HypotensionJUSHNCT07000188
Jugular Ultrasound for Spinal Hypotension
An observational study of Hypotension and Anesthesia, Spinal, run by Cairo University at 1 site in Egypt.
Trial summary
Spinal induced hypotension is common complication in geriatric group of patient with percentage up to 73% among these group]. the most common causes that enhance occurrence of post spinal anesthesia induced hypotension among elderly are poor physical condition , chronic systemic diseases , medications and long fasting… Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Hypotension, Anesthesia, Spinal, Aged
- How many people
- 70 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Jul 2025to 3 Mar 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: elderly patients equal or more than 65 years old
Who may be able to join
- • Age > 65 years old.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I, II , III.
- Elective surgeries Under spinal anesthesia in the supine position.
Who cannot join
- • Body Mass Index (BMI) more than 35 kg/m2.
- Uncontrolled hypertension.
- Ejection fraction less than 40%
- Emergency cases.
- Absolute or relative contraindications to spinal anesthesia.
- Patients with a baseline arterial systolic blood pressure (SBP) less than 90 mmHg or mean arterial blood pressure (MBP) less than 65 mmHg.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Preoperative Ultrasonographic Assesment of the Internal Jugular Vein to Predict Post Spinal Hypotension in Elderly Patients, Observational Study
Spinal induced hypotension is common complication in geriatric group of patient with percentage up to 73% among these group]. the most common causes that enhance occurrence of post spinal anesthesia induced hypotension among elderly are poor physical condition , chronic systemic diseases , medications and long fasting time, intraoperative hypotension if severe or prolonged is associated with hazardous complication such as myocardial infarction , stroke, renal failure and perioperative mortality ,so accurate assessment of intravascular volume before induction of anesthesia is necessary to limit these hazards.
Various studies had reported that ultrasonographic measurements of inferior vena cava collapsibility index is a good predictor for reflexing the intravascular volume status[5][6] , this is non invasive , on the other hand IVC is not easily feasible in obese and pregnant women.
Read more
Some studies compared the difference between IVC and IJV as predictor marker for fluid responsiveness and reported that right internal jugular vein distensibility appears to be a surrogate marker for inferior vena cava vein distensibility for evaluating fluid responsiveness.
Almost great percentage of anesthesiologist easily use IJV ultrasonography for catheterization and it is easily feasible in almost all patients, recent studies documented that noninvasive ultrasonographic measurements of internal jagular vein diameter has a role in assessment of intravascular volume status in spontaneously and mechanically breathing patients, Passive leg raising has been shown to be useful in assessing intravascular volume depletion or fluid responsiveness , some studies compared IJV changing in diameter for supine and trendelenburg positions, there is a similar change in IJV diameter will occur with passive leg raising positions , trendelenburg position may be disadvantageous as it impair gas function and cardiac function especially in elderly and obese patients , on the other hand passive leg raising is simpler and more comfortable to the elderly.
Finally preoperative detection of decreased intravascular volume is crucial in elderly patients, so we hypothesized that preoperative ultrasonographic evaluation of the internal jagular vein measurements may be a reliable tool for estimating intravascular volume and prediction of post spinal hypotension in elderly.
- Conditions
- Hypotension, Anesthesia, Spinal, Aged
- Keywords
- spinal anesthesia, elderly, hypotension, ultrasound, passive leg raising, IJV
- Medical subject headings
- Hypotension
What is being measured
The primary outcome is the main question the study is designed to answer.
• The accuracy of ultrasonographic changes in IJV area with positions (supine and PLR) in predicting spinal hypotension in geriatric patients.
Measured: time needed to spinal anesthesia related hypotension occurs which arround 20 to 30 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Jun 2025
- Study start10 Jul 2025
- Primary completion20 Feb 2026
- Study completion3 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HypotensionStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mai younes Taha, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07000188
- Sponsor's protocol ID
- ANES -IJV U/S 2025
- Acronym
- JUSH
- Status last verified
- Mar 2026
- First submitted
- 23 May 2025
- Last updated
- 10 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 10 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Preoperative Ultrasonographic Assesment of the Internal Jugular Vein to Predict Post Spinal Hypotension in Elderly Patients, Observational Study
- ClinicalTrials.gov ID
- NCT07000188
- Acronym / sponsor ID
- JUSH / ANES -IJV U/S 2025
- Conditions
- Hypotension, Anesthesia, Spinal, Aged
- Keywords
- spinal anesthesia, elderly, hypotension, ultrasound, passive leg raising, IJV
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 10 Jul 2025 (actual)
- Primary completion
- 20 Feb 2026 (actual)
- Study completion
- 3 Mar 2026 (actual)
- First posted
- 2 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Spinal induced hypotension is common complication in geriatric group of patient with percentage up to 73% among these group]. the most common causes that enhance occurrence of post spinal anesthesia induced hypotension among elderly are poor physical condition , chronic systemic diseases , medications and long fasting time, intraoperative hypotension if severe or prolonged is associated with hazardous complication such as myocardial infarction , stroke, renal failure and perioperative mortality ,so accurate assessment of intravascular volume before induction of anesthesia is necessary to limit these hazards.
Various studies had reported that ultrasonographic measurements of inferior vena cava collapsibility index is a good predictor for reflexing the intravascular volume status[5][6] , this is non invasive , on the other hand IVC is not easily feasible in obese and pregnant women.
Some studies compared the difference between IVC and IJV as predictor marker for fluid responsiveness and reported that right internal jugular vein distensibility appears to be a surrogate marker for inferior vena cava vein distensibility for evaluating fluid responsiveness.
Almost great percentage of anesthesiologist easily use IJV ultrasonography for catheterization and it is easily feasible in almost all patients, recent studies documented that noninvasive ultrasonographic measurements of internal jagular vein diameter has a role in assessment of intravascular volume status in spontaneously and mechanically breathing patients, Passive leg raising has been shown to be useful in assessing intravascular volume depletion or fluid responsiveness , some studies compared IJV changing in diameter for supine and trendelenburg positions, there is a similar change in IJV diameter will occur with passive leg raising positions , trendelenburg position may be disadvantageous as it impair gas function and cardiac function especially in elderly and obese patients , on the other hand passive leg raising is simpler and more comfortable to the elderly.
Finally preoperative detection of decreased intravascular volume is crucial in elderly patients, so we hypothesized that preoperative ultrasonographic evaluation of the internal jagular vein measurements may be a reliable tool for estimating intravascular volume and prediction of post spinal hypotension in elderly.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- elderly patients equal or more than 65 years old
Key inclusion criteria (4 listed)
- • Age > 65 years old.
Key exclusion criteria (6 listed)
- • Body Mass Index (BMI) more than 35 kg/m2.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
• The accuracy of ultrasonographic changes in IJV area with positions (supine and PLR) in predicting spinal hypotension in geriatric patients.
Time frame: time needed to spinal anesthesia related hypotension occurs which arround 20 to 30 minutes
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hypotension and Anesthesia, Spinal, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 10 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
• The accuracy of ultrasonographic changes in IJV area with positions (supine and PLR) in predicting spinal hypotension in geriatric patients. (time frame: time needed to spinal anesthesia related hypotension occurs which arround 20 to 30 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Mar 2026.