FatigueNCT07137091
Motion for Recovery: The Impact of Gyrokinesis on Childhood Cancer-Related Fatigue.
A study testing Gyrokinesis exercise in people with Fatigue, run by MTI University at 1 site in Egypt.
Trial summary
CRF influences engagement in everyday activities, mood, sleep, social relations, school attendance, academic achievement, and quality of life . It was significantly associated with low health-related quality of life in pediatric cancer patients including leukemia . Read more about this study
- Who is it for?
- Ages 12 to 18 years
- Conditions the study is for
- Fatigue
- What is being tested?
- Gyrokinesis exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Oct 2025to 5 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Diagnosed and treated for a brain tumor during childhood or adolescence (0-≤18 years).
- Treated for a PBT during the previous 10 years, starting from date of diagnosis.
- Aged ≥6 years 0 months at the start of the trial.
- Off therapy/active treatment for pediatric brain tumor (PBT) for 12 months at the start of the trial.
- No known signs of clinical or radiological tumor progression at last follow-up.
- Danish is the sole or primary language (enabling provision of validated assessment tools).
- Patient and family have provided consent for inclusion in the trial.
Who cannot join
- History of recent poorly controlled seizures.
- Motor tics or Tourette syndrome (including family history of tic disorder).
- Known diagnosis of Attention Deficit/Hyperactivity Disorder or Autism Spectrum Disorder.
- Known diagnosis of Full Scale Intelligence Quotient (FSIQ) of <50.
- Pregnancy. Participants known to be pregnant or breastfeeding at screening/registration will not enrolled
Trial locations and contacts
1 site in 1 country.
About this study
CRF influences engagement in everyday activities, mood, sleep, social relations, school attendance, academic achievement, and quality of life . It was significantly associated with low health-related quality of life in pediatric cancer patients including leukemia . Since attention to managing cRF has been drawn, only a few non-pharmacological strategies were tested for their effectiveness in reducing cRF among children. Physical activity (Pa) has been proven to be the most effective strategy . Yet adherence to Pa remains problematic.
Read the detailed description
Childhood cancer-related fatigue (CCRF) is a prevalent condition that affects the quality of life in pediatric cancer patients. Gyrokinesis, a holistic exercise method that incorporates principles from yoga, tai chi, and dance, offers potential benefits in managing fatigue through gentle movement and breath work.
According to The American Cancer Society (ACS) provides comprehensive guidelines for cancer training load .The intensity of the exercise refers to the amount of energy expended when performing the activity4. It can be measured subjectively with a self-reported estimate of effort called the rate of perceived exertion on a scale of 1-10. Low-intensity exercise refers to physical activity or effort performed at 1-3 times the intensity of baseline resting energy expenditure (<3 mets-for example, walking). Moderate-intensity exercise refers to physical activity 3-6 times the intensity of baseline, which requires a moderate amount of effort and noticeably accelerates the heart rate (3-6 mets-for example, brisk walking or cycling). Vigorous-intensity exercise refers to physical activity 6 or more times baseline, which requires a large amount of effort and causes rapid breathing and a substantial increase in heart rate (>6 mets-for example, running or jumping rope)
- Conditions
- Fatigue
- Being tested
- Gyrokinesis exercise
- Medical subject headings
- Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gyrokinesis exerciseOther
- Warm-Up:
- Begin with gentle seated movements to prepare the body.
- Focus on awakening the spine with small circles and undulating motions, coordinating with deep breathing.
- Seated Exercises:
- Perform a series of exercises on a stool or chair.
- Emphasize spinal articulation, pelvic tilts, and side bends while maintaining rhythmic breathing.
- Floor Work:
- Transition to mat-based exercises focusing on core strength and flexibility.
- Incorporate movements like leg lifts, spirals, and arching motions to engage different muscle groups.
- Standing Series:
- Conclude with standing exercises to enhance balance and full-body integration.
- Use spiral movements and weight shifts to energize the body and improve posture.
| Study group | Role | What they receive |
|---|---|---|
| Gyrokinesis exercise | Experimental | Structure of a Gyrokinesis Session
1. Warm-Up:
* Begin with gentle seated movements to prepare the body.
* Focus on awakening the spine with small circles and undulating motions, coordinating with deep breathing.
2. Seated Exercises:
* Perform a series of exercises on a stool or chair.
* Emphasize spinal articulation, pelvic tilts, and side bends while maintaining rhythmic breathing.
3. Floor Work:
* Transition to mat-based exercises focusing on core strength and flexibility.
* Incorporate movements like leg lifts, spirals, and arching motions to engage different muscle groups.
4. Standing Series:
* Conclude with standing exercises to enhance balance and full-body integration.
* Use spiral movements and weight shifts to energize the body and improve posture. Receives: Other: Gyrokinesis exercise |
| control group | No intervention | No intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pediatric quality of life multidimensional fatigue scale (peds QLMFS):
CRF was measured using the valid and reliable Arabic version of peds QlMFs . It is an 18-item questionnaire including 'general fatigue', 'sleep/rest fatigue', and 'cognitive fatigue'. The three child self-report versions were used depending on the child's age: 5-7 years (young child), 8-12 years (child), and 13-18 years (adolescent). Higher scores indicate less intense fatigue symptoms . Before the cOViD-19 pandemic, a paper-based appropriate version of the scale was completed by children. During the pandemic, the questionnaires were offered to the participants through a link sent to the parent's phones to eliminate cross-infection.
Measured: at baseline and at 8 weeks
Secondary outcomes (3)
The six-minute walk test (6-MWT)
The 6-MWt is a functional test that measures the functional capacity/endurance and submaximal or maximal effort needed to perform activities of daily living . The primary outcome of this test is the distance covered in meters. a lower score reflects less functional capacity conceptualizing the child's inability to actively participate in functional activities due to cRF .the test is valid and reliable for children with cancer. Two small cones were placed to mark the starting and end points for a 25-meter-long corridor. The heart rate (hR) and oxygen saturation (spO2) were measured 10 min before and one minute after the 6-MWt according to the guidelines of the American thoracic society (ats).
Measured: at baseline and at 8 weeks
Emotional Well-Being
The Children's Depression Inventory (CDI) is scored by summing the responses to its 27 items, with each item having three options scored 0, 1, or 2, resulting in a total score ranging from 0 to 54. Higher scores indicate more severe depressive symptoms.
Measured: at baseline and at 8 weeks
Blood panel test
Blood samples were collected before and after the experiment to assess changes in serotonin and cortisol levels, as described previously . Venous blood samples (6 mL) were obtained from the antecubital vein using a disposable syringe between 8:00 a.m. and 10:00 a.m. after a fasting period of at least 8 hr. Capillary blood samples were also obtained via the fingertip method, with a minimum volume of 0.3 μL collected for analysis using a portable lactate analyzer. Cortisol can also be measured in the blood, with samples typically taken in the morning when levels peak
Measured: at baseline and at 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Aug 2025
- Study start1 Oct 2025
- Primary completion1 Feb 2026
- Study completion5 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for FatigueStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- RCT
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 80 participants (actual)
Sponsor and investigators
- Lead sponsor
- MTI University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Mohamed Ahmed Abd El hady El Fahl,ph.d, MTI University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07137091
- Sponsor's protocol ID
- P.T.REC/012/005915
- Status last verified
- Feb 2026
- First submitted
- 16 Aug 2025
- Last updated
- 3 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Motion for Recovery: The Impact of Gyrokinesis on Childhood Cancer-Related Fatigue.
- ClinicalTrials.gov ID
- NCT07137091
- Acronym / sponsor ID
- P.T.REC/012/005915
- Conditions
- Fatigue
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 80 participants (actual)
- Lead sponsor
- MTI UniversityUniversity, hospital or other
- Study start
- 1 Oct 2025 (actual)
- Primary completion
- 1 Feb 2026 (actual)
- Study completion
- 5 Feb 2026 (actual)
- First posted
- 22 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
CRF influences engagement in everyday activities, mood, sleep, social relations, school attendance, academic achievement, and quality of life . It was significantly associated with low health-related quality of life in pediatric cancer patients including leukemia . Since attention to managing cRF has been drawn, only a few non-pharmacological strategies were tested for their effectiveness in reducing cRF among children. Physical activity (Pa) has been proven to be the most effective strategy . Yet adherence to Pa remains problematic.
Detailed description
Childhood cancer-related fatigue (CCRF) is a prevalent condition that affects the quality of life in pediatric cancer patients. Gyrokinesis, a holistic exercise method that incorporates principles from yoga, tai chi, and dance, offers potential benefits in managing fatigue through gentle movement and breath work.
According to The American Cancer Society (ACS) provides comprehensive guidelines for cancer training load .The intensity of the exercise refers to the amount of energy expended when performing the activity4. It can be measured subjectively with a self-reported estimate of effort called the rate of perceived exertion on a scale of 1-10. Low-intensity exercise refers to physical activity or effort performed at 1-3 times the intensity of baseline resting energy expenditure (<3 mets-for example, walking). Moderate-intensity exercise refers to physical activity 3-6 times the intensity of baseline, which requires a moderate amount of effort and noticeably accelerates the heart rate (3-6 mets-for example, brisk walking or cycling). Vigorous-intensity exercise refers to physical activity 6 or more times baseline, which requires a large amount of effort and causes rapid breathing and a substantial increase in heart rate (>6 mets-for example, running or jumping rope)
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- RCT
| Arm | Type | Receives |
|---|---|---|
| Gyrokinesis exercise | Experimental | Other: Gyrokinesis exerciseStructure of a Gyrokinesis Session 1. Warm-Up: * Begin with gentle seated movements to prepare the body. * Focus on awakening the spine with small circles and undulating motions, coordinating with deep breathing. 2. Seated Exercises: * Perform a series of exercises on a stool or chair. * Emphasize spinal articulation, pelvic tilts, and side bends while maintaining rhythmic breathing. 3. Floor Work: * Transition to mat-based exercises focusing on core strength and flexibility. * Incorporate movements like leg lifts, spirals, and arching motions to engage different muscle groups. 4. Standing Series: * Conclude with standing exercises to enhance balance and full-body integration. * Use spiral movements and weight shifts to energize the body and improve posture. |
| control group | No intervention | –No intervention |
Who may qualify
- Ages
- 12 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (7 listed)
- Diagnosed and treated for a brain tumor during childhood or adolescence (0-≤18 years).
- Treated for a PBT during the previous 10 years, starting from date of diagnosis.
Key exclusion criteria (5 listed)
- History of recent poorly controlled seizures.
- Motor tics or Tourette syndrome (including family history of tic disorder).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gyrokinesis exercise1. Warm-Up: * Begin with gentle seated movements to prepare the body. * Focus on awakening the spine with small circles and undulating motions, coordinating with deep breathing. 2. Seated Exercises: * Perform a series of exercises on a stool or chair. * Emphasize spinal articulation, pelvic tilts, and side bends while maintaining rhythmic breathing. 3. Floor Work: * Transition to mat-based exercises focusing on core strength and flexibility. * Incorporate movements like leg lifts, spirals, and arching motions to engage different muscle groups. 4. Standing Series: * Conclude with standing exercises to enhance balance and full-body integration. * Use spiral movements and weight shifts to energize the body and improve posture. | Other | Gyrokinesis exercise |
Primary outcome
Pediatric quality of life multidimensional fatigue scale (peds QLMFS):
Time frame: at baseline and at 8 weeks
CRF was measured using the valid and reliable Arabic version of peds QlMFs . It is an 18-item questionnaire including 'general fatigue', 'sleep/rest fatigue', and 'cognitive fatigue'. The three child self-report versions were used depending on the child's age: 5-7 years (young child), 8-12 years (child), and 13-18 years (adolescent). Higher scores indicate less intense fatigue symptoms . Before the cOViD-19 pandemic, a paper-based appropriate version of the scale was completed by children. During the pandemic, the questionnaires were offered to the participants through a link sent to the parent's phones to eliminate cross-infection.
3 secondary outcomes
The six-minute walk test (6-MWT)
Time frame: at baseline and at 8 weeks
Emotional Well-Being
Time frame: at baseline and at 8 weeks
Blood panel test
Time frame: at baseline and at 8 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gyrokinesis exercise in people with Fatigue, run by MTI University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pediatric quality of life multidimensional fatigue scale (peds QLMFS): (time frame: at baseline and at 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Mar 2026.