Flu-like SyndromeNCT07007377
Can the Ergometric Test in Flu-like Syndrome Help in the Outcome Analysis of Unvaccinated Patients
An observational study of Flu-like Syndrome and FLU, run by University of Sao Paulo at 1 site in Brazil.
Trial summary
During the flu-like syndrome, the cardiovascular risk is increased, especially in the elderly. Understanding whether blood pressure assessment during an exercise test can aid in the understanding of patient outcomes, thereby improving prognostic ability in clinical practice, is the focus of the present study. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Flu-like Syndrome, FLU, Flu-like Symptoms
- What is being tested?
- Follow-up
- Type of treatment
- Vaccines
- How many people
- 62 participants
- Where
- 1 siteBrazil
- Study dates
- 1 Apr 2025to 5 Dec 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Adults with flu symptoms, which were vaccinated or not.
Who may be able to join
- flu-symptoms
Who cannot join
- recent orthopedic surgery
Trial locations and contacts
1 site in 1 country.
About this study
During the flu-like syndrome, the cardiovascular risk is increased, especially in the elderly. Understanding whether blood pressure assessment during an exercise test can aid in the understanding of patient outcomes, thereby improving prognostic ability in clinical practice, is the focus of the present study. Therefore, the aim of this study is to evaluate the hemodynamic response of adults with flu-like symptoms, both vaccinated and unvaccinated, and to conduct a 30-day follow-up for assessment. Patients who are indicated for an ergometric test and present with flu-like syndrome will be selected. We will inquire about their vaccination history and perform the ergometric test to evaluate test duration, arrhythmias, and ischemias
- Conditions
- Flu-like Syndrome, FLU, Flu-like Symptoms, Vaccination
- Being tested
- Follow-up
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Follow-upOther
Follow-up
| Study group | Role | What they receive |
|---|---|---|
| Vaccinated | Vaccinated subjects Receives: Other: Follow-up | |
| Non-vaccinated | Non-vaccinated subjects Receives: Other: Follow-up |
What is being measured
The primary outcome is the main question the study is designed to answer.
Can the ergometric test in flu-like syndrome help in the outcome analysis of unvaccinated patients?
The investigators will analyze whether different responses to exertion, such as blood pressure disorders, are more evident in individuals with or without symptoms who have or have not been vaccinated.
Measured: 1 month
Secondary outcomes (1)
Symptoms
The investigators will document whether the symptoms are present or not.
Measured: 7 and 14 days after treadmill exercise test
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Jun 2025
- Study start1 Apr 2025
- Primary completion29 Aug 2025
- Study completion5 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Flu-like SyndromeStudies of the same condition, open and under way.
- More trials run by University of Sao PauloThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 62 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Sao Paulo
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Pedro Gabriel Senger Braga, University of Sao Paulo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07007377
- Sponsor's protocol ID
- Clínica Pró-Coração
- Status last verified
- Jun 2025
- First submitted
- 27 Mar 2025
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Data protection
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Can the Ergometric Test in Flu-like Syndrome Help in the Outcome Analysis of Unvaccinated Patients
- ClinicalTrials.gov ID
- NCT07007377
- Acronym / sponsor ID
- Clínica Pró-Coração
- Conditions
- Flu-like Syndrome, FLU, Flu-like Symptoms, Vaccination
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 62 participants (actual)
- Lead sponsor
- University of Sao PauloUniversity, hospital or other
- Study start
- 1 Apr 2025 (actual)
- Primary completion
- 29 Aug 2025 (actual)
- Study completion
- 5 Dec 2025 (actual)
- First posted
- 5 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
During the flu-like syndrome, the cardiovascular risk is increased, especially in the elderly. Understanding whether blood pressure assessment during an exercise test can aid in the understanding of patient outcomes, thereby improving prognostic ability in clinical practice, is the focus of the present study. Therefore, the aim of this study is to evaluate the hemodynamic response of adults with flu-like symptoms, both vaccinated and unvaccinated, and to conduct a 30-day follow-up for assessment. Patients who are indicated for an ergometric test and present with flu-like syndrome will be selected. We will inquire about their vaccination history and perform the ergometric test to evaluate test duration, arrhythmias, and ischemias
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Vaccinated | – | Other: Follow-upVaccinated subjects |
| Non-vaccinated | – | Other: Follow-upNon-vaccinated subjects |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Adults with flu symptoms, which were vaccinated or not.
Key inclusion criteria (1 listed)
- flu-symptoms
Key exclusion criteria (1 listed)
- recent orthopedic surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Follow-upFollow-up | Other | Non-vaccinated, Vaccinated |
Primary outcome
Can the ergometric test in flu-like syndrome help in the outcome analysis of unvaccinated patients?
Time frame: 1 month
The investigators will analyze whether different responses to exertion, such as blood pressure disorders, are more evident in individuals with or without symptoms who have or have not been vaccinated.
1 secondary outcome
Symptoms
Time frame: 7 and 14 days after treadmill exercise test
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Individual participant dataSharing planned: No. Data protection
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Flu-like Syndrome and FLU, run by University of Sao Paulo at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Can the ergometric test in flu-like syndrome help in the outcome analysis of unvaccinated patients? (time frame: 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.