Cervicogenic HeadacheCGHNCT07086898
Impact of Adding Integrated Neuromuscular Inhibition Technique to Postural Correction Exercises in Patients With Cervicogenic Headache
A study testing Integrated Neuromuscular Inhibition Technique and Postural Correction Exercise in people with Cervicogenic Headache, run by Cairo University.
Trial summary
this study will be conducted to investigate the impact of adding integrated neuromuscular inhibition technique to postural correction exercises in patients with cervicogenic headache Read more about this study
- Who is it for?
- Ages 20 to 60 years
- Conditions the study is for
- Cervicogenic Headache
- What is being tested?
- Integrated Neuromuscular Inhibition Technique and Postural Correction Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- No sites listed yet
- Study dates
- 30 Jul 2025to 25 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- 20 to 60 years old patient with unilaterally of the head pain
- pain triggered by external pressure over the upper cervical joints (c1-c3)
- pain elicited by the neck movements, and/or sustained awkward positions with reduced neck ROM
- headache intensity pain score of at least 20mm on the Visual analogue scale (VAS)
- headache frequency of at least once a week for at least 3 months
- minimum neck disability index score of 10 points or greater
Who cannot join
- Migraine, tension- type headache, tumor, osteoporosis, fracture, rheumatoid arthritis and metabolic diseases.
- Prolonged history of steroid use.
- Resting blood pressure greater than 140/90 mmhg.
- cervical spinal stenosis, diminished sensation and central nervous system involvement,
- previous
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
this study will be conducted to investigate the impact of adding integrated neuromuscular inhibition technique to postural correction exercises in patients with cervicogenic headache
Read the detailed description
Cervicogenic headache (CeH) is a secondary headache attributed to dysfunctions of the cervical spine. CGH is a non-throbbing, unilateral, side locked headache that originates in the cervical spine and gradually spreads to the occipital, temporal and orbital areas. It is associated with neck pain or stiffness and is often aggravated by sustained neck postures, repeated neck movements or physical activity. INIT is effective as it causes sustained or intermittent compression which causes ischemia reduces local circulation until pressure is released, after which a flushing of fresh oxygenated blood occurs. Mechanoreceptors impulses interface with slower pain messages reducing amount of pain messges reaching the brain, releasing pain relieving hormones, decreasing myofascial pain. Stretches the taut bands of muscles fibers. INIT along with strengthening excercises proved to be beneficial in decreasing disability improving Range of motion.
- Conditions
- Cervicogenic Headache
- Being tested
- Integrated Neuromuscular Inhibition Technique, Postural Correction Exercise
- Keywords
- integrated neuromuscular inhibition technique, postural correction exercises, cervicogenic headache
- Medical subject headings
- Post-Traumatic Headache
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Integrated Neuromuscular Inhibition TechniqueOther
Patients will receive integrated neuromuscular inhibition technique in the form of intermittent ischemic compression, strain counterstrain, and muscle energy technique plus postural correction exercises
Postural Correction ExerciseOther
The exercise program will be in the form of stretching exercises for the sternocleidomastoids (SCM), the scalenes, and upper fibers of trapezius; strengthening isometric exercises for the neck flexors, extensors, lateral flexors, and neck rotators; and postural correction exercises.
| Study group | Role | What they receive |
|---|---|---|
| Integrated Neuromuscular Inhibition Technique | Experimental | Forty-five patients will receive integrated neuromuscular inhibition technique plus postural correction exercises three times a week for six weeks Receives: Other: Integrated Neuromuscular Inhibition Technique; Other: Postural Correction Exercise |
| Postural Correction Exercise | Active comparator | Forty-five patients will receive postural correction exercises three times a week for six weeks Receives: Other: Postural Correction Exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
pain intensity
visual analogue scale will be used to asses pain intensity which patient will be instructed to put point on line from no pain to tolerable pain. The scale consists of a line, usually 100 mm long, ranging from no pain or discomfort (zero) , to the worst pain that could possibly feel .
Measured: up to six weeks
headache disability
The Headache spesific Disability Questionnaire was used to assess headcahe disability. it is a self-administered scale with 9 items that assesses pain intensity, work or school disruptions, and the effect on recreational activities in individuals with headache complaints. Higher scores reflect greater impairment.
Measured: up to 6 weeks
Secondary outcomes (5)
pressure pain threshold
pressure pain threshold pressure pain threshold will be assessed by commander algometer
Measured: up to 6 weeks
cervical range of motion
range of motion will be measured by inclinometer CROM. The CROM (deluxe version - Performance Attainment Associates, Roseville, MN, USA) measures the cervical range of motion5- for fexion, extension, lateral fexion, and rotation using separate inclinometers. These inclinometers are attached to a frame similar to that for eyeglasses one in the sagittal plane for fexion - extension, second in the frontal plane for lateral fexion and a third in the horizontal plane for rotation.
Measured: up to 6 weeks
headache frequency
the number of days the subjects feel headache (headache frequency).
Measured: up to six weeks
medication intake
from the patients' diary in the last week , medications intake will be recorded as follow: 1) not at all; 2) once a week; 3) once every couple of days; 4) once or twice a day; or 5) three or more times a day
Measured: up to six weeks
headache duration
the total hours of headache (headache duration).
Measured: up to six weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jul 2025
- Study start30 Jul 2025 (estimated)
- Primary completion25 Feb 2026 (estimated)
- Study completion25 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cervicogenic HeadacheStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- integrated neuromuscular inhibition technique and postural correction exercises
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 90 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Al Shaymaa Shaaban Abd El Azeim, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07086898
- Sponsor's protocol ID
- P.T.REC/012/005850
- Acronym
- CGH
- Status last verified
- Jul 2025
- First submitted
- 18 Jul 2025
- Last updated
- 25 Jul 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Adding Integrated Neuromuscular Inhibition Technique to Postural Correction Exercises in Patients With Cervicogenic Headache
- ClinicalTrials.gov ID
- NCT07086898
- Acronym / sponsor ID
- CGH / P.T.REC/012/005850
- Conditions
- Cervicogenic Headache
- Keywords
- integrated neuromuscular inhibition technique, postural correction exercises, cervicogenic headache
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 90 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 30 Jul 2025 (estimated)
- Primary completion
- 25 Feb 2026 (estimated)
- Study completion
- 25 Feb 2026 (estimated)
- First posted
- 25 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
this study will be conducted to investigate the impact of adding integrated neuromuscular inhibition technique to postural correction exercises in patients with cervicogenic headache
Detailed description
Cervicogenic headache (CeH) is a secondary headache attributed to dysfunctions of the cervical spine. CGH is a non-throbbing, unilateral, side locked headache that originates in the cervical spine and gradually spreads to the occipital, temporal and orbital areas. It is associated with neck pain or stiffness and is often aggravated by sustained neck postures, repeated neck movements or physical activity. INIT is effective as it causes sustained or intermittent compression which causes ischemia reduces local circulation until pressure is released, after which a flushing of fresh oxygenated blood occurs. Mechanoreceptors impulses interface with slower pain messages reducing amount of pain messges reaching the brain, releasing pain relieving hormones, decreasing myofascial pain. Stretches the taut bands of muscles fibers. INIT along with strengthening excercises proved to be beneficial in decreasing disability improving Range of motion.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- integrated neuromuscular inhibition technique and postural correction exercises
| Arm | Type | Receives |
|---|---|---|
| Integrated Neuromuscular Inhibition Technique | Experimental | Other: Integrated Neuromuscular Inhibition Technique, Other: Postural Correction ExerciseForty-five patients will receive integrated neuromuscular inhibition technique plus postural correction exercises three times a week for six weeks |
| Postural Correction Exercise | Active comparator | Other: Postural Correction ExerciseForty-five patients will receive postural correction exercises three times a week for six weeks |
Who may qualify
- Ages
- 20 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- 20 to 60 years old patient with unilaterally of the head pain
- pain triggered by external pressure over the upper cervical joints (c1-c3)
- pain elicited by the neck movements, and/or sustained awkward positions with reduced neck ROM
- headache intensity pain score of at least 20mm on the Visual analogue scale (VAS)
- headache frequency of at least once a week for at least 3 months
Key exclusion criteria (5 listed)
- Migraine, tension- type headache, tumor, osteoporosis, fracture, rheumatoid arthritis and metabolic diseases.
- Prolonged history of steroid use.
- Resting blood pressure greater than 140/90 mmhg.
- cervical spinal stenosis, diminished sensation and central nervous system involvement,
- previous
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Integrated Neuromuscular Inhibition TechniquePatients will receive integrated neuromuscular inhibition technique in the form of intermittent ischemic compression, strain counterstrain, and muscle energy technique plus postural correction exercises | Other | Integrated Neuromuscular Inhibition Technique |
| Postural Correction ExerciseThe exercise program will be in the form of stretching exercises for the sternocleidomastoids (SCM), the scalenes, and upper fibers of trapezius; strengthening isometric exercises for the neck flexors, extensors, lateral flexors, and neck rotators; and postural correction exercises. | Other | Integrated Neuromuscular Inhibition Technique, Postural Correction Exercise |
Primary outcome
pain intensity
Time frame: up to six weeks
visual analogue scale will be used to asses pain intensity which patient will be instructed to put point on line from no pain to tolerable pain. The scale consists of a line, usually 100 mm long, ranging from no pain or discomfort (zero) , to the worst pain that could possibly feel .
headache disability
Time frame: up to 6 weeks
The Headache spesific Disability Questionnaire was used to assess headcahe disability. it is a self-administered scale with 9 items that assesses pain intensity, work or school disruptions, and the effect on recreational activities in individuals with headache complaints. Higher scores reflect greater impairment.
5 secondary outcomes
pressure pain threshold
Time frame: up to 6 weeks
cervical range of motion
Time frame: up to 6 weeks
headache frequency
Time frame: up to six weeks
medication intake
Time frame: up to six weeks
headache duration
Time frame: up to six weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Integrated Neuromuscular Inhibition Technique and Postural Correction Exercise in people with Cervicogenic Headache, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 25 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact alshaymaa abd elazeim, phd (01033771553, alshaymaa.shaaban@pt.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
pain intensity (time frame: up to six weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jul 2025.