Alveolar Bone LossMISTTNCT07079917
Alveolar Ridge Augmentation Using Minimally Invasive Subperiosteal Tunneling With Xenogenic Bone Graft and PRF
A study testing subperiosteal tunneling for horizontal alveolar ridge augmentation and conventional alveolar ridge augmentation in people with Alveolar Bone Loss, run by Fayoum University at 1 site in Egypt.
Trial summary
surgical horizontal augmentation for maxillary alveolar ridge using minimally invasive subperiosteal tunneling in comparison to conventional surgical technique Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Alveolar Bone Loss
- What is being tested?
- subperiosteal tunneling for horizontal alveolar ridge augmentation and conventional alveolar ridge augmentation
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 16 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Aug 2025to 21 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adults over 18 years old seeking an implant-supported restoration with deficient horizontal posterior maxillary alveolar ridge, at area of one or two missed teeth of less than 5 mm buccolingual width.
- Minimum vertical height of 8 mm.
- Gingival tissue of healthy adequate keratinization, more than 2mm.
Who cannot join
- The presence of uncontrolled diabetes or any other systemic condition which may complicate the surgical procedure or interfere with bone healing
- Radiotherapy to the head and neck region
- Chemotherapy within the last 12 months
- Uncontrolled periodontitis
- Smoking
- Bisphosphonate therapy
- Pregnancy
- Presence of periapical infection or lesion
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Alveolar Ridge Augmentation Using Minimally Invasive Subperiosteal Tunneling With Xenogenic Bone Graft and Platelet-Rich Fibrin: Randomized Controlled Trial
surgical horizontal augmentation for maxillary alveolar ridge using minimally invasive subperiosteal tunneling in comparison to conventional surgical technique
- Conditions
- Alveolar Bone Loss
- Being tested
- subperiosteal tunneling for horizontal alveolar ridge augmentation, conventional alveolar ridge augmentation
- Medical subject headings
- Alveolar Bone Loss
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
subperiosteal tunneling for horizontal alveolar ridge augmentationProcedure or surgery
subperiosteal dissection through horizontal incision only
conventional alveolar ridge augmentationProcedure or surgery
horizontal alveolar ridge augmentation through trapezoidal flap
| Study group | Role | What they receive |
|---|---|---|
| subperiosteal tunneling for horizontal alveolar ridge augmentation | Active comparator | subperiosteal dissection through horizontal incision Receives: Procedure: subperiosteal tunneling for horizontal alveolar ridge augmentation |
| conventional surgical approach for horizontal alveolar ridge augmentation | Active comparator | conventional full thickness trapezoidal flap for alveolar ridge augmentation Receives: Procedure: conventional alveolar ridge augmentation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Maxillary alveolar bone width
increase of the alveolar bone buccolingually for horizontal ridge augmentation
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jul 2025
- Study start1 Aug 2025 (estimated)
- Primary completion21 Aug 2025 (estimated)
- Study completion21 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alveolar Bone LossStudies of the same condition, open and under way.
- More trials run by Fayoum UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 16 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Fayoum University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Abanoub Maged Sobhy Morkos, Fayoum University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07079917
- Sponsor's protocol ID
- will be ready at end of study
- Acronym
- MISTT
- Status last verified
- Jul 2025
- First submitted
- 2 Jul 2025
- Last updated
- 23 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Alveolar Ridge Augmentation Using Minimally Invasive Subperiosteal Tunneling With Xenogenic Bone Graft and Platelet-Rich Fibrin: Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07079917
- Acronym / sponsor ID
- MISTT / will be ready at end of study
- Conditions
- Alveolar Bone Loss
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 16 participants (estimated)
- Lead sponsor
- Fayoum UniversityUniversity, hospital or other
- Study start
- 1 Aug 2025 (estimated)
- Primary completion
- 21 Aug 2025 (estimated)
- Study completion
- 21 Jun 2026 (estimated)
- First posted
- 23 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
surgical horizontal augmentation for maxillary alveolar ridge using minimally invasive subperiosteal tunneling in comparison to conventional surgical technique
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| subperiosteal tunneling for horizontal alveolar ridge augmentation | Active comparator | Procedure: subperiosteal tunneling for horizontal alveolar ridge augmentationsubperiosteal dissection through horizontal incision |
| conventional surgical approach for horizontal alveolar ridge augmentation | Active comparator | Procedure: conventional alveolar ridge augmentationconventional full thickness trapezoidal flap for alveolar ridge augmentation |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Adults over 18 years old seeking an implant-supported restoration with deficient horizontal posterior maxillary alveolar ridge, at area of one or two missed teeth of less than 5 mm buccolingual width.
- Minimum vertical height of 8 mm.
- Gingival tissue of healthy adequate keratinization, more than 2mm.
Key exclusion criteria (8 listed)
- The presence of uncontrolled diabetes or any other systemic condition which may complicate the surgical procedure or interfere with bone healing
- Radiotherapy to the head and neck region
- Chemotherapy within the last 12 months
- Uncontrolled periodontitis
- Smoking
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| subperiosteal tunneling for horizontal alveolar ridge augmentationsubperiosteal dissection through horizontal incision only | Procedure or surgery | subperiosteal tunneling for horizontal alveolar ridge augmentation |
| conventional alveolar ridge augmentationhorizontal alveolar ridge augmentation through trapezoidal flap | Procedure or surgery | conventional surgical approach for horizontal alveolar ridge augmentation |
Primary outcome
Maxillary alveolar bone width
Time frame: 6 months
increase of the alveolar bone buccolingually for horizontal ridge augmentation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing subperiosteal tunneling for horizontal alveolar ridge augmentation and conventional alveolar ridge augmentation in people with Alveolar Bone Loss, run by Fayoum University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 23 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Maxillary alveolar bone width (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jul 2025.