WristNCT07122375
Angle-Specific Torque Profile Analysis in the Wrist Joint
An observational study of Wrist and Reliability, run by Gazi University.
Trial summary
The wrist joint performs various tasks at multiple angles during daily activities, both in flexion and extension positions. Among the parameters that facilitate these tasks, strength-particularly in relation to coordination and motor control-plays a key role. Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Wrist, Reliability, Torque
- What is being tested?
- Angle Specific Torque Profile Analysis
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- 1 Sep 2025to 1 Dec 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Healthy young adult participants
Who may be able to join
- Healthy young adult participants
Who cannot join
- Participants who were unable to complete the target range of motion
- Participants with missing data
About this study
Official title: Reliability and Normative Results of Angle-Specific Torque Profile Analysis in the Wrist Joint
The wrist joint performs various tasks at multiple angles during daily activities, both in flexion and extension positions. Among the parameters that facilitate these tasks, strength-particularly in relation to coordination and motor control-plays a key role. Therefore, identifying potential strength deficits is important for maintaining the continuity of daily functional tasks. In the literature, a wide range of methods exist for evaluating strength, from manual tests to advanced technological devices (references). One such method, isokinetic dynamometry, is considered among the most reliable due to its ability to provide objective and standardized measurements across different types of muscle contractions (isometric, isotonic, and isokinetic). Isokinetic dynamometers yield various data including peak torque, average torque, total work, fatigue index, and torque slope. Researchers frequently interpret findings based on peak or average torque values generated during isokinetic contractions. These torque measures provide an overall representation of strength during a given movement.
In wrist movements, rather than a single muscle, muscle groups are responsible for executing motion. However, when only peak or average torque at a single joint angle is assessed, the presence or absence of weakness in the movement can be detected, but it offers limited information. If weakness exists, identifying the specific joint angle at which it occurs can provide more direct insights into which muscles may be impaired. Furthermore, angle-specific profiling allows for characterization of muscle behavior throughout the movement, offering valuable information about potential kinematic disruptions. Having normative data on these profiles enables the detection of deviations from typical patterns across the full range of motion, which can be beneficial for both diagnosis and treatment planning.
Read more
However, to derive such benefits, it is critical that the data be obtained using reliable methods. Reliability refers to the degree to which an instrument or technique yields consistent results across repeated measurements, and is a prerequisite for usability. Statistical Parametric Mapping (SPM) is an increasingly popular method that enables angle-specific torque analysis, providing clinically and scientifically meaningful information on muscle strength. Angle-specific mapping is considered the "gold standard" because it presents torque values across the entire joint range, eliminating the need for interpolation between angles. For example, during daily activities, the wrist joint commonly operates within a range from 40° extension to 38° flexion. Therefore, measuring strength at only one joint angle may not be sufficient to reflect the potential limitations experienced in everyday tasks.
Despite its advantages, no reliability study involving SPM analysis has been found for the wrist joint. Furthermore, there is currently no study providing normative data for SPM-based analysis in the wrist. The aim of this study is to examine the reliability of angle-specific torque profile analysis during wrist flexion and extension movements and to provide normative data for healthy young adults.
- Conditions
- Wrist, Reliability, Torque, Isokinetic
- Being tested
- Angle Specific Torque Profile Analysis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Angle Specific Torque Profile AnalysisDiagnostic test
All assessment data will be obtained from the archival records of young healthy adults, and no new assessments will be conducted. Raw data from wrist flexion and extension evaluations performed using an isokinetic dynamometer will be utilized.
What is being measured
The primary outcome is the main question the study is designed to answer.
Angle Specific Torque Profile Analysis
Raw data from the system files of the isokinetic dynamometer of both extremities of the participants who meet the criteria will be collected. SPM analysis of these raw data will be performed using the open source spm1d package in Matlab (R2021b, The Mathworks Inc, Natick, MA) software. Thus, the torque/angle data generated by the movements of both extremities through the range of motion set in the isokinetic dynamometer will be divided into 101 slices and angle-dependent torque graphs will be generated (SPM analysis). SPM analysis will be performed for wrist flexors and extensors. As a result of this analysis, the angle-dependent torque characteristics of both wrists and unilateral angle-dependent agonist/antagonist torque characteristics will be examined.
Measured: 4 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2025
- Study start1 Sep 2025 (estimated)
- Primary completion1 Dec 2025 (estimated)
- Study completion1 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for WristStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Gazi University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Barış SEVEN, Gazi University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07122375
- Sponsor's protocol ID
- 9
- Status last verified
- Aug 2025
- First submitted
- 30 Jul 2025
- Last updated
- 14 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 14 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Reliability and Normative Results of Angle-Specific Torque Profile Analysis in the Wrist Joint
- ClinicalTrials.gov ID
- NCT07122375
- Acronym / sponsor ID
- 9
- Conditions
- Wrist, Reliability, Torque, Isokinetic
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Gazi UniversityUniversity, hospital or other
- Study start
- 1 Sep 2025 (estimated)
- Primary completion
- 1 Dec 2025 (estimated)
- Study completion
- 1 Dec 2025 (estimated)
- First posted
- 14 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The wrist joint performs various tasks at multiple angles during daily activities, both in flexion and extension positions. Among the parameters that facilitate these tasks, strength-particularly in relation to coordination and motor control-plays a key role. Therefore, identifying potential strength deficits is important for maintaining the continuity of daily functional tasks. In the literature, a wide range of methods exist for evaluating strength, from manual tests to advanced technological devices (references). One such method, isokinetic dynamometry, is considered among the most reliable due to its ability to provide objective and standardized measurements across different types of muscle contractions (isometric, isotonic, and isokinetic). Isokinetic dynamometers yield various data including peak torque, average torque, total work, fatigue index, and torque slope. Researchers frequently interpret findings based on peak or average torque values generated during isokinetic contractions. These torque measures provide an overall representation of strength during a given movement.
In wrist movements, rather than a single muscle, muscle groups are responsible for executing motion. However, when only peak or average torque at a single joint angle is assessed, the presence or absence of weakness in the movement can be detected, but it offers limited information. If weakness exists, identifying the specific joint angle at which it occurs can provide more direct insights into which muscles may be impaired. Furthermore, angle-specific profiling allows for characterization of muscle behavior throughout the movement, offering valuable information about potential kinematic disruptions. Having normative data on these profiles enables the detection of deviations from typical patterns across the full range of motion, which can be beneficial for both diagnosis and treatment planning.
However, to derive such benefits, it is critical that the data be obtained using reliable methods. Reliability refers to the degree to which an instrument or technique yields consistent results across repeated measurements, and is a prerequisite for usability. Statistical Parametric Mapping (SPM) is an increasingly popular method that enables angle-specific torque analysis, providing clinically and scientifically meaningful information on muscle strength. Angle-specific mapping is considered the "gold standard" because it presents torque values across the entire joint range, eliminating the need for interpolation between angles. For example, during daily activities, the wrist joint commonly operates within a range from 40° extension to 38° flexion. Therefore, measuring strength at only one joint angle may not be sufficient to reflect the potential limitations experienced in everyday tasks.
Despite its advantages, no reliability study involving SPM analysis has been found for the wrist joint. Furthermore, there is currently no study providing normative data for SPM-based analysis in the wrist. The aim of this study is to examine the reliability of angle-specific torque profile analysis during wrist flexion and extension movements and to provide normative data for healthy young adults.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Healthy young adult participants
Key inclusion criteria (1 listed)
- Healthy young adult participants
Key exclusion criteria (2 listed)
- Participants who were unable to complete the target range of motion
- Participants with missing data
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Angle Specific Torque Profile AnalysisAll assessment data will be obtained from the archival records of young healthy adults, and no new assessments will be conducted. Raw data from wrist flexion and extension evaluations performed using an isokinetic dynamometer will be utilized. | Diagnostic test | – |
Primary outcome
Angle Specific Torque Profile Analysis
Time frame: 4 months
Raw data from the system files of the isokinetic dynamometer of both extremities of the participants who meet the criteria will be collected. SPM analysis of these raw data will be performed using the open source spm1d package in Matlab (R2021b, The Mathworks Inc, Natick, MA) software. Thus, the torque/angle data generated by the movements of both extremities through the range of motion set in the isokinetic dynamometer will be divided into 101 slices and angle-dependent torque graphs will be generated (SPM analysis). SPM analysis will be performed for wrist flexors and extensors. As a result of this analysis, the angle-dependent torque characteristics of both wrists and unilateral angle-dependent agonist/antagonist torque characteristics will be examined.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Aug 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Wrist and Reliability, run by Gazi University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Angle Specific Torque Profile Analysis (time frame: 4 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Aug 2025.