Pemphigus VulgarisNCT06971172
Low-level Laser Therapy on Oral Pemphigus Vulgaris Patients.
A study testing Low energy diode Laser and Medication in people with Pemphigus Vulgaris, run by Cairo University.
Trial summary
To assess the therapeutic efficacy of low level laser therapy on oral pemphigus vulgaris patients. Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Pemphigus Vulgaris
- What is being tested?
- Low energy diode Laser and Medication
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 22 participants
- Where
- No sites listed yet
- Study dates
- 1 Jun 2025to 1 Sep 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients with oral pemphigus vulgaris
Who cannot join
- other causes of oral ulcers
About this study
Official title: EFFECT OF LOW LEVEL LASER THERAPY ON ORAL PIMPHIGUS VULGARIS
To assess the therapeutic efficacy of low level laser therapy on oral pemphigus vulgaris patients.
- Conditions
- Pemphigus Vulgaris
- Being tested
- Low energy diode Laser, Medication
- Medical subject headings
- Pemphigus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Low energy diode LaserDevice
Diode Laser
MedicationDrug
pulse steriod therapy and immunosuppressive drugs
| Study group | Role | What they receive |
|---|---|---|
| Low energy laser plus medical treatment | Experimental | Device Receives: Device: Low energy diode Laser |
| Medical treatment | Active comparator | Medical treatment Receives: Drug: Medication |
What is being measured
The primary outcome is the main question the study is designed to answer.
wound margins in millimeters
Measurement
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 May 2025
- Study start1 Jun 2025 (estimated)
- Primary completion1 Jul 2025 (estimated)
- Study completion1 Sep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pemphigus VulgarisStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 22 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hagar El Sayed, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06971172
- Sponsor's protocol ID
- low energy laser in pemphigus
- Status last verified
- May 2025
- First submitted
- 8 Dec 2024
- Last updated
- 14 May 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- EFFECT OF LOW LEVEL LASER THERAPY ON ORAL PIMPHIGUS VULGARIS
- ClinicalTrials.gov ID
- NCT06971172
- Acronym / sponsor ID
- low energy laser in pemphigus
- Conditions
- Pemphigus Vulgaris
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 22 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 1 Jul 2025 (estimated)
- Study completion
- 1 Sep 2025 (estimated)
- First posted
- 14 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To assess the therapeutic efficacy of low level laser therapy on oral pemphigus vulgaris patients.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Low energy laser plus medical treatment | Experimental | Device: Low energy diode LaserDevice |
| Medical treatment | Active comparator | Drug: MedicationMedical treatment |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Patients with oral pemphigus vulgaris
Key exclusion criteria (1 listed)
- other causes of oral ulcers
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Low energy diode LaserDiode Laser | Device | Low energy laser plus medical treatment |
| Medicationpulse steriod therapy and immunosuppressive drugs | Drug | Medical treatment |
Primary outcome
wound margins in millimeters
Time frame: 1 month
Measurement
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 May 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Low energy diode Laser and Medication in people with Pemphigus Vulgaris, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 May 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
wound margins in millimeters (time frame: 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 May 2025.