Anesthesia for Hip SurgeryNCT06993376
PENG Block vs ESPB in Elderly Undergoing Hip Surgeries
A study testing PENG block and ESPB in people with Anesthesia for Hip Surgery, run by Cairo University.
Trial summary
To our knowledge, the comparison between the ultrasound-guided lumbar erector spinae plane block and the pericapsular nerve group block has not been investigated before in previous literature. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Anesthesia for Hip Surgery
- What is being tested?
- PENG block and ESPB
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 56 participants
- Where
- No sites listed yet
- Study dates
- 1 Jun 2025to 1 Dec 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Who may be able to join
- Both genders Type of surgery; unilateral elective total hip replacement. Physical status ASA I, II Age more than or equal 65 Years. Body mass index (BMI): > 20 kg/m2 and < 35 kg/m2.
Who cannot join
- Patient refusal. Patients with known sensitivity or contraindication to drugs used in the study (local anesthetics \& opioids).
- History of psychological disorders and/or chronic pain. Pre- existing peripheral neuropathies Coagulopathy. Infection of the skin at the site of needle puncture area.
About this study
Official title: Comparison Between the Ultrasound Guided Pericapsular Nerve Group Block and Erector Spinae Plane Block on Motor Power Postoperative in Elderly Patients Undergoing Total Hip Replacement Surgeries; A Randomized Controlled Trial
To our knowledge, the comparison between the ultrasound-guided lumbar erector spinae plane block and the pericapsular nerve group block has not been investigated before in previous literature.
- Conditions
- Anesthesia for Hip Surgery
- Being tested
- PENG block, ESPB
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
PENG blockProcedure or surgery
Group LESBP: 28 patients will receive single shot LESPB after spinal induction. Group PENG: 28 patients will receive single shot PENG after spinal induction.
ESPBProcedure or surgery
Group LESBP: 28 patients will receive single shot LESPB after spinal induction. Group PENG: 28 patients will receive single shot PENG after spinal induction.
| Study group | Role | What they receive |
|---|---|---|
| PENG block | Active comparator | Not described Receives: Procedure: PENG block |
| ESPb | Active comparator | Not described Receives: Procedure: ESPB |
What is being measured
The primary outcome is the main question the study is designed to answer.
Motor power
The result of substraction of VAS from MRC at ipsilateral lower limb at the time of regaining of full motor power in the contralateral lower limb (delta).
Measured: 24 hours postoperative
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 May 2025
- Study start1 Jun 2025 (estimated)
- Primary completion1 Nov 2025 (estimated)
- Study completion1 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anesthesia for Hip SurgeryStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 56 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, mohamed abdelghany ali, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06993376
- Sponsor's protocol ID
- N22-2023/MD
- Status last verified
- May 2025
- First submitted
- 19 May 2025
- Last updated
- 29 May 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 29 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison Between the Ultrasound Guided Pericapsular Nerve Group Block and Erector Spinae Plane Block on Motor Power Postoperative in Elderly Patients Undergoing Total Hip Replacement Surgeries; A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06993376
- Acronym / sponsor ID
- N22-2023/MD
- Conditions
- Anesthesia for Hip Surgery
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 56 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 1 Nov 2025 (estimated)
- Study completion
- 1 Dec 2025 (estimated)
- First posted
- 28 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To our knowledge, the comparison between the ultrasound-guided lumbar erector spinae plane block and the pericapsular nerve group block has not been investigated before in previous literature.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| PENG block | Active comparator | Procedure: PENG block |
| ESPb | Active comparator | Procedure: ESPB |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (1 listed)
- Both genders Type of surgery; unilateral elective total hip replacement. Physical status ASA I, II Age more than or equal 65 Years. Body mass index (BMI): > 20 kg/m2 and < 35 kg/m2.
Key exclusion criteria (2 listed)
- Patient refusal. Patients with known sensitivity or contraindication to drugs used in the study (local anesthetics \& opioids).
- History of psychological disorders and/or chronic pain. Pre- existing peripheral neuropathies Coagulopathy. Infection of the skin at the site of needle puncture area.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| PENG blockGroup LESBP: 28 patients will receive single shot LESPB after spinal induction. Group PENG: 28 patients will receive single shot PENG after spinal induction. | Procedure or surgery | PENG block |
| ESPBGroup LESBP: 28 patients will receive single shot LESPB after spinal induction. Group PENG: 28 patients will receive single shot PENG after spinal induction. | Procedure or surgery | ESPb |
Primary outcome
Motor power
Time frame: 24 hours postoperative
The result of substraction of VAS from MRC at ipsilateral lower limb at the time of regaining of full motor power in the contralateral lower limb (delta).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 May 2025.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing PENG block and ESPB in people with Anesthesia for Hip Surgery, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 29 May 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Motor power (time frame: 24 hours postoperative). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 May 2025.