CancerNCT06943638
How Easy-to-Follow Exercises Can Help Cancer Patients With Anxiety While Receiving Chemotherapy
A study testing Mild Exercise and stretches in people with Cancer and Exercise, run by Christine Mavrogiannopoulou at 1 site in Greece.
Trial summary
Cancer is one of the main causes of death, and this study looks at how light exercise and stretching might reduce anxiety in patients receiving chemotherapy. The research took place in a hospital's daily care unit and used a study design where each patient was compared to themselves, measuring anxiety before and after… Read more about this study
- Who is it for?
- Ages 18 to 90 years
- What is being tested?
- Mild Exercise and stretches
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteGreece
- Study dates
- 2 Dec 2024to 24 Mar 2025
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 90 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adult patients (>18 years old) with cancer receiving chemotherapy
- Signed patient consent
Who cannot join
- The denial of the patient
- The occurrence of side effects from the treatment (such as dizziness, nausea, severe fatigue)
- Patients with low cognitive level where they could not follow simple instructions
- Patients with hearing disorders that prevented them from following simple instructions
- Patients who could not mobilize independently.
Trial locations and contacts
1 site in 1 country.
Greece1 site
General Oncological Hospital of Kifisia Oi Agioi Anargyroi
Athens, Kifissia, 14564
About this study
Official title: The Effect of Mild Exercise While Receiving Chemotherapy on the Psychology of the Cancer Patient
Cancer is one of the main causes of death, and this study looks at how light exercise and stretching might reduce anxiety in patients receiving chemotherapy. The research took place in a hospital's daily care unit and used a study design where each patient was compared to themselves, measuring anxiety before and after the exercise program.
- Being tested
- Mild Exercise and stretches
- Keywords
- cancer, physiotherapy, exercise, physical therapy, chemotherapy, stress
- Medical subject headings
- Neoplasms, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mild Exercise and stretchesOther
For 15 minutes the patient received an individualized mild workout program intending to relax and relieve some of his stress. The workout includes deep breaths, easy-to-do exercises, and stretches from lying on the bed, sitting in a chair, or standing. I always followed the patient's tempo and provided him with as many breaks as he needed.
| Study group | Role | What they receive |
|---|---|---|
| Mild exercise and stretching | Experimental | They received individualized workout and stretching programme to relieve some of the stress Receives: Other: Mild Exercise and stretches |
What is being measured
The primary outcome is the main question the study is designed to answer.
The Change in the Anxiety Assessment Scale (STAI-State) for Cancer Patients Receiving Chemotherapy Doing Mild Exercises and Stretches
The STAI-State (Greek version, State-Trait Anxiety Inventory -STAI-) will be used to assess anxiety levels in cancer patients undergoing chemotherapy, before and after a brief exercise intervention. The STAI-State scale has a 20-item questionnaire where individuals rate how they feel at a particular moment on a scale from "not at all" to "very much so." "Not at all" equal to 1, "Somewhat" to 2, "Moderately so" to 3, "Very much so" to 4. Scores are submitted and range from 20 to 80, with higher scores indicating greater anxiety. No subscale is required to compute At baseline (Time = 0 minutes), participants complete the STAI-State scale. They then engage in a 15-minute mild exercise and stretching program tailored to their physical condition. In some cases, particularly among younger participants, the session may be conducted in small groups of up to 2 individuals. Immediately post-intervention (approximately 20 minutes from baseline), participants complete the STAI-State scale again.
Measured: Baseline and approximately 20 minutes post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Apr 2025
- Study start2 Dec 2024
- Primary completion24 Mar 2025
- Study completion24 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Christine Mavrogiannopoulou
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Christine Mavrogiannopoulou, University of Crete
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06943638
- Sponsor's protocol ID
- 779/15-1-2024
- Status last verified
- Jul 2025
- First submitted
- 24 Mar 2025
- Last updated
- 1 Aug 2025
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: IPD will not be shared because this research doesn't require the reproduction of special types of patients. They need to have cancer, receive chemotherapy, and be adults.
Publications
Furmaniak AC, Menig M, Markes MH. Exercise for women receiving adjuvant therapy for breast cancer. Cochrane Database Syst Rev. 2016 Sep 21;9(9):CD005001. doi: 10.1002/14651858.CD005001.pub3.
PubMed 27650122Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvao DA, Pinto BM, Irwin ML, Wolin KY, Segal RJ, Lucia A, Schneider CM, von Gruenigen VE, Schwartz AL; American College of Sports Medicine. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010 Jul;42(7):1409-26. doi: 10.1249/MSS.0b013e3181e0c112.
PubMed 20559064
Study at a glance
From the registry record, last updated by the sponsor on 1 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Mild Exercise While Receiving Chemotherapy on the Psychology of the Cancer Patient
- ClinicalTrials.gov ID
- NCT06943638
- Acronym / sponsor ID
- 779/15-1-2024
- Keywords
- cancer, physiotherapy, exercise, physical therapy, chemotherapy, stress
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 45 participants (actual)
- Lead sponsor
- Christine MavrogiannopoulouUniversity, hospital or other
- Study start
- 2 Dec 2024 (actual)
- Primary completion
- 24 Mar 2025 (actual)
- Study completion
- 24 Mar 2025 (actual)
- First posted
- 24 Apr 2025 (actual)
- Results
- Posted 1 Aug 2025
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cancer is one of the main causes of death, and this study looks at how light exercise and stretching might reduce anxiety in patients receiving chemotherapy. The research took place in a hospital's daily care unit and used a study design where each patient was compared to themselves, measuring anxiety before and after the exercise program.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Mild exercise and stretching | Experimental | Other: Mild Exercise and stretchesThey received individualized workout and stretching programme to relieve some of the stress |
Who may qualify
- Ages
- 18 to 90 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Adult patients (>18 years old) with cancer receiving chemotherapy
- Signed patient consent
Key exclusion criteria (5 listed)
- The denial of the patient
- The occurrence of side effects from the treatment (such as dizziness, nausea, severe fatigue)
- Patients with low cognitive level where they could not follow simple instructions
- Patients with hearing disorders that prevented them from following simple instructions
- Patients who could not mobilize independently.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mild Exercise and stretchesFor 15 minutes the patient received an individualized mild workout program intending to relax and relieve some of his stress. The workout includes deep breaths, easy-to-do exercises, and stretches from lying on the bed, sitting in a chair, or standing. I always followed the patient's tempo and provided him with as many breaks as he needed. | Other | Mild exercise and stretching |
Primary outcome
The Change in the Anxiety Assessment Scale (STAI-State) for Cancer Patients Receiving Chemotherapy Doing Mild Exercises and Stretches
Time frame: Baseline and approximately 20 minutes post-intervention
The STAI-State (Greek version, State-Trait Anxiety Inventory -STAI-) will be used to assess anxiety levels in cancer patients undergoing chemotherapy, before and after a brief exercise intervention. The STAI-State scale has a 20-item questionnaire where individuals rate how they feel at a particular moment on a scale from "not at all" to "very much so." "Not at all" equal to 1, "Somewhat" to 2, "Moderately so" to 3, "Very much so" to 4. Scores are submitted and range from 20 to 80, with higher scores indicating greater anxiety. No subscale is required to compute At baseline (Time = 0 minutes), participants complete the STAI-State scale. They then engage in a 15-minute mild exercise and stretching program tailored to their physical condition. In some cases, particularly among younger participants, the session may be conducted in small groups of up to 2 individuals. Immediately post-intervention (approximately 20 minutes from baseline), participants complete the STAI-State scale again.
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Aug 2025.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Background: PubMed 27650122Furmaniak AC, Menig M, Markes MH. Exercise for women receiving adjuvant therapy for breast cancer. Cochrane Database Syst Rev. 2016 Sep 21;9(9):CD005001. doi: 10.1002/14651858.CD005001.pub3.
- Background: PubMed 20559064Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvao DA, Pinto BM, Irwin ML, Wolin KY, Segal RJ, Lucia A, Schneider CM, von Gruenigen VE, Schwartz AL; American College of Sports Medicine. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010 Jul;42(7):1409-26. doi: 10.1249/MSS.0b013e3181e0c112.
- Individual participant dataSharing planned: No. IPD will not be shared because this research doesn't require the reproduction of special types of patients. They need to have cancer, receive chemotherapy, and be adults.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mild Exercise and stretches in people with Cancer and Exercise, run by Christine Mavrogiannopoulou at 1 site in Greece.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Greece. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 1 Aug 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The Change in the Anxiety Assessment Scale (STAI-State) for Cancer Patients Receiving Chemotherapy Doing Mild Exercises and Stretches (time frame: Baseline and approximately 20 minutes post-intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06943638, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Aug 2025.