StrokeNCT06950749
Effects of Robotic Gloves Along With Task-oriented Mirror Therapy on Motor Functions of Hands in Sub-acute Stroke Patients
A study testing Robotic Gloves assisted Task-oriented mirror therapy and Task-Oriented Mirror Therapy in people with Stroke and Mirror Therapy, run by Foundation University Islamabad at 1 site in Pakistan.
Trial summary
This study is randomized control trial and purpose of this study is to find effects of robotic gloves assisted task-oriented mirror therapy in comparison with task-oriented mirror therapy on motor functions of hand in sub-acute stroke patients. Read more about this study
- Who is it for?
- Ages 40 years and older
- Conditions the study is for
- Stroke, Mirror Therapy, Robotics
- What is being tested?
- Robotic Gloves assisted Task-oriented mirror therapy and Task-Oriented Mirror Therapy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 sitePakistan
- Study dates
- 12 Oct 2024to 30 Apr 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 40 years and above.
- Ischemic (MCA) stroke.
- Male and females both.
- Montreal Cognitive Assessment (MoCA score >24 points).
- Motor power of proximal upper Extremity at least 3 with ability to reach out.
- FMA score for upper Extremity below 47
- Modified Ashworth spasticity score <2 in hands and finger joints.
- Ability to sit for at least 60 minutes
Who cannot join
- Musculoskeletal problems such as severe pain in any joints of the paretic upper extremity.
- Contractures in shoulder, elbow, hand or finger joints.
- Severe Visual impairments.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Foundation University College of Physical Therapy
Islamabad, 46000
About this study
This study is randomized control trial and purpose of this study is to find effects of robotic gloves assisted task-oriented mirror therapy in comparison with task-oriented mirror therapy on motor functions of hand in sub-acute stroke patients.
Read the detailed description
Motor functions of the hand involve different movements and activities that the hand can perform due to the coordination of different muscles group in everyday activities which involves dexterity, manipulative skills and task performance skills which includes grasp, release and different types of grips of hand.
RATIONALE:
While the mirror therapy has been studied extensively and literature provide good quality of evidence for effects of mirror therapy on motor functions of hands the integration of pneumatic Robotic Mirror Therapy is relatively less explored .
and there is no comparison between Task oriented MT and pneumatic Robotic Mirror Therapy
SIGNIFICANCE This study will increase the understanding and therapeutic potential of robotic gloves assisted task-oriented MT mirror therapy and will demonstrate its efficacy as beneficial interventions.
Modern devices like robotic gloves can potentially increase patient compliance by providing positive outcomes, setting goals and improving functional performance.
They can make therapy more engaging, interactive and help the patients track their progress, which can motivate them to adhere to their rehabilitation program.
HYPOTHESIS ALTERNATE HYPOTHESIS There will be a statistically significant difference in the effects of Task oriented Mirror Therapy in comparison with Robotic gloves Assisted task-oriented Mirror Therapy on motor functions of hand in patients with sub-acute Stroke (p<0.05).
NULL HYPOTHESIS There will be no statistically significant difference in the effects of Task oriented Mirror Therapy in comparison with Robotic gloves Assisted task-oriented Mirror Therapy on motor functions of hand in patients with sub-acute Stroke (p>0.05).
- Conditions
- Stroke, Mirror Therapy, Robotics, Neurorehabilitation
- Being tested
- Robotic Gloves assisted Task-oriented mirror therapy, Task-Oriented Mirror Therapy
- Keywords
- stroke, mirror therapy, robotics, neurorehabilitation
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Robotic Gloves assisted Task-oriented mirror therapyProcedure or surgery
Robotic gloves assissted task-oriented Mirror therapy along with conventional therapy.
Conventional therapy consists of stretching exercises,active assisted and active ROMS of shoulder along with weight bearing and reaching activities.
Robotic gloves assisted task-oriented Mirror therapy will be delivered by syrebo robotic hand rehabilitation device.
it has different training modes including Mirror mode and task-oriented training.
5 sessions per week will be provided for 8 weeks exercises: 30 minutes (3 sets of 10 reps)
- In mirror training mode: Synchronized flexion and extension training with both hands.
Task-Oriented Mirror TherapyProcedure or surgery
Interventional group (B) will receive Task-Oriented Mirror Therapy along with conventional therapy.
To perform Task-Oriented Mirror Therapy both the extremities of the subject will be placed on the table and the mirror (40×60 cm) will be placed in the patients' mid-sagittal plane. Mirror will be placed in such a way that the reflection of the non-affected arm can be seen. The subjects will be instructed to perform the movement bilaterally. The movement on the impaired limb will be performed. Affected arm is involved in exercise therapy either through patients trying to move themselves or with a therapist in assisting movement.
5 sessions per week will be provided for 8 weeks.
- Task-Oriented Mirror therapy exercises: 30 minutes. (3 sets of 10 reps)
- Hand flexion and extension through the tennis ball.
- Grasping and releasing (cylindrical grasp, spherical grasp, hook grasp, pincer grasp)
- Task oriented activities: positioning the cup upright, carrying a woode
| Study group | Role | What they receive |
|---|---|---|
| INTERVENTION GROUP (A) | Experimental | INTERVENTION GROUP (A) will receive Robotic Gloves Assisted Task-Oriented Mirror Therapy along with conventional therapy.
subjects will sit on a chair and placed their both hands on the table. Patients will wear the soft robotic glove on affected hand and the data glove the unaffected hand.
Subjects will be instructed to visually observe the hand being moved by soft robotic glove
* In mirror training mode: Synchronized flexion and extension training with both hands.
* Task oriented activities: With help of robot patient will practice grasping, releasing the tennis ball, positioning the cup upright, carrying a wooded block, putting a ball Receives: Procedure: Robotic Gloves assisted Task-oriented mirror therapy |
| INTERVENTIONAL GROUP (B) | Experimental | INTERVENTIONAL GROUP (B) will receive Task-Oriented Mirror Therapy along with conventional therapy.
Both the extremities of the subject will be placed on the table and mirror will be placed in the patients' mid sagittal plane. Mirror will be placed in such a way that the reflection of the non-affected arm to be seen.
* Grasping and releasing (cylindrical grasp, spherical grasp, hook grasp, pincer grasp)
* Task oriented activities: positioning the cup upright, carrying a wooded block and putting a ball. Receives: Procedure: Task-Oriented Mirror Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
hand motor functions
Fugl Meyer Assessment (FMA-UE), wii be used to assess motor functions of hands FMA:used to measure motor recovery in stroke patients. it has a maximum score of 66 points FMA hand section will be used to assess motor functions of hands from baseline to end of interventions.
Measured: 08 Weeks
Dexterity
An action research arm test will be used. Scores were rated on a 4-point scale, ranging from 0 (no movement) to 3 (movement performed normally) for a maximum score of 57.
Measured: 8 weeks
unilateral gross manual dexterity
Box and block test is used to assess the unilateral gross manual dexterity of the hand. Subjects will be asked to move a wooden block from one compartment to the other.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Apr 2025
- Study start12 Oct 2024
- Primary completion15 Mar 2025
- Study completion30 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Foundation University IslamabadThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Foundation University Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06950749
- Sponsor's protocol ID
- FUI/CTR/2024/50
- Status last verified
- Jul 2026
- First submitted
- 14 Nov 2024
- Last updated
- 29 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Robotic Gloves Along With Task-oriented Mirror Therapy on Motor Functions of Hands in Sub-acute Stroke Patients
- ClinicalTrials.gov ID
- NCT06950749
- Acronym / sponsor ID
- FUI/CTR/2024/50
- Conditions
- Stroke, Mirror Therapy, Robotics, Neurorehabilitation
- Keywords
- stroke, mirror therapy, robotics, neurorehabilitation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Foundation University IslamabadUniversity, hospital or other
- Study start
- 12 Oct 2024 (actual)
- Primary completion
- 15 Mar 2025 (actual)
- Study completion
- 30 Apr 2025 (actual)
- First posted
- 30 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is randomized control trial and purpose of this study is to find effects of robotic gloves assisted task-oriented mirror therapy in comparison with task-oriented mirror therapy on motor functions of hand in sub-acute stroke patients.
Detailed description
Motor functions of the hand involve different movements and activities that the hand can perform due to the coordination of different muscles group in everyday activities which involves dexterity, manipulative skills and task performance skills which includes grasp, release and different types of grips of hand.
RATIONALE:
While the mirror therapy has been studied extensively and literature provide good quality of evidence for effects of mirror therapy on motor functions of hands the integration of pneumatic Robotic Mirror Therapy is relatively less explored .
and there is no comparison between Task oriented MT and pneumatic Robotic Mirror Therapy
SIGNIFICANCE This study will increase the understanding and therapeutic potential of robotic gloves assisted task-oriented MT mirror therapy and will demonstrate its efficacy as beneficial interventions.
Modern devices like robotic gloves can potentially increase patient compliance by providing positive outcomes, setting goals and improving functional performance.
They can make therapy more engaging, interactive and help the patients track their progress, which can motivate them to adhere to their rehabilitation program.
HYPOTHESIS ALTERNATE HYPOTHESIS There will be a statistically significant difference in the effects of Task oriented Mirror Therapy in comparison with Robotic gloves Assisted task-oriented Mirror Therapy on motor functions of hand in patients with sub-acute Stroke (p<0.05).
NULL HYPOTHESIS There will be no statistically significant difference in the effects of Task oriented Mirror Therapy in comparison with Robotic gloves Assisted task-oriented Mirror Therapy on motor functions of hand in patients with sub-acute Stroke (p>0.05).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| INTERVENTION GROUP (A) | Experimental | Procedure: Robotic Gloves assisted Task-oriented mirror therapyINTERVENTION GROUP (A) will receive Robotic Gloves Assisted Task-Oriented Mirror Therapy along with conventional therapy. subjects will sit on a chair and placed their both hands on the table. Patients will wear the soft robotic glove on affected hand and the data glove the unaffected hand. Subjects will be instructed to visually observe the hand being moved by soft robotic glove * In mirror training mode: Synchronized flexion and extension training with both hands. * Task oriented activities: With help of robot patient will practice grasping, releasing the tennis ball, positioning the cup upright, carrying a wooded block, putting a ball |
| INTERVENTIONAL GROUP (B) | Experimental | Procedure: Task-Oriented Mirror TherapyINTERVENTIONAL GROUP (B) will receive Task-Oriented Mirror Therapy along with conventional therapy. Both the extremities of the subject will be placed on the table and mirror will be placed in the patients' mid sagittal plane. Mirror will be placed in such a way that the reflection of the non-affected arm to be seen. * Grasping and releasing (cylindrical grasp, spherical grasp, hook grasp, pincer grasp) * Task oriented activities: positioning the cup upright, carrying a wooded block and putting a ball. |
Who may qualify
- Ages
- 40 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- 40 years and above.
- Ischemic (MCA) stroke.
- Male and females both.
- Montreal Cognitive Assessment (MoCA score >24 points).
- Motor power of proximal upper Extremity at least 3 with ability to reach out.
Key exclusion criteria (3 listed)
- Musculoskeletal problems such as severe pain in any joints of the paretic upper extremity.
- Contractures in shoulder, elbow, hand or finger joints.
- Severe Visual impairments.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Robotic Gloves assisted Task-oriented mirror therapyRobotic gloves assissted task-oriented Mirror therapy along with conventional therapy. Conventional therapy consists of stretching exercises,active assisted and active ROMS of shoulder along with weight bearing and reaching activities. Robotic gloves assisted task-oriented Mirror therapy will be delivered by syrebo robotic hand rehabilitation device. it has different training modes including Mirror mode and task-oriented training. 5 sessions per week will be provided for 8 weeks exercises: 30 minutes (3 sets of 10 reps) * In mirror training mode: Synchronized flexion and extension training with both hands. | Procedure or surgery | INTERVENTION GROUP (A) |
| Task-Oriented Mirror TherapyInterventional group (B) will receive Task-Oriented Mirror Therapy along with conventional therapy. To perform Task-Oriented Mirror Therapy both the extremities of the subject will be placed on the table and the mirror (40×60 cm) will be placed in the patients' mid-sagittal plane. Mirror will be placed in such a way that the reflection of the non-affected arm can be seen. The subjects will be instructed to perform the movement bilaterally. The movement on the impaired limb will be performed. Affected arm is involved in exercise therapy either through patients trying to move themselves or with a therapist in assisting movement. 5 sessions per week will be provided for 8 weeks. * Task-Oriented Mirror therapy exercises: 30 minutes. (3 sets of 10 reps) * Hand flexion and extension through the tennis ball. * Grasping and releasing (cylindrical grasp, spherical grasp, hook grasp, pincer grasp) * Task oriented activities: positioning the cup upright, carrying a woode | Procedure or surgery | INTERVENTIONAL GROUP (B) |
Primary outcome
hand motor functions
Time frame: 08 Weeks
Fugl Meyer Assessment (FMA-UE), wii be used to assess motor functions of hands FMA:used to measure motor recovery in stroke patients. it has a maximum score of 66 points FMA hand section will be used to assess motor functions of hands from baseline to end of interventions.
Dexterity
Time frame: 8 weeks
An action research arm test will be used. Scores were rated on a 4-point scale, ranging from 0 (no movement) to 3 (movement performed normally) for a maximum score of 57.
unilateral gross manual dexterity
Time frame: 8 weeks
Box and block test is used to assess the unilateral gross manual dexterity of the hand. Subjects will be asked to move a wooden block from one compartment to the other.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Robotic Gloves assisted Task-oriented mirror therapy and Task-Oriented Mirror Therapy in people with Stroke and Mirror Therapy, run by Foundation University Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
hand motor functions (time frame: 08 Weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2026.