Acute Coronary SyndromesNCT07203924
Prognostic Importance of Physical Activity in Geriatric Patients With Acute Coronary Syndrome
An observational study of Acute Coronary Syndromes and Geriatric Patients, run by Balikesir University at 1 site in Turkey (Türkiye).
Trial summary
This observational study evaluated the relationship between physical activity level and prognosis in geriatric patients admitted to the emergency department with acute coronary syndrome (ACS). A total of 207 patients aged 65 years and older were included. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Acute Coronary Syndromes, Geriatric Patients, Physical Activity Levels
- How many people
- 207 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 4 Dec 2024to 11 Sep 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: The study population consisted of 207 geriatric patients aged 65 years and older who were admitted to the emergency department with a diagnosis of acute coronary syndrome (ACS)
Who may be able to join
- Age ≥ 65 years
- Admission to the emergency department with a diagnosis of acute coronary syndrome (ACS)
- Ability to complete the International Physical Activity Questionnaire-Short Form (IPAQ-SF)
Who cannot join
- Age < 65 years
- Patients without ACS diagnosis
- Patients unable to complete the IPAQ-SF questionnaire (e.g., due to severe cognitive impairment or communication problems)
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Balıkesir University Faculty of Sport Sciences / Department of Coaching Education
Balıkesir, Balıkesir, 10145
About this study
Official title: Prognostic Importance of Physical Activity Level in Geriatric Patients With Acute Coronary Syndrome
This observational study evaluated the relationship between physical activity level and prognosis in geriatric patients admitted to the emergency department with acute coronary syndrome (ACS). A total of 207 patients aged 65 years and older were included. Physical activity level was assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF) and compared with clinical outcomes and risk scores (TIMI, HEART, SVEAT). Results showed that patients with higher physical activity levels had lower rates of major adverse cardiac events (MACE) and mortality, as well as lower risk scores. The findings suggest that physical activity is an independent protective factor that improves prognosis in older patients with ACS.
Read the detailed description
Acute coronary syndrome (ACS) in elderly patients is associated with high morbidity and mortality, and identifying prognostic factors is clinically important. Physical activity is known to have protective cardiovascular effects, but its prognostic role in geriatric ACS patients remains unclear.
This observational study will include 207 patients aged 65 years and older who present to the emergency department with ACS. Physical activity levels will be measured using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). Activity scores will then be compared with clinical outcomes, including major adverse cardiac events (MACE), mortality, and risk stratification scores (TIMI, HEART, SVEAT).
- Keywords
- Acute Coronary Syndrome, TIMI, HEART, SVEAT, Physical Activity
- Medical subject headings
- Acute Coronary Syndrome, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Geriatric ACS Patients | This cohort consists of 207 patients aged 65 years and older who presented to the emergency department with acute coronary syndrome (ACS). No intervention was performed. Physical activity levels were assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), and outcomes were compared with major adverse cardiac events (MACE), mortality, and risk scores (TIMI, HEART, SVEAT). |
What is being measured
The primary outcome is the main question the study is designed to answer.
Major Adverse Cardiac Events (MACE)
Occurrence of major adverse cardiac events (MACE) including STEMI, NSTEMI, unstable angina, or cardiovascular mortality.
Measured: Within 30 days after emergency department admission
Secondary outcomes (5)
Physical Activity Score (IPAQ-SF)
Physical activity level measured using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Score range: 0 to 1920 MET-minutes/week. Higher scores indicate greater levels of physical activity.
Measured: At baseline (hospital admission, emergency department evaluation)
TIMI Risk Score
Thrombolysis in Myocardial Infarction (TIMI) Risk Score. Risk stratification assessed using the TIMI Risk Score, which is based on clinical history, electrocardiogram findings, troponin levels, and cardiovascular risk factors. Score range: 0 to 7. Higher scores indicate greater risk and worse prognosis.
Measured: At baseline (emergency department evaluation)
HEART Risk Score
HEART Risk Score (History, Electrocardiogram, Age, Risk factors, Troponin). Risk stratification assessed using the HEART Risk Score, which is based on patient history, electrocardiogram findings, age, cardiovascular risk factors, and troponin levels. Score range: 0 to 10. Higher scores indicate increased risk of major adverse cardiac events (worse prognosis).
Measured: At baseline (emergency department evaluation)
SVEAT Risk Score
SVEAT Risk Score (Symptoms, Vascular disease, Electrocardiogram, Age, Troponin). Risk stratification assessed using the SVEAT Risk Score, based on symptoms, history of vascular disease, electrocardiogram findings, age, and troponin levels. Score range: 0 to 10. Higher scores indicate increased cardiovascular risk and worse prognosis.
Measured: At baseline (emergency department evaluation)
All-cause Mortality
Death from any cause among study participants after acute coronary syndrome.
Measured: Within 30 days after admission
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Oct 2025
- Study start4 Dec 2024
- Primary completion1 Sep 2025
- Study completion11 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Acute Coronary SyndromesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 207 participants (actual)
Sponsor and investigators
- Lead sponsor
- Balikesir University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Özkan Işık, Balikesir University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07203924
- Sponsor's protocol ID
- 2024/192 (BU Ethics No)
- Status last verified
- Oct 2025
- First submitted
- 12 Sep 2025
- Last updated
- 6 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared because the study is retrospective and based on hospital records, and data sharing is restricted due to patient privacy and ethical considerations.
Study at a glance
From the registry record, last updated by the sponsor on 6 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prognostic Importance of Physical Activity Level in Geriatric Patients With Acute Coronary Syndrome
- ClinicalTrials.gov ID
- NCT07203924
- Acronym / sponsor ID
- 2024/192 (BU Ethics No)
- Keywords
- Acute Coronary Syndrome, TIMI, HEART, SVEAT, Physical Activity
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 207 participants (actual)
- Lead sponsor
- Balikesir UniversityUniversity, hospital or other
- Study start
- 4 Dec 2024 (actual)
- Primary completion
- 1 Sep 2025 (actual)
- Study completion
- 11 Sep 2025 (actual)
- First posted
- 2 Oct 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational study evaluated the relationship between physical activity level and prognosis in geriatric patients admitted to the emergency department with acute coronary syndrome (ACS). A total of 207 patients aged 65 years and older were included. Physical activity level was assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF) and compared with clinical outcomes and risk scores (TIMI, HEART, SVEAT). Results showed that patients with higher physical activity levels had lower rates of major adverse cardiac events (MACE) and mortality, as well as lower risk scores. The findings suggest that physical activity is an independent protective factor that improves prognosis in older patients with ACS.
Detailed description
Acute coronary syndrome (ACS) in elderly patients is associated with high morbidity and mortality, and identifying prognostic factors is clinically important. Physical activity is known to have protective cardiovascular effects, but its prognostic role in geriatric ACS patients remains unclear.
This observational study will include 207 patients aged 65 years and older who present to the emergency department with ACS. Physical activity levels will be measured using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). Activity scores will then be compared with clinical outcomes, including major adverse cardiac events (MACE), mortality, and risk stratification scores (TIMI, HEART, SVEAT).
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Geriatric ACS Patients | – | –This cohort consists of 207 patients aged 65 years and older who presented to the emergency department with acute coronary syndrome (ACS). No intervention was performed. Physical activity levels were assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), and outcomes were compared with major adverse cardiac events (MACE), mortality, and risk scores (TIMI, HEART, SVEAT). |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- The study population consisted of 207 geriatric patients aged 65 years and older who were admitted to the emergency department with a diagnosis of acute coronary syndrome (ACS)
Key inclusion criteria (3 listed)
- Age ≥ 65 years
- Admission to the emergency department with a diagnosis of acute coronary syndrome (ACS)
- Ability to complete the International Physical Activity Questionnaire-Short Form (IPAQ-SF)
Key exclusion criteria (3 listed)
- Age < 65 years
- Patients without ACS diagnosis
- Patients unable to complete the IPAQ-SF questionnaire (e.g., due to severe cognitive impairment or communication problems)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Major Adverse Cardiac Events (MACE)
Time frame: Within 30 days after emergency department admission
Occurrence of major adverse cardiac events (MACE) including STEMI, NSTEMI, unstable angina, or cardiovascular mortality.
5 secondary outcomes
Physical Activity Score (IPAQ-SF)
Time frame: At baseline (hospital admission, emergency department evaluation)
TIMI Risk Score
Time frame: At baseline (emergency department evaluation)
HEART Risk Score
Time frame: At baseline (emergency department evaluation)
SVEAT Risk Score
Time frame: At baseline (emergency department evaluation)
All-cause Mortality
Time frame: Within 30 days after admission
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Oct 2025.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared because the study is retrospective and based on hospital records, and data sharing is restricted due to patient privacy and ethical considerations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Acute Coronary Syndromes and Geriatric Patients, run by Balikesir University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Major Adverse Cardiac Events (MACE) (time frame: Within 30 days after emergency department admission). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Oct 2025.