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Painless AbortionAAS-PANCT07132151

Reinforcement Learned Automated Anesthesia Systems During Painless Abortion

A study testing General Anesthesia in people with Painless Abortion and Artificial Intelligence (AI), run by Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd. at 8 sites in China.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
Search all trials

Trial summary

This study compares the automated anesthesia systems for painless abortion (AAS-PA) with traditional anesthesia in painless abortions. It assesses intraoperative indicators (hypoxemia, injection pain, hypotension, hemodynamics, respiratory depression) and postoperative outcomes (nausea, dizziness, recovery time… Read more about this study

Who is it for?
Ages 18 to 45 years, women onlyHealthy volunteers can take part
What is being tested?
General Anesthesia
Type of treatment
Surgery or procedure
Could I receive a placebo?
No, everyone receives an active treatment
How many people
167 participants
Where
8 sitesChina
Study dates
8 Sep 2025to 8 Nov 2027
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 45 years
  • Women only
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Age between 18-45 years
  • ASA status Ⅰ to Ⅱ
  • Diagnosed with early intrauterine pregnancy
  • Body mass index (BMI) between 18 to 28 kg/m2

Who cannot join

  • History of cardiac, hepatic, renal, or metabolic disorders (e.g., diabetes, hypertension, sleep apnea)
  • Known allergy to opioids or ciprofloxacin components
  • Cachexia
  • History of substance or alcohol abuse
  • ASA class III or higher
  • Participation in any other drug clinical trial within the past 3 months
  • Long-term use of sedative or analgesic medications
  • History of neurological disorders and convulsions

Trial locations and contacts

8 sites in 1 country. Contact the study team or a site near you to ask about taking part.

Qingwang Lu contact

+86 13675930836

mxbj-2008@163.com

8 sites in 1 country

China8 sites

  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan

  • The First Affiliated Hospital of Army Medical University

    Chongqing

  • The People's Hospital of Yubei District of Chongqing city

    Chongqing

  • Fujian Provincial Hospital

    Fuzhou, Fujian

  • Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian)

    Jinjiang, Fujian

  • Shishi Hospital

    Quanzhou, Fujian

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong

  • Zhengzhou Central Hospital Affiliated to Zhengzhou University

    Zhengzhou, Henan

Other trials in China

About this study

Official title: Automated Anesthesia Systems for Painless Abortion (AAS-PA): a Multi-center, Randomized Controlled Trial

This study compares the automated anesthesia systems for painless abortion (AAS-PA) with traditional anesthesia in painless abortions. It assesses intraoperative indicators (hypoxemia, injection pain, hypotension, hemodynamics, respiratory depression) and postoperative outcomes (nausea, dizziness, recovery time, satisfaction). The AAS-PA group uses AI-adjusted intravenous ciprofol based on real-time vital signs and sedation depth; the traditional group relies on manual anesthesia. The goal is to verify if AAS-PA safely manages sedation, meets painless standards, reduces adverse events, and improves experience, aiding optimized automated protocols.

Being tested
AI Controlled General Anesthesia, General Anesthesia

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • AI Controlled General AnesthesiaProcedure or surgery

    During painless abortion, anesthesia will be induced using ciprofol, and controlled by an AI model.

  • General AnesthesiaProcedure or surgery

    Anesthesia will be induced using ciprofol, and controlled by experienced anesthesiologists.

Study groups in NCT07132151
Study groupRoleWhat they receive
Test groupExperimentalIn the test group, participants will receive anesthesia via an AI model.
Receives: Procedure: AI Controlled General Anesthesia
Control groupExperimentalIn the control group, anesthesia will be induced by experienced anesthesiologists.
Receives: Procedure: General Anesthesia

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Incidence of Hypoxemia

    Hypoxemia is defined as blood oxygen saturation below 92% at any time.

    Measured: During procedure

Secondary outcomes (10)

  1. Area under curve of hypoxemia

    The area where SpO2 is below 92%.

    Measured: During procedure

  2. Duration of colonoscopy

    Measured: During procedure

  3. Lowest value of blood oxygen saturation

    Measured: During procedure

  4. Induction and maintenance doses of anesthesia

    Doses are recorded in mg/kg/h. The induction period is defined as the interval from the start of anesthesia to the first BIS value below 60. The maintenance period is defined as the interval from the first BIS value below 60 to the end of the drug infusion.

    Measured: During procedure

  5. Ciprofol related adverse reactions

    Included sinus bradycardia, dizziness

    Measured: During procedure

  6. Induction time

    The time interval from the start of drug administration to the first BIS ≤ 1.

    Measured: During procedure

  7. Complete recovery time

    Time interval from cessation of anesthetic agents to BIS > 80.

    Measured: During procedure

  8. Incidence of hypotension

    Systolic blood pressure < 90 mmHg or a 30% decrease from baseline lasting longer than 2 minutes.

    Measured: During procedure

  9. Counts of body movement

    Measured: During procedure

  10. Dose of norepinephrine

    Measured: During procedure

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted20 Aug 2025
  2. Study start8 Sep 2025 (estimated)
  3. Primary completion8 Oct 2025 (estimated)
  4. Study completion8 Nov 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Double blind
Who is masked
Participant, Outcomes assessor
Enrolment
167 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07132151
Sponsor's protocol ID
SZUS2025002
Acronym
AAS-PA
Status last verified
Aug 2025
First submitted
12 Aug 2025
Last updated
20 Aug 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Questions about this trial

What is this clinical trial studying?

A study testing General Anesthesia in people with Painless Abortion and Artificial Intelligence (AI), run by Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd. at 8 sites in China.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 20 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 8 sites in China. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Qingwang Lu (+86 13675930836, mxbj-2008@163.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Incidence of Hypoxemia (time frame: During procedure). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07132151.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Aug 2025.

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