Carpal Tunnel SyndromeCTSNCT07166029
Effect of Russian Current on Hand Grip Strength and Functional Outcome After Carpal Tunnel Release
A study testing russian current and selected physical therapy program in people with Carpal Tunnel Syndrome, run by Cairo University at 1 site in Egypt.
Trial summary
this study will be conducted to investigate the effect of Russian current on hand grip strength and functional outcome after carpal tunnel release Read more about this study
- Who is it for?
- Ages 30 to 50 years
- Conditions the study is for
- Carpal Tunnel Syndrome
- What is being tested?
- russian current and selected physical therapy program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Sep 2025to 16 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Fifty-two patients with hand muscles weakness post operative carpal tunnel release ,due to severe carpal tunnel syndrome .
- Patient's age will range from 30 to 50 years.
- Patient's body mass index (BMI) will be less than 30kg/m2.
- Presence of wrist pain associated with hand grip weakness.
Who cannot join
- Patients with any other musculoskeletal or neurological disorders in the hand.
- Patients with a history of fractures and dislocations in the hand and wrist.
- Patients with hand deformities and edematous hands.
- Patients with cervical radiculopathy.
- Carpal tunnel syndrome due to conditions like hypothyroidism, rheumatoid arthritis, immunosuppression
Trial locations and contacts
1 site in 1 country.
About this study
this study will be conducted to investigate the effect of Russian current on hand grip strength and functional outcome after carpal tunnel release
Read the detailed description
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy syndrome of the upper extremities , the estimated prevalence is 4-5% in the general population ,it occurs due to median nerve compression in carpal tunnel and it is ten times more common in women ,the most common symptoms are numbness and tingling in the radial 3-1/2 finger, night pain, and paresthesias. Although it is most commonly idiopathic, other causes include trauma, oral contraceptive use, pregnancy, arthritis, diabetes hypothyroidism, and repetitive wrist movements. It is well known that distal radius fractures and their sequelae can cause CTS, this suggests that anatomic changes in bony structures of wrist may also contribute to the development of CTS.Russian current (RC), a well-known neuromuscular electrical stimulation operating at 2500 Hz, has demonstrated significant strength improvement over traditional exercises due to its high tolerance and low pain provocation.There are studies about efficacy of Transcutaneous electrical nerve stimulation on wrist pain in patients with CTR but there is lack of literature about efficacy of RC on hand grip strength and function after CTR so this stidu will be conducted.
- Conditions
- Carpal Tunnel Syndrome
- Being tested
- russian current, selected physical therapy program
- Keywords
- carpal tunnel syndrome, russian current, hand grip strength
- Medical subject headings
- Carpal Tunnel Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
russian currentOther
russian current will be applied in 50Hz sinusoidal bursts with a duty cycle of 50% (10 s on/10 s off). Russian Stimulation (at 2500Hz or 2.5kHz) has been shown to be effective in increasing muscle strength and torque generation through stimulation of type II muscle fiber. The stimulation will be given for duration of 20 minutes , three tims per week plus selected physical therapy program.
selected physical therapy programOther
Patients will receive selected physical therapy program
| Study group | Role | What they receive |
|---|---|---|
| russian current | Experimental | 26 patients will receive Russian current plus a selected physical therapy program three times a week for four weeks. Receives: Other: russian current; Other: selected physical therapy program |
| Selected physical therapy program | Active comparator | 26 patients will receive selected physical therapy program three times a week for four weeks. Receives: Other: selected physical therapy program |
What is being measured
The primary outcome is the main question the study is designed to answer.
hand grip strength
hand grip strength will be measured by hand held dynamometer.
Measured: up to four weeks
hand function
hand function will be measured by boston carpal tunnel questionnaire.The Boston Carpal Tunnel Questionnaire (BCTQ) is a patient-reported questionnaire used to assess symptoms and functional limitations in people with carpal tunnel syndrome (CTS). It consists of two modules: an 11-item Symptom Severity Scale (SSS) and an 8-item Functional Status Scale (FSS), which are scored independently on a 1-to-5 Likert scale.A mean score between 1 and 5 is generated for both the SSS and FSS, with higher scores indicating more severe symptoms or greater functional limitation.
Measured: up to four weeks
Secondary outcomes (2)
wrist range of motion
goniometer device will be used to assess wrist range of motion
Measured: up to four weeks
pain intensity
pain will be measured by visual analogue scale. Scores are based on self-reported measures of symptoms that are recorded with a single handwritten mark placed at one point along the length of a 10-cm line that represents a continuum between the two ends of the scale-"no pain" on the left end (0 cm) of the scale and the "worst pain" on the right end of the scale (10 cm).
Measured: up to four weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Sep 2025
- Study start15 Sep 2025
- Primary completion16 Feb 2026
- Study completion16 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Carpal Tunnel SyndromeStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- russian current and tradional therapy
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 52 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nawal Sayed Ahmed Ibrahim Ahmed, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07166029
- Sponsor's protocol ID
- P.T.REC/012/005964
- Acronym
- CTS
- Status last verified
- May 2026
- First submitted
- 3 Sep 2025
- Last updated
- 20 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Russian Current on Hand Grip Strength and Functional Outcome After Carpal Tunnel Release
- ClinicalTrials.gov ID
- NCT07166029
- Acronym / sponsor ID
- CTS / P.T.REC/012/005964
- Conditions
- Carpal Tunnel Syndrome
- Keywords
- carpal tunnel syndrome, russian current, hand grip strength
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 52 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 15 Sep 2025 (actual)
- Primary completion
- 16 Feb 2026 (actual)
- Study completion
- 16 Feb 2026 (actual)
- First posted
- 10 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
this study will be conducted to investigate the effect of Russian current on hand grip strength and functional outcome after carpal tunnel release
Detailed description
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy syndrome of the upper extremities , the estimated prevalence is 4-5% in the general population ,it occurs due to median nerve compression in carpal tunnel and it is ten times more common in women ,the most common symptoms are numbness and tingling in the radial 3-1/2 finger, night pain, and paresthesias. Although it is most commonly idiopathic, other causes include trauma, oral contraceptive use, pregnancy, arthritis, diabetes hypothyroidism, and repetitive wrist movements. It is well known that distal radius fractures and their sequelae can cause CTS, this suggests that anatomic changes in bony structures of wrist may also contribute to the development of CTS.Russian current (RC), a well-known neuromuscular electrical stimulation operating at 2500 Hz, has demonstrated significant strength improvement over traditional exercises due to its high tolerance and low pain provocation.There are studies about efficacy of Transcutaneous electrical nerve stimulation on wrist pain in patients with CTR but there is lack of literature about efficacy of RC on hand grip strength and function after CTR so this stidu will be conducted.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- russian current and tradional therapy
| Arm | Type | Receives |
|---|---|---|
| russian current | Experimental | Other: russian current, Other: selected physical therapy program26 patients will receive Russian current plus a selected physical therapy program three times a week for four weeks. |
| Selected physical therapy program | Active comparator | Other: selected physical therapy program26 patients will receive selected physical therapy program three times a week for four weeks. |
Who may qualify
- Ages
- 30 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Fifty-two patients with hand muscles weakness post operative carpal tunnel release ,due to severe carpal tunnel syndrome .
- Patient's age will range from 30 to 50 years.
- Patient's body mass index (BMI) will be less than 30kg/m2.
- Presence of wrist pain associated with hand grip weakness.
Key exclusion criteria (5 listed)
- Patients with any other musculoskeletal or neurological disorders in the hand.
- Patients with a history of fractures and dislocations in the hand and wrist.
- Patients with hand deformities and edematous hands.
- Patients with cervical radiculopathy.
- Carpal tunnel syndrome due to conditions like hypothyroidism, rheumatoid arthritis, immunosuppression
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| russian currentrussian current will be applied in 50Hz sinusoidal bursts with a duty cycle of 50% (10 s on/10 s off). Russian Stimulation (at 2500Hz or 2.5kHz) has been shown to be effective in increasing muscle strength and torque generation through stimulation of type II muscle fiber. The stimulation will be given for duration of 20 minutes , three tims per week plus selected physical therapy program. | Other | russian current |
| selected physical therapy programPatients will receive selected physical therapy program | Other | Selected physical therapy program, russian current |
Primary outcome
hand grip strength
Time frame: up to four weeks
hand grip strength will be measured by hand held dynamometer.
hand function
Time frame: up to four weeks
hand function will be measured by boston carpal tunnel questionnaire.The Boston Carpal Tunnel Questionnaire (BCTQ) is a patient-reported questionnaire used to assess symptoms and functional limitations in people with carpal tunnel syndrome (CTS). It consists of two modules: an 11-item Symptom Severity Scale (SSS) and an 8-item Functional Status Scale (FSS), which are scored independently on a 1-to-5 Likert scale.A mean score between 1 and 5 is generated for both the SSS and FSS, with higher scores indicating more severe symptoms or greater functional limitation.
2 secondary outcomes
wrist range of motion
Time frame: up to four weeks
pain intensity
Time frame: up to four weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 May 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing russian current and selected physical therapy program in people with Carpal Tunnel Syndrome, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
hand grip strength (time frame: up to four weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 May 2026.