Dynamic Knee ValgusDKV-EXNCT07192796
Effects of Pilates and Neuromuscular Exercises on Postural Control in Dynamic Knee Valgus
A study testing Pilates Exercise Program and Neuromuscular Exercise Program in people with Dynamic Knee Valgus and Knee Injuries, run by Şebnem Nur Alkan at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled trial aims to investigate the effects of neuromuscular and Pilates exercise programs compared with a control group in young adults with dynamic knee valgus (DKV). Thirty-six participants were randomly assigned to neuromuscular, Pilates, or control groups. Read more about this study
- Who is it for?
- Ages 18 to 24 yearsHealthy volunteers can take part
- Conditions the study is for
- Dynamic Knee Valgus, Knee Injuries, Postural Control Deficit
- What is being tested?
- Pilates Exercise Program and Neuromuscular Exercise Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jun 2024to 30 Aug 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 24 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- having asymptomatic dynamic knee valgus
- being between 18 and 24 years of age
- having no medical history, a body mass index (BMI) between 18 and 24
- no history of orthopedic, neurological, vascular, systemic, or rheumatic diseases
- no complaints of pain in any part of the body during physical activities
- the ability to communicate in Turkish (both written and verbal)
Who cannot join
- individuals with hip anteversion or retroversion or other postural disorders affecting knee kinematics, those unable to perform the exercises as demonstrated, those experiencing pain during exercises (VAS >5)
- individuals with a history of orthopedic surgery, those with strength deficits between extremities
- the presence of cognitive or psychological disorders that could hinder cooperation
- pregnancy or suspected pregnancy
- sleep disorders, regular medication use, intake of painkillers, sedatives, or psychiatric drugs within the last 24 hours
- history of chronic systemic, rheumatologic, neurological, or vascular diseases
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparative Effects of Pilates and Neuromuscular Exercises on Postural Control in Dynamic Knee Valgus
This randomized controlled trial aims to investigate the effects of neuromuscular and Pilates exercise programs compared with a control group in young adults with dynamic knee valgus (DKV). Thirty-six participants were randomly assigned to neuromuscular, Pilates, or control groups. The intervention groups completed a supervised exercise program three times per week for six weeks (18 sessions).
The primary outcome is the frontal plane projection angle (FPPA) during single-leg tasks. Secondary outcomes include muscle strength, balance, and vertical jump performance.
Read the detailed description
This prospective, single-blind randomized controlled trial was designed to evaluate the comparative effects of Pilates and neuromuscular exercise training on lower extremity alignment and postural control in young adults with dynamic knee valgus (DKV). Ethical approval was obtained from the Istanbul Atlas University Non-Interventional Scientific Research Ethics Committee (Approval No: E-22686390-050.99-41964, 03/05/2024).
A total of 45 participants aged 18-24 years, all right-leg dominant, were initially enrolled and randomized into three groups: Pilates, neuromuscular exercise, and control (15 in each group). Randomization was performed using computerized allocation. Due to dropouts, 36 participants (12 per group) completed the study between June and August 2024.
The interventions consisted of a 6-week supervised program (18 sessions, 3 times per week). Both Pilates and neuromuscular protocols were progressive in intensity, incorporating resistance bands, core stabilization, and functional balance exercises. The control group did not receive any intervention but underwent the same baseline and post-intervention assessments.
The primary outcome was the frontal plane projection angle (FPPA) during single-leg squat and single-leg drop jump tasks, measured using 2D video analysis.
The secondary outcomes included:
Isometric strength of the gluteus medius and rectus femoris measured with a handheld dynamometer,
Balance performance assessed separately by the Biodex Postural Stability Test (overall, anterior-posterior, and medial-lateral stability indices) and the Limits of Stability Test,
Functional performance assessed by the OptoJump system, including vertical jump height, vertical jump power, and reactive strength index.
All assessments were conducted at baseline and after 6 weeks by the same physiotherapist to ensure intra-rater reliability.
- Conditions
- Dynamic Knee Valgus, Knee Injuries, Postural Control Deficit
- Being tested
- Pilates Exercise Program, Neuromuscular Exercise Program
- Keywords
- Dynamic knee valgus, Neuromuscular exercise, Pilates, Frontal plane projection angle, Postural control
- Medical subject headings
- Knee Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pilates Exercise ProgramBehavioural
A 6-week supervised Pilates exercise program, with 18 sessions. Exercises focused on core stabilization, posture, and lower limb alignment using mat-based and resistance band movements.
Neuromuscular Exercise ProgramBehavioural
A 6-week supervised neuromuscular training program, 18 sessions . Training emphasized balance, proprioception, dynamic stability, and strengthening of lower extremity muscles.
| Study group | Role | What they receive |
|---|---|---|
| Pilates Exercise Group | Experimental | Participants in this group completed a 6-week supervised Pilates exercise program, with 18 sessions. The program included mat-based and resistance band exercises focusing on core stabilization and postural alignment. Receives: Behavioral: Pilates Exercise Program |
| Neuromuscular Exercise Group | Experimental | Participants in this group performed a progressive neuromuscular training program for 6 weeks, with 18 supervised sessions. The program emphasized balance, proprioception, dynamic stability, and strengthening of lower extremity muscles. Receives: Behavioral: Neuromuscular Exercise Program |
| Control Group | No intervention | Participants in this group did not receive any exercise intervention during the 6-week period. They underwent the same baseline and post-intervention assessments as the experimental groups but continued with their usual daily activities. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Frontal Plane Projection Angle (FPPA)
Participants performed a single-leg vertical drop jump from a 20 cm platform with the dominant leg while keeping their hands on the waist. Knee valgus angle at landing was recorded using 2D video analysis with a camera placed 3 m in front at a height of 45 cm.
Measured: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)
Secondary outcomes (2)
Isometric Strength of Gluteus Medius
Isometric strength of the gluteus medius muscle was measured using the PowerTrack-II handheld dynamometer in a standardized side-lying position.
Measured: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)
Isometric Strength of Rectus Femoris
Isometric strength of the rectus femoris muscle was measured using the PowerTrack-II handheld dynamometer in a standardized seated position with 90° knee flexion.
Measured: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Sep 2025
- Study start1 Jun 2024
- Primary completion20 Aug 2024
- Study completion30 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dynamic Knee ValgusStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants were randomized into three parallel groups: a Pilates exercise group, a neuromuscular exercise group, and a control group. Interventions were delivered over 6 weeks (18 sessions).
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Şebnem Nur Alkan
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Şebnem Nur Alkan, Atlas University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07192796
- Sponsor's protocol ID
- E-22686390-050.99-41964
- Acronym
- DKV-EX
- Status last verified
- Sep 2025
- First submitted
- 3 Sep 2025
- Last updated
- 25 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Pilates and Neuromuscular Exercises on Postural Control in Dynamic Knee Valgus
- ClinicalTrials.gov ID
- NCT07192796
- Acronym / sponsor ID
- DKV-EX / E-22686390-050.99-41964
- Conditions
- Dynamic Knee Valgus, Knee Injuries, Postural Control Deficit
- Keywords
- Dynamic knee valgus, Neuromuscular exercise, Pilates, Frontal plane projection angle, Postural control
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Şebnem Nur AlkanUniversity, hospital or other
- Study start
- 1 Jun 2024 (actual)
- Primary completion
- 20 Aug 2024 (actual)
- Study completion
- 30 Aug 2024 (actual)
- First posted
- 25 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial aims to investigate the effects of neuromuscular and Pilates exercise programs compared with a control group in young adults with dynamic knee valgus (DKV). Thirty-six participants were randomly assigned to neuromuscular, Pilates, or control groups. The intervention groups completed a supervised exercise program three times per week for six weeks (18 sessions).
The primary outcome is the frontal plane projection angle (FPPA) during single-leg tasks. Secondary outcomes include muscle strength, balance, and vertical jump performance.
Detailed description
This prospective, single-blind randomized controlled trial was designed to evaluate the comparative effects of Pilates and neuromuscular exercise training on lower extremity alignment and postural control in young adults with dynamic knee valgus (DKV). Ethical approval was obtained from the Istanbul Atlas University Non-Interventional Scientific Research Ethics Committee (Approval No: E-22686390-050.99-41964, 03/05/2024).
A total of 45 participants aged 18-24 years, all right-leg dominant, were initially enrolled and randomized into three groups: Pilates, neuromuscular exercise, and control (15 in each group). Randomization was performed using computerized allocation. Due to dropouts, 36 participants (12 per group) completed the study between June and August 2024.
The interventions consisted of a 6-week supervised program (18 sessions, 3 times per week). Both Pilates and neuromuscular protocols were progressive in intensity, incorporating resistance bands, core stabilization, and functional balance exercises. The control group did not receive any intervention but underwent the same baseline and post-intervention assessments.
The primary outcome was the frontal plane projection angle (FPPA) during single-leg squat and single-leg drop jump tasks, measured using 2D video analysis.
The secondary outcomes included:
Isometric strength of the gluteus medius and rectus femoris measured with a handheld dynamometer,
Balance performance assessed separately by the Biodex Postural Stability Test (overall, anterior-posterior, and medial-lateral stability indices) and the Limits of Stability Test,
Functional performance assessed by the OptoJump system, including vertical jump height, vertical jump power, and reactive strength index.
All assessments were conducted at baseline and after 6 weeks by the same physiotherapist to ensure intra-rater reliability.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
- Model description
- Participants were randomized into three parallel groups: a Pilates exercise group, a neuromuscular exercise group, and a control group. Interventions were delivered over 6 weeks (18 sessions).
| Arm | Type | Receives |
|---|---|---|
| Pilates Exercise Group | Experimental | Behavioral: Pilates Exercise ProgramParticipants in this group completed a 6-week supervised Pilates exercise program, with 18 sessions. The program included mat-based and resistance band exercises focusing on core stabilization and postural alignment. |
| Neuromuscular Exercise Group | Experimental | Behavioral: Neuromuscular Exercise ProgramParticipants in this group performed a progressive neuromuscular training program for 6 weeks, with 18 supervised sessions. The program emphasized balance, proprioception, dynamic stability, and strengthening of lower extremity muscles. |
| Control Group | No intervention | –Participants in this group did not receive any exercise intervention during the 6-week period. They underwent the same baseline and post-intervention assessments as the experimental groups but continued with their usual daily activities. |
Who may qualify
- Ages
- 18 to 24 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- having asymptomatic dynamic knee valgus
- being between 18 and 24 years of age
- having no medical history, a body mass index (BMI) between 18 and 24
- no history of orthopedic, neurological, vascular, systemic, or rheumatic diseases
- no complaints of pain in any part of the body during physical activities
Key exclusion criteria (6 listed)
- individuals with hip anteversion or retroversion or other postural disorders affecting knee kinematics, those unable to perform the exercises as demonstrated, those experiencing pain during exercises (VAS >5)
- individuals with a history of orthopedic surgery, those with strength deficits between extremities
- the presence of cognitive or psychological disorders that could hinder cooperation
- pregnancy or suspected pregnancy
- sleep disorders, regular medication use, intake of painkillers, sedatives, or psychiatric drugs within the last 24 hours
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pilates Exercise ProgramA 6-week supervised Pilates exercise program, with 18 sessions. Exercises focused on core stabilization, posture, and lower limb alignment using mat-based and resistance band movements. | Behavioural | Pilates Exercise Group |
| Neuromuscular Exercise ProgramA 6-week supervised neuromuscular training program, 18 sessions . Training emphasized balance, proprioception, dynamic stability, and strengthening of lower extremity muscles. | Behavioural | Neuromuscular Exercise Group |
Primary outcome
Frontal Plane Projection Angle (FPPA)
Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)
Participants performed a single-leg vertical drop jump from a 20 cm platform with the dominant leg while keeping their hands on the waist. Knee valgus angle at landing was recorded using 2D video analysis with a camera placed 3 m in front at a height of 45 cm.
2 secondary outcomes
Isometric Strength of Gluteus Medius
Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)
Isometric Strength of Rectus Femoris
Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Sep 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pilates Exercise Program and Neuromuscular Exercise Program in people with Dynamic Knee Valgus and Knee Injuries, run by Şebnem Nur Alkan at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Frontal Plane Projection Angle (FPPA) (time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Sep 2025.