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Chronic Respiratory DiseasesCPHMSNCT07026370

Chinese Population Health and Multimorbidity Study

An observational study of Chronic Respiratory Diseases and Cardiovascular and Cerebrovascular Diseases, run by China-Japan Friendship Hospital at 1 site in China.

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Sites and contacts
Official record
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Trial summary

The Chinese Population Health and Multimorbidity Study (CPHMS; initially named China Pulmonary Health Study, CPHS) was a large-scale epidemiological survey designed to investigate the pulmonary health of Chinese adults aged 20 years or older leveraging a multistage stratified sampling scheme between 2011 and 2014 in… Read more about this study

Who is it for?
Ages 20 years and olderHealthy volunteers can take part
How many people
50,991 participants
Where
1 siteChina
Study dates
1 Jan 2011to 30 Jun 2027
Phase
Observational
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 years and older
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Study population: A total number of 50,991 adults aged 20 years or older from 10 representative provinces and municipalities of China participated in the CPHMS baseline survey between 2011 and 2014. In the follow-up investigation, ideally all the baseline participants should be contacted.

Who may be able to join

  • (1) the individuals who participated in the CPHMS baseline survey;
  • (2) their ID number and phone number are available;
  • (3) sign the informed consent.

Who cannot join

  • (1) incapable of taking pre- and post-bronchodilator spirometry tests;
  • (2) request to withdraw the informed consent;
  • (3) terminate due to medical or ethical considerations judged by the investigators and/or ethics committee.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

China1 site

  • China-Japan Friendship Hospital

    Beijing, Beijing Municipality, 100029

Other trials in China

About this study

Official title: The Chinese Population Health and Multimorbidity Study: Baseline Survey, and Follow-up Investigation

The Chinese Population Health and Multimorbidity Study (CPHMS; initially named China Pulmonary Health Study, CPHS) was a large-scale epidemiological survey designed to investigate the pulmonary health of Chinese adults aged 20 years or older leveraging a multistage stratified sampling scheme between 2011 and 2014 in mainland China. Briefly, a total number of 57,779 local residents were recruited from 10 representative provinces and municipalities and were invited to participate in the study. A final number of 50,991 adults who met the major inclusion criteria could be considered in further analyses.

In order to investigate the changes of pulmonary health and disease status (e.g. occurrence and development of chronic respiratory diseases and other important relevant multimorbidities, lung function indices, etc.) and corresponding impact factors in the CPHMS study population, we plan to initiate the first round of follow-up investigation between 2025 and 2027 (planned) , i.e. more than 10 years after the baseline survey.

Keywords
Multimorbidities, Epidemiological survey, Cohort, Population medicine
Medical subject headings
Cerebrovascular Disorders, Neoplasms, Metabolic Diseases

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Occurrence of multimorbidities

    Occurrence of chronic respiratory diseases, cardiovascular and cerebrovascular diseases, malignant tumors, and/or metabolic diseases, etc.

    Measured: Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS)

Secondary outcomes (4)

  1. Changes of lung function, forced expiratory volume in one second (FEV1)

    Changes of pre- and post-bronchodilator spirometry test indices, FEV1

    Measured: Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS)

  2. Changes of lung function, forced vital capacity (FVC)

    Changes of pre- and post-bronchodilator spirometry test indices, FVC

    Measured: Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS)

  3. Changes of lung function, FEV1/FVC

    Changes of pre- and post-bronchodilator spirometry test indices, FEV1/FVC

    Measured: Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS)

  4. Changes of lung function, the percentage of measured FEV1 value to the predicted value (FEV1%pred)

    Changes of pre- and post-bronchodilator spirometry test indices, FEV1%pred

    Measured: Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Jun 2025
  2. Study start1 Jan 2011
  3. Primary completion30 Jun 2027 (estimated)
  4. Study completion30 Jun 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
50,991 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07026370
Sponsor's protocol ID
2022-ZHCH330-01
Other IDs
2022-ZHCH330-01, 2023FY100600, 2016YFC1303900, 201002008
Acronym
CPHMS
Status last verified
Mar 2026
First submitted
30 May 2025
Last updated
5 Mar 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Wang C, Xu J, Yang L, Xu Y, Zhang X, Bai C, Kang J, Ran P, Shen H, Wen F, Huang K, Yao W, Sun T, Shan G, Yang T, Lin Y, Wu S, Zhu J, Wang R, Shi Z, Zhao J, Ye X, Song Y, Wang Q, Zhou Y, Ding L, Yang T, Chen Y, Guo Y, Xiao F, Lu Y, Peng X, Zhang B, Xiao D, Chen CS, Wang Z, Zhang H, Bu X, Zhang X, An L, Zhang S, Cao Z, Zhan Q, Yang Y, Cao B, Dai H, Liang L, He J; China Pulmonary Health Study Group. Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study. Lancet. 2018 Apr 28;391(10131):1706-1717. doi: 10.1016/S0140-6736(18)30841-9. Epub 2018 Apr 9.

    PubMed 29650248

  • Huang K, Yang T, Xu J, Yang L, Zhao J, Zhang X, Bai C, Kang J, Ran P, Shen H, Wen F, Chen Y, Sun T, Shan G, Lin Y, Xu G, Wu S, Wang C, Wang R, Shi Z, Xu Y, Ye X, Song Y, Wang Q, Zhou Y, Li W, Ding L, Wan C, Yao W, Guo Y, Xiao F, Lu Y, Peng X, Zhang B, Xiao D, Wang Z, Chen Z, Bu X, Zhang H, Zhang X, An L, Zhang S, Zhu J, Cao Z, Zhan Q, Yang Y, Liang L, Tong X, Dai H, Cao B, Wu T, Chung KF, He J, Wang C; China Pulmonary Health (CPH) Study Group. Prevalence, risk factors, and management of asthma in China: a national cross-sectional study. Lancet. 2019 Aug 3;394(10196):407-418. doi: 10.1016/S0140-6736(19)31147-X. Epub 2019 Jun 20.

    PubMed 31230828

  • Xiao D, Chen Z, Wu S, Huang K, Xu J, Yang L, Xu Y, Zhang X, Bai C, Kang J, Ran P, Shen H, Wen F, Yao W, Sun T, Shan G, Yang T, Lin Y, Zhu J, Wang R, Shi Z, Zhao J, Ye X, Song Y, Wang Q, Hou G, Zhou Y, Li W, Ding L, Wang H, Chen Y, Guo Y, Xiao F, Lu Y, Peng X, Zhang B, Wang Z, Zhang H, Bu X, Zhang X, An L, Zhang S, Cao Z, Zhan Q, Yang Y, Liang L, Liu Z, Zhang X, Cheng A, Cao B, Dai H, Chung KF, He J, Wang C; China Pulmonary Health Study Group. Prevalence and risk factors of small airway dysfunction, and association with smoking, in China: findings from a national cross-sectional study. Lancet Respir Med. 2020 Nov;8(11):1081-1093. doi: 10.1016/S2213-2600(20)30155-7. Epub 2020 Jun 26.

    PubMed 32598906

Questions about this trial

What is this clinical trial studying?

An observational study of Chronic Respiratory Diseases and Cardiovascular and Cerebrovascular Diseases, run by China-Japan Friendship Hospital at 1 site in China.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: enrolling by invitation, as of the sponsor's last update on 5 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Occurrence of multimorbidities (time frame: Since the year of baseline survey till the year of 2025 and 2027 (the first round of follow-up investigation of CPHMS)). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07026370, which also lists 3 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2026.

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