Sexual FunctioningESFTMGAPNCT07131267
Evaluating Sexual Functioning in Trans Men During the Gender Affirmation Process: A Mixed Methods Study
An observational study of Sexual Functioning and Transgender Men, run by Eskisehir Osmangazi University at 1 site in Turkey (Türkiye).
Trial summary
Both sexual experiences and the process of gender transition initiated to reduce gender dysphoria carry cultural characteristics. Gender categories, societal expectations for each gender, and attitudes toward sexual minorities in a given society can shape the lived experiences of trans individuals. Read more about this study
- Who is it for?
- Ages 18 to 65 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Sexual Functioning, Transgender Men, Gender Affirmation Surgery
- How many people
- 52 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 5 Aug 2025to 31 Dec 2026
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Study population: Trans men during the gender affirmation process
Who may be able to join
- 18 years or older Diagnosed with gender dysphoria by two different physicians Getting medical support for the gender affirmation process
Who cannot join
- Over 65 years Diagnosed with intellectual disability, dementia, or organic mental disorders Having a systemic disease that negatively impacts sexual function Getting a score above 3 on the Clinical Global Impression Scale
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Imran G Yilmaz-Karaman, Assoc.Prof. contact
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Eskişehir Osmangazi University, Faculty of Medicine, Department of Psychiatry
Eskişehir, Türkiye, 26040
Imran G Yilmaz-Karaman, Assoc.Prof., 00902222392979 ext. 3604, imrangokcen.yilmazkaraman@ogu.edu.tr
Aylin Aydin, Assisst.Dr., 00902222392979 ext. 3600, dr.aylinaydin@gmail.com
About this study
Both sexual experiences and the process of gender transition initiated to reduce gender dysphoria carry cultural characteristics. Gender categories, societal expectations for each gender, and attitudes toward sexual minorities in a given society can shape the lived experiences of trans individuals. Therefore, research on individuals with gender dysphoria in different cultural contexts is of great importance. To our knowledge, no study in Türkiye has examined sexual functioning in trans individuals undergoing gender transition. For this reason, our study aimed to investigate how sexual functioning is affected by the gender transition process in trans men with gender dysphoria, using both quantitative and qualitative methods.
Read the detailed description
For the quantitative part of the study, 52 participants will receive a sociodemographic and clinical data form, Arizona Sexual Experiences Scale, Sexual Desire Inventory, Utrecht Gender Dysphoria Scale, Depression Anxiety Stress Scale-21, and WHOQOL-100 sexual quality of life subscale.
While performing a qualitative study, 12 participants will receive questions about their sexual functioning during the gender affirmation process.
- Keywords
- sexual functioning, transgender men, gender affirmation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Study group | Trans men during the gender affirmation process |
What is being measured
The primary outcome is the main question the study is designed to answer.
Sexual functioning
Arizona Sexual Experience Scale: It is designed to measure five specific items identified as fundamental elements of sexual function. The scale was designed by McGahuey (McGahuey et al., 1997). The Turkish validity and reliability of the scale was conducted by Atilla Soykan (Soykan, 2004). Higher scores indicate higher levels of dysfunction.
Measured: Day 1
Sexual desire
Sexual Desire Inventory-2: It is a 14-item, self-administered questionnaire measuring sexual desire (Spector et al., 1996). It includes subscales of sexual motivation, sexual satisfaction, sexual relationship quality, activity frequency, and behavioral diversity to capture the multidimensional nature of sexual desire. The Turkish validity and reliability of the scale, along with other languages, were conducted in Castro-Calvo's study (Castro-Calvo et al., 2024). High scores indicate high sexual desire.
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Aug 2025
- Study start5 Aug 2025
- Primary completion30 Apr 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Sexual FunctioningStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 52 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Eskisehir Osmangazi University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Imran Gokcen Yilmaz-Karaman, Eskisehir Osmangazi University
- Investigators
- Imran G Yilmaz-Karaman, Assoc.Prof., Study director, Eskişehir Osmangazi University, Faculty of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07131267
- Sponsor's protocol ID
- EskisehirOU 28.05.2025/26
- Acronym
- ESFTMGAP
- Status last verified
- Aug 2025
- First submitted
- 4 Aug 2025
- Last updated
- 20 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluating Sexual Functioning in Trans Men During the Gender Affirmation Process: A Mixed Methods Study
- ClinicalTrials.gov ID
- NCT07131267
- Acronym / sponsor ID
- ESFTMGAP / EskisehirOU 28.05.2025/26
- Keywords
- sexual functioning, transgender men, gender affirmation
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Eskisehir Osmangazi UniversityUniversity, hospital or other
- Study start
- 5 Aug 2025 (actual)
- Primary completion
- 30 Apr 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 20 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Both sexual experiences and the process of gender transition initiated to reduce gender dysphoria carry cultural characteristics. Gender categories, societal expectations for each gender, and attitudes toward sexual minorities in a given society can shape the lived experiences of trans individuals. Therefore, research on individuals with gender dysphoria in different cultural contexts is of great importance. To our knowledge, no study in Türkiye has examined sexual functioning in trans individuals undergoing gender transition. For this reason, our study aimed to investigate how sexual functioning is affected by the gender transition process in trans men with gender dysphoria, using both quantitative and qualitative methods.
Detailed description
For the quantitative part of the study, 52 participants will receive a sociodemographic and clinical data form, Arizona Sexual Experiences Scale, Sexual Desire Inventory, Utrecht Gender Dysphoria Scale, Depression Anxiety Stress Scale-21, and WHOQOL-100 sexual quality of life subscale.
While performing a qualitative study, 12 participants will receive questions about their sexual functioning during the gender affirmation process.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Day
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Study group | – | –Trans men during the gender affirmation process |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Trans men during the gender affirmation process
Key inclusion criteria (1 listed)
- 18 years or older Diagnosed with gender dysphoria by two different physicians Getting medical support for the gender affirmation process
Key exclusion criteria (1 listed)
- Over 65 years Diagnosed with intellectual disability, dementia, or organic mental disorders Having a systemic disease that negatively impacts sexual function Getting a score above 3 on the Clinical Global Impression Scale
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Sexual functioning
Time frame: Day 1
Arizona Sexual Experience Scale: It is designed to measure five specific items identified as fundamental elements of sexual function. The scale was designed by McGahuey (McGahuey et al., 1997). The Turkish validity and reliability of the scale was conducted by Atilla Soykan (Soykan, 2004). Higher scores indicate higher levels of dysfunction.
Sexual desire
Time frame: Day 1
Sexual Desire Inventory-2: It is a 14-item, self-administered questionnaire measuring sexual desire (Spector et al., 1996). It includes subscales of sexual motivation, sexual satisfaction, sexual relationship quality, activity frequency, and behavioral diversity to capture the multidimensional nature of sexual desire. The Turkish validity and reliability of the scale, along with other languages, were conducted in Castro-Calvo's study (Castro-Calvo et al., 2024). High scores indicate high sexual desire.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Aug 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Imran G Yilmaz-Karaman, Assoc.Prof. contact
Imran G Yilmaz-Karaman, Assoc.Prof. study director
Eskişehir Osmangazi University, Faculty of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Sexual Functioning and Transgender Men, run by Eskisehir Osmangazi University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 20 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Imran G Yilmaz-Karaman, Assoc.Prof. (02222392979 ext. 3600, imrangokcen.yilmazkaraman@ogu.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Sexual functioning (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Aug 2025.