Hamstring InjuriesNCT07143994
EFFECT OF ECCENTRIC AND CONCENTRIC EXERCISE PROGRAMS For HAMSTRING GRADE INJURIES
A study testing eccentric exercise and concentric exercise in people with Hamstring Injuries, run by Yeditepe University at 1 site in Turkey (Türkiye).
Trial summary
Hamstring injuries are common and recurrent in both elite and recreational athletes, often leading to prolonged absence from sports. The aim of this study is to compare the effects of eccentric and concentric exercise programs on the recovery of elite athletes diagnosed with grade II hamstring strain. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hamstring Injuries
- What is being tested?
- eccentric exercise and concentric exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 20 Feb 2018to 17 Jun 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Participants over 18 ,who are elite athlete and contunie currently active sports life,and . Those with MRI findings showing hamstring grade II strain,who does not have any systemic or mental disease volunteerly participated in the study.
Who cannot join
- Participants who are having severe visual impairment and perception impairment, who has pain preventing to test,who has neurologic problems ans who has a history of injury for 6 months were excluded.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Eccentric vs. Concentric Training: Accelerating Recovery in Elite Athletes With Grade II Hamstring Injury
Hamstring injuries are common and recurrent in both elite and recreational athletes, often leading to prolonged absence from sports. The aim of this study is to compare the effects of eccentric and concentric exercise programs on the recovery of elite athletes diagnosed with grade II hamstring strain. Pain, flexibility, muscle strength, balance, and return-to-sport duration will be evaluated to determine the impact of different exercise modalities. Dynamic balance assessment will also be performed before and after treatment. The two intervention groups will be compared using the Wilcoxon test, with p<0.01 considered statistically significant. This study is expected to provide evidence on which exercise program is more effective in facilitating return to sport and to contribute to improved rehabilitation strategies in future athletic injuries.
Read the detailed description
amstring muscle strain is one of the most common injuries in elite sports, frequently leading to long rehabilitation periods and a high rate of recurrence. Although various treatment modalities have been studied, there is still no consensus on the most effective exercise approach for recovery and return to sport. This study investigates the effectiveness of two different rehabilitation strategies-eccentric exercise programs and concentric exercise programs-in elite athletes diagnosed with grade II hamstring strain.
The intervention will focus on structured exercise protocols applied over a defined treatment period. Outcomes to be assessed include pain intensity, hamstring flexibility, isometric and isotonic muscle strength, dynamic balance, and time to return to sport. Dynamic balance assessment is included as a novel parameter to better understand functional recovery after hamstring injury.
Statistical analysis will be performed using the Wilcoxon test for continuous variables, with p<0.01 considered significant. The results are expected to clarify which type of exercise program provides superior outcomes in terms of functional recovery and safe return to sport. This may help guide clinicians in designing more effective rehabilitation strategies for elite athletes and reduce the recurrence of hamstring injuries.
- Conditions
- Hamstring Injuries
- Being tested
- eccentric exercise, concentric exercise
- Keywords
- grade 2 muscle injury, eccentric exercise, concantric exercise, balance
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
eccentric exerciseOther
This study's interventions are distinguished by the specific application of eccentric and concentric exercise programs tailored for elite athletes with grade II hamstring strains.
concentric exerciseOther
This study's interventions are distinguished by the specific application of eccentric and concentric exercise programs tailored for elite athletes with grade II hamstring strains.
| Study group | Role | What they receive |
|---|---|---|
| Eccentric Exercise Program | Experimental | Elite athletes with grade II hamstring strain will undergo a structured rehabilitation protocol consisting of eccentric strengthening exercises. The program is designed to improve hamstring flexibility, strength, dynamic balance, and facilitate safe return to sport. Receives: Other: eccentric exercise |
| Concentric Exercise Intervention | Experimental | Elite athletes with grade II hamstring strain will undergo a structured rehabilitation protocol consisting of concentric strengthening exercises. The program is designed to enhance hamstring flexibility, muscle strength, dynamic balance, and assist in safe return to sport. Receives: Other: concentric exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Time to Return to Sport
he duration (in days) from the start of the rehabilitation program until the athlete meets all return-to-play criteria, including complete pain relief, sufficient muscle strength, joint mobility, flexibility, running and gait analysis, physical fitness, balance, dynamic functional performance, lumbopelvic motor control, and subjective readiness reported by the athlete.
Measured: From baseline until return to sport, up to 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Aug 2025
- Study start20 Feb 2018
- Primary completion1 Jan 2024
- Study completion17 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hamstring InjuriesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Yeditepe University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Feyza Sule BADILLI HANTAL, Yeditepe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07143994
- Sponsor's protocol ID
- hamstring eccentring
- Status last verified
- Aug 2025
- First submitted
- 20 Aug 2025
- Last updated
- 27 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: A decision regarding the sharing of individual participant data (IPD) has not yet been made. Considerations regarding participant privacy, confidentiality, and the sensitive nature of the data will inform any future decisions on data sharing.
Study at a glance
From the registry record, last updated by the sponsor on 27 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Eccentric vs. Concentric Training: Accelerating Recovery in Elite Athletes With Grade II Hamstring Injury
- ClinicalTrials.gov ID
- NCT07143994
- Acronym / sponsor ID
- hamstring eccentring
- Conditions
- Hamstring Injuries
- Keywords
- grade 2 muscle injury, eccentric exercise, concantric exercise, balance
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Yeditepe UniversityUniversity, hospital or other
- Study start
- 20 Feb 2018 (actual)
- Primary completion
- 1 Jan 2024 (actual)
- Study completion
- 17 Jun 2024 (actual)
- First posted
- 27 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Hamstring injuries are common and recurrent in both elite and recreational athletes, often leading to prolonged absence from sports. The aim of this study is to compare the effects of eccentric and concentric exercise programs on the recovery of elite athletes diagnosed with grade II hamstring strain. Pain, flexibility, muscle strength, balance, and return-to-sport duration will be evaluated to determine the impact of different exercise modalities. Dynamic balance assessment will also be performed before and after treatment. The two intervention groups will be compared using the Wilcoxon test, with p<0.01 considered statistically significant. This study is expected to provide evidence on which exercise program is more effective in facilitating return to sport and to contribute to improved rehabilitation strategies in future athletic injuries.
Detailed description
amstring muscle strain is one of the most common injuries in elite sports, frequently leading to long rehabilitation periods and a high rate of recurrence. Although various treatment modalities have been studied, there is still no consensus on the most effective exercise approach for recovery and return to sport. This study investigates the effectiveness of two different rehabilitation strategies-eccentric exercise programs and concentric exercise programs-in elite athletes diagnosed with grade II hamstring strain.
The intervention will focus on structured exercise protocols applied over a defined treatment period. Outcomes to be assessed include pain intensity, hamstring flexibility, isometric and isotonic muscle strength, dynamic balance, and time to return to sport. Dynamic balance assessment is included as a novel parameter to better understand functional recovery after hamstring injury.
Statistical analysis will be performed using the Wilcoxon test for continuous variables, with p<0.01 considered significant. The results are expected to clarify which type of exercise program provides superior outcomes in terms of functional recovery and safe return to sport. This may help guide clinicians in designing more effective rehabilitation strategies for elite athletes and reduce the recurrence of hamstring injuries.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Eccentric Exercise Program | Experimental | Other: eccentric exerciseElite athletes with grade II hamstring strain will undergo a structured rehabilitation protocol consisting of eccentric strengthening exercises. The program is designed to improve hamstring flexibility, strength, dynamic balance, and facilitate safe return to sport. |
| Concentric Exercise Intervention | Experimental | Other: concentric exerciseElite athletes with grade II hamstring strain will undergo a structured rehabilitation protocol consisting of concentric strengthening exercises. The program is designed to enhance hamstring flexibility, muscle strength, dynamic balance, and assist in safe return to sport. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Participants over 18 ,who are elite athlete and contunie currently active sports life,and . Those with MRI findings showing hamstring grade II strain,who does not have any systemic or mental disease volunteerly participated in the study.
Key exclusion criteria (1 listed)
- Participants who are having severe visual impairment and perception impairment, who has pain preventing to test,who has neurologic problems ans who has a history of injury for 6 months were excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| eccentric exerciseThis study's interventions are distinguished by the specific application of eccentric and concentric exercise programs tailored for elite athletes with grade II hamstring strains. | Other | Eccentric Exercise Program |
| concentric exerciseThis study's interventions are distinguished by the specific application of eccentric and concentric exercise programs tailored for elite athletes with grade II hamstring strains. | Other | Concentric Exercise Intervention |
Primary outcome
Time to Return to Sport
Time frame: From baseline until return to sport, up to 12 weeks
he duration (in days) from the start of the rehabilitation program until the athlete meets all return-to-play criteria, including complete pain relief, sufficient muscle strength, joint mobility, flexibility, running and gait analysis, physical fitness, balance, dynamic functional performance, lumbopelvic motor control, and subjective readiness reported by the athlete.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Aug 2025.
- Individual participant dataSharing planned: Undecided. A decision regarding the sharing of individual participant data (IPD) has not yet been made. Considerations regarding participant privacy, confidentiality, and the sensitive nature of the data will inform any future decisions on data sharing.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing eccentric exercise and concentric exercise in people with Hamstring Injuries, run by Yeditepe University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time to Return to Sport (time frame: From baseline until return to sport, up to 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2025.