Clinical trials: Endocrine and Metabolic Diseases
Type 2 Diabetes
Diamel in the Treatment of Type 2 Diabetic Patients Receiving Insulin Therapy
The purpose of this study is to assess the efficacy of Diamel (dietary supplement) administration in the treatment of patients with type 2 diabetes receiving insulin therapy.
- Trial name
- NCT00994266
- Testing
- Diamel
- Where
- Cuba
- Volunteers
- 116 people
- Sponsor
- Catalysis SL
Diet, Healthy, Blood Sugar; High
Barley Beta-glucan, Glycemic Control, and Appetite
Novel barley varieties high in the soluble fiber β-glucan have the capacity to improve population health through improving glycemic control.
- Conditions
- Diet, Healthy, Blood Sugar; High, Diabetes, Appetite and General Nutritional Disorders
- Trial name
- NCT06146322
- Testing
- WR, LB, MB
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Washington State University
Diabetes Mellitus, Type 2
Placebo Controlled Metformin and Sulfonylurea Combination Study in Patients With Type 2 Diabetes (0767-025)
The purpose of this study is to compare how MK0767 and metformin and sulfonylurea therapy lower blood glucose in patients with inadequate glycemic control This is an early phase trial and some specific protocol information is in…
- Trial name
- NCT00543751
- Testing
- MK0767
- Volunteers
- 610 people
- Sponsor
- Merck Sharp & Dohme LLC
Prediabetic State, Hyperglycemia
Effect of Zinc on Glucose Homeostasis
The purpose of this investigation is to evaluate the impact of zinc supplementation on fasting glucose levels, hemoglobin A1c (HbA1c), and other indices of glucose homeostasis in individuals with prediabetes.
- Trial name
- NCT05835037
- Testing
- Zinc Gluconate 30 MG
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Maryland, Baltimore
Type 2 Diabetes Mellitus, Coronary Artery Disease
DARE: Diabetes in cArdiac REhabilitation
The aim of the DARE study is to see whether strict glycemic control during cardiac rehabilitation may ameliorate the improvement of exercise capacities (VO2 peak, peak workload, ventilatory threshold)in patients with type 2…
- Trial name
- NCT00354237
- Testing
- Conventional antidiabetic treatment, Intensive insulin treatment
- Where
- 12 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Obesity, Morbid
Impact of Size of Gastric Sleeve on the Weight Loss. Correlation With Gastric Function and Endocrine-metabolic Changes.
Morbid Obesity (MO) is considered the most important epidemic in the developed world in the twenty-first century. After initial assessment of morbidly obese patients and the exclusion of potentially correctable causes, management…
- Trial name
- NCT02144545
- Testing
- Bougie Size 33 Fr, Bougie Size 42 Fr, Distance pylorus 2 cm
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Type 1 Diabetes, Children
Think-Find-Solve Activities for Insulin Self-Management in Type 1 Diabetes
Children with type 1 diabetes require lifelong insulin therapy. However, improper management of insulin therapy may lead to serious, potentially life-threatening complications.
- Conditions
- Type 1 Diabetes, Children, Activity, Insulin
- Trial name
- NCT07670572
- Testing
- Insulin Self-Management Know-Find-Solve Activity Book, Routine education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Type 1 Diabetes Mellitus
Insulin Sensitivity, Impaired Counterregulation, and Glucose Variability
This protocol will investigate physiological parameters including insulin sensitivity and counterregulatory function using a mixed meal test and induced hypoglycemia in subjects with type I diabetes.
- Trial name
- BPK005 (NCT01439672)
- Testing
- Mixed meal and insulin challenge
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Virginia
Diabetes Mellitus, Congestive Heart Failure
Homing in on Health: Study of a Home Delivered Chronic Disease Self Management Program
The purpose of the study is to determine the effectiveness of a home-delivered variant of the chronic disease self management program in improving health outcomes in patients with chronic conditions.
- Conditions
- Diabetes Mellitus, Congestive Heart Failure, Arthritis, COPD
- Trial name
- NCT00263939
- Testing
- Homing in on Health
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Type 2 Diabetes
Cognitive Behavioral Intervention in Diabetes Self-Management
The proposed study is a two arm randomized controlled trial with longitudinal follow-up that compares cognitive behavioral interventions (ENHANCE) to a control group with attention.
- Trial name
- NCT01182701
- Testing
- Cognitive behavioral training
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- University of Hawaii
Third Degree Burns, Diabetes
Study of ST266 in Diabetic Subjects With Deep Burns Managed With Skin Grafts
This study is a randomized, double blind, placebo controlled trial at a single site. The primary objective is to evaluate the safety of ST266 in diabetic subjects with deep burns.
- Trial name
- NCT01715012
- Testing
- ST266, Saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Diabetic Retinopathy
Lucentis (Ranibizumab) in Diabetic Macular Oedema: a Treatment Evaluation
This exploratory study will compare the effects of ranibizumab treatment with conventional macular laser therapy for patients with diabetic macular oedema.
- Trial name
- LUCIDATE (NCT01223612)
- Testing
- Ranibizumab, Modified ETDRS laser
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Type 2 Diabetes Mellitus, Diabetic Kidney Disease
Low Carbohydrate Diet in Diabetic Kidney Disease
The current population of type 2 diabetes mellitus (T2DM) worldwide is over 200 million and Malaysia contributes to 1.2% of that number.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Obesity
- Trial name
- NCT04931030
- Testing
- Dietary advice
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Teknologi Mara
Diabetes Mellitus Type 1
Measuring and Monitoring Blood Glucose Levels Utilizing Non-invasive Blood Glucose Monitoring Device
Adequate glycemic control in patients with Diabetes Mellitus (DM) is a desired therapeutic goal that can be achieved with a true non-invasive device offering the likelihood of continuous glucose monitoring.
- Trial name
- NCT01508065
- Testing
- Glucometer CGM-305
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- GlucoVista
Foot Ulcer, Diabetes
Safety and Efficacy Study of an Interactive Wound Dressing (KC002) for the Treatment of Diabetic Foot Ulcers
The objective of this study is to determine the safety and effectiveness of a device (the KC-002 interactive wound dressing) in the promotion of healing in diabetic foot ulcers as compared with a conventional wound therapy…
- Trial name
- KC-002PT (NCT00330265)
- Testing
- KC-002, Conventional Wound Therapy
- Where
- 21 sites in United States
- Volunteers
- 300 people
- Sponsor
- KeraCure
SIAD - Syndrome of Inappropriate Antidiuresis, Hyponatremia
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
Hyponatremia is a common electrolyte imbalance which often results from hormonal disregulation. The study aims to investigate whether the apelin hormone, which plays a role in regulating salt and water balance in the body, can be…
- Trial name
- ESCAPE (NCT06277336)
- Testing
- Apelin Low Dose, Apelin High Dose, Selected Apelin Dose
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Type 2 Diabetes, ObesityType 2 Diabetes Mellitus
The Impact of Laser Acupuncture on Type 2 Diabetes
Laser Acupuncture for Type 2 Diabetes and Body Shape The goal of this clinical trial is to learn if laser acupuncture can help improve body shape and overall health in women with Type 2 Diabetes (T2D).
- Trial name
- LA/ABSI (NCT07661160)
- Testing
- Laser Acupuncture
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Diabetes
A Study to Evaluate Glucose and Insulin Response to Nutralin
The purpose of this study is to evaluate how an investigational food product affects a healthy person's blood sugar and insulin levels.
- Trial name
- NCT01275820
- Testing
- Nutralin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Avera McKennan Hospital & University Health Center
Diabetes, Steatosis of Liver
Biomarkers of Steatohepatitis in Type 2 Diabetes Patients
The aims of the study are to identify a subgroup of type 2 diabetics at risk of developing and progressing to non-alcoholic steatohepatitis (NASH), to correlate clinical and laboratory parameters with sonographic and…
- Trial name
- STEDIB (NCT07098520)
- Testing
- No intervention, just observation
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Diabetes, Diabetes Mellitus, Type 2
The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to investigate the efficacy and safety of liraglutide compared to sitagliptin, both as add-on to metformin in Chinese subjects with type 2 diabetes inadequately controlled…
- Trial name
- NCT02008682
- Testing
- liraglutide, sitagliptin
- Where
- 25 sites in China
- Volunteers
- 368 people
- Sponsor
- Novo Nordisk A/S
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