Y-balanceNCT07068984
Assessing Lower Extremity Dynamic Stability in Middle-Aged and Elderly Patients With Patellofemoral Pain Using the Y-Balance Test
An observational study of Y-balance and Patellofemoral Pain Syndrome, run by Peking University Third Hospital at 1 site in China.
Trial summary
Background: Patellofemoral pain syndrome (PFPS) is a common functional disorder of knee joint. Its etiology involves biomechanical abnormalities and dynamic stability defects. Most of the existing studies focus on young people, and the biomechanical characteristics and functional compensation mechanism of middle-aged… Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Y-balance, Patellofemoral Pain Syndrome
- What is being tested?
- Differences between lower limb balances were assessed by the Y-Balance test
- How many people
- 70 participants
- Where
- 1 siteChina
- Study dates
- 1 Mar 2025to 10 Apr 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Study population: People with patellar pain
Who may be able to join
- Aged between 40 and 60 years
- Clinically diagnosed with patellofemoral pain (PFP) with symptoms lasting ≥3 months
- No other serious lower extremity disorders
- No neurological diseases
- No history of recent lower extremity surgery (<12 months)
- No history of major lower extremity trauma
- Control group: Age- and sex-matched healthy volunteers without knee pain or lower limb dysfunction
Who cannot join
- Acute inflammatory conditions Meniscus injury Knee ligament injury Intra-articular fracture Bone tumor Bone tuberculosis
- Neurovascular injury including:
- Stroke history
- Parkinson's disease Subjective unwillingness to comply with testing Inability to complete Y-Balance Test
- Serious systemic diseases affecting:
- Cardiovascular system Hepatic function Renal function Hematological system
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Assessing Lower Extremity Dynamic Stability in Middle-Aged and Elderly Patients With Patellofemoral Pain Using the Y-Balance Test: A Cross-Sectional Study
Background: Patellofemoral pain syndrome (PFPS) is a common functional disorder of knee joint. Its etiology involves biomechanical abnormalities and dynamic stability defects. Most of the existing studies focus on young people, and the biomechanical characteristics and functional compensation mechanism of middle-aged and elderly patients are still unclear. The Y-Balance test is becoming an important tool in PFPS research because of its sensitivity to assess the dynamic balance ability of lower limbs. Objective: To analyze the functional characteristics of lower limbs of PFPS patients aged 40-60 by Y-Balance test, and to explore the differences between PFPS patients and healthy people, so as to provide evidence for clinical rehabilitation. Methods: A cross-sectional observational study was conducted in 49 PFPS patients and 21 healthy controls. Y-Balance test was used to evaluate bilateral forward difference, composite score, lateral and posterior balance, symmetry ratio and bilateral difference. SPSS 25.0 was used for statistical analysis.
- Conditions
- Y-balance, Patellofemoral Pain Syndrome
- Being tested
- Differences between lower limb balances were assessed by the Y-Balance test
- Medical subject headings
- Patellofemoral Pain Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Differences between lower limb balances were assessed by the Y-Balance testOther
The Y-Balance test was used to evaluate bilateral anterior difference, composite score, lateral and posterior balance, symmetry ratio and bilateral difference
| Study group | Role | What they receive |
|---|---|---|
| Twenty-one healthy controls were enrolled | 2 Receives: Other: Differences between lower limb balances were assessed by the Y-Balance test | |
| A total of 49 patients with PFPS and 21 healthy controls were enrolled | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Analysis of Y-balance characteristics of patellofemoral pain syndrome
Outcome Measure Title:Y-Balance Test (YBT) Reach Distance (cm) - Comparison between Patellofemoral Pain Syndrome (PFPS) Patients (Aged 40-60 Years) and Healthy Controls Outcome Measure Description:The Y-Balance Test (YBT) was used to assess dynamic balance function of the lower limbs in participants.
Metrics Measured: The maximum reach distance (in centimeters, cm) achieved by participants in three directions (Anterior, Posteromedial, Posterolateral) during single-leg stance.
Data Summary:The average maximum reach distance (cm) from three valid trials was calculated for each direction, separately for the left and right legs.
Comparative Analysis: The average maximum reach distance (cm) in each direction for the left and right legs in the PFPS patient group (aged 40-60 years) were compared with the corresponding metrics in an age- and sex-matched group of healthy controls to analyze between-group differences.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jul 2025
- Study start1 Mar 2025
- Primary completion1 Apr 2025
- Study completion10 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Y-balanceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Peking University Third Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07068984
- Sponsor's protocol ID
- M2022744
- Status last verified
- Apr 2025
- First submitted
- 28 May 2025
- Last updated
- 16 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
Zheng Z, Fan H, Hongjie H, Jianquan W. Deficits in dynamic stability revealed by the Y-Balance test in middle-aged and elderly adults with patellofemoral pain. J Orthop Surg Res. 2026 Jan 28;21(1):147. doi: 10.1186/s13018-026-06684-9.
PubMed 41593626
Study at a glance
From the registry record, last updated by the sponsor on 16 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessing Lower Extremity Dynamic Stability in Middle-Aged and Elderly Patients With Patellofemoral Pain Using the Y-Balance Test: A Cross-Sectional Study
- ClinicalTrials.gov ID
- NCT07068984
- Acronym / sponsor ID
- M2022744
- Conditions
- Y-balance, Patellofemoral Pain Syndrome
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Peking University Third HospitalUniversity, hospital or other
- Study start
- 1 Mar 2025 (actual)
- Primary completion
- 1 Apr 2025 (actual)
- Study completion
- 10 Apr 2025 (actual)
- First posted
- 16 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background: Patellofemoral pain syndrome (PFPS) is a common functional disorder of knee joint. Its etiology involves biomechanical abnormalities and dynamic stability defects. Most of the existing studies focus on young people, and the biomechanical characteristics and functional compensation mechanism of middle-aged and elderly patients are still unclear. The Y-Balance test is becoming an important tool in PFPS research because of its sensitivity to assess the dynamic balance ability of lower limbs. Objective: To analyze the functional characteristics of lower limbs of PFPS patients aged 40-60 by Y-Balance test, and to explore the differences between PFPS patients and healthy people, so as to provide evidence for clinical rehabilitation. Methods: A cross-sectional observational study was conducted in 49 PFPS patients and 21 healthy controls. Y-Balance test was used to evaluate bilateral forward difference, composite score, lateral and posterior balance, symmetry ratio and bilateral difference. SPSS 25.0 was used for statistical analysis.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Twenty-one healthy controls were enrolled | – | Other: Differences between lower limb balances were assessed by the Y-Balance test2 |
| A total of 49 patients with PFPS and 21 healthy controls were enrolled | – | – |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- People with patellar pain
Key inclusion criteria (7 listed)
- Aged between 40 and 60 years
- Clinically diagnosed with patellofemoral pain (PFP) with symptoms lasting ≥3 months
- No other serious lower extremity disorders
- No neurological diseases
- No history of recent lower extremity surgery (<12 months)
Key exclusion criteria (6 listed)
- Acute inflammatory conditions Meniscus injury Knee ligament injury Intra-articular fracture Bone tumor Bone tuberculosis
- Stroke history
- Parkinson's disease Subjective unwillingness to comply with testing Inability to complete Y-Balance Test
- Cardiovascular system Hepatic function Renal function Hematological system
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Differences between lower limb balances were assessed by the Y-Balance testThe Y-Balance test was used to evaluate bilateral anterior difference, composite score, lateral and posterior balance, symmetry ratio and bilateral difference | Other | Twenty-one healthy controls were enrolled |
Primary outcome
Analysis of Y-balance characteristics of patellofemoral pain syndrome
Time frame: Baseline
Outcome Measure Title:Y-Balance Test (YBT) Reach Distance (cm) - Comparison between Patellofemoral Pain Syndrome (PFPS) Patients (Aged 40-60 Years) and Healthy Controls Outcome Measure Description:The Y-Balance Test (YBT) was used to assess dynamic balance function of the lower limbs in participants. Metrics Measured: The maximum reach distance (in centimeters, cm) achieved by participants in three directions (Anterior, Posteromedial, Posterolateral) during single-leg stance. Data Summary:The average maximum reach distance (cm) from three valid trials was calculated for each direction, separately for the left and right legs. Comparative Analysis: The average maximum reach distance (cm) in each direction for the left and right legs in the PFPS patient group (aged 40-60 years) were compared with the corresponding metrics in an age- and sex-matched group of healthy controls to analyze between-group differences.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2025.
- Derived from this study: PubMed 41593626Zheng Z, Fan H, Hongjie H, Jianquan W. Deficits in dynamic stability revealed by the Y-Balance test in middle-aged and elderly adults with patellofemoral pain. J Orthop Surg Res. 2026 Jan 28;21(1):147. doi: 10.1186/s13018-026-06684-9.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Y-balance and Patellofemoral Pain Syndrome, run by Peking University Third Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Analysis of Y-balance characteristics of patellofemoral pain syndrome (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07068984, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2025.