Blood PressureNCT07002307
The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters
A study testing Warm water at 35 oC, Coffee and Honey-sweetened coffee in people with Blood Pressure and Heart Rate, run by University of Uyo Teaching Hospital at 1 site in Nigeria.
Trial summary
The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose. Read more about this study
- Who is it for?
- Ages 18 to 26 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Blood Pressure, Heart Rate, Blood Glucose
- What is being tested?
- Warm water at 35 oC, Coffee and Honey-sweetened coffee
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 70 participants
- Where
- 1 siteNigeria
- Study dates
- 17 Oct 2023to 19 Oct 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 26 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age between 18 and 26
- Non-habitual coffee and tea drinkers who consume coffee, green tea, or black tea 2-5 times in the last two months
- Non-allergic to coffee, green tea, black tea, or honey
- Absence of medication use
- Will refrain from ingesting energy drinks, carbonated beverages, caffeinated beverages, or food for 24 hours before the study and throughout the study periods
- Will not consume anything except water after 11 p.m. during the experimental days Will be available and cooperate throughout the study duration.
Who cannot join
- Presence of cardiovascular disorders, hypertension, or diabetes
- Blood pressure above 120/80 mmHg and random blood glucose above 125 mg/dL
- Alcohol intake
- Smoking
- Habitual coffee or tea drinker
Trial locations and contacts
1 site in 1 country.
Nigeria1 site
Physiology laboratory, Physiology Department, Faculty of Basic Medical Sciences, University of Uyo
Uyo, Akwa Ibom State, 520003
About this study
Official title: The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Blood Pressure, Heart Rate and Blood Glucose
The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose. The main questions it aims to answer are:
Does honey-sweetened black tea, green tea, and coffee, respectively, have the ability to influence blood pressure, heart rate, or blood glucose level?
Read more
Research will compare honey-sweetened black tea, green tea, and coffee to a placebo (warm water) to see if honey-sweetened black tea, green tea, and coffee work to reduce or increase blood pressure, heart rate, or blood glucose.
Participants will:
Take honey-sweetened black tea, green tea, and coffee, OR plain black tea, green tea, and coffee, OR warm water, one cup a day for 3 days The beverages will be taken at the Physiology laboratory, University of Uyo, and the participants will be observed for 60 minutes, during which their blood pressure, heart rate, and blood glucose level will be measured. This procedure will be repeated for the 3 days of study.
- Conditions
- Blood Pressure, Heart Rate, Blood Glucose
- Being tested
- Warm water at 35 oC, Coffee, Honey-sweetened coffee, Green tea, Honey-sweetened green tea
- Keywords
- Coffee, Honey-sweetened coffee, Black tea, Honey-sweetened black tea, Green Tea, Honey-sweetened green tea, Blood pressure, Heart rate, Blood glucose
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Warm water at 35 oCOther
The placebo for the control group
CoffeeOther
Instant coffee, Nescafé Gold Blend, manufactured by Nestlé Coffee Brand, Nestlé Global
Honey-sweetened coffeeOther
Instant coffee plus raw dark amber honey produced by Apis mellifera adansonii
Green teaOther
Qualitea Natural Green Tea, packed by Qualitea Ceylon (PVT) LTD
Honey-sweetened green teaOther
Green tea plus honey
Black teaOther
Lipton Yellow Label Black Tea
Honey-sweetened black teaOther
Black tea plus honey
| Study group | Role | What they receive |
|---|---|---|
| Control group | Placebo comparator | Will receive 250 mL of warm water Receives: Other: Warm water at 35 oC |
| Coffee group | Active comparator | Will receive 2.25 g of coffee dissolved in 250 mL of hot water Receives: Other: Coffee |
| Honey-sweetened coffee group | Active comparator | Will receive 2.25 g of coffee plus 20 mL of honey put in 250 mL of hot water Receives: Other: Honey-sweetened coffee |
| Green tea group | Active comparator | Will receive 2 g of green tea infuse in 250 mL of hot water Receives: Other: Green tea |
| Honey-sweetened green tea group | Active comparator | Will receive 2 g of green tea plus 250 mL of honey put in 250 mL of hot water Receives: Other: Honey-sweetened green tea |
| Black tea group | Active comparator | Will receive 2 g of black tea infuse in 250 mL of hot water Receives: Other: Black tea |
| Honey-sweetened black tea group | Active comparator | Will receive 2 g of black tea plus 20 mL of honey put in 250 mL of hot water Receives: Other: Honey-sweetened black tea |
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood pressure
Measured: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
Heart rate
Measured: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
Blood glucose
Measured: Will be measured before consumption of the beverages and at 30 and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
Secondary outcomes (3)
Age
Measured: Will obtained during the eligibility process
Height
Measured: Will be measured on the first day of the experiment before the commencement of the experiment.
Body weight
Measured: Measurements will be taken over the course of the 3-day study prior to the commencement of the experiment each day.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2025
- Study start17 Oct 2023
- Primary completion19 Oct 2023
- Study completion19 Oct 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Blood PressureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Uyo Teaching Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Esther Oluwasola Aluko, University of Uyo Teaching Hospital
- Investigators
- Esther O Aluko, Principal investigator, University of Uyo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07002307
- Sponsor's protocol ID
- Uuthuyo
- Status last verified
- Jun 2025
- First submitted
- 23 May 2025
- Last updated
- 15 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Blood Pressure, Heart Rate and Blood Glucose
- ClinicalTrials.gov ID
- NCT07002307
- Acronym / sponsor ID
- Uuthuyo
- Conditions
- Blood Pressure, Heart Rate, Blood Glucose
- Keywords
- Coffee, Honey-sweetened coffee, Black tea, Honey-sweetened black tea, Green Tea, Honey-sweetened green tea, Blood pressure, Heart rate
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- University of Uyo Teaching HospitalUniversity, hospital or other
- Study start
- 17 Oct 2023 (actual)
- Primary completion
- 19 Oct 2023 (actual)
- Study completion
- 19 Oct 2023 (actual)
- First posted
- 3 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose. The main questions it aims to answer are:
Does honey-sweetened black tea, green tea, and coffee, respectively, have the ability to influence blood pressure, heart rate, or blood glucose level?
Research will compare honey-sweetened black tea, green tea, and coffee to a placebo (warm water) to see if honey-sweetened black tea, green tea, and coffee work to reduce or increase blood pressure, heart rate, or blood glucose.
Participants will:
Take honey-sweetened black tea, green tea, and coffee, OR plain black tea, green tea, and coffee, OR warm water, one cup a day for 3 days The beverages will be taken at the Physiology laboratory, University of Uyo, and the participants will be observed for 60 minutes, during which their blood pressure, heart rate, and blood glucose level will be measured. This procedure will be repeated for the 3 days of study.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 7
| Arm | Type | Receives |
|---|---|---|
| Control group | Placebo comparator | Other: Warm water at 35 oCWill receive 250 mL of warm water |
| Coffee group | Active comparator | Other: CoffeeWill receive 2.25 g of coffee dissolved in 250 mL of hot water |
| Honey-sweetened coffee group | Active comparator | Other: Honey-sweetened coffeeWill receive 2.25 g of coffee plus 20 mL of honey put in 250 mL of hot water |
| Green tea group | Active comparator | Other: Green teaWill receive 2 g of green tea infuse in 250 mL of hot water |
| Honey-sweetened green tea group | Active comparator | Other: Honey-sweetened green teaWill receive 2 g of green tea plus 250 mL of honey put in 250 mL of hot water |
| Black tea group | Active comparator | Other: Black teaWill receive 2 g of black tea infuse in 250 mL of hot water |
| Honey-sweetened black tea group | Active comparator | Other: Honey-sweetened black teaWill receive 2 g of black tea plus 20 mL of honey put in 250 mL of hot water |
Who may qualify
- Ages
- 18 to 26 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Age between 18 and 26
- Non-habitual coffee and tea drinkers who consume coffee, green tea, or black tea 2-5 times in the last two months
- Non-allergic to coffee, green tea, black tea, or honey
- Absence of medication use
- Will refrain from ingesting energy drinks, carbonated beverages, caffeinated beverages, or food for 24 hours before the study and throughout the study periods
Key exclusion criteria (5 listed)
- Presence of cardiovascular disorders, hypertension, or diabetes
- Blood pressure above 120/80 mmHg and random blood glucose above 125 mg/dL
- Alcohol intake
- Smoking
- Habitual coffee or tea drinker
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Warm water at 35 oCThe placebo for the control group | Other | Control group |
| CoffeeInstant coffee, Nescafé Gold Blend, manufactured by Nestlé Coffee Brand, Nestlé Global | Other | Coffee group |
| Honey-sweetened coffeeInstant coffee plus raw dark amber honey produced by Apis mellifera adansonii | Other | Honey-sweetened coffee group |
| Green teaQualitea Natural Green Tea, packed by Qualitea Ceylon (PVT) LTD | Other | Green tea group |
| Honey-sweetened green teaGreen tea plus honey | Other | Honey-sweetened green tea group |
| Black teaLipton Yellow Label Black Tea | Other | Black tea group |
| Honey-sweetened black teaBlack tea plus honey | Other | Honey-sweetened black tea group |
Primary outcome
Blood pressure
Time frame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
Heart rate
Time frame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
Blood glucose
Time frame: Will be measured before consumption of the beverages and at 30 and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
3 secondary outcomes
Age
Time frame: Will obtained during the eligibility process
Height
Time frame: Will be measured on the first day of the experiment before the commencement of the experiment.
Body weight
Time frame: Measurements will be taken over the course of the 3-day study prior to the commencement of the experiment each day.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jun 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Esther O Aluko principal investigator
University of Uyo
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Warm water at 35 oC, Coffee and Honey-sweetened coffee in people with Blood Pressure and Heart Rate, run by University of Uyo Teaching Hospital at 1 site in Nigeria.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Nigeria. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Blood pressure (time frame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jun 2025.