Clinical trials: Ciprofol
Thyroid Disease
The Effective Blood Concentration of Ciprofol
1. Eligible patients were selected and enrolled in the study. 2. General anesthesia was induced using ciprofol in all participants, with standardized evaluation of consciousness levels during induction. 3.
- Trial name
- NCT07294989
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Peking University Shenzhen Hospital
Depressive Disorder
Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients
In this clinical study, propofol was used as the positive control, and a randomized controlled trial design was used to observe the effects of ciprofol anesthesia on learning and memory function and antidepressant efficacy in…
- Trial name
- NCT05266560
- Testing
- ciprofol, Propofol
- Volunteers
- 390 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Tonsillectomy With or Without Adenoidectomy
Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy
To observe the effects of remimazolam versus ciprofol TIVA on PRAE in pediatric tonsillectomy and adenoidectomy.
- Trial name
- NCT07118579
- Testing
- Remimazolam, Propofol, Ciprofol
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Tongji Hospital
Adenotonsillectomy, Propofol
Comparison of Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy
The goal of this clinical trial is to compare the Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy Participants will be randomly allocated to two groups: Ciprofol group (Group C) and Propofol group…
- Conditions
- Adenotonsillectomy, Propofol, Ciprofol
- Trial name
- NCT06882980
- Testing
- Ciprofol group, Propofol group
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
At the initiation of induction for non-intubated general anesthesia, ciprofol or propofol will be administered intravenously at a rate of 10 mL/min.
- Trial name
- NCT07670923
- Testing
- Propofol Injection, Ciprofol Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- General Hospital of Ningxia Medical University
Hemodynamics, Postoperative Recovery
Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery
To study the Effect of Ciprofol Infusion for Induction and Maintenance of anesthesia on Hemodynamics and Postoperative Recovery in Patients Undergoing Thoracoscopic Lobectomy:a randomized, controlled trial.
- Conditions
- Hemodynamics, Postoperative Recovery, Anesthesia
- Trial name
- NCT05664386
- Testing
- propofol, ciprofol
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Xiumei Song
Intubation, Intratracheal, Adverse Effects
The Study of Ciprofol for the Suppression of Cardiovascular Responses to Tracheal Intubation
Preliminary studies have illuminated the promising nature of ciprofol, indicating its enhanced safety spectrum, superior potency, and a diminished likelihood of experiencing injection-related discomfort.
- Trial name
- NCT06095570
- Testing
- Ciprofol, Remimazolam
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Hainan Medical University
Gastric Cancer, Gastric Ulcer
Dose Exploration of Ciprofol for Sedation in Gastrointestinal Endoscopic Diagnosis and Treatment of Obese Patients.
Ciprofol is a new anesthetic, which combines with γ- Aminobutyric acid-a (GABAA) receptor. Ciprofol has shown equivalent anesthetic efficacy of propofol at 1/4 to 1/5 of the dosage.
- Conditions
- Gastric Cancer, Gastric Ulcer, Intestinal Polyps, Intestinal Cancer
- Trial name
- NCT05517408
- Testing
- ciprofol
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Ciprofol
Ciprofol's Influence on LVOT VTI in Elderly Painless Colonoscopy Patients
1. Objective: Primary: Compare the effect of Ciprofol vs Propofol on LVOT VTI at 2 minutes post-injection (T1) in elderly patients (≥65 years).
- Trial name
- NCT07081477
- Testing
- Intravenous Anesthetic Induction with Ciprofol for Painless Colonoscopy in Elderly Patients, Propofol Intravenous Anesthesia Induction for Painless Colonoscopy in Elderly Patients
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Anesthesia
Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial
Ciprofol, a novel intravenous general anesthetic with a chemical structure akin to propofol, boasts significantly enhanced potency.
- Trial name
- NCT06312345
- Testing
- Drug: ciprofol injection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Le Yu
Liver Cancer, Ciprofol
Ciprofol Sedation in Patients Undergoing Liver Cancer Percutaneous Radiofrequency Ablation
Efficacy and Safety of Ciprofol Sedation in Patients Undergoing Liver Cancer Percutaneous Radiofrequency Ablation
- Trial name
- NCT06178926
- Testing
- Propofol, Ciprofol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhejiang Cancer Hospital
ECMO Treatment, ARDS (Acute Respiratory Distress Syndrome)
Ciprofol's Impact on Oxygenator Function in Extracorporeal Membrane Oxygenation (ECMO) Patients
This study evaluates the safety and effectiveness of Ciprofol, a new sedative, in critically ill patients receiving Extracorporeal Membrane Oxygenation (ECMO), a life-support system for heart or lung failure.
- Conditions
- ECMO Treatment, ARDS (Acute Respiratory Distress Syndrome), ECMO and Acute MI, Respiratory Failure Patients Treated With ECMO
- Trial name
- CIP-OXY (NCT06934811)
- Testing
- Ciprofol, Midazolam
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
PND, POCD - Postoperative Cognitive Dysfunction
Effects of Ciprofol on Perioperative Neurocognitive Function in Elderly Patients Undergoing Daytime Surgery
As life expectancy increases, the rate of disability among elderly individuals is also rising. Elderly patients undergoing home-based rehabilitation after surgery without medical supervision may experience complications and…
- Trial name
- NCT07895407
- Testing
- Ciprofol, propofol
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Gynecological Outpatient Surgery
Phase III Clinical Trial Evaluating the Efficacy and Safety of Ciprofol Injection for the Induction of Sedation/Anesthesia in Subjects Undergoing Gynecological Outpatient Surgeries
This study is a multi-center, randomized, double-blind, Propofol parallel-controlled phase III clinical study, with the primary objective of evaluating the efficacy of Ciprofol vs.
- Trial name
- NCT04958746
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Biliary and Pancreatic Diseases, Endoscopic Retrograde Cholangiopancreatography (ERCP)
A 2×2 Factorial Randomized Controlled Trial for ERCP
To investigate the effects of propofol vs. cyclopropofol and sufentanil vs. esketamine on intraoperative hypoxemia and hypotension in elderly patients undergoing ERCP, as well as the interaction between these two factors.
- Trial name
- NCT07584902
- Testing
- Anesthesia induction using propofol+sufentanil, Anesthesia induction using propofol+esketamine, Anesthesia induction using ciprofol+sufentanil
- Volunteers
- 236 people
- Sponsor
- Gang Chen
Bronchoscopy, Procedural Sedation
Ciprofol Versus Propofol With Low-Dose Sufentanil for Painless Bronchoscopy
Bronchoscopy may cause coughing, discomfort, body movement, and changes in breathing or blood pressure. Propofol is commonly used for sedation during bronchoscopy, but it may cause respiratory depression, circulatory depression…
- Trial name
- NCT07744061
- Testing
- Ciprofol, Propofol, Sufentanil
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Central Hospital
Ciprofol, Propofol
Comparing Ciprofol and Propofol for Sedation in Hypotensive ICU Patients: a Single Center Prospective Cohort Study
This study was a single-center, prospective, 2-year observational cohort study. The study subjects were ICU patients requiring vasopressor drugs and requiring sedation.
- Conditions
- Ciprofol, Propofol, Sedation, Low Blood Pressure
- Trial name
- NCT05971121
- Testing
- ciprofol
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Circadian Rhythm, Ciprofol
Effect of Circadian Rhythm on the Sedative Efficacy and Recovery Quality of Ciprofol General Anesthesia: A Multi-Center Observational Study
The goal of this multi-center observational study is to learn about the effect of circadian rhythm (morning vs. afternoon surgery) on the sedative efficacy, hemodynamic stability (especially induction-associated hypotension), and…
- Conditions
- Circadian Rhythm, Ciprofol, Hemodynamic Instability, Anesthetics Adverse Reaction
- Trial name
- NCT07686432
- Testing
- Surgery commences in the morning., Surgery commences in the afternoon.
- Volunteers
- 480 people
- Sponsor
- Jie Chen
Hip Fractures (ICD-10 72.01-72.2), Osteoarthritis, Knee and Hip
Population Pharmacokinetics and Pharmacodynamics of Ciprofol
The goal of this observational study is to learn how the anesthetic drug ciprofol works in older adults who are having limb surgery under general anesthesia at Shanghai Geriatric Medical Center.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Osteoarthritis, Knee and Hip, Femoral Neck Fractures
- Trial name
- NCT07301242
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Geriatric Medical Center
Elective Surgery, Target Controlled Infusion (TCI)
EC50 of Ciprofol Combined With Remifentanil for Inhibiting Tracheal Responses in Patients Undergoing Gynecological Surgery: a Two-phase Up-and-down Sequential Allocation Study
1. The combined induction of intubation with propofol and remifentanil is widely used in clinical anesthesia, primarily through a single intravenous injection.
- Conditions
- Elective Surgery, Target Controlled Infusion (TCI), Noxious Stimuli, Tracheal Intubation Stimulation
- Trial name
- EC50 via TCI (NCT07462949)
- Testing
- Cipofol combined with remifentanil administered via target-controlled infusion
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command