LymphedemaNCT07240324
The Effect of LymphaTouch® and Manual Lymphatic Drainage on Extremity Circumference Measurements in Lymphedema
An observational study of Lymphedema, run by Istanbul Physical Medicine Rehabilitation Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
This retrospective study will be conducted using the medical records of lymphedema patients followed in the Physical Medicine and Rehabilitation outpatient clinics and lymphedema unit of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Lymphedema
- How many people
- 172 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 10 Oct 2025to 10 Nov 2025
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Adult, Older adult
Study population: ChatGPT: The study population consists of patients with lymphedema who received either LymphaTouch® or Manual Lymphatic Drainage (MLD) treatment.
Who may be able to join
- Clinically diagnosed with lymphedema
- Aged between 18 and 75 years
- Complete pre- and post-treatment extremity circumference measurements available in patient records
Who cannot join
- History of systemic diseases such as diabetes, rheumatologic disorders, or malignancy
- Presence of neurological disorders (e.g., polyneuropathy, multiple sclerosis, history of stroke)
- Pregnancy
- History of surgery or major trauma involving the affected limb within the past 6 months
- History of injection therapy or physical therapy applied to the same limb within the past 6 months
- History of infection or active dermatological disease affecting the limb
- Incomplete or inconsistent data in patient records
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Istanbul
About this study
Official title: The Effect of LymphaTouch® and Manual Lymphatic Drainage on Extremity Circumference Measurements in Lymphedema: A Retrospective Study
This retrospective study will be conducted using the medical records of lymphedema patients followed in the Physical Medicine and Rehabilitation outpatient clinics and lymphedema unit of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. Women and men aged 18-75 years with a diagnosis of upper or lower extremity lymphedema will be included. Sociodemographic and clinical data of the patients will be recorded, and participants will be divided into two treatment groups: those who received LymphaTouch® therapy and those who underwent Manual Lymphatic Drainage (MLD). Pre- and post-treatment extremity circumference measurements will be obtained from patient records, and the differences between the groups will be compared.
- Conditions
- Lymphedema
- Being tested
- No intervention
- Medical subject headings
- Lymphedema
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No interventionOther
No intervention
| Study group | Role | What they receive |
|---|---|---|
| MLD group | Patients with lympedema who received MLD treatment Receives: Other: No intervention | |
| Lymphatouch group | Patients with lympedema who received Lymphatouch treatment Receives: Other: No intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Extremity Circumference (cm):
he primary outcome will be the difference in limb circumference measurements before and after treatment. Circumference values will be obtained from standardized anatomical landmarks, including the wrist/ankle, and at 10 cm, 20 cm, 30 cm, and 40 cm proximal to the metatarsophalangeal (MTP) or metacarpophalangeal (MCP) joint. A greater reduction in circumference indicates a more effective treatment response.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Nov 2025
- Study start10 Oct 2025
- Primary completion10 Oct 2025
- Study completion10 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for LymphedemaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Other
- Enrolment
- 172 participants (actual)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07240324
- Sponsor's protocol ID
- istftreah2
- Status last verified
- Nov 2025
- First submitted
- 16 Nov 2025
- Last updated
- 20 Nov 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of LymphaTouch® and Manual Lymphatic Drainage on Extremity Circumference Measurements in Lymphedema: A Retrospective Study
- ClinicalTrials.gov ID
- NCT07240324
- Acronym / sponsor ID
- istftreah2
- Conditions
- Lymphedema
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 172 participants (actual)
- Lead sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research HospitalOther government
- Study start
- 10 Oct 2025 (actual)
- Primary completion
- 10 Oct 2025 (actual)
- Study completion
- 10 Nov 2025 (actual)
- First posted
- 20 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This retrospective study will be conducted using the medical records of lymphedema patients followed in the Physical Medicine and Rehabilitation outpatient clinics and lymphedema unit of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. Women and men aged 18-75 years with a diagnosis of upper or lower extremity lymphedema will be included. Sociodemographic and clinical data of the patients will be recorded, and participants will be divided into two treatment groups: those who received LymphaTouch® therapy and those who underwent Manual Lymphatic Drainage (MLD). Pre- and post-treatment extremity circumference measurements will be obtained from patient records, and the differences between the groups will be compared.
Study design
- Observational model
- Cohort
- Time perspective
- Other
- Target follow-up
- 1 Day
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| MLD group | – | Other: No interventionPatients with lympedema who received MLD treatment |
| Lymphatouch group | – | Other: No interventionPatients with lympedema who received Lymphatouch treatment |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- ChatGPT: The study population consists of patients with lymphedema who received either LymphaTouch® or Manual Lymphatic Drainage (MLD) treatment.
Key inclusion criteria (3 listed)
- Clinically diagnosed with lymphedema
- Aged between 18 and 75 years
- Complete pre- and post-treatment extremity circumference measurements available in patient records
Key exclusion criteria (7 listed)
- History of systemic diseases such as diabetes, rheumatologic disorders, or malignancy
- Presence of neurological disorders (e.g., polyneuropathy, multiple sclerosis, history of stroke)
- Pregnancy
- History of surgery or major trauma involving the affected limb within the past 6 months
- History of injection therapy or physical therapy applied to the same limb within the past 6 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No interventionNo intervention | Other | Lymphatouch group, MLD group |
Primary outcome
Change in Extremity Circumference (cm):
Time frame: Baseline
he primary outcome will be the difference in limb circumference measurements before and after treatment. Circumference values will be obtained from standardized anatomical landmarks, including the wrist/ankle, and at 10 cm, 20 cm, 30 cm, and 40 cm proximal to the metatarsophalangeal (MTP) or metacarpophalangeal (MCP) joint. A greater reduction in circumference indicates a more effective treatment response.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Nov 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Lymphedema, run by Istanbul Physical Medicine Rehabilitation Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Extremity Circumference (cm): (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Nov 2025.