Parkinson DiseaseNCT07010783
Respiratory Functions in Parkinson's Disease
An observational study of Parkinson Disease, run by Ankara University at 1 site in Turkey (Türkiye).
Trial summary
The aim is to examine respiratory functions, inspiratory muscle strength, respiratory function, physical fitness and aerobic capacity in Parkinson's disease patients. Individuals between the ages of 50-80 who have been diagnosed with Parkinson's disease by a neurologist and healthy individuals with similar demographic… Read more about this study
- Who is it for?
- Ages 50 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Parkinson Disease
- How many people
- 100 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jul 2025to 20 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Patients with Parkinson's disease who came to the neurology outpatient clinic for routine examination and who met the appropriate inclusion criteria and healthy individuals with similar demographic characteristics.
Who may be able to join
- Age 50 to 80
- Mini Mental State Examination score of 24 to 30
- Diagnosed with Parkinson's Disease by a neurologist
Who cannot join
- Sözlü iletişim kuramama
- Yürüme yardımcısı kullanıma
- Ciddi görme bozukluğu, ek nörolojik bozuklukları ve/veya konjestif kalp yetmezliği olan yaşlılar
- Egzersiz yapılması tavsiye edilmeyen yaşlı yetişkinler.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Investigation of Respiratory Functions, Inspiratory Muscle Strength, Physical Fitness and Aerobic Capacity in Patients With Parkinson's Disease
The aim is to examine respiratory functions, inspiratory muscle strength, respiratory function, physical fitness and aerobic capacity in Parkinson's disease patients. Individuals between the ages of 50-80 who have been diagnosed with Parkinson's disease by a neurologist and healthy individuals with similar demographic characteristics will be included in the study as a control group. In addition, patients will be divided into three groups as above and below 2.5 and healthy controls according to the Modified Hoehn and Yahr Scale. Demographic information of the individuals will be recorded and clinical evaluations will be made. The staging of Parkinson's patients will be done with the Modified Hoehn and Yahr Scale, and the severity of the disease will be done with the Unified Parkinson's Disease Rating Scale. The inspiratory muscle strength of the individuals will be evaluated with the PowerBreath K5, respiratory functions with the Pulmonary Function Test device, and physical fitness and aerobic capacity with the Senior Fitness Test.
- Conditions
- Parkinson Disease
- Medical subject headings
- Parkinson Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Early Stage Patients with Parkinson's Disease | According to the Modified Hoehn and Yahr Scale (MHÖ), patients with a score below 2.5 | |
| Advanced Stage Patients with Parkinson's Disease | According to the Modified Hoehn and Yahr Scale (MHÖ), patients with 2.5 and above | |
| Control Group | Healthy individuals with similar demographic characteristics |
What is being measured
The primary outcome is the main question the study is designed to answer.
Inspiratory Muscle Strength Measurement
In this study, the inspiratory muscle strength of the participants will be measured using the Power Breath device.
Measured: Baseline
Unified Parkinson's Disease Rating Scale
This scale will evaluate the severity and stage of the participants' Parkinson's disease.
Measured: Baseline
Evaluation of Respiratory Functions
Participants' respiratory functions will be evaluated using a standard respiratory function test device.
Measured: Baseline
Senior Fitness Test
The physical fitness levels of the participants will be evaluated using the Senior Fitness Test.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jun 2025
- Study start1 Jul 2025
- Primary completion1 Dec 2026 (estimated)
- Study completion20 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Parkinson DiseaseStudies of the same condition, open and under way.
- More trials run by Ankara UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ankara University
- Sponsor type
- University, hospital or other
- Collaborators
- Hacettepe University, Atılım University
- Responsible party
- Principal investigator, Büşra Seçkinoğulları Korkusuz, Ankara University
- Investigators
- Süleyman Korkusuz, PhD, Study chair, Atılım UniversityAyla Fil Balkan, Assoc Prof, Study chair, Hacettepe UniversityGül Yalçın Çakmaklı, Assoc Prof, Study chair, Hacettepe UniversityNeslihan Durutürk, Prof.Dr, Study chair, Baskent University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07010783
- Sponsor's protocol ID
- E-59394181-604.01-112206
- Status last verified
- Jun 2026
- First submitted
- 30 May 2025
- Last updated
- 29 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Shill H, Stacy M. Respiratory function in Parkinson's disease. Clin Neurosci. 1998;5(2):131-5.
PubMed 10785839Morris ME, Iansek R, Matyas TA, Summers JJ. Ability to modulate walking cadence remains intact in Parkinson's disease. J Neurol Neurosurg Psychiatry. 1994 Dec;57(12):1532-4. doi: 10.1136/jnnp.57.12.1532.
PubMed 7798986
Study at a glance
From the registry record, last updated by the sponsor on 29 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of Respiratory Functions, Inspiratory Muscle Strength, Physical Fitness and Aerobic Capacity in Patients With Parkinson's Disease
- ClinicalTrials.gov ID
- NCT07010783
- Acronym / sponsor ID
- E-59394181-604.01-112206
- Conditions
- Parkinson Disease
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Ankara UniversityUniversity, hospital or other
- Collaborators
- Hacettepe University, Atılım University
- Study start
- 1 Jul 2025 (actual)
- Primary completion
- 1 Dec 2026 (estimated)
- Study completion
- 20 Dec 2026 (estimated)
- First posted
- 8 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim is to examine respiratory functions, inspiratory muscle strength, respiratory function, physical fitness and aerobic capacity in Parkinson's disease patients. Individuals between the ages of 50-80 who have been diagnosed with Parkinson's disease by a neurologist and healthy individuals with similar demographic characteristics will be included in the study as a control group. In addition, patients will be divided into three groups as above and below 2.5 and healthy controls according to the Modified Hoehn and Yahr Scale. Demographic information of the individuals will be recorded and clinical evaluations will be made. The staging of Parkinson's patients will be done with the Modified Hoehn and Yahr Scale, and the severity of the disease will be done with the Unified Parkinson's Disease Rating Scale. The inspiratory muscle strength of the individuals will be evaluated with the PowerBreath K5, respiratory functions with the Pulmonary Function Test device, and physical fitness and aerobic capacity with the Senior Fitness Test.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Early Stage Patients with Parkinson's Disease | – | –According to the Modified Hoehn and Yahr Scale (MHÖ), patients with a score below 2.5 |
| Advanced Stage Patients with Parkinson's Disease | – | –According to the Modified Hoehn and Yahr Scale (MHÖ), patients with 2.5 and above |
| Control Group | – | –Healthy individuals with similar demographic characteristics |
Who may qualify
- Ages
- 50 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with Parkinson's disease who came to the neurology outpatient clinic for routine examination and who met the appropriate inclusion criteria and healthy individuals with similar demographic characteristics.
Key inclusion criteria (3 listed)
- Age 50 to 80
- Mini Mental State Examination score of 24 to 30
- Diagnosed with Parkinson's Disease by a neurologist
Key exclusion criteria (4 listed)
- Sözlü iletişim kuramama
- Yürüme yardımcısı kullanıma
- Ciddi görme bozukluğu, ek nörolojik bozuklukları ve/veya konjestif kalp yetmezliği olan yaşlılar
- Egzersiz yapılması tavsiye edilmeyen yaşlı yetişkinler.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Inspiratory Muscle Strength Measurement
Time frame: Baseline
In this study, the inspiratory muscle strength of the participants will be measured using the Power Breath device.
Unified Parkinson's Disease Rating Scale
Time frame: Baseline
This scale will evaluate the severity and stage of the participants' Parkinson's disease.
Evaluation of Respiratory Functions
Time frame: Baseline
Participants' respiratory functions will be evaluated using a standard respiratory function test device.
Senior Fitness Test
Time frame: Baseline
The physical fitness levels of the participants will be evaluated using the Senior Fitness Test.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Oct 2026.
- Results publication: PubMed 10785839Shill H, Stacy M. Respiratory function in Parkinson's disease. Clin Neurosci. 1998;5(2):131-5.
- Results publication: PubMed 7798986Morris ME, Iansek R, Matyas TA, Summers JJ. Ability to modulate walking cadence remains intact in Parkinson's disease. J Neurol Neurosurg Psychiatry. 1994 Dec;57(12):1532-4. doi: 10.1136/jnnp.57.12.1532.
- Individual participant dataSharing planned: No
Related trials for Parkinson Disease
Not yet recruiting
Comparative Effects of Virtual Reality and Proprioceptive Neuromuscular Facilitation in Patients With Parkinson's Disease
Parkinson Disease
Active, not recruiting
Myrosinase Bioactivated Gglucoraphanin for the Treatment of Neurodegenerative Diseases (GRA-MYR-ND)
PARKINSON DISEASE (Disorder), Multiple Sclerosis (MS) - Relapsing-remitting
RecruitingPhase 1
Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients
Parkinson Disease, Parkinson's Disease
Not yet recruitingObservational study
Longitudinal Observation of Neurodegeneration in Parkinson's Disease Using Molecular Imaging and Blood Biomarkers
Idiopathic Parkinson Disease
Active, not recruitingPhase 2
A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer
Metastatic Colorectal Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Süleyman Korkusuz, PhD study chair
Atılım University
Ayla Fil Balkan, Assoc Prof study chair
Hacettepe University
Gül Yalçın Çakmaklı, Assoc Prof study chair
Hacettepe University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Parkinson Disease, run by Ankara University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 29 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Inspiratory Muscle Strength Measurement (time frame: Baseline). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07010783, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Oct 2026.