DynapeniaNCT07180485
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
A study testing whole body vibration training in people with Dynapenia and Abdominal Obesity, run by Dalin Tzu Chi General Hospital.
Trial summary
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life. Read more about this study
- Who is it for?
- Ages 65 to 100 years
- Conditions the study is for
- Dynapenia, Abdominal Obesity
- What is being tested?
- whole body vibration training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 120 participants
- Where
- No sites listed yet
- Study dates
- 1 Oct 2025to 1 Oct 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 100 years
- All sexes
- No healthy volunteers
- Older adult
Who may be able to join
- Outpatients aged 65 years or older
- Diagnosed with dynapenic abdominal obesity
- Able to understand and follow simple instructions
- Able to communicate clearly and express their own will
- Willing to sign the informed consent form
Who cannot join
- Inability to communicate in Mandarin or Taiwanese, resulting in inability to participate in research activities
- Severe visual or hearing impairment that hinders study participation
- Presence of cognitive impairment, musculoskeletal or severe osteoporosis-related conditions
- Refusal to sign the informed consent form
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life. While some benefits have been observed in the elderly population, there remains a research gap concerning its effectiveness in older adults with dynapenic abdominal obesity. Therefore, the findings of this study will provide new evidence for health interventions targeting this specific group.
This research targets outpatients aged 65 and above who meet the criteria for dynapenic abdominal obesity. It aims to evaluate the effects of WBVT on brain activity, osteoporosis, quality of life, and biological markers. The study period is from February 1, 2025, to January 31, 2027, with a planned sample size of 120 participants, equally divided into an experimental group and a control group (60 participants each).
Read the detailed description
The purpose of this study is to investigate the effects of whole body vibration training on older adults with dynapenic abdominal obesity in the following areas:
Brain activity: Changes in serum levels of brain-derived neurotrophic factor (BDNF).
Bone mineral density: Measured using dual-energy X-ray absorptiometry (DXA).
Quality of life: Assessed through questionnaires covering improvements in physical health, mental well-being, and social functioning.
Biomarkers: Changes in levels of total cholesterol, high- and low-density lipoprotein cholesterol, C-reactive protein (CRP), and glycated hemoglobin (HbA1c).
- Conditions
- Dynapenia, Abdominal Obesity
- Being tested
- whole body vibration training, control group
- Keywords
- whole-body vibration training, brain activity, bone mineral density, quality of life, biomarkers
- Medical subject headings
- Obesity, Abdominal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
whole body vibration trainingBehavioural
whole body vibration training and health education booklet
control groupBehavioural
health education booklet
| Study group | Role | What they receive |
|---|---|---|
| whole body vibration training group | Experimental | Participants in the experimental group underwent whole-body vibration (WBV) training three times per week for a total duration of 24 weeks. During each session, participants stood barefoot on a vibration platform, maintaining a static squat position with knees bent at 30 degrees and feet shoulder-width apart. The training protocol gradually increased in duration, number of sets, and total exercise time from an initial 10 minutes to 30 minutes over the 24-week period. The vibration frequency was progressively raised from 20 Hz to 40 Hz, with a constant amplitude of 2 mm. Each 10-minute session included a 1-minute rest interval. Additionally, all participants were provided with the "Move for Health" handbook issued by the Health Promotion Administration, Ministry of Health and Welfare, Taiwan, as part of health education guidance. Post-intervention data collection was conducted at weeks 18 and 25 following the 24-week intervention program. Receives: Behavioral: whole body vibration training |
| control group | Placebo comparator | The control group received the "Move for Health" handbook issued by the Health Promotion Administration, Ministry of Health and Welfare, Taiwan, and participated in 30-minute health education sessions over a 24-week period. The educational content included exercise-related information, an introduction to dynapenic abdominal obesity (DAO), associated risk factors, and potential health consequences. Post-intervention data collection was conducted at weeks 18 and 25 following the 24-week intervention program. Receives: Behavioral: control group |
What is being measured
The primary outcome is the main question the study is designed to answer.
blood tests
Total Cholesterol (TC) Time Frame: Baseline, 3 months, 6 months；Description: Serum total cholesterol level measured in mg/dL. Reference value: < 200 mg/dL.
Triglycerides (TG) Time Frame: Baseline, 3 months, 6 months；Description: Serum triglyceride level measured in mg/dL. Reference value: < 150 mg/dL.
Low-Density Lipoprotein Cholesterol (LDL-C) Time Frame: Baseline, 3 months, 6 months；Description: Serum LDL cholesterol measured in mg/dL. Reference value: < 130 mg/dL.
High-Density Lipoprotein Cholesterol (HDL-C)Time Frame: Baseline, 3 months, 6 months；Description: Serum HDL cholesterol measured in mg/dL. Reference values: > 40 mg/dL for men, > 50 mg/dL for women.
C-Reactive Protein (CRP)Time Frame: Baseline, 3months, 6 months；Description: Quantitative serum CRP level measured in mg/dL. Normal reference value: 0.3 mg/dL.
Glycated Hemoglobin (HbA1c)Time Frame: Baseline, 3 months, 6 months；Description: HbA1c percentage measured in blood. Normal Brain-Derived Neurotroph in pg/mL using
Measured: 24 weeks
dual-energy X-ray absorptiometry(DXA)
This study employed dual-energy X-ray absorptiometry (DXA), a widely used and clinically safe method for assessing bone health. The DXA system (brand referenced in previous publications) operates by emitting a low-radiation dose (±10 μSv) X-ray beam to measure the extent of X-ray penetration through body tissues. Based on the absorption data, the device calculates bone mineral density (BMD). Since bones absorb more X-rays and have high penetrability, while fat absorbs less and has low penetrability, DXA effectively differentiates between tissue types. DXA results are typically interpreted using T-scores for BMD. A T-score ≥ -1.0 indicates normal bone density and good skeletal health. A T-score between -2.5 and -1.0 suggests low bone mass (osteopenia), indicating a decreased BMD but not yet at the threshold for osteoporosis. A T-score ≤ -2.5 defines osteoporosis, indicating significantly reduced BMD and a higher risk of fractures. Severe osteoporosis is diagnosed when a T-score ≤ -2.5.
Measured: 8 months
quality of life questionnaire
The Taiwan version of the World Health Organization Quality of Life questionnaire is a shortened version derived from the original 100-item WHOQOL-100 developed by the World Health Organization. Exploratory and confirmatory factor analyses of the questionnaire support a four-domain model consisting of physical health, psychological well-being, social relationships, and environment. The internal consistency (Cronbach's α) of these four domains ranges from 0.70 to 0.77. The questionnaire includes 28 items: one item for overall quality of life, one for general health, seven for physical health, six for psychological well-being, three for social relationships, and eight for environmental factors. The scale uses a 5-point Likert format based on frequency, intensity, capability, and evaluation. Higher scores indicate better quality of life.
Measured: 24 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Sep 2025
- Study start1 Oct 2025 (estimated)
- Primary completion1 Oct 2027 (estimated)
- Study completion1 Oct 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (93)Papers the sponsor has linked to this study.
- Other trials for DynapeniaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Dalin Tzu Chi General Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Chang Shu Fang, professor, Study chair, National Taipei University of Nursing and Health Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07180485
- Sponsor's protocol ID
- B11401015
- Other IDs
- DTCRD113-E-14
- Status last verified
- May 2025
- First submitted
- 21 May 2025
- Last updated
- 18 Sep 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: can sharing topics and research protocol
Publications
Zago M, Capodaglio P, Ferrario C, Tarabini M, Galli M. Whole-body vibration training in obese subjects: A systematic review. PLoS One. 2018 Sep 5;13(9):e0202866. doi: 10.1371/journal.pone.0202866. eCollection 2018.
PubMed 30183742Zhang L, Liu S, Wang W, Sun M, Tian H, Wei L, Wu Y. Dynapenic abdominal obesity and the effect on long-term gait speed and falls in older adults. Clin Nutr. 2022 Jan;41(1):91-96. doi: 10.1016/j.clnu.2021.11.011. Epub 2021 Nov 15.
PubMed 34864458Zhang J, Wang R, Zheng Y, Xu J, Wu Y, Wang X. Effect of Whole-Body Vibration Training on Muscle Activation for Individuals with Knee Osteoarthritis. Biomed Res Int. 2021 Mar 26;2021:6671390. doi: 10.1155/2021/6671390. eCollection 2021.
PubMed 33855078Yao G, Chung CW, Yu CF, Wang JD. Development and verification of validity and reliability of the WHOQOL-BREF Taiwan version. J Formos Med Assoc. 2002 May;101(5):342-51.
PubMed 12101852Wang X, Jiang J, Hu W, Hu Y, Qin LQ, Hao Y, Dong JY. Dynapenic Abdominal Obesity and Risk of Heart Disease among Middle-Aged and Older Adults: A Prospective Cohort Study. J Nutr Health Aging. 2023;27(9):752-758. doi: 10.1007/s12603-023-1975-0.
PubMed 37754215Wolf D, Ayon-Olivas M, Sendtner M. BDNF-Regulated Modulation of Striatal Circuits and Implications for Parkinson's Disease and Dystonia. Biomedicines. 2024 Aug 5;12(8):1761. doi: 10.3390/biomedicines12081761.
PubMed 39200225Wang W, Wang S, Lin W, Li X, Andersen LL, Wang Y. Efficacy of whole body vibration therapy on pain and functional ability in people with non-specific low back pain: a systematic review. BMC Complement Med Ther. 2020 May 27;20(1):158. doi: 10.1186/s12906-020-02948-x.
PubMed 32460819Wu S, Ning HT, Xiao SM, Hu MY, Wu XY, Deng HW, Feng H. Effects of vibration therapy on muscle mass, muscle strength and physical function in older adults with sarcopenia: a systematic review and meta-analysis. Eur Rev Aging Phys Act. 2020 Sep 17;17:14. doi: 10.1186/s11556-020-00247-5. eCollection 2020.
PubMed 32963629Wang Z, Zhang X, Sun M. The application of whole-body vibration training in knee osteoarthritis. Joint Bone Spine. 2022 Mar;89(2):105276. doi: 10.1016/j.jbspin.2021.105276. Epub 2021 Sep 15.
PubMed 34536625Wen J, Leng L, Hu M, Hou X, Huang J. Effects of whole-body vibration training on cognitive function: A systematic review. Front Hum Neurosci. 2023 Feb 9;17:854515. doi: 10.3389/fnhum.2023.854515. eCollection 2023.
PubMed 36845880Uchida S, Kamiya K, Hamazaki N, Nozaki K, Ichikawa T, Nakamura T, Yamashita M, Maekawa E, Reed JL, Yamaoka-Tojo M, Matsunaga A, Ako J. Prognostic utility of dynapenia in patients with cardiovascular disease. Clin Nutr. 2021 Apr;40(4):2210-2218. doi: 10.1016/j.clnu.2020.09.050. Epub 2020 Oct 13.
PubMed 33873266Torres-Costoso A, Lopez-Munoz P, Martinez-Vizcaino V, Alvarez-Bueno C, Cavero-Redondo I. Association Between Muscular Strength and Bone Health from Children to Young Adults: A Systematic Review and Meta-analysis. Sports Med. 2020 Jun;50(6):1163-1190. doi: 10.1007/s40279-020-01267-y.
PubMed 32060751Tuttle CSL, Thang LAN, Maier AB. Markers of inflammation and their association with muscle strength and mass: A systematic review and meta-analysis. Ageing Res Rev. 2020 Dec;64:101185. doi: 10.1016/j.arr.2020.101185. Epub 2020 Sep 26.
PubMed 32992047Tan TC, Guo YY, Ho DJ, Sanwari NAB, Quek PH, Tan RS, Yap FS, Yang M, Yeung MT. Reference Values, Determinants and Regression Equation for the Timed-Up and Go Test (TUG) in Healthy Asian Population Aged 21 to 85 Years. Int J Environ Res Public Health. 2023 May 3;20(9):5712. doi: 10.3390/ijerph20095712.
PubMed 37174230Teixeira IA, Coutinho ESF, Marinho V, Castro-Costa E, Deslandes AC. Prevalence of dynapenia and overlap with disability, depression, and executive dysfunction. Rev Saude Publica. 2023 Aug 4;57:43. doi: 10.11606/s1518-8787.2023057004580. eCollection 2023.
PubMed 37556665
Study at a glance
From the registry record, last updated by the sponsor on 18 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Whole Body Vibration Training in Improving Brain Activity, Bone Mineral Density, Quality of Life, and Biomarkers for the Older People With Dynapenic Abdominal Obesity
- ClinicalTrials.gov ID
- NCT07180485
- Acronym / sponsor ID
- B11401015
- Conditions
- Dynapenia, Abdominal Obesity
- Keywords
- whole-body vibration training, brain activity, bone mineral density, quality of life, biomarkers
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- Dalin Tzu Chi General HospitalUniversity, hospital or other
- Study start
- 1 Oct 2025 (estimated)
- Primary completion
- 1 Oct 2027 (estimated)
- Study completion
- 1 Oct 2027 (estimated)
- First posted
- 18 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life. While some benefits have been observed in the elderly population, there remains a research gap concerning its effectiveness in older adults with dynapenic abdominal obesity. Therefore, the findings of this study will provide new evidence for health interventions targeting this specific group.
This research targets outpatients aged 65 and above who meet the criteria for dynapenic abdominal obesity. It aims to evaluate the effects of WBVT on brain activity, osteoporosis, quality of life, and biological markers. The study period is from February 1, 2025, to January 31, 2027, with a planned sample size of 120 participants, equally divided into an experimental group and a control group (60 participants each).
Detailed description
The purpose of this study is to investigate the effects of whole body vibration training on older adults with dynapenic abdominal obesity in the following areas:
Brain activity: Changes in serum levels of brain-derived neurotrophic factor (BDNF).
Bone mineral density: Measured using dual-energy X-ray absorptiometry (DXA).
Quality of life: Assessed through questionnaires covering improvements in physical health, mental well-being, and social functioning.
Biomarkers: Changes in levels of total cholesterol, high- and low-density lipoprotein cholesterol, C-reactive protein (CRP), and glycated hemoglobin (HbA1c).
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| whole body vibration training group | Experimental | Behavioral: whole body vibration trainingParticipants in the experimental group underwent whole-body vibration (WBV) training three times per week for a total duration of 24 weeks. During each session, participants stood barefoot on a vibration platform, maintaining a static squat position with knees bent at 30 degrees and feet shoulder-width apart. The training protocol gradually increased in duration, number of sets, and total exercise time from an initial 10 minutes to 30 minutes over the 24-week period. The vibration frequency was progressively raised from 20 Hz to 40 Hz, with a constant amplitude of 2 mm. Each 10-minute session included a 1-minute rest interval. Additionally, all participants were provided with the "Move for Health" handbook issued by the Health Promotion Administration, Ministry of Health and Welfare, Taiwan, as part of health education guidance. Post-intervention data collection was conducted at weeks 18 and 25 following the 24-week intervention program. |
| control group | Placebo comparator | Behavioral: control groupThe control group received the "Move for Health" handbook issued by the Health Promotion Administration, Ministry of Health and Welfare, Taiwan, and participated in 30-minute health education sessions over a 24-week period. The educational content included exercise-related information, an introduction to dynapenic abdominal obesity (DAO), associated risk factors, and potential health consequences. Post-intervention data collection was conducted at weeks 18 and 25 following the 24-week intervention program. |
Who may qualify
- Ages
- 65 to 100 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (5 listed)
- Outpatients aged 65 years or older
- Diagnosed with dynapenic abdominal obesity
- Able to understand and follow simple instructions
- Able to communicate clearly and express their own will
- Willing to sign the informed consent form
Key exclusion criteria (4 listed)
- Inability to communicate in Mandarin or Taiwanese, resulting in inability to participate in research activities
- Severe visual or hearing impairment that hinders study participation
- Presence of cognitive impairment, musculoskeletal or severe osteoporosis-related conditions
- Refusal to sign the informed consent form
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| whole body vibration trainingwhole body vibration training and health education booklet | Behavioural | whole body vibration training group |
| control grouphealth education booklet | Behavioural | control group |
Primary outcome
blood tests
Time frame: 24 weeks
Total Cholesterol (TC) Time Frame: Baseline, 3 months, 6 months；Description: Serum total cholesterol level measured in mg/dL. Reference value: < 200 mg/dL. Triglycerides (TG) Time Frame: Baseline, 3 months, 6 months；Description: Serum triglyceride level measured in mg/dL. Reference value: < 150 mg/dL. Low-Density Lipoprotein Cholesterol (LDL-C) Time Frame: Baseline, 3 months, 6 months；Description: Serum LDL cholesterol measured in mg/dL. Reference value: < 130 mg/dL. High-Density Lipoprotein Cholesterol (HDL-C)Time Frame: Baseline, 3 months, 6 months；Description: Serum HDL cholesterol measured in mg/dL. Reference values: > 40 mg/dL for men, > 50 mg/dL for women. C-Reactive Protein (CRP)Time Frame: Baseline, 3months, 6 months；Description: Quantitative serum CRP level measured in mg/dL. Normal reference value: 0.3 mg/dL. Glycated Hemoglobin (HbA1c)Time Frame: Baseline, 3 months, 6 months；Description: HbA1c percentage measured in blood. Normal Brain-Derived Neurotroph in pg/mL using
dual-energy X-ray absorptiometry(DXA)
Time frame: 8 months
This study employed dual-energy X-ray absorptiometry (DXA), a widely used and clinically safe method for assessing bone health. The DXA system (brand referenced in previous publications) operates by emitting a low-radiation dose (±10 μSv) X-ray beam to measure the extent of X-ray penetration through body tissues. Based on the absorption data, the device calculates bone mineral density (BMD). Since bones absorb more X-rays and have high penetrability, while fat absorbs less and has low penetrability, DXA effectively differentiates between tissue types. DXA results are typically interpreted using T-scores for BMD. A T-score ≥ -1.0 indicates normal bone density and good skeletal health. A T-score between -2.5 and -1.0 suggests low bone mass (osteopenia), indicating a decreased BMD but not yet at the threshold for osteoporosis. A T-score ≤ -2.5 defines osteoporosis, indicating significantly reduced BMD and a higher risk of fractures. Severe osteoporosis is diagnosed when a T-score ≤ -2.5.
quality of life questionnaire
Time frame: 24 weeks
The Taiwan version of the World Health Organization Quality of Life questionnaire is a shortened version derived from the original 100-item WHOQOL-100 developed by the World Health Organization. Exploratory and confirmatory factor analyses of the questionnaire support a four-domain model consisting of physical health, psychological well-being, social relationships, and environment. The internal consistency (Cronbach's α) of these four domains ranges from 0.70 to 0.77. The questionnaire includes 28 items: one item for overall quality of life, one for general health, seven for physical health, six for psychological well-being, three for social relationships, and eight for environmental factors. The scale uses a 5-point Likert format based on frequency, intensity, capability, and evaluation. Higher scores indicate better quality of life.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Sep 2025.
- Results publication: PubMed 30183742Zago M, Capodaglio P, Ferrario C, Tarabini M, Galli M. Whole-body vibration training in obese subjects: A systematic review. PLoS One. 2018 Sep 5;13(9):e0202866. doi: 10.1371/journal.pone.0202866. eCollection 2018.
- Results publication: PubMed 34864458Zhang L, Liu S, Wang W, Sun M, Tian H, Wei L, Wu Y. Dynapenic abdominal obesity and the effect on long-term gait speed and falls in older adults. Clin Nutr. 2022 Jan;41(1):91-96. doi: 10.1016/j.clnu.2021.11.011. Epub 2021 Nov 15.
- Results publication: PubMed 33855078Zhang J, Wang R, Zheng Y, Xu J, Wu Y, Wang X. Effect of Whole-Body Vibration Training on Muscle Activation for Individuals with Knee Osteoarthritis. Biomed Res Int. 2021 Mar 26;2021:6671390. doi: 10.1155/2021/6671390. eCollection 2021.
- Results publication: PubMed 12101852Yao G, Chung CW, Yu CF, Wang JD. Development and verification of validity and reliability of the WHOQOL-BREF Taiwan version. J Formos Med Assoc. 2002 May;101(5):342-51.
- Results publication: PubMed 37754215Wang X, Jiang J, Hu W, Hu Y, Qin LQ, Hao Y, Dong JY. Dynapenic Abdominal Obesity and Risk of Heart Disease among Middle-Aged and Older Adults: A Prospective Cohort Study. J Nutr Health Aging. 2023;27(9):752-758. doi: 10.1007/s12603-023-1975-0.
- Results publication: PubMed 39200225Wolf D, Ayon-Olivas M, Sendtner M. BDNF-Regulated Modulation of Striatal Circuits and Implications for Parkinson's Disease and Dystonia. Biomedicines. 2024 Aug 5;12(8):1761. doi: 10.3390/biomedicines12081761.
- Results publication: PubMed 32460819Wang W, Wang S, Lin W, Li X, Andersen LL, Wang Y. Efficacy of whole body vibration therapy on pain and functional ability in people with non-specific low back pain: a systematic review. BMC Complement Med Ther. 2020 May 27;20(1):158. doi: 10.1186/s12906-020-02948-x.
- Results publication: PubMed 32963629Wu S, Ning HT, Xiao SM, Hu MY, Wu XY, Deng HW, Feng H. Effects of vibration therapy on muscle mass, muscle strength and physical function in older adults with sarcopenia: a systematic review and meta-analysis. Eur Rev Aging Phys Act. 2020 Sep 17;17:14. doi: 10.1186/s11556-020-00247-5. eCollection 2020.
- Results publication: PubMed 34536625Wang Z, Zhang X, Sun M. The application of whole-body vibration training in knee osteoarthritis. Joint Bone Spine. 2022 Mar;89(2):105276. doi: 10.1016/j.jbspin.2021.105276. Epub 2021 Sep 15.
- Results publication: PubMed 36845880Wen J, Leng L, Hu M, Hou X, Huang J. Effects of whole-body vibration training on cognitive function: A systematic review. Front Hum Neurosci. 2023 Feb 9;17:854515. doi: 10.3389/fnhum.2023.854515. eCollection 2023.
- Results publication: PubMed 33873266Uchida S, Kamiya K, Hamazaki N, Nozaki K, Ichikawa T, Nakamura T, Yamashita M, Maekawa E, Reed JL, Yamaoka-Tojo M, Matsunaga A, Ako J. Prognostic utility of dynapenia in patients with cardiovascular disease. Clin Nutr. 2021 Apr;40(4):2210-2218. doi: 10.1016/j.clnu.2020.09.050. Epub 2020 Oct 13.
- Results publication: PubMed 32060751Torres-Costoso A, Lopez-Munoz P, Martinez-Vizcaino V, Alvarez-Bueno C, Cavero-Redondo I. Association Between Muscular Strength and Bone Health from Children to Young Adults: A Systematic Review and Meta-analysis. Sports Med. 2020 Jun;50(6):1163-1190. doi: 10.1007/s40279-020-01267-y.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: Yes. can sharing topics and research protocol
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Chang Shu Fang, professor study chair
National Taipei University of Nursing and Health Sciences
Questions about this trial
What is this clinical trial studying?
A study testing whole body vibration training in people with Dynapenia and Abdominal Obesity, run by Dalin Tzu Chi General Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 18 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact SHIH CHUN LIN (+88652648000 ext. 3112, t780927t@yahoo.com.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
blood tests (time frame: 24 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07180485, which also lists 93 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Sep 2025.