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AnxietyNCT07020975

Virtual Reality for Anxiety Relief in Infertile Women

A study testing VR Glasses in people with Anxiety and Assisted Reproductive Treatments, run by Cyprus Aydin University at 1 site in Cyprus.

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Sites and contacts
Official record
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Trial summary

This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures. The clinical trial will involve 80 participants, aged 18 to 50, who are receiving treatment at a healthcare facility in the Turkish Republic of Northern Cyprus (TRNC). Read more about this study

Who is it for?
Ages 18 to 50 years, women onlyHealthy volunteers can take part
Conditions the study is for
Anxiety, Assisted Reproductive Treatments, Women
What is being tested?
VR Glasses
Type of treatment
Medical device
Could I receive a placebo?
No, everyone receives an active treatment
How many people
80 participants
Where
1 siteCyprus
Study dates
1 Mar 2025to 1 Mar 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 50 years
  • Women only
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Volunteered to participate in the research,
  • 18-50 years old
  • No vision and hearing problems,
  • Not disoriented in time and place,
  • Primary infertile
  • Not having communication problem
  • Can read \& write
  • No mental pathological disease

Who cannot join

  • Secondary infertility
  • Having experienced bleeding, miscarriage, etc. after embryo transfer,
  • Difficulty communicating,
  • Problems such as migraine, vertigo, dizziness,
  • Patients who wear prescription glasses and have vision problems without glasses
  • Refused to participate in the research
  • Patients with psychiatric pathology

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Cyprus1 site

  • Cyprus Aydin University

    Girne Kepuveia, Keryneia, 99000

Other trials in Cyprus

About this study

Official title: The Effect of Virtual Reality Application on Anxiety Before and After Embryo Transfer in Infertile Women

This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures. The clinical trial will involve 80 participants, aged 18 to 50, who are receiving treatment at a healthcare facility in the Turkish Republic of Northern Cyprus (TRNC). The primary objective is to evaluate the effectiveness of VR as an intervention for reducing anxiety in individuals undergoing assisted reproductive treatments.

Read the detailed description

This doctoral study aims to evaluate the use of virtual reality (VR) as an innovative, non-invasive intervention for managing anxiety during embryo transfer in assisted reproductive technology (ART). A randomized clinical trial will be conducted with 80 participants, aged 18 to 50, undergoing fertility treatment at a healthcare facility in the Turkish Republic of Northern Cyprus (TRNC).

Participants will be randomly assigned to one of two groups: the intervention group (n=40), which will experience a VR session both before and after the embryo transfer, and the control group (n=40), which will receive standard care without VR. Anxiety levels will be assessed using the State-Trait Anxiety Inventory (STAI) at two time points-pre- and post-embryo transfer.

The primary objective of this study is to determine the effectiveness of VR in reducing procedural anxiety, a factor known to negatively affect patient experience and potentially influence treatment outcomes. The findings are expected to support the integration of patient-centered, technology-enhanced strategies in reproductive healthcare practices.

Being tested
VR Glasses
Keywords
Anxiety, Assisted Reproductive Treatments, Women, Nurse, VR, Technology, Infertility, Embryo Transfer
Medical subject headings
Anxiety Disorders, Infertility

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • VR GlassesDevice

    VR Glasses is used to help people be in a virtual reality other than their real life. What we use this for; to get away infertile women from her stressfull environment to another virtual reality before their embryo transfer.

Study groups in NCT07020975
Study groupRoleWhat they receive
Intervention Group with VR GlassesExperimentalForty women will experience a calming ZEN music soundtrack and view natural landscapes through VR glasses both before and after the embryo transfer procedure.
Receives: Device: VR Glasses
Control Group with routine careNo interventionForty women will receive standard routine care before and after the embryo transfer procedure (Explanation of how to use the medication).

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Anxiety level of the women who went through embryo transfer.

    This study aims to assess the anxiety levels of women who undergo a virtual reality (VR) experience before and after embryo transfer. The participants will be divided into two groups: those who receive relaxing Zen music and view natural landscapes through VR glasses, and those who do not. Anxiety levels will be objectively measured using the State-Trait Anxiety Inventory, both before and after the embryo transfer procedure.

    Measured: 1 year

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted13 Jun 2025
  2. Study start1 Mar 2025
  3. Primary completion1 Mar 2026 (estimated)
  4. Study completion1 Mar 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Participant
Enrolment
80 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07020975
Sponsor's protocol ID
2025/04.007
Status last verified
Jun 2025
First submitted
3 Jun 2025
Last updated
13 Jun 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Garcia-Palacios A, Hoffman H, Carlin A, Furness TA 3rd, Botella C. Virtual reality in the treatment of spider phobia: a controlled study. Behav Res Ther. 2002 Sep;40(9):983-93. doi: 10.1016/s0005-7967(01)00068-7.

    PubMed 12296495

  • Freeman D, Reeve S, Robinson A, Ehlers A, Clark D, Spanlang B, Slater M. Virtual reality in the assessment, understanding, and treatment of mental health disorders. Psychol Med. 2017 Oct;47(14):2393-2400. doi: 10.1017/S003329171700040X. Epub 2017 Mar 22.

    PubMed 28325167

Questions about this trial

What is this clinical trial studying?

A study testing VR Glasses in people with Anxiety and Assisted Reproductive Treatments, run by Cyprus Aydin University at 1 site in Cyprus.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 8 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: enrolling by invitation, as of the sponsor's last update on 13 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Cyprus. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Anxiety level of the women who went through embryo transfer. (time frame: 1 year). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07020975, which also lists 2 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Jun 2025; AzTrials last refreshed its copy on 26 Oct 2026.

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