Clinical trials: Dynapenia
Sarcopenia, Dysphagia
Comparison of the Swallowing Functions in Sarcopenia and Dynapenia
The purpose of the study to investigate the comparison of the swallowing functions of the sarcopenia and dynapenia in older patients
- Conditions
- Sarcopenia, Dysphagia, Swallowing Disorder
- Trial name
- NCT04960007
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Healthy
Personalised Modeling and Simulation Procedures for the Differential Diagnosis of Dynapenia: a Study on Healthy Volunteers
The ForceLoss study aims to develop personalised modeling and simulation procedures to enable the differential diagnosis for the loss of muscle force, namely dynapenia.
- Trial name
- NCT05091502
- Testing
- Personalised musculoskeletal modeling
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Dynapenia, Postmenopausal Women
Tocotrienols for Skeletal Muscle Health
Sarcopenia, defined as a reduction in muscle mass and strength, is a major health concern for postmenopausal women. Evidence suggests that lowering inflammation levels is an important strategy to help mitigate age-related muscle…
- Trial name
- VitE-muscle (NCT03708354)
- Testing
- DeltaGold® Tocotrienol 70%
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Non-small-cell Lung Cancer, Sarcopenia
Nutritional Assessment of Patients With Non-small Cell Lung Cancer Treated With Osimertinib
Nutritional assessment of patients with non-small cell lung cancer treated with osimertinib. Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer cases and is a leading cause of morbidity and…
- Conditions
- Non-small-cell Lung Cancer, Sarcopenia, Quality of Life
- Trial name
- NUTRI-CPNM (NCT07559526)
- Testing
- Unic group
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
Chronic Kidney Disease (CKD) induces many metabolic troubles especially for the advanced CKD (stage 3b-5) patients and their prevalence and importance grow with the deterioration of the glomerular filtration rate (GFR).
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Fatigue
- Trial name
- PIONEER (NCT04330807)
- Testing
- Handgrip fatigability test, Questionnaires
- Where
- France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
Sarcopenia in Elderly, Dynapenia
Reduction in Resistance Training Volume and Neuromuscular Adaptations in Older Adults
The goal of this clinical trial is to evaluate how reducing resistance training volume affects neuromuscular adaptations in older adults aged 60 to 70 years.
- Trial name
- NCT07046130
- Testing
- Resistance Training
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dynapenia
The Application of an Innovative Reactive Agility Testing System for Assessment in Older Adults With Dynapenia
Before the experiment, the researchers explain the purpose and procedures to the participants. After signing the informed consent form and completing basic personal information, participants perform a 5-minute warm-up.
- Trial name
- NCT07375888
- Testing
- Reactive Agility Testing System
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Dynapenia, Aging
Protein Supplementation and Mixed Power Training on Muscle Function and Functional Capacities in Elderly Men
Investigate the effect of 12 weeks mixed power training (power and functional exercises) combined with a protein supplementation (30g/d) or not (placebo) on physiological characteristics of muscle and functional capacities in…
- Conditions
- Dynapenia, Aging, Physical Impairment
- Trial name
- PROMU (NCT03393650)
- Testing
- Exercise + Protein group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Dynapenia, Obesity
An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition
The purpose of the trial is to assess the effects of combining regular, generous intakes of high quality protein (primarily from dairy and other animal source proteins) with calorie restriction and low-intensity exercise on…
- Trial name
- DDYNAMO (NCT02437643)
- Testing
- Weight Loss, Dairy Protein, Low intensity exercise
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Duke University
Osteoarthritis, Knee
Personalised Modeling and Simulations for the Differential Diagnosis of Dynapenia: Study on Patients With Osteoarthritis
The ForceLoss study aims to develop personalised modeling and simulation procedures to enable the differential diagnosis for the loss of muscle force, namely dynapenia.
- Trial name
- ForceLoss II (NCT05795348)
- Testing
- Personalised Musculoskeletal Modeling
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Dynapenia, Muscle Weakness
Effect Of The Presence Of Dynapenia On Posture, Spine Muscle Elasticity, Strength And Endurance In Young Adults
The aim of the present study was to determine the effect of dynapenia on posture, spinal muscle elasticity, strength and endurance in young adults.
- Conditions
- Dynapenia, Muscle Weakness, Sarcopenia
- Trial name
- NCT06621875
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aynur Ayazzade
Muscular Atrophy
Two Weeks of Reduced Activity and Skeletal Muscle Health in Older Men
Muscle size declines at around 0.5-1% per year after 50 years of age, with muscle strength declining up to twice as fast as muscle size.
- Trial name
- NCT02495727
- Testing
- Step-reduction, Pre-training, Exercise snacking
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Bath
Geriatric Individuals
Investigation of Inspiratory Muscle Strength and Cardiorespiratory Fitness in Sarcopenic Individuals
The aim of our study is to examine the effects of sarcopenia and dynapenia on inspiratory muscle strength and cardiorespiratory fitness in geriatric individuals.
- Trial name
- NCT06398704
- Testing
- Standart of care
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Hacettepe University
Muscle Weakness, Dynapenia
Mirror Neurons in Older Participants
A critical problem facing aging adults is muscle weakness. Whereas scientists have traditionally attributed the loss of muscle strength with aging to muscle atrophy, emerging evidence suggests that impairments in the…
- Conditions
- Muscle Weakness, Dynapenia, Sarcopenia
- Trial name
- MNOP (NCT03946709)
- Testing
- Action Observation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Multiple Sclerosis, Sarcopenia
Investigation of the Prevalence of Sarcopenia and Dynapenia According to Disease Stage in Patients With Multiple Sclerosis and Evaluation of the Relationship Between Sarcopenia Severity and Clinical and Functional Parameters
This cross-sectional observational study aims to determine the prevalence of sarcopenia and dynapenia across disability stages in patients with multiple sclerosis (MS) and investigate their associations with clinical and…
- Conditions
- Multiple Sclerosis, Sarcopenia, Dynapenia
- Trial name
- MS-Sarcopenia (NCT07842731)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Frail Elderly Syndrome
Protocols and Guidelines for the Use of Digital Twins in Frail Older People
The Proto-Aging study aims to define experimental protocols and guidelines to enable the development of musculoskeletal models (digital twins) of elderly people, with the ultimate goal to comprehensively characterize frail elders…
- Trial name
- Proto-Aging (NCT05854316)
- Testing
- Comprehensive Biomechanical assessment
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Sarcopenia, Physical Fitness
Swedish Physical Activity and Fitness Longitudinal Study
Aging means loss of strength, which can affect the ability to lead an active life and be independent. Physical activity can counteract the loss of strength to some extent, but individual differences are large and the mechanisms…
- Conditions
- Sarcopenia, Physical Fitness, Muscle Strength, Dynapenia
- Trial name
- SPAF (NCT06496204)
- Where
- Sweden
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Functional Disability, Dynapenia
Exercise Based on Proprioceptive Neuromuscular Facilitation in Older Individuals
The goal of this clinical trial was to determine whether an intervention using resisted sit-to-stand and walking exercises with Proprioceptive Neuromuscular Facilitation (PNF) techniques improved gait and sit-to-stand in older…
- Conditions
- Functional Disability, Dynapenia, Sarcopenia in Elderly
- Trial name
- NCT06690944
- Testing
- Proprioceptive Neuromuscular Facilitation, Physical exercise without proprioceptive neuromuscular facilitation control group
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Dynapenia
Blood Flow Restriction Parameters and Lower Limb Function in Older Adults With Dynapenia
The objective of the first year is to collect limb occlusion pressure (LOP) measurements in older adults with varying levels of muscle health, which will serve as foundational data for subsequent investigations on blood flow…
- Trial name
- NCT07534150
- Testing
- Blood Flow Restriction, Conventional Resistance Training
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Aging
The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders
The UNCODE Study seeks to better identify the neurological causes of muscle weakness associated with advancing age. The main study consists of 4 laboratory-based testing sessions that involve testing muscle strength and physical…
- Trial name
- NCT02505529
- Testing
- Resistance Exercise Training, Mental Imagery
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ohio University