Ventilatory FunctionNCT07153562
Effect of Liuzijue Qigong Exercises on Ventilatory Function in Post Stroke Elderly Patients
A study testing liuzijue qigong exercises and conventional rehabilitation treatment in people with Ventilatory Function and Functional Capacity, run by Cairo University at 1 site in Egypt.
Trial summary
to investigate the effect of Liuzijue Qigong exercises on ventilatory function in post stroke elderly patients. Read more about this study
- Who is it for?
- Ages 60 to 80 years
- Conditions the study is for
- Ventilatory Function, Functional Capacity, Motor Function
- What is being tested?
- liuzijue qigong exercises and conventional rehabilitation treatment
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteEgypt
- Study dates
- 25 Aug 2025to 1 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- All patients included in this study met the following criteria:
- Subject people of both sexes (18 women, and 17 men).
- All patients had unilateral stroke.
- Their age ranged from 60 to 80 years old.
- Stroke onset was from 6 to 1 months.
- Medically stable subjects.
- Non-smoker subjects.
- Ability to understand and follow simple verbal instructions.
Who cannot join
- Patients who experienced or had one or more of the following were excluded from the study:
- Patients with severe acute illness.
- Chronic unstable pulmonary and/or cardiac disease.
- Impaired level of consciousness and evidence of gross cognitive problems.
- Patients undergo chemotherapy.
- Active hemoptysis, untreated pneumothorax, recent esophageal surgery.
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- Recent oral, facial or skull trauma / surgery, acute sinusitis, epistaxis, hemodynamic instability.
- Current Smokers.
- Patients had a severe psychological disorder.
Trial locations and contacts
1 site in 1 country.
About this study
to investigate the effect of Liuzijue Qigong exercises on ventilatory function in post stroke elderly patients.
Read the detailed description
70 post stroke patients their ages ranges from 60 to 70 years old, randomly assigned into two groups: Study group (A) that consists of 35 patients (18 women \&17 men) who perform Liuzijue exercise, 5 sessions per week, 20 minutes per session. and conventional rehabilitation treatment 3 sessions per week, 45-60 minutes per session, for 12 successive weeks.
Control group (B) that consists of 35 patients (18 women \&17 men) in which patients receive just the conventional exercise program, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks.
During the study, the participants receive study information form, instructions and signed the consent form.
- Being tested
- liuzijue qigong exercises, conventional rehabilitation treatment
- Keywords
- liuzijue qigong, ventilatory function, stroke, elderly
- Medical subject headings
- Sleep Initiation and Maintenance Disorders, Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
liuzijue qigong exercisesOther
Liuzijue qigong exercise for 20 minutes, 5 times per week, for 12 successive weeks.
conventional rehabilitation treatmentOther
conventional rehabilitation exercises, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks.
| Study group | Role | What they receive |
|---|---|---|
| Liuzijue Qigong | Experimental | 35 patients will perform : Liuzijue exercise for 20 minutes, 5 times per week, Beside conventional rehabilitation exercises, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks. Receives: Other: liuzijue qigong exercises; Other: conventional rehabilitation treatment |
| Conventional rehabilitation | Active comparator | 35 patients will do only conventional rehabilitation exercises, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks. Receives: Other: conventional rehabilitation treatment |
What is being measured
The primary outcome is the main question the study is designed to answer.
PFT
Spirometer to measure Forced expiratory volume in 1 second (FEV1), in liters
Measured: 3 MONTHS
PFT
Spirometer to measure Forced vital capacity (FVC), in liters
Measured: 3 months
PFT
Spirometer to measure maximum voluntary ventilation (MVV), in liters per minute
Measured: 3 months
PFT
Spirometer to measure Predicted Forced expiratory volume in 1 second
Measured: 3 months
PFT
Spirometer to measure predicted forced vital capacity
Measured: 3 months
PFT
Spirometer to measure FEV1/ FVC
Measured: 3 MONTHS
Secondary outcomes (4)
aerobic capacity and endurance
The six minute walk test Is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity
Measured: 3 MONTHS
motor function
The simplified FMA ( Fugl-Meyer Assessment ) for the assessment of motor function. The scale has a total score of 100, which is divided into motor function evaluation of the upper and lower limbs, among which the upper limb score is 56 and the lower limb score is 44. Each item has a 3-point rating, and a higher score indicates better motor function. The classification of its dysfunction is as follows: < 50 = severe dyskinesia; 50-84 = significant dyspraxia; 85-95 = moderate dyskinesia; 96-99 = mild dyskinesia; and 100 = normal
Measured: 3 MONTHS
quality of daily life
The MBI ( Modified Barthel Index )to evaluate the quality of daily life. The scale is divided into ten items and evaluated on the basis of patients' functional status. The 10 items are eating, bathing, grooming, dressing, controlling bowel movements, controlling urination, toileting, bed and chair transfer, walking on flat ground, and going up and down stairs. The total score is 100 points. The classification of dysfunction is as follows: 100 points = self-care; 61-99 = mild dysfunction; 41-60 = moderate dysfunction; and ≤ 40 = severe dysfunction. The lower the MBI score, the more independent the patients are and the worse their daily living ability
Measured: 3 MONTHS
sleep quality
The PSQI (Pittsburgh sleep quality index) consists of 19 separate items that collectively create 7 components, resulting in a total global score. A lower score indicates better sleep quality
Measured: 3 MONTHS
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Sep 2025
- Study start25 Aug 2025
- Primary completion1 Jan 2026
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ventilatory FunctionStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Aia Muhammad Ibrahem, Cairo University
- Investigators
- Azza Abdelaziz Abdelhady, Professor of Physical Therapy, Study director, faculty of physical therapy
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07153562
- Sponsor's protocol ID
- 012/005865
- Status last verified
- Mar 2026
- First submitted
- 17 Aug 2025
- Last updated
- 17 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Liuzijue Qigong Exercises on Ventilatory Function in Post Stroke Elderly Patients
- ClinicalTrials.gov ID
- NCT07153562
- Acronym / sponsor ID
- 012/005865
- Keywords
- liuzijue qigong, ventilatory function, stroke, elderly
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 25 Aug 2025 (actual)
- Primary completion
- 1 Jan 2026 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 4 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
to investigate the effect of Liuzijue Qigong exercises on ventilatory function in post stroke elderly patients.
Detailed description
70 post stroke patients their ages ranges from 60 to 70 years old, randomly assigned into two groups: Study group (A) that consists of 35 patients (18 women \&17 men) who perform Liuzijue exercise, 5 sessions per week, 20 minutes per session. and conventional rehabilitation treatment 3 sessions per week, 45-60 minutes per session, for 12 successive weeks.
Control group (B) that consists of 35 patients (18 women \&17 men) in which patients receive just the conventional exercise program, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks.
During the study, the participants receive study information form, instructions and signed the consent form.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Liuzijue Qigong | Experimental | Other: liuzijue qigong exercises, Other: conventional rehabilitation treatment35 patients will perform : Liuzijue exercise for 20 minutes, 5 times per week, Beside conventional rehabilitation exercises, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks. |
| Conventional rehabilitation | Active comparator | Other: conventional rehabilitation treatment35 patients will do only conventional rehabilitation exercises, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks. |
Who may qualify
- Ages
- 60 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Subject people of both sexes (18 women, and 17 men).
- All patients had unilateral stroke.
- Their age ranged from 60 to 80 years old.
- Stroke onset was from 6 to 1 months.
- Medically stable subjects.
Key exclusion criteria (9 listed)
- Patients who experienced or had one or more of the following were excluded from the study:
- Patients with severe acute illness.
- Chronic unstable pulmonary and/or cardiac disease.
- Impaired level of consciousness and evidence of gross cognitive problems.
- Patients undergo chemotherapy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| liuzijue qigong exercisesLiuzijue qigong exercise for 20 minutes, 5 times per week, for 12 successive weeks. | Other | Liuzijue Qigong |
| conventional rehabilitation treatmentconventional rehabilitation exercises, 3 sessions per week, 45-60 minutes per session, for 12 successive weeks. | Other | Conventional rehabilitation, Liuzijue Qigong |
Primary outcome
PFT
Time frame: 3 MONTHS
Spirometer to measure Forced expiratory volume in 1 second (FEV1), in liters
PFT
Time frame: 3 months
Spirometer to measure Forced vital capacity (FVC), in liters
PFT
Time frame: 3 months
Spirometer to measure maximum voluntary ventilation (MVV), in liters per minute
PFT
Time frame: 3 months
Spirometer to measure Predicted Forced expiratory volume in 1 second
PFT
Time frame: 3 months
Spirometer to measure predicted forced vital capacity
PFT
Time frame: 3 MONTHS
Spirometer to measure FEV1/ FVC
4 secondary outcomes
aerobic capacity and endurance
Time frame: 3 MONTHS
motor function
Time frame: 3 MONTHS
quality of daily life
Time frame: 3 MONTHS
sleep quality
Time frame: 3 MONTHS
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Mar 2026.
- Individual participant dataSharing planned: No
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EFFECT OF COMBINED VIRTUAL REALITY-GUIDED BREATHING AND AEROBIC TRAINING ON VENTILATORY FUNCTION IN PATIENTS WITH COPD
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Effects of Tart Cherry and Aronia Extract Supplementation on Selected Physiological Parameters in Endurance-Trained Men
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Azza Abdelaziz Abdelhady, Professor of Physical Therapy study director
faculty of physical therapy
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing liuzijue qigong exercises and conventional rehabilitation treatment in people with Ventilatory Function and Functional Capacity, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
PFT (time frame: 3 MONTHS). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Mar 2026.