Cervicogenic HeadacheNCT06940167
Comparison of Kinesio Taping and Myofascial Release in Cervicogenic Headache
A study testing Myofascial Release Group and Kinesiology Taping Group in people with Cervicogenic Headache, run by Konya Meram State Hospital at 1 site in Turkey (Türkiye).
Trial summary
Cervicogenic headache (CGH) is defined as a headache accompanied by neck pain, caused by a disorder in the cervical spine, bones, discs, or soft tissue elements. This study is designed as a prospective, case-control, hospital-based study. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Cervicogenic Headache
- What is being tested?
- Myofascial Release Group and Kinesiology Taping Group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 81 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Feb 2025to 31 Aug 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
None listed.
Who cannot join
- Migraine Cluster headache Cervical radiculopathy Entrapment neuropathy Myelopathy Rheumatoid arthritis Undergoing cervical spinal surgery Pregnancy Receiving physical therapy within the last 6 months History of major psychiatric disorders History of uncontrolled systemic diseases (cardiovascular, pulmonary, hepatic, renal, hematological, etc.) History of uncontrolled endocrine diseases (e.g., Diabetes Mellitus, hyperthyroidism, etc.)
- -
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of the Effectiveness of Kinesio Taping and Myofascial Release in Patients With Cervicogenic Headache
Cervicogenic headache (CGH) is defined as a headache accompanied by neck pain, caused by a disorder in the cervical spine, bones, discs, or soft tissue elements. This study is designed as a prospective, case-control, hospital-based study. A total of 90 patients aged 18-65 years who have been suffering from CGH for at least three months and who present to the Physical Medicine and Rehabilitation Clinic of Meram State Hospital between January 2025 and January 2027 will be included in the study. Patients will be informed about the procedures, and informed consent will be obtained. The study will be conducted in accordance with the Declaration of Helsinki. A detailed medical history will be taken from all participants, and a comprehensive physical examination will be performed. Sociodemographic and clinical characteristics such as age, gender, height, weight, education level, employment status, and income level will be recorded. The 90 CGH patients will be divided into three groups.Group 1 (n=30) will receive myofascial release therapy + home exercise program for four weeks, three sessions per week, totaling 12 sessions. Group 2 (n=30) will receive Kinesio taping + home exercise program for four weeks, three sessions per week, totaling 12 sessions. Group 3 (n=30) will receive only a home exercise program for four weeks, three sessions per week, totaling 12 sessions. All evaluations will be conducted by the same researcher at three time points: before treatment (baseline), at the end of treatment (week 4), and one month after the completion of treatment (week 8).The aim of this prospective clinical study is to compare the effectiveness of Kinesio taping and myofascial release therapy in the treatment of cervicogenic headache.
Read the detailed description
This randomized, parallel-group clinical trial aims to compare the effectiveness of kinesio taping and myofascial release therapy in patients diagnosed with cervicogenic headache. The study is based on the hypothesis that both interventions can reduce pain intensity and functional disability, but their relative efficacy remains unclear. The trial is designed to provide clinical evidence to guide physiotherapeutic management of cervicogenic headache.
- Conditions
- Cervicogenic Headache
- Being tested
- Myofascial Release Group, Kinesiology Taping Group, Home Exercise Program (Control Group)
- Keywords
- Cervicogenic headache, Myofascial Release, Kinesio taping
- Medical subject headings
- Post-Traumatic Headache
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Myofascial Release GroupOther
myofascial release therapy combined with a home exercise program: Myofascial release techniques will be applied manually to the cervical and upper trapezius regions by a trained physiotherapist. The intervention will be administered three times per week for four weeks, totaling 12 sessions. In addition, participants will follow a standardized home exercise program designed to improve cervical mobility and reduce muscle tension.
Kinesiology Taping GroupOther
kinesiology taping combined with a home exercise program : Kinesiology tape will be applied to the cervical region following a standardized taping protocol. The taping will be performed by a trained physiotherapist three times per week for four weeks, totaling 12 sessions. The tape will remain on the skin for 3-5 days per application.
Home Exercise Program (Control Group)Other
Home exercise program: The exercise program includes cervical mobility exercises, stretching, and strengthening exercises aimed at improving posture and reducing muscle tension. The intervention will be performed three times per week for four weeks, totaling 12 sessions.
| Study group | Role | What they receive |
|---|---|---|
| Myofascial Release Group | Experimental | Group 1 (n=30) will receive myofascial release therapy + home exercise program for four weeks, three sessions per week, totaling 12 sessions. Receives: Other: Myofascial Release Group; Other: Home Exercise Program (Control Group) |
| Kinesiology Taping Group | Experimental | Group 2 (n=30) will receive Kinesio taping + home exercise program for four weeks, three sessions per week, totaling 12 sessions Receives: Other: Kinesiology Taping Group; Other: Home Exercise Program (Control Group) |
| Home Exercise Group | Experimental | Group 3 (n=30) will receive only a home exercise program for four weeks, three sessions per week, totaling 12 sessions Receives: Other: Home Exercise Program (Control Group) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Cervicogenic Headache Severity Measured by Visual Analog Scale (VAS) at Baseline, 4 Weeks, and 8 Weeks
Headache severity will be assessed using a 10 cm horizontal Visual Analog Scale (VAS), where 0 indicates "no pain" and 10 indicates "worst possible pain." Participants will mark the level of their current headache severity on the scale. Changes will be calculated from baseline to week 4 and week 8.
Measured: Baseline, Week 4 (end of treatment), and Week 8 (1-month follow-up after treatment)
Secondary outcomes (4)
Change in Headache Impact Test (HIT-6) Score at Baseline, 4 Weeks, and 8 Weeks
The HIT-6 is a six-item questionnaire evaluating the impact of headache on daily activities, scored from 36 to 78. Higher scores indicate greater impact.
Measured: Baseline, Week 4, and Week 8
Change in Headache Disability Index (HDI) Score at Baseline, 4 Weeks, and 8 Weeks
The HDI is a 25-item questionnaire assessing the emotional and functional impact of headaches. The total score is used to evaluate disability level.
Measured: Baseline, Week 4, and Week 8
Change in Quality of Life Measured by Short Form-12 (SF-12) at Baseline, 4 Weeks, and 8 Weeks
SF-12 evaluates general health and quality of life across physical and mental domains. Scores are calculated per standard algorithm.
Measured: Baseline, Week 4, and Week 8
Change in Headache Frequency (Number of Headache Days per Month) at Baseline, 4 Weeks, and 8 Weeks
Headache frequency will be recorded using a headache diary. The number of days with headache in the past 4 weeks will be used for assessment.
Measured: Baseline, Week 4, and Week 8
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Apr 2025
- Study start1 Feb 2025
- Primary completion1 Aug 2025
- Study completion31 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cervicogenic HeadacheStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 81 participants (actual)
Sponsor and investigators
- Lead sponsor
- Konya Meram State Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fatma CAGLAYAN AGIR, Konya Meram State Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06940167
- Sponsor's protocol ID
- 2025/5545
- Status last verified
- Nov 2025
- First submitted
- 9 Apr 2025
- Last updated
- 19 Nov 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data (IPD) for all primary and secondary outcome measures (e.g., VAS, HIT-6, NDI, SF-12) will be made available to qualified researchers for secondary analysis. Data will be shared upon reasonable request, beginning 6 months after publication, for a period of 3 years. Access will be granted to researchers with methodologically sound proposals by contacting the Principal Investigator via institutional email.
Study at a glance
From the registry record, last updated by the sponsor on 19 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effectiveness of Kinesio Taping and Myofascial Release in Patients With Cervicogenic Headache
- ClinicalTrials.gov ID
- NCT06940167
- Acronym / sponsor ID
- 2025/5545
- Conditions
- Cervicogenic Headache
- Keywords
- Cervicogenic headache, Myofascial Release, Kinesio taping
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 81 participants (actual)
- Lead sponsor
- Konya Meram State HospitalUniversity, hospital or other
- Study start
- 1 Feb 2025 (actual)
- Primary completion
- 1 Aug 2025 (actual)
- Study completion
- 31 Aug 2025 (actual)
- First posted
- 23 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cervicogenic headache (CGH) is defined as a headache accompanied by neck pain, caused by a disorder in the cervical spine, bones, discs, or soft tissue elements. This study is designed as a prospective, case-control, hospital-based study. A total of 90 patients aged 18-65 years who have been suffering from CGH for at least three months and who present to the Physical Medicine and Rehabilitation Clinic of Meram State Hospital between January 2025 and January 2027 will be included in the study. Patients will be informed about the procedures, and informed consent will be obtained. The study will be conducted in accordance with the Declaration of Helsinki. A detailed medical history will be taken from all participants, and a comprehensive physical examination will be performed. Sociodemographic and clinical characteristics such as age, gender, height, weight, education level, employment status, and income level will be recorded. The 90 CGH patients will be divided into three groups.Group 1 (n=30) will receive myofascial release therapy + home exercise program for four weeks, three sessions per week, totaling 12 sessions. Group 2 (n=30) will receive Kinesio taping + home exercise program for four weeks, three sessions per week, totaling 12 sessions. Group 3 (n=30) will receive only a home exercise program for four weeks, three sessions per week, totaling 12 sessions. All evaluations will be conducted by the same researcher at three time points: before treatment (baseline), at the end of treatment (week 4), and one month after the completion of treatment (week 8).The aim of this prospective clinical study is to compare the effectiveness of Kinesio taping and myofascial release therapy in the treatment of cervicogenic headache.
Detailed description
This randomized, parallel-group clinical trial aims to compare the effectiveness of kinesio taping and myofascial release therapy in patients diagnosed with cervicogenic headache. The study is based on the hypothesis that both interventions can reduce pain intensity and functional disability, but their relative efficacy remains unclear. The trial is designed to provide clinical evidence to guide physiotherapeutic management of cervicogenic headache.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Myofascial Release Group | Experimental | Other: Myofascial Release Group, Other: Home Exercise Program (Control Group)Group 1 (n=30) will receive myofascial release therapy + home exercise program for four weeks, three sessions per week, totaling 12 sessions. |
| Kinesiology Taping Group | Experimental | Other: Kinesiology Taping Group, Other: Home Exercise Program (Control Group)Group 2 (n=30) will receive Kinesio taping + home exercise program for four weeks, three sessions per week, totaling 12 sessions |
| Home Exercise Group | Experimental | Other: Home Exercise Program (Control Group)Group 3 (n=30) will receive only a home exercise program for four weeks, three sessions per week, totaling 12 sessions |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (0 listed)
Key exclusion criteria (2 listed)
- Migraine Cluster headache Cervical radiculopathy Entrapment neuropathy Myelopathy Rheumatoid arthritis Undergoing cervical spinal surgery Pregnancy Receiving physical therapy within the last 6 months History of major psychiatric disorders History of uncontrolled systemic diseases (cardiovascular, pulmonary, hepatic, renal, hematological, etc.) History of uncontrolled endocrine diseases (e.g., Diabetes Mellitus, hyperthyroidism, etc.)
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Myofascial Release Groupmyofascial release therapy combined with a home exercise program: Myofascial release techniques will be applied manually to the cervical and upper trapezius regions by a trained physiotherapist. The intervention will be administered three times per week for four weeks, totaling 12 sessions. In addition, participants will follow a standardized home exercise program designed to improve cervical mobility and reduce muscle tension. | Other | Myofascial Release Group |
| Kinesiology Taping Groupkinesiology taping combined with a home exercise program : Kinesiology tape will be applied to the cervical region following a standardized taping protocol. The taping will be performed by a trained physiotherapist three times per week for four weeks, totaling 12 sessions. The tape will remain on the skin for 3-5 days per application. | Other | Kinesiology Taping Group |
| Home Exercise Program (Control Group)Home exercise program: The exercise program includes cervical mobility exercises, stretching, and strengthening exercises aimed at improving posture and reducing muscle tension. The intervention will be performed three times per week for four weeks, totaling 12 sessions. | Other | Home Exercise Group, Kinesiology Taping Group, Myofascial Release Group |
Primary outcome
Change in Cervicogenic Headache Severity Measured by Visual Analog Scale (VAS) at Baseline, 4 Weeks, and 8 Weeks
Time frame: Baseline, Week 4 (end of treatment), and Week 8 (1-month follow-up after treatment)
Headache severity will be assessed using a 10 cm horizontal Visual Analog Scale (VAS), where 0 indicates "no pain" and 10 indicates "worst possible pain." Participants will mark the level of their current headache severity on the scale. Changes will be calculated from baseline to week 4 and week 8.
4 secondary outcomes
Change in Headache Impact Test (HIT-6) Score at Baseline, 4 Weeks, and 8 Weeks
Time frame: Baseline, Week 4, and Week 8
Change in Headache Disability Index (HDI) Score at Baseline, 4 Weeks, and 8 Weeks
Time frame: Baseline, Week 4, and Week 8
Change in Quality of Life Measured by Short Form-12 (SF-12) at Baseline, 4 Weeks, and 8 Weeks
Time frame: Baseline, Week 4, and Week 8
Change in Headache Frequency (Number of Headache Days per Month) at Baseline, 4 Weeks, and 8 Weeks
Time frame: Baseline, Week 4, and Week 8
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Nov 2025.
- Individual participant dataSharing planned: Yes. De-identified individual participant data (IPD) for all primary and secondary outcome measures (e.g., VAS, HIT-6, NDI, SF-12) will be made available to qualified researchers for secondary analysis. Data will be shared upon reasonable request, beginning 6 months after publication, for a period of 3 years. Access will be granted to researchers with methodologically sound proposals by contacting the Principal Investigator via institutional email.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Myofascial Release Group and Kinesiology Taping Group in people with Cervicogenic Headache, run by Konya Meram State Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Cervicogenic Headache Severity Measured by Visual Analog Scale (VAS) at Baseline, 4 Weeks, and 8 Weeks (time frame: Baseline, Week 4 (end of treatment), and Week 8 (1-month follow-up after treatment)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Nov 2025.