Obesity & OverweightLog2LoseAINCT07225426
Personalizing Financial Incentives
A study testing personalized financial incentives in people with Obesity & Overweight, run by University of Utah at 1 site in United States.
Trial summary
The purpose of this study is to determine the feasibility of providing personalized incentives for dietary self-monitoring and/or interim weight loss to people enrolled in a weight-loss program Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Obesity & Overweight
- What is being tested?
- personalized financial incentives
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 94 participants
- Where
- 1 siteUnited States
- Study dates
- 4 Feb 2026to 28 Feb 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Willing to attend virtual baseline and follow-up data collection visits
- At least 18 years of age
- Verified obesity as defined as a BMI ≥30 kg/m2
- Agree to attend 13 biweekly group classes (virtual) delivered by a registered dietitian
- Agree to review study materials between classes
- Regular access to an unshared smart phone
Show all 13Show fewer
- Reliable access to internet
- Able to speak and read English
- Desire to lose weight
- Able to connect to a video conference call using a smartphone, tablet or computer with a webcam and microphone
- Ability to download and use Fitbit app daily
- Have or be willing to create a Gmail address
- Physical ability to stand on a scale without support
Who cannot join
- Weight loss of at least 10lbs in the month prior to screening
- Weight > 380lbs
- Currently enrolled or enrolled in the previous month in a clinical, research, or community program focusing on lifestyle change that could affect weight
- New user of weight loss medication
- Pregnant, lactating or planning on becoming pregnant during the study
- History of bariatric procedure or planning to have bariatric procedure in the study timeframe
Show all 19Show fewer
- Residing in a nursing home, skilled nursing facility or assisted living facility
- Impaired hearing
- Significant dementia, drug or alcohol abuse, or unstable psychiatric illness (e.g., schizophrenia, psychosis)
- Current treatment for cancer or being treated for cancer (besides basal cell carcinoma or squamous cell) in the last 6 months
- Use of insulin, sulfonylureas, or meglitinides due to increased risk for hypoglycemia
- Diuretic medication doses higher than hydrochlorothiazide or chlorthalidone 25 mg daily, furosemide 40 mg daily, torsemide 20 mg daily, bumetanide 1 mg daily, or any use of metolazone; use of potassium-sparing diuretics is acceptable
- Unstable heart disease in the 6 months prior to screening
- Chronic kidney disease at stage 4 or higher
- Exertional chest pain
- Pain, fainting, or other conditions that prohibit mild/moderate exercise
- History of ascites requiring paracentesis
- Inducing vomiting to prevent weight gain or counteract the effects of eating an average of 1 time per week or more in the past 3 months*
- Not suitable for study participation due to other reasons at the discretion of the investigators
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Log2LoseAI: Reinforcement Learning to Create a Framework for Personalizing Financial Incentives
The purpose of this study is to determine the feasibility of providing personalized incentives for dietary self-monitoring and/or interim weight loss to people enrolled in a weight-loss program
Read the detailed description
In this study, community outpatients will participate in a clinician-facilitated, group-based behavioral weight-loss program for 24 weeks. Dietary self-monitoring data (input by patients via a mobile phone dietary application) and weight data (input by patients via cellular scale) will be collected by a software platform. A reinforcement learning algorithm will use data collected during the trial to predict which participants will respond to a financial incentive. Incentives will be provided to participants predicted to respond, and they will be notified of incentives via text messaging.
- Conditions
- Obesity & Overweight
- Being tested
- personalized financial incentives
- Keywords
- behavioral intervention, obesity, financial incentives, reinforcement learning, artificial intelligence
- Medical subject headings
- Obesity, Overweight
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
personalized financial incentivesBehavioural
Every week, a reinforcement learning algorithm will process data on weight loss, calorie logging, and incentives earned to predict that their weight loss is positively influenced by incentives.
| Study group | Role | What they receive |
|---|---|---|
| Personalized incentives | Experimental | Participants may receive financial incentives for weight loss if their performance suggests they respond to financial incentives. Receives: Behavioral: personalized financial incentives |
What is being measured
The primary outcome is the main question the study is designed to answer.
Screening-to-enrollment ratio
number of potential participants screened for the study/ number of participants who provide a baseline weight for the intervention
Measured: Week 0
Retention for outcomes
number of participants who provide a weight at 25 weeks/number of participants who provide a baseline weight for the intervention
Measured: 25 weeks
Secondary outcomes (3)
Adherence to calorie logging
Proportion of weeks participants achieve adequate calorie logging (5 days per week)
Measured: 24 weeks
Adherence to self-weighing
Proportion of weeks participants weigh at least twice per week on a study-provided cellular scale
Measured: 24 weeks
Body weight
Changes in body weight from baseline to week 25, measured by study-provided cellular scales
Measured: baseline to 25 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Nov 2025
- Study start4 Feb 2026
- Primary completion28 Feb 2027 (estimated)
- Study completion28 Feb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obesity & OverweightStudies of the same condition, open and under way.
- More trials run by University of UtahThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 94 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Utah
- Sponsor type
- University, hospital or other
- Collaborators
- National Heart, Lung, and Blood Institute (NHLBI)
- Responsible party
- Principal investigator, Corrine Voils, University of Utah
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07225426
- Sponsor's protocol ID
- 00188990
- Other IDs
- R34HL170205
- Acronym
- Log2LoseAI
- Status last verified
- Aug 2026
- First submitted
- 4 Nov 2025
- Last updated
- 13 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: This study will collect weight data from the cellular-connect scales, calorie logging data from the dietary tracking app, and self-reported survey data including demographics and behavioral measures. Additional data will include binary indicators for whether participants earned an incentive each week of the study and how much they earned, generated by algorithms created by the research team using scale and dietary tracking app data.
Study at a glance
From the registry record, last updated by the sponsor on 13 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Log2LoseAI: Reinforcement Learning to Create a Framework for Personalizing Financial Incentives
- ClinicalTrials.gov ID
- NCT07225426
- Acronym / sponsor ID
- Log2LoseAI / 00188990
- Conditions
- Obesity & Overweight
- Keywords
- behavioral intervention, obesity, financial incentives, reinforcement learning, artificial intelligence
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 94 participants (actual)
- Lead sponsor
- University of UtahUniversity, hospital or other
- Collaborators
- National Heart, Lung, and Blood Institute (NHLBI)
- Study start
- 4 Feb 2026 (actual)
- Primary completion
- 28 Feb 2027 (estimated)
- Study completion
- 28 Feb 2027 (estimated)
- First posted
- 6 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to determine the feasibility of providing personalized incentives for dietary self-monitoring and/or interim weight loss to people enrolled in a weight-loss program
Detailed description
In this study, community outpatients will participate in a clinician-facilitated, group-based behavioral weight-loss program for 24 weeks. Dietary self-monitoring data (input by patients via a mobile phone dietary application) and weight data (input by patients via cellular scale) will be collected by a software platform. A reinforcement learning algorithm will use data collected during the trial to predict which participants will respond to a financial incentive. Incentives will be provided to participants predicted to respond, and they will be notified of incentives via text messaging.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Personalized incentives | Experimental | Behavioral: personalized financial incentivesParticipants may receive financial incentives for weight loss if their performance suggests they respond to financial incentives. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (13 listed)
- Willing to attend virtual baseline and follow-up data collection visits
- At least 18 years of age
- Verified obesity as defined as a BMI ≥30 kg/m2
- Agree to attend 13 biweekly group classes (virtual) delivered by a registered dietitian
- Agree to review study materials between classes
Key exclusion criteria (19 listed)
- Weight loss of at least 10lbs in the month prior to screening
- Weight > 380lbs
- Currently enrolled or enrolled in the previous month in a clinical, research, or community program focusing on lifestyle change that could affect weight
- New user of weight loss medication
- Pregnant, lactating or planning on becoming pregnant during the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| personalized financial incentivesEvery week, a reinforcement learning algorithm will process data on weight loss, calorie logging, and incentives earned to predict that their weight loss is positively influenced by incentives. | Behavioural | Personalized incentives |
Primary outcome
Screening-to-enrollment ratio
Time frame: Week 0
number of potential participants screened for the study/ number of participants who provide a baseline weight for the intervention
Retention for outcomes
Time frame: 25 weeks
number of participants who provide a weight at 25 weeks/number of participants who provide a baseline weight for the intervention
3 secondary outcomes
Adherence to calorie logging
Time frame: 24 weeks
Adherence to self-weighing
Time frame: 24 weeks
Body weight
Time frame: baseline to 25 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Aug 2026.
- Individual participant dataSharing planned: Yes. This study will collect weight data from the cellular-connect scales, calorie logging data from the dietary tracking app, and self-reported survey data including demographics and behavioral measures. Additional data will include binary indicators for whether participants earned an incentive each week of the study and how much they earned, generated by algorithms created by the research team using scale and dietary tracking app data.
Related trials for Obesity & Overweight
Not yet recruitingObservational study
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism
Healthy Volunteer, Obestity
RecruitingPhase 3
Trial to Evaluate ALN-CIDEB in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD
Recruiting
Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change
Overweight, Obesity
Not yet recruitingObservational study
Brain and Obesity Longitudinal Development: Neurobiological Mechanisms of Semaglutide Treatment of Adolescent Obesity
Pediatric Obesity, Obesity
Not yet recruitingObservational study
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
Obesity, Diabetes
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing personalized financial incentives in people with Obesity & Overweight, run by University of Utah at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 13 inclusion and 19 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 13 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Screening-to-enrollment ratio (time frame: Week 0). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Aug 2026.