AcupunctureNCT07110545
Acupuncture on Postoperative Pain Relief in Patients Undergoing Laparoscopic Cholecystectomy
A study testing Acupuncture in people with Acupuncture and Postoperative Pain Management, run by Suez Canal University at 1 site in Egypt.
Trial summary
To lessen related side effects, opioids are used as needed to treat pain after laparoscopic cholecystectomy (LC). Research into the efficacy of acupuncture as an adjunct treatment for postoperative patients has gained traction. However, the findings of these studies are inconsistent. Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Acupuncture, Postoperative Pain Management, Cholecystectomy, Laparoscopic
- What is being tested?
- Acupuncture
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Jan 2024to 30 Mar 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients who are undergoing laparoscopic cholecystectomy of both sexes.
- Patients with grades I and II from the American Society of Anesthesiologists (ASA).
Who cannot join
- Patients with local skin infections at acupoints.
- Patients who have nerve injuries on upper limbs or lower limbs.
- Patients who are alcoholics.
- Pregnant.
- Patients with other severe systemic diseases and serious mental illnesses.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Acupuncture on Postoperative Pain Relief in Patients Undergoing Laparoscopic Cholecystectomy in Suez Canal University Hospitals: A Randomized Controlled Trial
To lessen related side effects, opioids are used as needed to treat pain after laparoscopic cholecystectomy (LC). Research into the efficacy of acupuncture as an adjunct treatment for postoperative patients has gained traction. However, the findings of these studies are inconsistent. It has been suggested that acupuncture may not influence postoperative pain, whereas studies involving various surgical procedures have reported favorable results. Nonetheless, there is scant evidence demonstrating the effectiveness of acupuncture in managing pain following LC. In order to assess the effectiveness and safety of acupuncture in reducing postoperative pain in patients following LC, this study was created.
The study's objective was to reduce postoperative pain in order to improve the results of LC surgeries.
Fifty patients participated in this prospective randomized controlled interventional study, split equally between two groups.
Read the detailed description
One common minimally invasive surgical technique is laparoscopy, where minimizing postoperative pain and nausea and vomiting is of utmost importance. It necessitates early patient mobilization and short-term discharge due to its outpatient characteristics. With over 80% of surgical patients experiencing postoperative pain of varying intensities, postoperative pain presents a significant challenge for clinicians. One of the main reasons why hospital stays are prolonged is postoperative pain.
A number of pharmacological and nonpharmacological approaches, including transversus abdominis plane block, low-pressure pneumoperitoneum, and local anesthetics, have been clinically investigated to treat pain following LC; these approaches require additional research. Effective analgesics that are frequently used in the postoperative surgical phase are nonsteroidal anti-inflammatory drugs (NSAIDs). The use of NSAIDs may be restricted due to the associated risks of gastrointestinal harm and possible postoperative complications, such as bleeding, anastomotic leaks, and soft tissue infection.
Opioids are used as needed to treat pain following LC in order to prevent associated side effects.
Research on acupuncture's effectiveness as a postoperative adjuvant treatment has grown in popularity. The studies' findings, however, are not entirely consistent. Although studies using various surgical procedures produced positive results, it was suggested that acupuncture has no effect on postoperative pain. However, there is scant evidence regarding acupuncture's ability to manage pain following LC. Therefore, the purpose of this study was to investigate the safety and effectiveness of acupuncture in treating postoperative pain in patients following LC. Therefore, the study's goal was to reduce postoperative pain in order to enhance the results of LC surgeries.
Fifty patients, equally split into two groups, participated in this prospective randomized controlled interventional study.
- There were 25 patients in Group I (Interventional group) who received acupuncture.
- 25 patients in Group II (control patients) did not receive any intervention.
- Being tested
- Acupuncture
- Keywords
- acupuncture, postoperative pain
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AcupunctureOther
Application of acupuncture on specific acupoints
| Study group | Role | What they receive |
|---|---|---|
| Acupuncture | Active comparator | Interventional group: included 25 patients for Acupuncture Receives: Other: Acupuncture |
| Control | No intervention | Control patients: included 25 patients who received no intervention. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Post-operative pethidine
The total amount of pethidine required to manage pain following surgery
Measured: From the moment the surgery was completed until 24 hours after the procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Aug 2025
- Study start15 Jan 2024
- Primary completion1 Nov 2024
- Study completion30 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AcupunctureStudies of the same condition, open and under way.
- More trials run by Suez Canal UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Suez Canal University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Abdelrhman Alshawadfy, Suez Canal University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07110545
- Sponsor's protocol ID
- acupunture in cholecystectomy
- Status last verified
- Jul 2025
- First submitted
- 31 Jul 2025
- Last updated
- 7 Aug 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Acupuncture on Postoperative Pain Relief in Patients Undergoing Laparoscopic Cholecystectomy in Suez Canal University Hospitals: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07110545
- Acronym / sponsor ID
- acupunture in cholecystectomy
- Keywords
- acupuncture, postoperative pain
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Suez Canal UniversityUniversity, hospital or other
- Study start
- 15 Jan 2024 (actual)
- Primary completion
- 1 Nov 2024 (actual)
- Study completion
- 30 Mar 2025 (actual)
- First posted
- 7 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To lessen related side effects, opioids are used as needed to treat pain after laparoscopic cholecystectomy (LC). Research into the efficacy of acupuncture as an adjunct treatment for postoperative patients has gained traction. However, the findings of these studies are inconsistent. It has been suggested that acupuncture may not influence postoperative pain, whereas studies involving various surgical procedures have reported favorable results. Nonetheless, there is scant evidence demonstrating the effectiveness of acupuncture in managing pain following LC. In order to assess the effectiveness and safety of acupuncture in reducing postoperative pain in patients following LC, this study was created.
The study's objective was to reduce postoperative pain in order to improve the results of LC surgeries.
Fifty patients participated in this prospective randomized controlled interventional study, split equally between two groups.
Detailed description
One common minimally invasive surgical technique is laparoscopy, where minimizing postoperative pain and nausea and vomiting is of utmost importance. It necessitates early patient mobilization and short-term discharge due to its outpatient characteristics. With over 80% of surgical patients experiencing postoperative pain of varying intensities, postoperative pain presents a significant challenge for clinicians. One of the main reasons why hospital stays are prolonged is postoperative pain.
A number of pharmacological and nonpharmacological approaches, including transversus abdominis plane block, low-pressure pneumoperitoneum, and local anesthetics, have been clinically investigated to treat pain following LC; these approaches require additional research. Effective analgesics that are frequently used in the postoperative surgical phase are nonsteroidal anti-inflammatory drugs (NSAIDs). The use of NSAIDs may be restricted due to the associated risks of gastrointestinal harm and possible postoperative complications, such as bleeding, anastomotic leaks, and soft tissue infection.
Opioids are used as needed to treat pain following LC in order to prevent associated side effects.
Research on acupuncture's effectiveness as a postoperative adjuvant treatment has grown in popularity. The studies' findings, however, are not entirely consistent. Although studies using various surgical procedures produced positive results, it was suggested that acupuncture has no effect on postoperative pain. However, there is scant evidence regarding acupuncture's ability to manage pain following LC. Therefore, the purpose of this study was to investigate the safety and effectiveness of acupuncture in treating postoperative pain in patients following LC. Therefore, the study's goal was to reduce postoperative pain in order to enhance the results of LC surgeries.
Fifty patients, equally split into two groups, participated in this prospective randomized controlled interventional study.
- There were 25 patients in Group I (Interventional group) who received acupuncture.
- 25 patients in Group II (control patients) did not receive any intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Acupuncture | Active comparator | Other: AcupunctureInterventional group: included 25 patients for Acupuncture |
| Control | No intervention | –Control patients: included 25 patients who received no intervention. |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Patients who are undergoing laparoscopic cholecystectomy of both sexes.
- Patients with grades I and II from the American Society of Anesthesiologists (ASA).
Key exclusion criteria (5 listed)
- Patients with local skin infections at acupoints.
- Patients who have nerve injuries on upper limbs or lower limbs.
- Patients who are alcoholics.
- Pregnant.
- Patients with other severe systemic diseases and serious mental illnesses.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AcupunctureApplication of acupuncture on specific acupoints | Other | Acupuncture |
Primary outcome
Post-operative pethidine
Time frame: From the moment the surgery was completed until 24 hours after the procedure
The total amount of pethidine required to manage pain following surgery
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Aug 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Acupuncture in people with Acupuncture and Postoperative Pain Management, run by Suez Canal University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Post-operative pethidine (time frame: From the moment the surgery was completed until 24 hours after the procedure). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Aug 2025.