding across different insertion groups. * To analyze general trends in menstrual changes, regardless of insertion timing.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Apr 2025.
- Background: PubMed 22794058Mazza D, Harrison C, Taft A, Brijnath B, Britt H, Hobbs M, Stewart K, Hussainy S. Current contraceptive management in Australian general practice: an analysis of BEACH data. Med J Aust. 2012 Jul 16;197(2):110-4. doi: 10.5694/mja11.11599.
- Background: PubMed 14696713Richters J, Grulich AE, de Visser RO, Smith AM, Rissel CE. Sex in Australia: contraceptive practices among a representative sample of women. Aust N Z J Public Health. 2003;27(2):210-6. doi: 10.1111/j.1467-842x.2003.tb00810.x.
- Background. Product information: Implanon NXT, Schering-Plough Pty Ltd, 12 November 2010
- BackgroundProduct information: Implanon® Implant, Organon (Australia) Pty Ltd, 19 March 2008.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
AHMED MOHAMED ABBAS, PROF.DR study chair
Assiut University
MOHAMED SAYED ABDELLAH, PROF.DR study chair
Assiut University
ALAA AHMED MAKHLOUF, DR study chair
Assiut University
Questions about this trial
What is this clinical trial studying?
An observational study of Menstrual Irregularities, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 23 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact kholoud khalid KAMAL (01013224377, kholoud.khalid494@GMAIL.COM), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The Effect of Implanon on Menstrual Patterns According to Timing of Insertion After Delivery (time frame: baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06936436, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Apr 2025; AzTrials last refreshed its copy on 31 Oct 2026.